{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T12:18:09Z","timestamp":1794572289591,"version":"4.9.1"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,11]],"date-time":"2024-04-11T00:00:00Z","timestamp":1712793600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["eClinicalMedicine"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.eclinm.2024.102614","type":"journal-article","created":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T23:31:51Z","timestamp":1714692711000},"page":"102614","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"special_numbering":"C","title":["Projecting the clinical burden of chronic kidney disease at the patient level (Inside CKD): a microsimulation modelling study"],"prefix":"10.1016","volume":"72","author":[{"given":"Glenn M.","family":"Chertow","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Correa-Rotter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai-Uwe","family":"Eckardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiichiro","family":"Kanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avraham","family":"Karasik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1970-9979","authenticated-orcid":false,"given":"Guisen","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian Fynbo","family":"Christiansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panos","family":"Stafylas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen G.","family":"Holt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernst C.","family":"Hagen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6546-7769","authenticated-orcid":false,"given":"Juan Jose","family":"Garcia Sanchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Barone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Cabrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Nolan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Coker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8976-1919","authenticated-orcid":false,"given":"Laura","family":"Webber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lise","family":"Retat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10225","key":"10.1016\/j.eclinm.2024.102614_bib1","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0140-6736(20)30045-3","article-title":"Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"395","author":"Bikbov","year":"2020","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.eclinm.2024.102614_bib2","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1373\/clinchem.2012.184259","article-title":"The kidney disease improving global outcomes (KDIGO) guideline update for chronic kidney disease: evolution not revolution","volume":"59","author":"Lamb","year":"2013","journal-title":"Clin Chem"},{"issue":"10","key":"10.1016\/j.eclinm.2024.102614_bib3","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1093\/ckj\/sfac151","article-title":"Ageing meets kidney disease","volume":"15","author":"Ortiz","year":"2022","journal-title":"Clin Kidney J"},{"issue":"7","key":"10.1016\/j.eclinm.2024.102614_bib4","doi-asserted-by":"crossref","first-page":"2607","DOI":"10.1093\/ndt\/gfs095","article-title":"CKD progression: a risky business","volume":"27","author":"Chang","year":"2012","journal-title":"Nephrol Dial Transplant"},{"issue":"21","key":"10.1016\/j.eclinm.2024.102614_bib5","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1001\/2013.jamainternmed.85","article-title":"Body mass index in 1.2 million adolescents and risk for end-stage renal disease","volume":"172","author":"Vivante","year":"2012","journal-title":"Arch Intern Med"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102614_bib6","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1053\/j.ajkd.2018.12.044","article-title":"Hypertension in CKD: core curriculum 2019","volume":"74","author":"Ku","year":"2019","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.eclinm.2024.102614_bib7","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.c4249","article-title":"Low glomerular filtration rate and risk of stroke: meta-analysis","volume":"341","author":"Lee","year":"2010","journal-title":"BMJ"},{"issue":"10","key":"10.1016\/j.eclinm.2024.102614_bib8","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1093\/eurheartj\/ehi880","article-title":"Chronic kidney disease and risk of incident myocardial infarction and all-cause and cardiovascular disease mortality in middle-aged men and women from the general population","volume":"27","author":"Meisinger","year":"2006","journal-title":"Eur Heart J"},{"issue":"8","key":"10.1016\/j.eclinm.2024.102614_bib9","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.116.003825","article-title":"Heart failure increases the risk of adverse renal outcomes in patients with normal kidney function","volume":"10","author":"George","year":"2017","journal-title":"Circ Heart Fail"},{"issue":"Suppl 1","key":"10.1016\/j.eclinm.2024.102614_bib10","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1186\/s12877-020-01697-3","article-title":"Impaired kidney function is associated with lower quality of life among community-dwelling older adults : the screening for CKD among older people across Europe (SCOPE) study","volume":"20","author":"Artzi-Medvedik","year":"2020","journal-title":"BMC Geriatr"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102614_bib11","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1186\/s12955-020-01559-x","article-title":"Health related quality of life utility weights for economic evaluation through different stages of chronic kidney disease: a systematic literature review","volume":"18","author":"Cooper","year":"2020","journal-title":"Health Qual Life Outcome"},{"issue":"10159","key":"10.1016\/j.eclinm.2024.102614_bib12","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1016\/S0140-6736(18)31694-5","article-title":"Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016-40 for 195 countries and territories","volume":"392","author":"Foreman","year":"2018","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.eclinm.2024.102614_bib13","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1093\/ckj\/sfab240","article-title":"More on the invisibility of chronic kidney disease and counting","volume":"15","author":"Carriazo","year":"2022","journal-title":"Clin Kidney J"},{"issue":"10","key":"10.1016\/j.eclinm.2024.102614_bib14","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1093\/ckj\/sfab016","article-title":"Prevalence, recognition and management of chronic kidney disease in Japan: population-based estimate using a healthcare database with routine health checkup data","volume":"14","author":"Takeuchi","year":"2021","journal-title":"Clin Kidney J"},{"issue":"10","key":"10.1016\/j.eclinm.2024.102614_bib15","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1038\/s41366-018-0295-7","article-title":"Screening and brief intervention for obesity in primary care: cost-effectiveness analysis in the BWeL trial","volume":"43","author":"Retat","year":"2019","journal-title":"Int J Obes"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102614_bib16","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s12325-022-02353-5","article-title":"Projecting the epidemiological and economic impact of chronic kidney disease using patient-level microsimulation modelling: rationale and methods of inside CKD","volume":"40","author":"Tangri","year":"2023","journal-title":"Adv Ther"},{"key":"10.1016\/j.eclinm.2024.102614_bib17","doi-asserted-by":"crossref","unstructured":"Chadban S, Ar\u0131c\u0131 M, Power A, et al. Projecting the economic burden of chronic kidney disease at the patient level (Inside CKD): a microsimulation modelling study. eClinMed. 2024.","DOI":"10.2139\/ssrn.4636227"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102614_bib18","first-page":"1","article-title":"Kidney disease: improving global outcomes (KDIGO) CKD work group. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease","volume":"3","author":"Levin","year":"2013","journal-title":"Kidney Int Suppl"},{"issue":"6","key":"10.1016\/j.eclinm.2024.102614_bib19","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1093\/ckj\/sfab046","article-title":"Methods and rationale of the DISCOVER CKD global observational study","volume":"14","author":"Pecoits-Filho","year":"2021","journal-title":"Clin Kidney J"},{"issue":"5","key":"10.1016\/j.eclinm.2024.102614_bib20","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1177\/0272989X12454579","article-title":"Model transparency and validation: a report of the ISPOR-SMDM modeling Good research practices task force-7","volume":"32","author":"Eddy","year":"2012","journal-title":"Med Decis Making"},{"key":"10.1016\/j.eclinm.2024.102614_bib21","article-title":"Prevalence, outcomes, and cost of chronic kidney disease in a contemporary population of 2.4 million patients from 11 countries: the CaReMe CKD study","volume":"20","author":"Sundstr\u00f6m","year":"2022","journal-title":"Lancet Reg Health Eur"},{"issue":"5","key":"10.1016\/j.eclinm.2024.102614_bib22","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2022-067386","article-title":"Prevalence of undiagnosed stage 3 chronic kidney disease in France, Germany, Italy, Japan and the USA: results from the multinational observational REVEAL-CKD study","volume":"13","author":"Tangri","year":"2023","journal-title":"BMJ Open"},{"issue":"suppl 1","key":"10.1016\/j.eclinm.2024.102614_bib23","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1159\/000515329","article-title":"The global kidney health atlas: burden and opportunities to improve kidney health worldwide","volume":"76","author":"Bharati","year":"2020","journal-title":"Ann Nutr Metabol"},{"issue":"9981","key":"10.1016\/j.eclinm.2024.102614_bib24","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1016\/S0140-6736(14)61601-9","article-title":"Worldwide access to treatment for end-stage kidney disease: a systematic review","volume":"385","author":"Liyanage","year":"2015","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.eclinm.2024.102614_bib25","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1053\/j.ajkd.2010.11.010","article-title":"Sustainable community-based CKD screening methods employed by the national kidney foundation\u2019s kidney early evaluation program (KEEP)","volume":"57","author":"McCullough","year":"2011","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.eclinm.2024.102614_bib26","doi-asserted-by":"crossref","first-page":"S50","DOI":"10.1046\/j.1523-1755.63.s83.11.x","article-title":"Identification of persons at high risk for kidney disease via targeted screening: the NKF Kidney Early Evaluation Program","volume":"63","author":"Brown","year":"2003","journal-title":"Kidney Int"},{"issue":"17","key":"10.1016\/j.eclinm.2024.102614_bib27","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1161\/CIRCULATIONAHA.118.038868","article-title":"Comparison of the effects of glucagon-like peptide receptor agonists and sodium-glucose cotransporter 2 inhibitors for prevention of major adverse cardiovascular and renal outcomes in type 2 diabetes mellitus","volume":"139","author":"Zelniker","year":"2019","journal-title":"Circulation"},{"issue":"8","key":"10.1016\/j.eclinm.2024.102614_bib28","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1111\/dom.14401","article-title":"Prevalence and progression of chronic kidney disease among patients with type 2 diabetes: insights from the DISCOVER study","volume":"23","author":"Khunti","year":"2021","journal-title":"Diabetes Obes Metabol"},{"issue":"8","key":"10.1016\/j.eclinm.2024.102614_bib30","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.2215\/CJN.00500111","article-title":"Racial and ethnic differences in mortality among individuals with chronic kidney disease: results from the Kidney Early Evaluation Program (KEEP)","volume":"6","author":"Jolly","year":"2011","journal-title":"Clin J Am Soc Nephrol"}],"container-title":["eClinicalMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589537024001937?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589537024001937?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,7]],"date-time":"2024-07-07T15:22:42Z","timestamp":1720365762000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589537024001937"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":29,"alternative-id":["S2589537024001937"],"URL":"https:\/\/doi.org\/10.1016\/j.eclinm.2024.102614","relation":{},"ISSN":["2589-5370"],"issn-type":[{"value":"2589-5370","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Projecting the clinical burden of chronic kidney disease at the patient level (Inside CKD): a microsimulation modelling study","name":"articletitle","label":"Article Title"},{"value":"eClinicalMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eclinm.2024.102614","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"102614"}}