{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:45:26Z","timestamp":1790646326845,"version":"4.1.0"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T00:00:00Z","timestamp":1725494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["eClinicalMedicine"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.eclinm.2024.102843","type":"journal-article","created":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T09:57:08Z","timestamp":1727171828000},"page":"102843","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"special_numbering":"C","title":["Comparative efficacy, safety and benefit\/risk of alerting agents for excessive daytime sleepiness in patients with obstructive sleep apnoea: a network meta-analysis"],"prefix":"10.1016","volume":"76","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3832-2358","authenticated-orcid":false,"given":"Jean-Louis","family":"P\u00e9pin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Lehert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raoua","family":"Ben Messaoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Joyeux-Faure","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Causs\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9573-9478","authenticated-orcid":false,"given":"Jerryll","family":"Asin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferran","family":"Barb\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4875-7796","authenticated-orcid":false,"given":"Maria R.","family":"Bonsignore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Winfried","family":"Randerath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Verbraecken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonya","family":"Craig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Dauvilliers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.eclinm.2024.102843_bib1","article-title":"Obstructive sleep apnoea syndrome","volume":"1","author":"L\u00e9vy","year":"2015","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.eclinm.2024.102843_bib2","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1513\/AnnalsATS.202006-696FR","article-title":"Excessive daytime sleepiness in obstructive sleep apnea. Mechanisms and clinical management","volume":"18","author":"Lal","year":"2021","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.eclinm.2024.102843_bib3","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S2213-2600(19)30198-5","article-title":"Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis","volume":"7","author":"Benjafield","year":"2019","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib4","article-title":"Changes in the societal burden caused by sleep apnoea in Finland from 1996 to 2018: a national registry study","volume":"16","author":"Mattila","year":"2022","journal-title":"Lancet Reg Health Eur"},{"key":"10.1016\/j.eclinm.2024.102843_bib5","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2021.690008","article-title":"Excessive daytime sleepiness in obstructive sleep apnea patients treated with continuous positive airway pressure: data from the European sleep apnea database","volume":"12","author":"Bonsignore","year":"2021","journal-title":"Front Neurol"},{"key":"10.1016\/j.eclinm.2024.102843_bib6","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.sleep.2023.10.001","article-title":"Recommendations for clinical management of excessive daytime sleepiness in obstructive sleep apnoea - a Delphi consensus study","volume":"112","author":"Steier","year":"2023","journal-title":"Sleep Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib7","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1080\/00325481.2021.1948305","article-title":"Residual excessive daytime sleepiness in patients treated for obstructive sleep apnea: guidance for assessment, diagnosis, and management","volume":"133","author":"Rosenberg","year":"2021","journal-title":"Postgrad Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib8","article-title":"Guidelines for the assessment and management of residual sleepiness in obstructive apnea-hypopnea syndrome: endorsed by the French sleep research and medicine society (SFRMS) and the French speaking society of respiratory diseases (SPLF)","volume":"86","author":"Barateau","year":"2024","journal-title":"Respir Med Res"},{"key":"10.1016\/j.eclinm.2024.102843_bib9","doi-asserted-by":"crossref","DOI":"10.1183\/16000617.0230-2021","article-title":"Investigation and management of residual sleepiness in CPAP-treated patients with obstructive sleep apnoea: the European view","volume":"31","author":"Craig","year":"2022","journal-title":"Eur Respir Rev"},{"key":"10.1016\/j.eclinm.2024.102843_bib10","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.pnpbp.2007.10.016","article-title":"Placebo and moda\ufb01nil effect on sleepiness in obstructive sleep apnea","volume":"32","author":"Bittencourt","year":"2008","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.eclinm.2024.102843_bib11","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1093\/sleep\/28.4.464","article-title":"Moda\ufb01nil for treatment of residual excessive sleepiness in nasal continuous positive airway pressure- treated obstructive sleep apnea\/hypopnea syndrome","volume":"28","author":"Black","year":"2005","journal-title":"Sleep"},{"key":"10.1016\/j.eclinm.2024.102843_bib12","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1136\/thoraxjnl-2013-203796","article-title":"Modafinil improves daytime sleepiness in patients with mild to moderate obstructive sleep apnoea not using standard treatments: a randomised placebo-controlled crossover trial","volume":"69","author":"Chapman","year":"2014","journal-title":"Thorax"},{"key":"10.1016\/j.eclinm.2024.102843_bib13","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S1389-9457(03)00108-4","article-title":"Effects of moda\ufb01nil on sustained attention performance and quality of life in OSA patients with residual sleepiness while being treated with nCPAP","volume":"4","author":"Dinges","year":"2003","journal-title":"Sleep Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib14","doi-asserted-by":"crossref","first-page":"143","DOI":"10.5664\/jcsm.3440","article-title":"Effect of armoda\ufb01nil on cortical activity and working memory in patients with residual excessive sleepiness associated with CPAP-treated OSA: a multicenter fMRI study","volume":"10","author":"Greve","year":"2014","journal-title":"J\u00a0Clin Sleep Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib15","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/j.sleep.2013.04.010","article-title":"Alertness and psychomotor performance effects of the histamine-3 inverse agonist MK-0249 in obstructive sleep apnea patients on continuous positive airway pressure therapy with excessive daytime sleepiness: a randomized adaptive crossover study","volume":"14","author":"Herring","year":"2013","journal-title":"Sleep Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib16","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.rmed.2006.06.007","article-title":"Adjunct armoda\ufb01nil improves wakefulness and memory in obstructive sleep apnea\/hypopnea syndrome","volume":"101","author":"Hirshkowitz","year":"2007","journal-title":"Respir Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib17","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.sleep.2016.06.035","article-title":"Findings of the maintenance of wakefulness test and its relationship with response to modafinil therapy for residual excessive daytime sleepiness in obstructive sleep apnea patients adequately treated with nasal continuous positive airway pressure","volume":"27-28","author":"Inoue","year":"2016","journal-title":"Sleep Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib18","doi-asserted-by":"crossref","first-page":"751","DOI":"10.5664\/jcsm.2912","article-title":"Ef\ufb01cacy and safety of adjunctive moda\ufb01nil treatment on residual excessive daytime sleepiness among nasal continuous positive airway pressure-treated Japanese patients with obstructive sleep apnea syndrome: a double-blind placebo-controlled study","volume":"9","author":"Inoue","year":"2013","journal-title":"J\u00a0Clin Sleep Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib19","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1164\/ajrccm.163.4.2005036","article-title":"Randomized, double-blind, placebo-controlled crossover trial of moda\ufb01nil in the treatment of residual excessive daytime sleepiness in the sleep apnea\/hypopnea syndrome","volume":"163","author":"Kingshott","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib20","doi-asserted-by":"crossref","first-page":"32","DOI":"10.4088\/JCP.09m05536gry","article-title":"A\u00a0double-blind, placebo- controlled study of armoda\ufb01nil for excessive sleepiness in patients with treated obstructive sleep apnea and comorbid depression","volume":"71","author":"Krystal","year":"2010","journal-title":"J\u00a0Clin Psychiatry"},{"key":"10.1016\/j.eclinm.2024.102843_bib21","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1164\/ajrccm.164.9.2103032","article-title":"Moda\ufb01nil as adjunct therapy for daytime sleepiness in obstructive sleep apnea","volume":"164","author":"Pack","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib22","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.clinthera.2006.05.013","article-title":"Effects of armoda\ufb01nil in the treatment of residual excessive sleepiness associated with obstructive sleep apnea\/hypopnea syndrome: a 12-week, multicenter, double-blind, randomized, placebo-controlled study in nCPAP- adherent adults","volume":"28","author":"Roth","year":"2006","journal-title":"Clin Ther"},{"key":"10.1016\/j.eclinm.2024.102843_bib23","doi-asserted-by":"crossref","first-page":"499","DOI":"10.5664\/jcsm.27648","article-title":"Modafinil improves functional outcomes in patients with residual excessive sleepiness associated with CPAP treatment","volume":"5","author":"Weaver","year":"2009","journal-title":"J\u00a0Clin Sleep Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib24","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1164\/rccm.200908-1307OC","article-title":"Modafinil effects during acute continuous positive airway pressure withdrawal: a randomized crossover double-blind placebo-controlled trial","volume":"181","author":"Williams","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib25","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.chest.2021.02.033","article-title":"Randomized controlled trial of solriamfetol for excessive daytime sleepiness in OSA: an analysis of subgroups adherent or nonadherent to OSA treatment","volume":"160","author":"Schweitzer","year":"2021","journal-title":"Chest"},{"key":"10.1016\/j.eclinm.2024.102843_bib26","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1164\/rccm.201806-1100OC","article-title":"Solriamfetol for excessive sleepiness in obstructive sleep apnea (TONES 3). A randomized controlled trial","volume":"199","author":"Schweitzer","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib27","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.chest.2018.11.005","article-title":"Solriamfetol for the treatment of excessive sleepiness in OSA: a placebo-controlled randomized withdrawal study","volume":"155","author":"Strollo","year":"2019","journal-title":"Chest"},{"key":"10.1016\/j.eclinm.2024.102843_bib28","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1513\/AnnalsATS.202002-136OC","article-title":"Effects of solriamfetol on quality-of-life measures from a 12-week phase 3 randomized controlled trial","volume":"17","author":"Weaver","year":"2020","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.eclinm.2024.102843_bib29","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1164\/rccm.201907-1284OC","article-title":"Pitolisant for daytime sleepiness in patients with obstructive sleep apnea who refuse continuous positive airway pressure treatment. A randomized trial","volume":"201","author":"Dauvilliers","year":"2020","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib30","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1016\/j.chest.2020.09.281","article-title":"Pitolisant for residual excessive daytime sleepiness in OSA patients adhering to CPAP: a randomized trial","volume":"159","author":"P\u00e9pin","year":"2021","journal-title":"Chest"},{"key":"10.1016\/j.eclinm.2024.102843_bib31","doi-asserted-by":"crossref","first-page":"2543","DOI":"10.5664\/jcsm.9610","article-title":"Indirect treatment comparison of solriamfetol, modafinil, and armodafinil for excessive daytime sleepiness in obstructive sleep apnea","volume":"17","author":"Ronnebaum","year":"2021","journal-title":"J\u00a0Clin Sleep Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib32","doi-asserted-by":"crossref","first-page":"676","DOI":"10.7326\/M22-3473","article-title":"Comparative efficacy and safety of wakefulness-promoting agents for excessive daytime sleepiness in patients with obstructive sleep apnea: a systematic review and network meta-analysis","volume":"176","author":"Pitre","year":"2023","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib33","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.eclinm.2024.102843_bib34","doi-asserted-by":"crossref","DOI":"10.1155\/2011\/514351","article-title":"Armodafinil versus modafinil in patients of excessive sleepiness associated with shift work sleep disorder: a randomized double blind multicentric clinical trial","volume":"2011","author":"Tembe","year":"2011","journal-title":"Neurol Res Int"},{"key":"10.1016\/j.eclinm.2024.102843_bib35","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1093\/sleep\/14.6.540","article-title":"A\u00a0new method for measuring daytime sleepiness: the Epworth sleepiness scale","volume":"14","author":"Johns","year":"1991","journal-title":"Sleep"},{"key":"10.1016\/j.eclinm.2024.102843_bib36","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/0013-4694(82)90142-0","article-title":"Maintenance of wakefulness test: a polysomnographic technique for evaluating treatment efficacy in patients with excessive somnolence","volume":"53","author":"Mitler","year":"1982","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/j.eclinm.2024.102843_bib37","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1093\/sleep\/28.1.113","article-title":"Practice parameters for clinical use of the multiple sleep latency test and the maintenance of wakefulness test. An American academy of sleep medicine report","volume":"28","author":"Littner","year":"2005","journal-title":"Sleep"},{"key":"10.1016\/j.eclinm.2024.102843_bib38","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1046\/j.1365-2869.1997.00039.x","article-title":"A\u00a0behavioral test to assess daytime sleepiness in obstructive sleep apnoea","volume":"6","author":"Bennett","year":"1997","journal-title":"J\u00a0Sleep Res"},{"key":"10.1016\/j.eclinm.2024.102843_bib39","first-page":"835","article-title":"An instrument to measure functional status outcomes for disorders of excessive sleepiness","volume":"20","author":"Weaver","year":"1997","journal-title":"Sleep"},{"key":"10.1016\/j.eclinm.2024.102843_bib40","doi-asserted-by":"crossref","first-page":"337","DOI":"10.3109\/07853890109002087","article-title":"EQ-5D: a measure of health status from the EuroQol Group","volume":"33","author":"Rabin","year":"2001","journal-title":"Ann Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib41","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1097\/00005650-199206000-00002","article-title":"The MOS 36-item short form health survey (SF-36). I. Conceptual framework and item selection","volume":"30","author":"Ware","year":"1992","journal-title":"Med Care"},{"key":"10.1016\/j.eclinm.2024.102843_bib42","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0165-1781(89)90047-4","article-title":"The Pittsburgh sleep quality index: a new instrument for psychiatric research and practice","volume":"28","author":"Buysse","year":"1989","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.eclinm.2024.102843_bib43","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"GRADE: an emerging consensus on rating quality of evidence and strength of recommendations","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"},{"key":"10.1016\/j.eclinm.2024.102843_bib44","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne","year":"2019","journal-title":"BMJ"},{"key":"10.1016\/j.eclinm.2024.102843_bib45","series-title":"R: a language and environment for statistical computing","year":"2021"},{"key":"10.1016\/j.eclinm.2024.102843_bib46","first-page":"1","article-title":"netmeta: an R package for network meta-analysis using frequentist methods","volume":"106","author":"Balduzzi","year":"2023","journal-title":"J\u00a0Stat Soft"},{"key":"10.1016\/j.eclinm.2024.102843_bib47","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1037\/0033-2909.84.5.888","article-title":"Attitude-behavior relations: a theoretical analysis and review of empirical research","volume":"84","author":"Ajzen","year":"1977","journal-title":"Psychol Bull"},{"key":"10.1016\/j.eclinm.2024.102843_bib48","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/0377-2217(86)90167-0","article-title":"Some remarks on the notion of compensation in MCDM","volume":"26","author":"Bouyssou","year":"1986","journal-title":"Eur J Oper Res"},{"key":"10.1016\/j.eclinm.2024.102843_bib49","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.foodqual.2013.07.003","article-title":"Quadratic PLS regression applied to external preference mapping","volume":"32","author":"Cariou","year":"2014","journal-title":"Food Qual Prefer"},{"key":"10.1016\/j.eclinm.2024.102843_bib50","doi-asserted-by":"crossref","first-page":"4353","DOI":"10.1002\/sim.6236","article-title":"Reduce dimension or reduce weights? Comparing two approaches to multi-arm studies in network meta-analysis","volume":"33","author":"R\u00fccker","year":"2014","journal-title":"Stat Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib51","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s12874-015-0060-8","article-title":"Ranking treatments in frequentist network MAL works without resampling methods","volume":"15","author":"R\u00fccker","year":"2015","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.eclinm.2024.102843_bib52","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.jclinepi.2010.03.016","article-title":"Graphical methods and numerical summaries for presenting results from multiple-treatment MAL: an overview and tutorial","volume":"64","author":"Salanti","year":"2011","journal-title":"J\u00a0Clin Epidemiol"},{"key":"10.1016\/j.eclinm.2024.102843_bib53","doi-asserted-by":"crossref","first-page":"445","DOI":"10.5664\/jcsm.2662","article-title":"Effects of armodafinil on simulated driving and self-report measures in obstructive sleep apnea patients prior to treatment with continuous positive airway pressure","volume":"9","author":"Kay","year":"2013","journal-title":"J\u00a0Clin Sleep Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib54","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1159\/000196661","article-title":"Modafinil in obstructive sleep apnea-hypopnea syndrome: a pilot study in 6 patients","volume":"64","author":"Arnulf","year":"1997","journal-title":"Respiration"},{"key":"10.1016\/j.eclinm.2024.102843_bib55","doi-asserted-by":"crossref","first-page":"2192","DOI":"10.1378\/chest.124.6.2192","article-title":"Modafinil as adjunct therapy for daytime sleepiness in obstructive sleep apnea: a 12-week, open-label study","volume":"124","author":"Schartz","year":"2003","journal-title":"Chest"},{"key":"10.1016\/j.eclinm.2024.102843_bib56","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsz220","article-title":"Long-term study of the safety and maintenance of efficacy of solriamfetol (JZP-110) in the treatment of excessive sleepiness in participants with narcolepsy or obstructive sleep apnea","volume":"43","author":"Malhotra","year":"2020","journal-title":"Sleep"},{"key":"10.1016\/j.eclinm.2024.102843_bib57","doi-asserted-by":"crossref","first-page":"659","DOI":"10.5664\/jcsm.8992","article-title":"Effects of solriamfetol in a long-term trial of participants with obstructive sleep apnea who are adherent or nonadherent to airway therapy","volume":"17","author":"Schweitzer","year":"2021","journal-title":"J\u00a0Clin Sleep Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib58","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s11325-008-0175-9","article-title":"The effect of modafinil following acute CPAP withdrawal: a preliminary study","volume":"12","author":"Williams","year":"2008","journal-title":"Sleep Breath"},{"key":"10.1016\/j.eclinm.2024.102843_bib59","series-title":"Statistical power analysis for the behavioral sciences","author":"Cohen","year":"1988"},{"key":"10.1016\/j.eclinm.2024.102843_bib60","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1183\/13993003.01509-2015","article-title":"Modafinil\/armodafinil in obstructive sleep apnoea: a systematic review and meta-analysis","volume":"47","author":"Chapman","year":"2016","journal-title":"Eur Respir J"},{"key":"10.1016\/j.eclinm.2024.102843_bib61","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/j.clinthera.2016.02.004","article-title":"Effects of moda\ufb01nil and armoda\ufb01nil in patients with obstructive sleep apnea: a meta-analysis of randomized controlled trials","volume":"38","author":"Kuan","year":"2016","journal-title":"Clin Ther"},{"key":"10.1016\/j.eclinm.2024.102843_bib62","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsy185","article-title":"Multiple treatment comparison in narcolepsy: a network meta-analysis","volume":"41","author":"Lehert","year":"2018","journal-title":"Sleep"},{"key":"10.1016\/j.eclinm.2024.102843_bib63","first-page":"6302","article-title":"Pharmacological interventions for excessive daytime sleepiness in adults with narcolepsy: a systematic review and network meta-analysis","volume":"11","author":"Chien","year":"2022","journal-title":"J\u00a0Clin Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib64","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s40261-021-01104-8","article-title":"Efficacy of pitolisant 20 mg in reducing excessive daytime sleepiness and Fatigue in patients with obstructive sleep Apnoea syndrome: an individual patient data meta-analysis","volume":"42","author":"Lehert","year":"2022","journal-title":"Clin Drug Investig"},{"key":"10.1016\/j.eclinm.2024.102843_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2021.105522","article-title":"Pitolisant versus placebo for excessive daytime sleepiness in narcolepsy and obstructive sleep apnea: a meta-analysis from randomized controlled trials","volume":"167","author":"Wang","year":"2021","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.eclinm.2024.102843_bib66","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.sleep.2020.09.019","article-title":"Efficacy and safety of solriamfetol for excessive daytime sleepiness in narcolepsy and obstructive sleep apnea: a systematic review and meta-analysis of clinical trials","volume":"75","author":"Subedi","year":"2020","journal-title":"Sleep Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib67","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1002\/pits.20234","article-title":"Effect sizes, confidence intervals, and confidence intervals for effect sizes","volume":"44","author":"Thompson","year":"2007","journal-title":"Psychol Sch"},{"key":"10.1016\/j.eclinm.2024.102843_bib68","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.5664\/jcsm.9384","article-title":"Long-term effects of solriamfetol on quality of life and work productivity in participants with excessive daytime sleepiness associated with narcolepsy or obstructive sleep apnea","volume":"17","author":"Weaver","year":"2021","journal-title":"J\u00a0Clin Sleep Med"},{"key":"10.1016\/j.eclinm.2024.102843_bib69","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.chest.2023.11.017","article-title":"Long-term efficacy and safety of pitolisant for residual sleepiness due to OSA","volume":"165","author":"P\u00e9pin","year":"2024","journal-title":"Chest"},{"key":"10.1016\/j.eclinm.2024.102843_bib70","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s40264-013-0025-y","article-title":"Safety profile of modafinil across a range of prescribing indications, including off-label use, in a primary care setting in England: results of a modified prescription-event monitoring study","volume":"36","author":"Davies","year":"2013","journal-title":"Drug Saf"}],"container-title":["eClinicalMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S258953702400422X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S258953702400422X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T17:00:38Z","timestamp":1732813238000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S258953702400422X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":70,"alternative-id":["S258953702400422X"],"URL":"https:\/\/doi.org\/10.1016\/j.eclinm.2024.102843","relation":{},"ISSN":["2589-5370"],"issn-type":[{"value":"2589-5370","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparative efficacy, safety and benefit\/risk of alerting agents for excessive daytime sleepiness in patients with obstructive sleep apnoea: a network meta-analysis","name":"articletitle","label":"Article Title"},{"value":"eClinicalMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eclinm.2024.102843","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"102843"}}