{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T06:45:45Z","timestamp":1769237145614,"version":"3.49.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1016\/j.ecoenv.2007.11.015","type":"journal-article","created":{"date-parts":[[2008,2,22]],"date-time":"2008-02-22T16:45:15Z","timestamp":1203698715000},"page":"236-241","source":"Crossref","is-referenced-by-count":89,"title":["Delayed rectifier potassium channels are involved in SO2 derivative-induced hippocampal neuronal injury"],"prefix":"10.1016","volume":"72","author":[{"given":"Guangke","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nan","family":"Sang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2007.11.015_bib1","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s00424-004-1266-5","article-title":"The role of apoptotic volume decrease and ionic homeostasis in the activation and repression of apoptosis","volume":"448","author":"Bortner","year":"2004","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib2","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1002\/bdd.2510080408","article-title":"Gastrointestinal metabolism of N-acetylcysteine in the rat, including an assay for sulfite in biological systems","volume":"8","author":"Cotgreave","year":"1987","journal-title":"Biopharm. Drug Dispos."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib3","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1093\/carcin\/9.11.2015","article-title":"Peroxidase catalyzed oxidation of (bi)sulfite: reaction of free radical metabolites of (bi)sulfite with 7,8-dihydroxy-7,8-dihydrobenzo [\u03b1]-pyrene","volume":"9","author":"Curtis","year":"1988","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.ecoenv.2007.11.015_bib4","first-page":"331","article-title":"Advances in study of physiologic effects of endogenous sulfur dioxide and its derivatives","volume":"38","author":"Du","year":"2006","journal-title":"Beijing Da Xue Xue Bao"},{"key":"10.1016\/j.ecoenv.2007.11.015_bib5","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/j.fct.2004.02.016","article-title":"Effects of derivatives of sulfur dioxide on transient outward potassium currents in acutely isolated hippocampal neurons","volume":"42","author":"Du","year":"2004","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib6","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1038\/sj.cdd.4400335","article-title":"Induction of apoptosis by valinomycin: mitochondrial permeability transition causes intracellular acidification","volume":"5","author":"Furlong","year":"1998","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib7","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0065-230X(02)85006-0","article-title":"Cell volume and ion changes during apoptotic cell death","volume":"85","author":"Gomez-Angelats","year":"2002","journal-title":"Adv. Cancer Res."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib8","first-page":"443","article-title":"Regional effects of sulfur dioxide exposure on the guinea pig brain lipids, lipid peroxidation and lipase activity","volume":"2","author":"Haider","year":"1981","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.ecoenv.2007.11.015_bib9","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1002\/tox.1033","article-title":"Effect of sulfur dioxide and particulate pollutants on bronchitis in children\u2014a risk analysis","volume":"16","author":"Herbarth","year":"2001","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib10","doi-asserted-by":"crossref","first-page":"C970","DOI":"10.1152\/ajpcell.2001.280.4.C970","article-title":"Activation of K channels induces apoptosis in vascular smooth muscle cells","volume":"280","author":"Krick","year":"2001","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib11","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3200\/AEOH.58.1.14-22","article-title":"Changes in somatosensory evoked potentials, lipid peroxidation, and antioxidant enzymes in experimental diabetes: effect of sulfur dioxide","volume":"58","author":"Kucukatay","year":"2003","journal-title":"Arch. Environ. Health"},{"key":"10.1016\/j.ecoenv.2007.11.015_bib12","first-page":"267","article-title":"Effect of SO2 derivatives on sodium currents in acutely isolated rat hippocampal CA1 neurons","volume":"54","author":"Meng","year":"2002","journal-title":"Acta Physiol. Sinica"},{"key":"10.1016\/j.ecoenv.2007.11.015_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1382-6689(02)00106-0","article-title":"Oxidative damage of sulfur dioxide inhalation on brains and livers of mice","volume":"13","author":"Meng","year":"2003","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib14","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1093\/mutage\/geh058","article-title":"DNA damaging effects of sulfur dioxide derivatives in cells from various organs of mice","volume":"19","author":"Meng","year":"2004","journal-title":"Mutagenesis"},{"key":"10.1016\/j.ecoenv.2007.11.015_bib15","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/em.20142","article-title":"DNA damage in mice treated with sulfur dioxide by inhalation","volume":"46","author":"Meng","year":"2005","journal-title":"Environ. Mol. Mutagen."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib16","doi-asserted-by":"crossref","first-page":"2930","DOI":"10.4049\/jimmunol.152.6.2930","article-title":"Intracellular infection by Leishmania donovani inhibits macrophage apoptosis","volume":"152","author":"Moore","year":"1994","journal-title":"J. Immunol."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib17","doi-asserted-by":"crossref","first-page":"C799","DOI":"10.1152\/ajpcell.1995.268.4.C799","article-title":"Physiological roles and properties of potassium channels in arterial smooth muscle","volume":"268","author":"Nelson","year":"1995","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib18","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0006-8993(02)02655-0","article-title":"Disparity between ionic mediators of volume regulation and apoptosis in N1E 115 mouse neuroblastoma cells","volume":"943","author":"O\u2019Reilly","year":"2002","journal-title":"Brain Res."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib19","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1152\/jn.2002.88.3.1119","article-title":"Spontaneous miniature hyperpolarizations affect threshold for action potential generation in mudpuppy cardiac neurons","volume":"88","author":"Parsons","year":"2002","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib20","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0014-5793(98)00099-4","article-title":"Sulphite enhances peroxynitrite-dependent \u03b11-antiproteinase in activation. A mechanism of Lung injury by sulphur dioxide","volume":"423","author":"Reist","year":"1998","journal-title":"FEBS Lett."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib21","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S1383-5718(00)00142-X","article-title":"Chromosome aberrations and sister chromatid exchanges in cultured human lymphocytes treated with sodium metabisulfite, a food preservative","volume":"490","author":"Renc\u00fczo\u011fullari","year":"2001","journal-title":"Mutat. Res."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib22","doi-asserted-by":"crossref","first-page":"9858","DOI":"10.1523\/JNEUROSCI.2392-05.2005","article-title":"Postsynaptically synthesized prostaglandin E2 modulates hippocampal synaptic transmission via a presynaptic PGE2 EP2 receptor","volume":"25","author":"Sang","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib23","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1515\/REVEH.2000.15.1-2.13","article-title":"Air pollution and health in urban areas","volume":"15","author":"Schwela","year":"2000","journal-title":"Rev. Environ. Health"},{"key":"10.1016\/j.ecoenv.2007.11.015_bib24","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0165-1110(77)90020-3","article-title":"Genetic effects of bisulfite (sulfur dioxide)","volume":"38","author":"Shapiro","year":"1977","journal-title":"Mutat. Res."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib25","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/0162-0134(94)85002-X","article-title":"Generation of SO3\u2212 and OH\u2212 radicals in SO32\u2212 reactions with inorganic environmental pollutants and its implications to SO32\u2212 toxicity","volume":"56","author":"Shi","year":"1994","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib26","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1006\/bbrc.1994.2641","article-title":"8-Hydroxy-2\u2032-deoxyguanosine formation and DNA damage induced by sulfur trioxide anion radicals","volume":"205","author":"Shi","year":"1994","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib27","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/S0031-6997(24)01469-8","article-title":"Potassium channels: molecular defects, diseases, and therapeutic opportunities","volume":"52","author":"Shieh","year":"2000","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib28","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1152\/jn.1992.68.1.55","article-title":"Patch-clamp study of postnatal development of CA1 neurons in rat hippocampal slices: membrane excitability and K+ current","volume":"68","author":"Spigelman","year":"1992","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib29","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0079-6123(08)61248-0","article-title":"Potassium currents in hippocampal pyramidal cells","volume":"83","author":"Storm","year":"1990","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib30","first-page":"55","article-title":"Formation of sulfate from l-cysteine in rat liver mitochondria","volume":"44","author":"Ubuka","year":"1990","journal-title":"Acta Med. Okayama"},{"key":"10.1016\/j.ecoenv.2007.11.015_bib31","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0006-8993(01)03242-5","article-title":"Troglitazone inhibits both post-glutamate neurotoxicity and low-potassium-induced apoptosis in cerebellar granule neurons","volume":"924","author":"Uryu","year":"2002","journal-title":"Brain Res."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib32","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.brainres.2003.11.036","article-title":"Effects of berberine on potassium currents in acutely isolated CA1 pyramidal neurons of rat hippocampus","volume":"999","author":"Wang","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib33","first-page":"524","article-title":"Effects of tetraethylammonium analogs on apoptosis and membrane currents in cultured cortical neurons","volume":"295","author":"Wang","year":"2000","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib34","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1161\/01.STR.0000065828.18661.FE","article-title":"Potassium channel blockers attenuate hypoxia- and ischemia-induced neuronal death in vitro and in vivo","volume":"34","author":"Wei","year":"2003","journal-title":"Stroke"},{"key":"10.1016\/j.ecoenv.2007.11.015_bib35","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1523\/JNEUROSCI.22-04-01350.2002","article-title":"Ionic mechanism of ouabain-induced concurrent apoptosis and necrosis in individual cultured cortical neurons","volume":"15","author":"Xiao","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib36","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1007\/s002449900552","article-title":"Age-related alterations in antioxidant enzymes, lipid peroxide levels, and somatosensory-evoked potentials: effect of sulfur dioxide","volume":"37","author":"Yargico\u011flu","year":"1999","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib37","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S0301-0082(03)00090-X","article-title":"Regulation and critical role of potassium homeostasis in apoptosis","volume":"70","author":"Yu","year":"2003","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib40","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1126\/science.278.5335.114","article-title":"Mediation of neuronal apoptosis by enhancement of outward potassium current","volume":"278","author":"Yu","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.ecoenv.2007.11.015_bib39","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1046\/j.1471-4159.1999.0730933.x","article-title":"Role of the outward delayed rectifier K+ current in ceramide-induced caspase activation and apoptosis in cultured cortical neurons","volume":"73","author":"Yu","year":"1999","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ecoenv.2007.11.015_bib38","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/S0955-0674(00)00228-3","article-title":"Ion homeostasis and apoptosis","volume":"13","author":"Yu","year":"2001","journal-title":"Curr. Opin. Cell Biol."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651307003119?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651307003119?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T18:11:08Z","timestamp":1738087868000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651307003119"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["S0147651307003119"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2007.11.015","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2009,1]]}}}