{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T14:20:50Z","timestamp":1779891650148,"version":"3.53.1"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003074","name":"Agencia Nacional de Promoci\u00f3n Cient\u00edfica y Tecnol\u00f3gica","doi-asserted-by":"publisher","award":["PICT 2011-1349"],"award-info":[{"award-number":["PICT 2011-1349"]}],"id":[{"id":"10.13039\/501100003074","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005746","name":"Universidad Nacional del Litoral","doi-asserted-by":"publisher","award":["CAID 2012-50120110100189"],"award-info":[{"award-number":["CAID 2012-50120110100189"]}],"id":[{"id":"10.13039\/501100005746","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.ecoenv.2018.06.006","type":"journal-article","created":{"date-parts":[[2018,6,14]],"date-time":"2018-06-14T02:26:05Z","timestamp":1528943165000},"page":"437-443","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"special_numbering":"C","title":["Oxidative damage and antioxidant defense in Caiman latirostris (Broad-snouted caiman) exposed in ovo to pesticide formulations"],"prefix":"10.1016","volume":"161","author":[{"given":"P.M.","family":"Burella","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.M.","family":"Odetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.F.","family":"Simoniello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.L.","family":"Poletta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2018.06.006_bib1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0076-6879(84)05016-3","article-title":"Catalase in vitro","volume":"105","author":"Aebi","year":"1984","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib2","doi-asserted-by":"crossref","first-page":"432","DOI":"10.3923\/jas.2003.432.445","article-title":"Toxic effects of cypermethrin on the biochemistry and morphology of 11th day chick embryo (Gallus domesticus)","author":"Anwar","year":"2003","journal-title":"Appl. Sci."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib3","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1016\/j.chemosphere.2013.06.041","article-title":"Environmental fate of glyphosate and aminomethylphosphonic acid in surface waters and soil of agricultural basins","volume":"93","author":"Aparicio","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2018.06.006_bib4","doi-asserted-by":"crossref","first-page":"e0130002","DOI":"10.1371\/journal.pone.0130002","article-title":"Biotransformation and oxidative stress responses in captive nile crocodile (Crocodylus niloticus) exposed to organic contaminants from the natural environment in South Africa","volume":"10","author":"Arukwe","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.ecoenv.2018.06.006_bib5","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.ecoenv.2006.12.018","article-title":"In ovum exposure to pesticides increases the egg weight loss and decreases hatchlings weight of Caiman latirostris (Crocodylia: alligatoridae)","volume":"68","author":"Beldomenico","year":"2007","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"52","key":"10.1016\/j.ecoenv.2018.06.006_bib6","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/S0076-6879(78)52032-6","article-title":"Microsomal lipid peroxidation","volume":"30","author":"Buege","year":"1978","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib7","unstructured":"CASAFE,\u00a02013. C\u00e1mara de Sanidad Agropecuaria y Fertilizantes Argentina. \u3008http:\/\/www.casafe.org\/\u3009 (March 2015)."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib8","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.mrrev.2007.10.002","article-title":"Investigating oxidative DNA damage and its repair using the comet assay","volume":"681","author":"Collins","year":"2009","journal-title":"Mutat. Res."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib9","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1096\/fj.02-0752rev","article-title":"Oxidative DNA damage: mechanisms, mutation, and disease","volume":"17","author":"Cooke","year":"2003","journal-title":"FASEB J."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib10","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.envpol.2017.05.035","article-title":"Pyrethroid insecticides in wild bird eggs from a World Heritage Listed Park: a case study in Do\u00f1ana National Park (Spain)","volume":"228","author":"Corcellas","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib11","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.chemosphere.2014.01.039","article-title":"Presence of pesticides in surface water from four sub-basins in Argentina","volume":"107","author":"De Ger\u00f3nimo","year":"2014","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2018.06.006_bib12","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.cbpa.2016.05.006","article-title":"Usefulness of oxidative stress biomarkers evaluated in the snout scraping, serum and Peripheral Blood Cells of Crocodylus moreletii from Southeast Campeche for assessment of the toxic impact of PAHs, metals and total phenols","volume":"200","author":"Dzul-Caamal","year":"2016","journal-title":"Comp. Biochem. Physiol. A"},{"key":"10.1016\/j.ecoenv.2018.06.006_bib13","unstructured":"EXTOXNET: The Extension Toxicology Network. Pesticide Information Profiles (PIPs) [Internet]; [access October 2016]. Available from: \/ \u3008http:\/\/extoxnet.orst.edu\/pips\/ghindex.html\u3009."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib14","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1753-4887.2012.00476.x","article-title":"Free radicals and antioxidants: updating a personal view","volume":"70","author":"Halliwell","year":"2012","journal-title":"Nutr. Rev."},{"issue":"12","key":"10.1016\/j.ecoenv.2018.06.006_bib15","doi-asserted-by":"crossref","first-page":"3343","DOI":"10.1002\/etc.3916","article-title":"Oxidative stress induced by glyphosate-based herbicide on freshwater turtles","volume":"36","author":"H\u00e9ritier","year":"2017","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib16","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.chemosphere.2017.05.116","article-title":"Oxidative stress biomarkers in the Mediterranean pond turtle (Mauremys leprosa) reveal contrasted aquatic environments in Southern France","volume":"183","author":"H\u00e9ritier","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2018.06.006_bib17","series-title":"Functional Metabolism: Regulation and Adaptation","first-page":"319","article-title":"Oxygen in biology and biochemistry: role of free radicals","author":"Hermes-Lima","year":"2004"},{"key":"10.1016\/j.ecoenv.2018.06.006_bib18","first-page":"29","article-title":"Oxidative stress in liver and brain of the hatchling chicken (Gallus domesticus) following in ovo injection with TCDD","volume":"136","author":"Hilscherova","year":"2003","journal-title":"Comp. Biochem. Physiol. C: Toxicol. Pharmacol."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib19","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1152\/physrev.00047.2006","article-title":"Life and death: metabolic rate, membrane composition, and life span of animals","volume":"87","author":"Hulbert","year":"2007","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib20","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.mrfmmm.2010.12.016","article-title":"Role of oxidative stress and DNA damage in human carcinogenesis","volume":"711","author":"Kryston","year":"2011","journal-title":"Mut. Res. Fund. Mol. Mech. Mut."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib21","unstructured":"Larriera, A., Imhof, A., Siroski, P., 2008. Estado actual de los programas de conservaci\u00f3n y manejo de g\u00e9nero Caiman en Argentina. In: Castroviejo, J., Ayarzaguena, J., Velasco, A. (Eds.), Contribuci\u00f3n al conocimiento del Genero Caiman de Suramerica, Public. Asoc. Amigos de Do\u00f1a Ana 18, Sevilla, Espa\u00f1a, pp. 139\u2013179."},{"issue":"6","key":"10.1016\/j.ecoenv.2018.06.006_bib22","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1080\/1547691X.2016.1236854","article-title":"Total and differential white blood cells count in Caiman latirostris after in ovo and in vivo exposure to insecticides","volume":"13","author":"Latorre","year":"2016","journal-title":"J. Immunotoxicol."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib23","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.mrgentox.2008.09.015","article-title":"The role of antioxidants and antioxidant-related enzymes in protective responses to environmentally induced oxidative stress","volume":"674","author":"Lim\u00f3n-Pacheco","year":"2009","journal-title":"Mutat. Res. Genet. Toxicol. Environ. Mutagen."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib24","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.ecoenv.2016.10.035","article-title":"Micronuclei and other nuclear abnormalities on Caiman latirostris (broad-snouted caiman) hatchlings after embryonic exposure to different pesticide formulations","volume":"136","author":"L\u00f3pez Gonz\u00e1lez","year":"2017","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib25","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1007\/s00128-005-0824-7","article-title":"Cypermethrin and chlorpyrifos concentration levels in surface water bodies of the Pampa Ondulada, Argentina","volume":"75","author":"Marino","year":"2005","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib26","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1461-0248.2008.01258.x","article-title":"Oxidative stress as a mediator of life history tradeoffs: mechanisms measurements and interpretation","volume":"12","author":"Monaghan","year":"2009","journal-title":"Ecol. Lett."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib27","first-page":"1","article-title":"The post-occipital spinal venous sinus of the Nile crocodile (Crocodylus niloticus): its anatomy and use for blood sample collection and intravenous infusions","volume":"82","author":"Myburgh","year":"2014","journal-title":"J. S. Afr. Vet. Assoc."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib28","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1016\/j.chemosphere.2017.06.109","article-title":"Pyrethroids in chicken eggs from commercial farms and home production in Rio de Janeiro: estimated daily intake and diastereomeric selectivity","volume":"184","author":"Parente","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2018.06.006_bib29","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.ecoenv.2017.04.054","article-title":"Evaluation of imazethapyr-induced DNA oxidative damage by alkaline Endo III- and Fpg-modified single-cell gel electrophoresis assay in Hypsiboas pulchellus tadpoles (Anura, Hylidae)","volume":"142","author":"P\u00e9rez-Iglesias","year":"2017","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib30","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.mrgentox.2007.12.001","article-title":"Caiman latirostris (Broad-snouted caiman) as a sentinel organism for genotoxic monitoring: basal values determination of micronucleus and comet assay","volume":"650","author":"Poletta","year":"2008","journal-title":"Mutat. Res."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib31","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.mrgentox.2008.10.007","article-title":"Genotoxicity of the herbicide formulation Roundup\u00ae (glyphosate) in broad-snouted caiman (Caiman latirostris) evidenced by the Comet assay and the Micronucleus test","volume":"672","author":"Poletta","year":"2009","journal-title":"Mutat. Res."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib32","first-page":"929","article-title":"Biomarkers of oxidative damage and antioxidant defense capacity in Caiman latirostris blood","volume":"17","author":"Poletta","year":"2016","journal-title":"Comp. Biochem Physiol. C: Toxicol. Pharmacol."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib33","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.envpol.2017.06.006","article-title":"Glyphosate and AMPA, \u201cpseudo-persistent\u201d pollutants under real world agricultural management practices in the Mesopotamic Pampas agroecosystem, Argentina","volume":"229","author":"Primost","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib34","first-page":"1","article-title":"Water and sediment quality assessment: impact of industry and agriculture on aquatic ecosystems in Santa Fe (Argentina)","author":"Regaldo","year":"2017","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib35","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.toxlet.2007.09.003","article-title":"Dietary exposure to diesel exhaust particles and oxidatively damaged DNA in young oxoguanine DNA glycosylase 1 deficient mice","volume":"175","author":"Risom","year":"2007","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib36","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1007\/s10661-016-5467-0","article-title":"Water quality of the main tributaries of the Parana\u00b4 Basin: glyphosate and AMPA in surface water and bottom sediments","volume":"188","author":"Ronco","year":"2016","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib37","unstructured":"S\u00f6dergren, E., 2000. Lipid peroxidation in vivo: Evaluation and application of methods for measurement. Acta Universitatis Upsaliensis.Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, 949, 78."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib38","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.ecoenv.2013.08.022","article-title":"The eggshell features and clutch viability of the broad-snouted caim\u00e1n (Caiman latirostris) are associated with the egg burden of organochlorine compounds","volume":"98","author":"Stoker","year":"2013","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2018.06.006_bib39","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1007\/s10646-017-1859-3","article-title":"Effects of Military activity and habitat quality on DNA damage and oxidative stress in the largest population of the Federally threatened gopher tortoise","volume":"26","author":"Theodorakis","year":"2017","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.ecoenv.2018.06.006_bib40","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1007\/s10695-015-0032-2","article-title":"Induction of DNA base damage and strand breaks in peripheral erythrocytes and the underlying mechanism in goldfish (Carassius auratus) exposed to monocrotophos","volume":"41","author":"Zhao","year":"2015","journal-title":"Fish. Physiol. Biochem."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651318304950?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651318304950?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T04:50:35Z","timestamp":1758948635000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651318304950"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":40,"alternative-id":["S0147651318304950"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2018.06.006","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oxidative damage and antioxidant defense in Caiman latirostris (Broad-snouted caiman) exposed in ovo to pesticide formulations","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2018.06.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}