{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T08:15:28Z","timestamp":1787904928650,"version":"build-2784847793"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["91643113"],"award-info":[{"award-number":["91643113"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21637004"],"award-info":[{"award-number":["21637004"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21405019"],"award-info":[{"award-number":["21405019"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"key project of natural science research of Anhui provincial education department","award":["KJ2016A873"],"award-info":[{"award-number":["KJ2016A873"]}]},{"name":"key project of natural science research of Anhui provincial education department","award":["20528110203"],"award-info":[{"award-number":["20528110203"]}]},{"name":"Anhui province colleges and Universities","award":["gxyqZD2016193"],"award-info":[{"award-number":["gxyqZD2016193"]}]},{"DOI":"10.13039\/501100012404","name":"Fuyang Normal University","doi-asserted-by":"crossref","award":["XDHX201701"],"award-info":[{"award-number":["XDHX201701"]}],"id":[{"id":"10.13039\/501100012404","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1016\/j.ecoenv.2018.09.040","type":"journal-article","created":{"date-parts":[[2018,9,13]],"date-time":"2018-09-13T14:36:12Z","timestamp":1536849372000},"page":"484-494","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"special_numbering":"C","title":["In vitro and in vivo toxic effects and inflammatory responses induced by carboxylated black carbon-lead complex exposure"],"prefix":"10.1016","volume":"165","author":[{"given":"Shuanglin","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengting","family":"Shang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kui","family":"Mu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyan","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenyong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2018.09.040_bib1","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1080\/10962247.2014.1001884","article-title":"Particulate matter components, sources, and health: systematic approaches to testing effects","volume":"65","author":"Adams","year":"2015","journal-title":"J. Air Waste Manag. Assoc."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib2","doi-asserted-by":"crossref","first-page":"13229","DOI":"10.1073\/pnas.1317176111","article-title":"Highway proximity and black carbon from cookstoves as a risk factor for higher blood pressure in rural China","volume":"111","author":"Baumgartner","year":"2014","journal-title":"PNAS"},{"key":"10.1016\/j.ecoenv.2018.09.040_bib3","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1007\/s12012-013-9223-1","article-title":"Carbon black nanoparticleintratracheal instillation does not alter cardiac gene expression","volume":"13","author":"Bourdon","year":"2013","journal-title":"Cardiovasc Toxicol."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib4","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/1743-8977-9-45","article-title":"Wood smoke particles from different combustion phases induce similar pro-inflammatory effects in a co-culture of monocyte and pneumocyte cell lines","volume":"9","author":"B\u00f8lling","year":"2012","journal-title":"Part. Fibre Toxicol."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib5","doi-asserted-by":"crossref","first-page":"2718","DOI":"10.1039\/c2cs15309b","article-title":"Endocytosis at the nanoscale","volume":"7","author":"Canton","year":"2012","journal-title":"Chem. Soc. Rev."},{"issue":"2","key":"10.1016\/j.ecoenv.2018.09.040_bib6","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1080\/10408444.2017.1391746","article-title":"Evaluating the evidence on genotoxicity and reproductive toxicity of carbon black: a critical review","volume":"48","author":"Chaudhuri","year":"2018","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib7","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.jes.2016.10.013","article-title":"Particulate matter (PM2.5) exposure season-dependently induces neuronal apoptosis and synaptic injuries","volume":"54","author":"Chen","year":"2017","journal-title":"J. Environ. Sci."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib8","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/nature01451","article-title":"Regulated portals of entry into the cell","volume":"422","author":"Conner","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.ecoenv.2018.09.040_bib9","doi-asserted-by":"crossref","first-page":"3197","DOI":"10.1007\/s00216-011-5102-4","article-title":"Anti-oxidative and inflammatory responses induced by fly ash particles and carbon black in lung epithelial cells","volume":"401","author":"Diabat\u00e9","year":"2011","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib10","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.envpol.2016.05.075","article-title":"Gas flaring and resultant air pollution: a review focusing on black carbon","volume":"216","author":"Fawole","year":"2016","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib11","doi-asserted-by":"crossref","first-page":"27767","DOI":"10.1007\/s11356-017-0228-3","article-title":"Low-dose combined exposure of nanoparticles and heavy metal compared with PM2.5 in human myocardial AC16 cells","volume":"24","author":"Feng","year":"2017","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib12","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1289\/ehp.11223","article-title":"Association between traffic-related black carbon exposure and lung function among urban women","volume":"116","author":"Franco Suglia","year":"2008","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib13","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s12989-017-0200-x","article-title":"Early pulmonary response is critical for extra-pulmonary carbon nanoparticle mediated effects: comparison of inhalation versus intra-arterial infusion exposures in mice","volume":"14","author":"Ganguly","year":"2017","journal-title":"Part Fibre Toxicol."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib14","first-page":"400","article-title":"Comparison of genetic damage in mice exposed to black carbon and ozone-oxidized black carbon","volume":"3","author":"Gao","year":"2014","journal-title":"J. Peking. Univ. (Health Sci.)"},{"key":"10.1016\/j.ecoenv.2018.09.040_bib15","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1093\/mutage\/gex042","article-title":"Influence of dispersion medium on nanomaterial-induced pulmonary inflammation and DNA strand breaks: investigation of carbon black, carbon nanotubes and three titanium dioxide nanoparticles","volume":"32","author":"Hadrup","year":"2017","journal-title":"Mutagenesis"},{"key":"10.1016\/j.ecoenv.2018.09.040_bib16","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1039\/C5TX00351B","article-title":"Fine particulate matter induces vascular endothelial activation via IL-6 dependent JAK1\/STAT3 signaling pathway","volume":"5","author":"Hu","year":"2016","journal-title":"Toxicol. Res."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib17","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.atmosenv.2017.06.036","article-title":"Trends in black carbon and size-resolved particle number concentrations and vehicle emission factors under real-world conditions","volume":"165","author":"Krecl","year":"2017","journal-title":"Atmos. Res."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib18","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/mutage\/gev009","article-title":"DNA strand breaks, acute phase response and inflammation following pulmonary exposure by instillation to the dieselexhaust particle NIST1650b in mice","volume":"4","author":"Kyjovska","year":"2015","journal-title":"Mutagenesis"},{"key":"10.1016\/j.ecoenv.2018.09.040_bib19","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.envpol.2013.06.009","article-title":"Carbon black vs. black carbon and other airborne materials containing elemental carbon: physical and chemical distinctions","volume":"181","author":"Long","year":"2013","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib20","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1007\/s00204-016-1837-1","article-title":"A gulatory network among LncRpa, CircRar1, MiR-671 and apoptotic genes promotes lead-induced neuronal cell apoptosis","volume":"9","author":"Nan","year":"2017","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib21","first-page":"20","article-title":"Pneumotoxicity and hematotoxicity of airborne fine particles and lead compounds on rats","volume":"1","author":"Qian","year":"2011","journal-title":"J. Environ. Occup. Med."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib22","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/s13273-011-0052-7","article-title":"Effects of carbon black to inflammation and oxidative DNA damages in mouse macrophages","volume":"7","author":"Rim","year":"2011","journal-title":"Mol. Cell Toxicol."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib23","doi-asserted-by":"crossref","first-page":"294","DOI":"10.3390\/su2010294","article-title":"Black carbon's properties and role in the environment: a comprehensive review","volume":"2","author":"Shrestha","year":"2010","journal-title":"Sustainability"},{"key":"10.1016\/j.ecoenv.2018.09.040_bib24","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s12989-017-0220-6","article-title":"In vitro toxicoproteomic analysis of A549 human lung epithelial cells exposed to urban air particulate matter and its water-soluble and insoluble fractions","volume":"14","author":"Vuong","year":"2017","journal-title":"Part Fibre Toxicol."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib25","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1172\/JCI112001","article-title":"Systemic complement activation, lung injury and products of liquid peroxidation","volume":"6","author":"Ward","year":"1985","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib26","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.ecoenv.2017.12.044","article-title":"Oxygen content determines the bio-reactivity and toxicity profiles of carbon black particles","volume":"150","author":"Wu","year":"2018","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2018.09.040_bib27","first-page":"690","article-title":"Effect of 1,4-naphthoquinone aged black carbon on reactive oxygen species and DNA strand breaks in human bronchial epithelial cells","volume":"4","author":"Zhang","year":"2015","journal-title":"J. Peking. Univ. (Health Sci.)"},{"key":"10.1016\/j.ecoenv.2018.09.040_bib28","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jqsrt.2014.03.006","article-title":"Black carbon aerosols in urban central China","volume":"150","author":"Zhang","year":"2015","journal-title":"J. Quant. Spectrosc. RA"},{"key":"10.1016\/j.ecoenv.2018.09.040_bib29","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.envpol.2016.05.072","article-title":"Heavy metals bound to fine particulate matter from northern China induce season-dependent health risks: a study based on myocardial toxicity","volume":"216","author":"Zhang","year":"2016","journal-title":"Environ. Pollut."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651318309011?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651318309011?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T23:17:41Z","timestamp":1589930261000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651318309011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":29,"alternative-id":["S0147651318309011"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2018.09.040","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In vitro and in vivo toxic effects and inflammatory responses induced by carboxylated black carbon-lead complex exposure","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2018.09.040","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}