{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T10:08:34Z","timestamp":1790762914239,"version":"4.1.0"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,11,20]],"date-time":"2020-11-20T00:00:00Z","timestamp":1605830400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"name":"NRF","award":["2016R1A2B4007714"],"award-info":[{"award-number":["2016R1A2B4007714"]}]},{"name":"NRF","award":["2019R1A2C1084556"],"award-info":[{"award-number":["2019R1A2C1084556"]}]},{"name":"Ministry of Education, Science and Technology, Korea"},{"name":"Environmental Health R&D Program","award":["H117-00137-0702"],"award-info":[{"award-number":["H117-00137-0702"]}]},{"name":"Ministry of Environment, Korea"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.ecoenv.2020.111263","type":"journal-article","created":{"date-parts":[[2020,9,9]],"date-time":"2020-09-09T03:52:09Z","timestamp":1599623529000},"page":"111263","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Effects of tris(2-chloroethyl) phosphate exposure on chicken embryos in a shell-less incubation system"],"prefix":"10.1016","volume":"207","author":[{"given":"Kazuki","family":"Kanda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shohei","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Hee","family":"Koh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun-Young","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisato","family":"Iwata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2020.111263_bib1","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.ntt.2018.10.002","article-title":"Toxicity profiling of flame retardants in zebrafish embryos using a battery of assays for developmental toxicity, neurotoxicity, cardiotoxicity and hepatotoxicity toward human relevance","volume":"70","author":"Alzualde","year":"2018","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.ecoenv.2020.111263_bib27","series-title":"The Atlas of Chick Development","author":"Bellairs","year":"2005"},{"key":"10.1016\/j.ecoenv.2020.111263_bib2","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.envpol.2013.04.001","article-title":"Occurrence and risk assessment of organophosphorus and brominated flame retardants in the River Aire (UK)","volume":"179","author":"Cristale","year":"2013","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2020.111263_bib3","doi-asserted-by":"crossref","first-page":"10820","DOI":"10.1021\/acs.est.8b03730","article-title":"Tris(1,3-dichloro-2-propyl) phosphate exposure during the early-blastula stage alters the normal trajectory of zebrafish embryogenesis","volume":"52","author":"Dasgupta","year":"2018","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ecoenv.2020.111263_bib4","doi-asserted-by":"crossref","first-page":"e4156","DOI":"10.7717\/peerj.4156","article-title":"Tris(1,3-dichloro-2-propyl) phosphate disrupts dorsoventral patterning in zebrafish embryos","volume":"5","author":"Dasgupta","year":"2017","journal-title":"PeerJ"},{"key":"10.1016\/j.ecoenv.2020.111263_bib5","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.aquatox.2015.01.027","article-title":"Aryl organophosphate flame retardants induced cardiotoxicity during zebrafish embryogenesis: by disturbing expression of the transcriptional regulators","volume":"161","author":"Du","year":"2015","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.ecoenv.2020.111263_bib6","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1093\/toxsci\/kft100","article-title":"In ovo effects of two organophosphate flame Retardants-TCPP and TDCPP-on pipping success, development, mRNA expression, and thyroid hormone levels in chicken embryos","volume":"134","author":"Farhat","year":"2013","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.ecoenv.2020.111263_bib7","doi-asserted-by":"crossref","first-page":"7942","DOI":"10.1021\/es501334w","article-title":"Comparative body compartment composition and in ovo transfer of organophosphate flame retardants in North American Great Lakes herring gulls","volume":"48","author":"Greaves","year":"2014","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ecoenv.2020.111263_bib8","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.taap.2018.03.026","article-title":"Effects of prenatal exposure to triclosan on the liver transcriptome in chicken embryos","volume":"347","author":"Guo","year":"2018","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.ecoenv.2020.111263_bib9","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.envpol.2018.02.056","article-title":"Accumulation of flame retardants in paired eggs and plasma of bald eagles","volume":"237","author":"Guo","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2020.111263_bib10","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1021\/es035082g","article-title":"Polybrominated diphenyl ethers in the environment and in people: a meta-analysis of concentrations","volume":"38","author":"Hites","year":"2004","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ecoenv.2020.111263_bib11","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.aquatox.2015.02.009","article-title":"Triphenyl phosphate-induced developmental toxicity in zebrafish\u00a0: potential role of the retinoic acid receptor","volume":"161","author":"Isales","year":"2015","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.ecoenv.2020.111263_bib12","doi-asserted-by":"crossref","first-page":"125738","DOI":"10.1016\/j.chemosphere.2019.125738","article-title":"Developmental circulatory failure caused by metabolites of organophosphorus flame retardants in zebrafish, Danio rerio","volume":"246","author":"Lee","year":"2020","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2020.111263_bib13","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1016\/S0045-6535(03)00666-0","article-title":"Screening of organophosphorus compounds and their distribution in various indoor environments","volume":"53","author":"Marklund","year":"2003","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2020.111263_bib14","doi-asserted-by":"crossref","first-page":"3425","DOI":"10.1016\/j.scitotenv.2009.01.030","article-title":"Polybrominated diphenyl ether (PBDE) concentrations in house dust are related to hormone levels in men","volume":"407","author":"Meeker","year":"2009","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2020.111263_bib15","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1046\/j.1440-169x.1999.00454.x","article-title":"Development of the skeleton in Japanese quail embryos","volume":"41","author":"Nakane","year":"1999","journal-title":"Dev. Growth Differ."},{"key":"10.1016\/j.ecoenv.2020.111263_bib16","series-title":"Avian Acute Oral Toxicity Test. Test Guideline No. 223. Guideline for the Testing of Chemicals 1\u201315","year":"2016"},{"key":"10.1016\/j.ecoenv.2020.111263_bib17","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/331070a0","article-title":"A complete culture system for the chick embryo","volume":"331","author":"Perry","year":"1988","journal-title":"Nature"},{"key":"10.1016\/j.ecoenv.2020.111263_bib18","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.trac.2008.07.002","article-title":"Organophosphorus flame retardants and plasticizers in water and air I. Occurrence and fate","volume":"27","author":"Reemtsma","year":"2008","journal-title":"TrAC Trends Anal. Chem. (Reference Ed.)"},{"key":"10.1016\/j.ecoenv.2020.111263_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/inventions3020021","article-title":"A simple ImageJ-based method to measure cardiac rhythm in zebrafish embryos","volume":"3","author":"Sampurna","year":"2018","journal-title":"Inventions"},{"key":"10.1016\/j.ecoenv.2020.111263_bib20","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.jsbmb.2011.08.007","article-title":"Endocrine disrupting chemicals and disease susceptibility","volume":"127","author":"Schug","year":"2011","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.ecoenv.2020.111263_bib21","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.taap.2017.02.020","article-title":"In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model","volume":"322","author":"Sirenko","year":"2017","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.ecoenv.2020.111263_bib22","doi-asserted-by":"crossref","first-page":"307","DOI":"10.2141\/jpsa.0130043","article-title":"A novel shell-less culture system for chick embryos using a plastic film as culture vessels","volume":"51","author":"Tahara","year":"2014","journal-title":"Japan Poult. Sci. Assoc."},{"key":"10.1016\/j.ecoenv.2020.111263_bib23","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/j.scitotenv.2018.05.222","article-title":"Science of the Total Environment Unusually high Deca-BDE concentrations and new fl ame retardants in a Canadian Arctic top predator , the glaucous gull","volume":"639","author":"Verreault","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2020.111263_bib24","doi-asserted-by":"crossref","first-page":"6705","DOI":"10.1016\/j.chroma.2011.07.067","article-title":"Development of an ultra-high-performance liquid chromatography\u2013tandem mass spectrometry method for high throughput determination of organophosphorus flame retardants in environmental water","volume":"1218","author":"Wang","year":"2011","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.ecoenv.2020.111263_bib25","first-page":"129","article-title":"Flame Retardants: tris (chloropropyl) phosphate and tris (2-chloroethyl) phosphate","volume":"209","author":"WHO","year":"1998","journal-title":"Environ. Health Criter."},{"key":"10.1016\/j.ecoenv.2020.111263_bib26","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.chemosphere.2016.10.038","article-title":"The combination of in silico and in vivo approaches for the investigation of disrupting effects of tris (2-chloroethyl) phosphate (TCEP) toward core receptors of zebrafish","volume":"168","author":"Wu","year":"2017","journal-title":"Chemosphere"}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651320311015?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651320311015?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T05:22:13Z","timestamp":1758950533000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651320311015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":27,"alternative-id":["S0147651320311015"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2020.111263","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of tris(2-chloroethyl) phosphate exposure on chicken embryos in a shell-less incubation system","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2020.111263","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"111263"}}