{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T07:58:34Z","timestamp":1793087914422,"version":"4.5.0"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,10,16]],"date-time":"2021-10-16T00:00:00Z","timestamp":1634342400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.ecoenv.2021.112916","type":"journal-article","created":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T08:43:54Z","timestamp":1635151434000},"page":"112916","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"special_numbering":"C","title":["Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse"],"prefix":"10.1016","volume":"227","author":[{"given":"Huiduo","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunnan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Qiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianwen","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weijiang","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2021.112916_bib1","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1272\/jnms.71.360","article-title":"Fetal and neonatal thermoregulation","volume":"71","author":"Asakura","year":"2004","journal-title":"J. Nippon Med. Sch."},{"key":"10.1016\/j.ecoenv.2021.112916_bib2","first-page":"200","article-title":"Elevated outdoor temperatures and risk of stillbirth","volume":"46","author":"Auger","year":"2017","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.ecoenv.2021.112916_bib3","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1111\/jpn.12379","article-title":"Heat stress effects on livestock: molecular, cellular and metabolic aspects, a review","volume":"100","author":"Belhadj Slimen","year":"2016","journal-title":"J. Anim. Physiol. Anim. Nutr."},{"key":"10.1016\/j.ecoenv.2021.112916_bib4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0110859","article-title":"Gestational heat stress alters postnatal offspring body composition indices and metabolic parameters in pigs","volume":"9","author":"Boddicker","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.ecoenv.2021.112916_bib5","doi-asserted-by":"crossref","first-page":"15237","DOI":"10.1073\/pnas.1106022108","article-title":"Placental protection of the fetal brain during short-term food deprivation","volume":"108","author":"Broad","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ecoenv.2021.112916_bib6","doi-asserted-by":"crossref","first-page":"S23","DOI":"10.1016\/j.placenta.2011.11.013","article-title":"Review: The placenta and developmental programming: Balancing fetal nutrient demands with maternal resource allocation","volume":"33","author":"Burton","year":"2012","journal-title":"Placenta"},{"key":"10.1016\/j.ecoenv.2021.112916_bib7","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.brainresrev.2010.06.002","article-title":"Prenatal stress and brain development","volume":"65","author":"Charil","year":"2010","journal-title":"Brain Res. Rev."},{"key":"10.1016\/j.ecoenv.2021.112916_bib8","doi-asserted-by":"crossref","first-page":"2469","DOI":"10.1113\/JP279398","article-title":"Placental fatty acid transport across late gestation in a baboon model of intrauterine growth restriction","volume":"598","author":"Chassen","year":"2020","journal-title":"J. Physiol."},{"key":"10.1016\/j.ecoenv.2021.112916_bib9","doi-asserted-by":"crossref","first-page":"309","DOI":"10.2527\/jas1982.542309x","article-title":"Effects of heat stress during pregnancy on maternal hormone concentrations, calf birth weight and postpartum milk yield of Holstein cows","volume":"54","author":"Collier","year":"1982","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.ecoenv.2021.112916_bib10","series-title":"Anatomy, Abdomen and Pelvis, Small Intestine","author":"Collins","year":"2021"},{"key":"10.1016\/j.ecoenv.2021.112916_bib11","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.rbmo.2015.10.005","article-title":"The endocrine function of human placenta: an overview","volume":"32","author":"Costa","year":"2016","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.ecoenv.2021.112916_bib12","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.placenta.2020.05.004","article-title":"Maternal stress in relation to sex-specific expression of placental genes involved in nutrient transport, oxygen tension, immune response, and the glucocorticoid barrier","volume":"96","author":"Cowell","year":"2020","journal-title":"Placenta"},{"key":"10.1016\/j.ecoenv.2021.112916_bib13","doi-asserted-by":"crossref","first-page":"5500","DOI":"10.1210\/en.2012-1479","article-title":"Maternal corticosterone exposure in the mouse has sex-specific effects on placental growth and mRNA expression","volume":"153","author":"Cuffe","year":"2012","journal-title":"Endocrinology"},{"key":"10.1016\/j.ecoenv.2021.112916_bib14","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1113\/jphysiol.2014.272856","article-title":"Mid-to late term hypoxia in the mouse alters placental morphology, glucocorticoid regulatory pathways and nutrient transporters in a sex-specific manner","volume":"592","author":"Cuffe","year":"2014","journal-title":"J. Physiol."},{"key":"10.1016\/j.ecoenv.2021.112916_bib15","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.theriogenology.2020.05.012","article-title":"Carry over effects of late-gestational heat stress on dairy cattle progeny","volume":"154","author":"Dado-Senn","year":"2020","journal-title":"Theriogenology"},{"key":"10.1016\/j.ecoenv.2021.112916_bib16","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1369\/0022155414532655","article-title":"Intrauterine growth restriction impairs small intestinal mucosal immunity in neonatal piglets","volume":"62","author":"Dong","year":"2014","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.ecoenv.2021.112916_bib17","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/evj.13206","article-title":"Physiological development of the equine fetus during late gestation","volume":"52","author":"Fowden","year":"2020","journal-title":"Equine Vet. J."},{"key":"10.1016\/j.ecoenv.2021.112916_bib18","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.placenta.2016.12.005","article-title":"Review: the blood-brain barrier; protecting the developing fetal brain","volume":"54","author":"Goasdou\u00e9","year":"2017","journal-title":"Placenta"},{"key":"10.1016\/j.ecoenv.2021.112916_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtherbio.2020.102539","article-title":"Responses of intestinal morphology and function in offspring to heat stress in primiparous sows during late gestation","volume":"89","author":"Guo","year":"2020","journal-title":"J. Therm. Biol."},{"key":"10.1016\/j.ecoenv.2021.112916_bib20","doi-asserted-by":"crossref","first-page":"3341","DOI":"10.1098\/rstb.2009.0131","article-title":"Effects of heat stress on mammalian reproduction","volume":"364","author":"Hansen","year":"2009","journal-title":"Philos. Trans. R. Soc. B-Biol. Sci."},{"key":"10.1016\/j.ecoenv.2021.112916_bib21","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.1111\/1751-7915.13893","article-title":"High ambient temperature exposure during late gestation disrupts glycolipid metabolism and hepatic mitochondrial function tightly related to gut microbial dysbiosis in pregnant mice","volume":"14","author":"He","year":"2021","journal-title":"Microb. Biotechnol."},{"key":"10.1016\/j.ecoenv.2021.112916_bib22","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jtherbio.2019.01.011","article-title":"A controlled heat stress during late gestation affects thermoregulation, productive performance, and metabolite profiles of primiparous sow","volume":"81","author":"He","year":"2019","journal-title":"J. Therm. Biol."},{"key":"10.1016\/j.ecoenv.2021.112916_bib23","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1385\/ENDO:19:1:43","article-title":"Lipid metabolism in pregnancy and its consequences in the fetus and newborn","volume":"19","author":"Herrera","year":"2002","journal-title":"Endocrine"},{"issue":"Suppl 3","key":"10.1016\/j.ecoenv.2021.112916_bib24","first-page":"59","article-title":"Maternal lipid metabolism and placental lipid transfer","volume":"65","author":"Herrera","year":"2006","journal-title":"Horm. Res."},{"key":"10.1016\/j.ecoenv.2021.112916_bib25","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.placenta.2020.12.008","article-title":"Maternal stress, placental 11\u03b2-hydroxysteroid dehydrogenase type 2, and infant HPA axis development in humans: psychosocial and physiological pathways","volume":"104","author":"Jahnke","year":"2021","journal-title":"Placenta"},{"key":"10.1016\/j.ecoenv.2021.112916_bib26","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1038\/s41593-018-0182-5","article-title":"The maternal vaginal microbiome partially mediates the effects of prenatal stress on offspring gut and hypothalamus","volume":"21","author":"Ja\u0161arevi\u0107","year":"2018","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.ecoenv.2021.112916_bib27","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jtherbio.2015.10.002","article-title":"The impact of in utero heat stress and nutrient restriction on progeny body composition","volume":"53","author":"Johnson","year":"2015","journal-title":"J. Therm. Biol."},{"key":"10.1016\/j.ecoenv.2021.112916_bib28","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1093\/jas\/sky472","article-title":"PHYSIOLOGY SYMPOSIUM: postnatal consequences of in utero heat stress in pigs","volume":"97","author":"Johnson","year":"2019","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.ecoenv.2021.112916_bib29","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.theriogenology.2020.05.013","article-title":"In utero heat stress alters postnatal phenotypes in swine","volume":"154","author":"Johnson","year":"2020","journal-title":"Theriogenology"},{"key":"10.1016\/j.ecoenv.2021.112916_bib30","doi-asserted-by":"crossref","first-page":"2976","DOI":"10.3168\/jds.2016-11993","article-title":"In utero exposure to heat stress during late gestation has prolonged effects on the activity patterns and growth of dairy calves","volume":"100","author":"Laporta","year":"2017","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.ecoenv.2021.112916_bib31","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1002\/(SICI)1097-0029(20000515)49:4<363::AID-JEMT5>3.0.CO;2-2","article-title":"Developmental aspects of lipid and lipoprotein synthesis and secretion in human gut","volume":"49","author":"Levy","year":"2000","journal-title":"Microsc. Res Tech."},{"key":"10.1016\/j.ecoenv.2021.112916_bib32","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/0014-5793(96)00896-4","article-title":"Insulin modulation of newly synthesized apolipoproteins B-100 and B-48 in human fetal intestine: gene expression and mRNA editing are not involved","volume":"393","author":"Levy","year":"1996","journal-title":"FEBS Lett."},{"key":"10.1016\/j.ecoenv.2021.112916_bib33","first-page":"6","article-title":"Deficiency of TRPM2 leads to embryonic neurogenesis defects in hyperthermia","volume":"6","author":"Li","year":"2020","journal-title":"Sci. Adv."},{"key":"10.1016\/j.ecoenv.2021.112916_bib34","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.3168\/jds.2008-1603","article-title":"Calf birth weight and its association with calf and cow survivability, disease incidence, reproductive performance, and milk production","volume":"92","author":"Linden","year":"2009","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.ecoenv.2021.112916_bib35","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.ecoenv.2021.112916_bib36","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1002\/mrd.22844","article-title":"Heat stress in pregnant sows: thermal responses and subsequent performance of sows and their offspring","volume":"84","author":"Lucy","year":"2017","journal-title":"Mol. Reprod. Dev."},{"key":"10.1016\/j.ecoenv.2021.112916_bib37","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1017\/S0021932098000856","article-title":"An ecologic study of the relationship between mean birth weight, temperature and calorie consumption level in Japan","volume":"30","author":"Matsuda","year":"1998","journal-title":"J. Biosoc. Sci."},{"key":"10.1016\/j.ecoenv.2021.112916_bib38","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.placenta.2017.06.343","article-title":"Temporal and spatial expression of glyceraldehyde 3-phosphate dehydrogenase (Gapdh) in the mouse placenta","volume":"57","author":"Min","year":"2017","journal-title":"Placenta"},{"key":"10.1016\/j.ecoenv.2021.112916_bib39","doi-asserted-by":"crossref","first-page":"3896","DOI":"10.3168\/jds.2015-10699","article-title":"Effect of maternal heat stress during the dry period on growth and metabolism of calves","volume":"99","author":"Monteiro","year":"2016","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.ecoenv.2021.112916_bib40","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1159\/000488106","article-title":"The hypothalamic-pituitary-adrenal axis and the fetus","volume":"89","author":"Morsi","year":"2018","journal-title":"Horm. Res Paediatr."},{"key":"10.1016\/j.ecoenv.2021.112916_bib41","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1152\/physrev.2000.80.4.1633","article-title":"Development of intestinal transport function in mammals","volume":"80","author":"Pacha","year":"2000","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.ecoenv.2021.112916_bib42","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1080\/02656730410001716614","article-title":"Histological, histochemical and electron microscopic changes of the placenta induced by maternal exposure to hyperthermia in the rat","volume":"21","author":"Padmanabhan","year":"2005","journal-title":"Int. J. Hyperth."},{"key":"10.1016\/j.ecoenv.2021.112916_bib43","doi-asserted-by":"crossref","first-page":"G713","DOI":"10.1152\/ajpgi.1997.273.3.G713","article-title":"Ontogeny of intestinal adaptation in rats in response to isocaloric changes in dietary lipids","volume":"273","author":"Perin","year":"1997","journal-title":"Am. J. Physiol.-Gastrointest. Liver Physiol."},{"key":"10.1016\/j.ecoenv.2021.112916_bib44","doi-asserted-by":"crossref","first-page":"3795","DOI":"10.1093\/jas\/skz205","article-title":"Small intestinal transcriptome analysis revealed changes of genes involved in nutrition metabolism and immune responses in growth retardation piglets1","volume":"97","author":"Qi","year":"2019","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.ecoenv.2021.112916_bib45","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1113\/jphysiol.2005.104430","article-title":"Evidence for altered placental blood flow and vascularity in compromised pregnancies","volume":"572","author":"Reynolds","year":"2006","journal-title":"J. Physiol."},{"key":"10.1016\/j.ecoenv.2021.112916_bib46","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1097\/00007611-197610000-00031","article-title":"Placental transport of nutrients","volume":"69","author":"Robertson","year":"1976","journal-title":"South Med. J."},{"key":"10.1016\/j.ecoenv.2021.112916_bib47","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.3168\/jds.2020-19115","article-title":"Effects of late-gestation heat stress independent of reduced feed intake on colostrum, metabolism at calving, and milk yield in early lactation of dairy cows","volume":"104","author":"Seyed Almoosavi","year":"2021","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.ecoenv.2021.112916_bib48","doi-asserted-by":"crossref","first-page":"4970","DOI":"10.3168\/jds.2020-18301","article-title":"Heat stress affects the expression of key genes in the placenta, placental characteristics, and efficiency of Saanen goats and the survival and growth of their kids","volume":"104","author":"Silva","year":"2021","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.ecoenv.2021.112916_bib49","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1194\/jlr.M017418","article-title":"Impact of murine intestinal apolipoprotein A-IV expression on regional lipid absorption, gene expression, and growth","volume":"52","author":"Simon","year":"2011","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.ecoenv.2021.112916_bib50","doi-asserted-by":"crossref","first-page":"S66","DOI":"10.1016\/j.placenta.2015.11.013","article-title":"Effects of prenatal maternal stress on serotonin and fetal development","volume":"48","author":"St-Pierre","year":"2016","journal-title":"Placenta"},{"key":"10.1016\/j.ecoenv.2021.112916_bib51","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1093\/jas\/skz061","article-title":"PHYSIOLOGY SYMPOSIUM: effects of heat stress during late gestation on the dam and its calf12","volume":"97","author":"Tao","year":"2019","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.ecoenv.2021.112916_bib52","doi-asserted-by":"crossref","first-page":"7128","DOI":"10.3168\/jds.2012-5697","article-title":"Effect of late-gestation maternal heat stress on growth and immune function of dairy calves","volume":"95","author":"Tao","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.ecoenv.2021.112916_bib53","doi-asserted-by":"crossref","first-page":"168","DOI":"10.2527\/jas.2012-5730","article-title":"Environmental regulation of pregnancy-specific protein B concentrations during late pregnancy in dairy cattle","volume":"91","author":"Thompson","year":"2013","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.ecoenv.2021.112916_bib54","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/j.2042-3306.1997.tb05077.x","article-title":"Systemic and luminal influences on the perinatal development of the gut","author":"Trahair","year":"1997","journal-title":"Equine Vet. J. Suppl."},{"key":"10.1016\/j.ecoenv.2021.112916_bib55","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1038\/nbt.1621","article-title":"Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation","volume":"28","author":"Trapnell","year":"2010","journal-title":"Nat. Biotechnol."},{"issue":"Suppl 2","key":"10.1016\/j.ecoenv.2021.112916_bib56","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/rda.12797","article-title":"Placental metabolism: substrate requirements and the response to stress","volume":"51","author":"Vaughan","year":"2016","journal-title":"Reprod. Domest. Anim."},{"key":"10.1016\/j.ecoenv.2021.112916_bib57","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1111\/asj.12569","article-title":"Effects of temperature and temperature-humidity index on the reproductive performance of sows during summer months under a temperate climate","volume":"87","author":"Wegner","year":"2016","journal-title":"Anim. Sci. J."},{"key":"10.1016\/j.ecoenv.2021.112916_bib58","first-page":"223","article-title":"Comparative aspects of placental efficiency","volume":"58","author":"Wilson","year":"2001","journal-title":"Reprod. Suppl."},{"key":"10.1016\/j.ecoenv.2021.112916_bib59","doi-asserted-by":"crossref","unstructured":"Zeltser, L.M., Leibel, R.L., 2011. Roles of the placenta in fetal brain development. Proc. Natl. Acad. Sci. USA. 108, 15667\u201315668.","DOI":"10.1073\/pnas.1112239108"},{"key":"10.1016\/j.ecoenv.2021.112916_bib60","first-page":"22","article-title":"Maternal heat stress alters expression of genes associated with nutrient transport activity and metabolism in female placentae from mid-gestating pigs","volume":"22","author":"Zhao","year":"2021","journal-title":"Int. J. Mol. Sci."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651321010289?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651321010289?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T05:44:24Z","timestamp":1758951864000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651321010289"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":60,"alternative-id":["S0147651321010289"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2021.112916","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2021.112916","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"112916"}}