{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T16:33:38Z","timestamp":1775061218762,"version":"3.50.1"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,6]],"date-time":"2022-10-06T00:00:00Z","timestamp":1665014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.ecoenv.2022.114163","type":"journal-article","created":{"date-parts":[[2022,10,11]],"date-time":"2022-10-11T19:36:46Z","timestamp":1665517006000},"page":"114163","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Flurochloridone induced abnormal spermatogenesis by damaging testicular Sertoli cells in mice"],"prefix":"10.1016","volume":"246","author":[{"given":"Weiqi","family":"Sun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Tian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongjie","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuli","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minjie","family":"Xia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingying","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuzhu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Runsheng","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weihua","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingjun","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhijun","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2022.114163_bib1","first-page":"922","article-title":"Genomic Instability in Mice Lacking Histone H2AX","volume":"296","author":"Celeste","year":"2002","journal-title":"Science (American Association for the Advancement of Science)"},{"key":"10.1016\/j.ecoenv.2022.114163_bib2","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1038\/nrendo.2010.71","article-title":"A local autocrine axis in the testes that regulates spermatogenesis","volume":"6","author":"Cheng","year":"2010","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.ecoenv.2022.114163_bib3","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1124\/pr.110.002790","article-title":"The blood-testis barrier and its implications for male contraception","volume":"64","author":"Cheng","year":"2012","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.ecoenv.2022.114163_bib4","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.envpol.2012.09.002","article-title":"The ecological effects of a herbicide\u2013insecticide mixture on an experimental freshwater ecosystem","volume":"172","author":"Choung","year":"2013","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2022.114163_bib5","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1003787","article-title":"Meiotic recombination in Arabidopsis is catalysed by DMC1, with RAD51 playing a supporting role","volume":"9","author":"Da Ines","year":"2013","journal-title":"PLoS Genet."},{"key":"10.1016\/j.ecoenv.2022.114163_bib6","doi-asserted-by":"crossref","first-page":"3333","DOI":"10.1590\/1413-812320172210.17112017","article-title":"Use of genetically modified crops and pesticides in Brazil: growing hazards","volume":"22","author":"De Almeida","year":"2017","journal-title":"Ci\u00eanc Sa\u00fade Coletiva"},{"key":"10.1016\/j.ecoenv.2022.114163_bib7","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.1365-2613.2009.00692.x","article-title":"Testis response to low doses of cadmium in Wistar rats","volume":"91","author":"De Souza Predes","year":"2010","journal-title":"Int. J. Exp. Pathol."},{"key":"10.1016\/j.ecoenv.2022.114163_bib8","first-page":"53","article-title":"Causes and consequences of sperm mitochondrial dysfunction","author":"Durairajanayagam","year":"2021","journal-title":"ANDROLOGIA"},{"key":"10.1016\/j.ecoenv.2022.114163_bib9","article-title":"Review of the existing maximum residue levels for flurochloridone according to Article 12 of Regulation (EC) No 396\/2005","volume":"16","year":"2018","journal-title":"EFSA J."},{"key":"10.1016\/j.ecoenv.2022.114163_bib10","first-page":"3116","article-title":"Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance flurochloridone","volume":"11","year":"2013","journal-title":"EFSA J."},{"key":"10.1016\/j.ecoenv.2022.114163_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.acthis.2021.151822","article-title":"Different fixatives influence morphology, antigen preservation, and TUNEL staining in chicken (Gallus gallus) testis","volume":"123","author":"Feng","year":"2021","journal-title":"Acta Histochem."},{"key":"10.1016\/j.ecoenv.2022.114163_bib12","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S1534-5807(03)00093-5","article-title":"H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis","volume":"4","author":"Fernandez-Capetillo","year":"2003","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ecoenv.2022.114163_bib13","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1517\/14728222.2015.1039513","article-title":"Sertoli cells are the target of environmental toxicants in the testis \u2013 a mechanistic and therapeutic insight","volume":"19","author":"Gao","year":"2015","journal-title":"Expert Opin. Therapeutic Targets"},{"key":"10.1016\/j.ecoenv.2022.114163_bib14","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1096\/fj.201600870R","article-title":"Regulation of the blood-testis barrier by a local axis in the testis: role of laminin alpha2 in the basement membrane","volume":"31","author":"Gao","year":"2017","journal-title":"FASEB J."},{"key":"10.1016\/j.ecoenv.2022.114163_bib15","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1095\/biolreprod.110.088989","article-title":"Classification of mouse sperm motility patterns using an automated multiclass support vector machines Model1","volume":"84","author":"Goodson","year":"2011","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.ecoenv.2022.114163_bib16","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1146\/annurev-genet-120215-035111","article-title":"Control of meiotic crossovers: from double-strand break formation to designation","volume":"50","author":"Gray","year":"2016","journal-title":"Annu. Rev. Genet."},{"key":"10.1016\/j.ecoenv.2022.114163_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/physrev.00013.2015","article-title":"Spermatogenesis: the commitment to meiosis","volume":"96","author":"Griswold","year":"2016","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.ecoenv.2022.114163_bib18","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.stem.2014.01.019","article-title":"Mouse spermatogenic stem cells continually interconvert between equipotent singly isolated and syncytial states","volume":"14","author":"Hara","year":"2014","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.ecoenv.2022.114163_bib19","doi-asserted-by":"crossref","first-page":"745","DOI":"10.3390\/cells9030745","article-title":"Spermatogonial stem cells for in vitro spermatogenesis and in vivo restoration of fertility","volume":"9","author":"Ibtisham","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.ecoenv.2022.114163_bib20","first-page":"8","article-title":"Exposure of environmental Bisphenol A in relation to routine sperm parameters and sperm movement characteristics among fertile men","author":"Ji","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ecoenv.2022.114163_bib21","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.scitotenv.2016.09.009","article-title":"Exposure to pesticides and the associated human health effects","volume":"575","author":"Kim","year":"2017","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2022.114163_bib22","doi-asserted-by":"crossref","first-page":"5678","DOI":"10.1093\/nar\/gkn550","article-title":"-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin","volume":"36","author":"Kinner","year":"2008","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ecoenv.2022.114163_bib23","first-page":"255","article-title":"The effect of fluridone and flurochloridone on the incidence of albinism in pea (Pisum sativum) and on the abscission of leaves of privet (Ligustrum vulgare)","volume":"48","author":"Klicova","year":"2002","journal-title":"Rostl. Vyrob. - UZPI (Czech Repub. )"},{"key":"10.1016\/j.ecoenv.2022.114163_bib24","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1242\/jcs.02362","article-title":"SYCP2 and SYCP3 are required for cohesin core integrity at diplotene but not for centromere cohesion at the first meiotic division","volume":"118","author":"Kouznetsova","year":"2005","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.ecoenv.2022.114163_bib25","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.mce.2010.12.019","article-title":"GATA4 regulates Sertoli cell function and fertility in adult male mice\u2606","volume":"333","author":"Kyr\u00f6nlahti","year":"2011","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.ecoenv.2022.114163_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2605.2004.00505.x","article-title":"Expression and possible functions of DNA lesion bypass proteins in spermatogenesis","volume":"28","author":"Laan","year":"2005","journal-title":"Int. J. Androl."},{"key":"10.1016\/j.ecoenv.2022.114163_bib27","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.toxlet.2018.07.001","article-title":"Fluorochloridone perturbs blood-testis barrier\/Sertoli cell barrier function through Arp3-mediated F-actin disruption","volume":"295","author":"Liu","year":"2018","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.ecoenv.2022.114163_bib28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1004005","article-title":"Down-regulation of Rad51 activity during meiosis in yeast prevents competition with Dmc1 for repair of double-strand breaks","volume":"10","author":"Liu","year":"2014","journal-title":"PLoS Genet."},{"key":"10.1016\/j.ecoenv.2022.114163_bib29","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1038\/sj.cdd.4401046","article-title":"Inhibition of sperm production in mice by annexin V microinjected into seminiferous tubules: possible etiology of phagocytic clearance of apoptotic spermatogenic cells and male infertility","volume":"9","author":"Maeda","year":"2002","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.ecoenv.2022.114163_bib30","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/j.dnarep.2006.03.011","article-title":"Identification of a novel motif in DNA ligases exemplified by DNA ligase IV","volume":"5","author":"Marchetti","year":"2006","journal-title":"DNA Repair"},{"key":"10.1016\/j.ecoenv.2022.114163_bib31","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1126\/science.287.5457.1489","article-title":"Regulation of cell fate decision of undifferentiated spermatogonia by GDNF","volume":"287","author":"Meng","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.ecoenv.2022.114163_bib32","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.1365-3180.1996.tb01798.x","article-title":"Movement and persistence of imazaquin, oxyfluorfen, flurochloridone and terbacil in soil","volume":"36","author":"Milanova","year":"2010","journal-title":"WEED Res."},{"key":"10.1016\/j.ecoenv.2022.114163_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.112183","article-title":"Flurochloridone induces Sertoli cell apoptosis through ROS-dependent mitochondrial pathway","volume":"216","author":"Sun","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2022.114163_bib34","series-title":"WHO Laboratory Manual for the Examination and Processing of Human Semen","year":"2010"},{"key":"10.1016\/j.ecoenv.2022.114163_bib35","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/2190-4715-24-24","article-title":"Impacts of genetically engineered crops on pesticide use in the U.S. -- the first sixteen years","volume":"24","author":"Benbrook","year":"2012","journal-title":"Environ. ences Eur."},{"key":"10.1016\/j.ecoenv.2022.114163_bib36","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.ydbio.2014.10.020","article-title":"Retinoic acid regulates Kit translation during spermatogonial differentiation in the mouse","volume":"397","author":"Busada","year":"2015","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ecoenv.2022.114163_bib37","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1093\/mutage\/ger038","article-title":"Gamma-irradiation increased meiotic crossovers in mouse spermatocytes","volume":"26","author":"Cai","year":"2011","journal-title":"Mutagenesis"},{"key":"10.1016\/j.ecoenv.2022.114163_bib38","first-page":"6","article-title":"Disruption of dmc1 Produces Abnormal Sperm in Medaka (Oryzias latipes)","author":"Chen","year":"2016","journal-title":"SCI REP-UK"},{"key":"10.1016\/j.ecoenv.2022.114163_bib39","doi-asserted-by":"crossref","first-page":"R159","DOI":"10.1530\/REP-14-0481","article-title":"Regulation of spermatogonial stem cell self-renewal and spermatocyte meiosis by Sertoli cell signaling","volume":"149","author":"Chen","year":"2015","journal-title":"Reproduction"},{"key":"10.1016\/j.ecoenv.2022.114163_bib40","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1002\/jat.2886","article-title":"Nonylphenol-induced apoptotic cell death in mouse TM4 Sertoli cells via the generation of reactive oxygen species and activation of the ERK signaling pathway","volume":"34","author":"Choi","year":"2014","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.ecoenv.2022.114163_bib41","first-page":"8","article-title":"Conclusion on the peer review of the pesticide risk assessment of the active substance Flurochloridone (notified active substance)","author":"EFSA","year":"2010","journal-title":"EFSA J."},{"key":"10.1016\/j.ecoenv.2022.114163_bib42","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1002\/mrd.20278","article-title":"In vivo analysis of phagocytosis of apoptotic cells by testicular Sertoli cells","volume":"71","author":"Nakagawa","year":"2005","journal-title":"Mol. Reprod. Dev."},{"key":"10.1016\/j.ecoenv.2022.114163_bib43","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1002\/ijc.26445","article-title":"Repair of DNA damage induced by accelerated heavy ions-A mini review","volume":"130","author":"Okayasu","year":"2012","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.ecoenv.2022.114163_bib44","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1016\/j.fertnstert.2011.03.059","article-title":"Mitochondrial membrane potential profile and its correlation with increasing sperm motility","volume":"95","author":"Paoli","year":"2011","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.ecoenv.2022.114163_bib45","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/S0092-8674(03)00083-7","article-title":"Un m\u00e9nage \u00e0 quatre: the molecular biology of chromosome segregation in meiosis","volume":"112","author":"Petronczki","year":"2003","journal-title":"Cell"},{"key":"10.1016\/j.ecoenv.2022.114163_bib46","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/S1097-2765(00)80069-6","article-title":"Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmc1, a germline-specific RecA homolog","volume":"1","author":"Pittman","year":"1998","journal-title":"Mol. Cell"},{"key":"10.1016\/j.ecoenv.2022.114163_bib47","doi-asserted-by":"crossref","first-page":"2416","DOI":"10.1210\/en.2015-1927","article-title":"GATA4 regulates blood-testis barrier function and lactate metabolism in mouse sertoli cells","volume":"157","author":"Schrade","year":"2016","journal-title":"Endocrinology"},{"key":"10.1016\/j.ecoenv.2022.114163_bib48","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.molcel.2013.11.003","article-title":"DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities","volume":"53","author":"Shibata","year":"2014","journal-title":"Mol. Cell"},{"key":"10.1016\/j.ecoenv.2022.114163_bib49","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s00412-018-0659-8","article-title":"Ki-67: more than a proliferation marker","volume":"127","author":"Sun","year":"2018","journal-title":"Chromosoma"},{"key":"10.1016\/j.ecoenv.2022.114163_bib50","doi-asserted-by":"crossref","first-page":"R1","DOI":"10.1530\/REP-14-0086","article-title":"Transgenic mouse models in the study of reproduction: insights into GATA protein function","volume":"148","author":"Tevosian","year":"2014","journal-title":"Reproduction"},{"key":"10.1016\/j.ecoenv.2022.114163_bib51","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S1872-0358(06)02004-5","article-title":"Chapter 4 Fluorine-Containing Agrochemicals: An Overview of Recent Developments","volume":"2","author":"Theodoridis","year":"2006","journal-title":"Adv. Fluor. ence"},{"key":"10.1016\/j.ecoenv.2022.114163_bib52","first-page":"69","article-title":"Resistance risk assessment within herbicide authorisation \u2013 a call for sensitivity data","author":"Ulber","year":"2013","journal-title":"PEST Manag. Sci."},{"key":"10.1016\/j.ecoenv.2022.114163_bib53","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0033209","article-title":"CIP2A promotes proliferation of spermatogonial progenitor cells and spermatogenesis in mice","volume":"7","author":"Ventela","year":"2012","journal-title":"PLOS One"},{"key":"10.1016\/j.ecoenv.2022.114163_bib54","doi-asserted-by":"crossref","first-page":"10524","DOI":"10.1074\/jbc.TM118.000372","article-title":"Homologous recombination and the repair of DNA double-strand breaks","volume":"293","author":"Wright","year":"2018","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ecoenv.2022.114163_bib55","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.mce.2009.03.003","article-title":"Male infertility caused by spermiogenic defects: Lessons from gene knockouts","volume":"306","author":"Yan","year":"2009","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.ecoenv.2022.114163_bib56","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1095\/biolreprod.107.063107","article-title":"Dimeric Transferrin Inhibits Phagocytosis of Residual Bodies by Testicular Rat Sertoli Cells1","volume":"78","author":"Yefimova","year":"2008","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.ecoenv.2022.114163_bib57","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/S1470-2045(09)70262-1","article-title":"Ki67 in breast cancer: prognostic and predictive potential","volume":"11","author":"Yerushalmi","year":"2010","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.ecoenv.2022.114163_bib58","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/humrep\/dey335","article-title":"Mitochondrial functionality modifies human sperm acrosin activity, acrosome reaction capability and chromatin integrity","volume":"34","author":"Zhang","year":"2019","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.ecoenv.2022.114163_bib59","doi-asserted-by":"crossref","first-page":"4942","DOI":"10.3390\/ijerph120504942","article-title":"Ninety day toxicity and toxicokinetics of fluorochloridone after oral administration in rats","volume":"12","author":"Zhang","year":"2015","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.ecoenv.2022.114163_bib60","doi-asserted-by":"crossref","first-page":"2681","DOI":"10.1007\/s00018-019-03101-9","article-title":"The roles and mechanisms of Leydig cells and myoid cells in regulating spermatogenesis","volume":"76","author":"Zhou","year":"2019","journal-title":"Cell. Mol. LIFE Sci."},{"key":"10.1016\/j.ecoenv.2022.114163_bib61","doi-asserted-by":"crossref","first-page":"553","DOI":"10.3390\/ijerph16040553","article-title":"The Oral NOAEL of Flurochloridone in Male Wistar Rats in Ninety-Day Subchronic Toxicity Test Was 3mg\/kg\/day","volume":"16","author":"Zhu","year":"2019","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.ecoenv.2022.114163_bib62","article-title":"Recombination, pairing, and synapsis of homologs during meiosis","volume":"7","author":"Zickler","year":"2015","journal-title":"CSH Perspect. Biol."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014765132201003X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014765132201003X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T06:02:36Z","timestamp":1758952956000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S014765132201003X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":62,"alternative-id":["S014765132201003X"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2022.114163","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-1151621\/v1","asserted-by":"object"}]},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Flurochloridone induced abnormal spermatogenesis by damaging testicular Sertoli cells in mice","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2022.114163","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"114163"}}