{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T18:06:02Z","timestamp":1791137162320,"version":"4.1.0"},"reference-count":72,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,23]],"date-time":"2022-10-23T00:00:00Z","timestamp":1666483200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.ecoenv.2022.114231","type":"journal-article","created":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T13:54:32Z","timestamp":1667224472000},"page":"114231","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"special_numbering":"C","title":["Ambient particulate matter exposure causes visual dysfunction and retinal neuronal degeneration"],"prefix":"10.1016","volume":"247","author":[{"given":"Liping","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maomao","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinghuai","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2022.114231_bib1","doi-asserted-by":"crossref","first-page":"3811","DOI":"10.1093\/nar\/gkz120","article-title":"Poly(ADP-ribosyl)ation by PARP1: reaction mechanism and regulatory proteins","volume":"47","author":"Alemasova","year":"2019","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.ecoenv.2022.114231_bib2","doi-asserted-by":"crossref","first-page":"4293","DOI":"10.1007\/s12035-021-02420-y","article-title":"Revisiting astrocytic roles in methylmercury intoxication","volume":"58","author":"Arrifano","year":"2021","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.ecoenv.2022.114231_bib3","doi-asserted-by":"crossref","first-page":"11125","DOI":"10.1158\/0008-5472.CAN-06-3174","article-title":"Tumor necrosis factor-alpha increases reactive oxygen species by inducing spermine oxidase in human lung epithelial cells: a potential mechanism for inflammation-induced carcinogenesis","volume":"66","author":"Babbar","year":"2006","journal-title":"Cancer Res"},{"key":"10.1016\/j.ecoenv.2022.114231_bib4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0127102","article-title":"A pilot study to assess effects of long-term inhalation of airborne particulate matter on early Alzheimer-like changes in the mouse brain","volume":"10","author":"Bhatt","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.ecoenv.2022.114231_bib5","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.ajpath.2019.11.009","article-title":"Erythropoietin Receptor Signaling Supports Retinal Function after Vascular Injury","volume":"190","author":"Bretz","year":"2020","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.ecoenv.2022.114231_bib6","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.preteyeres.2018.10.003","article-title":"Immune regulation in the aging retina","volume":"69","author":"Chen","year":"2019","journal-title":"Prog. Retin Eye Res"},{"key":"10.1016\/j.ecoenv.2022.114231_bib7","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.chemosphere.2016.04.052","article-title":"Evaluation of impact factors on PM2.5 based on long-term chemical components analyses in the megacity Beijing, China","volume":"155","author":"Chen","year":"2016","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2022.114231_bib8","doi-asserted-by":"crossref","first-page":"4915","DOI":"10.1167\/iovs.19-28346","article-title":"The relationship between ambient atmospheric fine particulate matter (PM2.5) and glaucoma in a large community cohort","volume":"60","author":"Chua","year":"2019","journal-title":"Invest Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.ecoenv.2022.114231_bib9","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1167\/iovs.61.5.32","article-title":"Ambient air pollution associations with retinal morphology in the UK Biobank","volume":"61","author":"Chua","year":"2020","journal-title":"Invest Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.ecoenv.2022.114231_bib10","article-title":"Association of ambient air pollution with age-related macular degeneration and retinal thickness in UK Biobank","author":"Chua","year":"2021","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.ecoenv.2022.114231_bib11","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.ecoenv.2019.02.064","article-title":"Fine particulate matter-induced cardiovascular injury is associated with NLRP3 inflammasome activation in Apo E(-\/-) mice","volume":"174","author":"Du","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2022.114231_bib12","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1038\/s41593-020-00783-4","article-title":"Reactive astrocyte nomenclature, definitions, and future directions","volume":"24","author":"Escartin","year":"2021","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.ecoenv.2022.114231_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00417-016-3548-y","article-title":"The neurovascular unit and the pathophysiologic basis of diabetic retinopathy","volume":"255","author":"Gardner","year":"2017","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.ecoenv.2022.114231_bib14","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/j.jaerosci.2004.11.015","article-title":"A new compact aerosol concentrator for use in conjunction with low flow-rate continuous aerosol instrumentation","volume":"36","author":"Geller","year":"2005","journal-title":"J. Aerosol Sci."},{"key":"10.1016\/j.ecoenv.2022.114231_bib15","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1146\/annurev.neuro.22.1.219","article-title":"Microglia as mediators of inflammatory and degenerative diseases","volume":"22","author":"Gonz\u00e1lez-Scarano","year":"1999","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.ecoenv.2022.114231_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.107776","article-title":"Neurotoxic reactive astrocytes drive neuronal death after retinal injury","volume":"31","author":"Guttenplan","year":"2020","journal-title":"Cell Rep."},{"key":"10.1016\/j.ecoenv.2022.114231_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.112866","article-title":"Magnetic resonance imaging investigations reveal that PM2.5 exposure triggers visual dysfunction in mice","volume":"227","author":"Guo","year":"2021","journal-title":"Ecotoxicology and Environmental Safety"},{"key":"10.1016\/j.ecoenv.2022.114231_bib18","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0079-6123(08)01125-4","article-title":"Astrocytes in glaucomatous optic neuropathy","volume":"173","author":"Hernandez","year":"2008","journal-title":"Prog. Brain Res"},{"key":"10.1016\/j.ecoenv.2022.114231_bib19","doi-asserted-by":"crossref","first-page":"5489476","DOI":"10.1155\/2018\/5489476","article-title":"Intravitreal injection of hydrogen peroxide induces acute retinal degeneration, apoptosis, and oxidative stress in mice","volume":"2018","author":"Huang","year":"2018","journal-title":"Oxid. Med Cell Longev."},{"key":"10.1016\/j.ecoenv.2022.114231_bib20","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1080\/08958378.2018.1508258","article-title":"The severity of lung injury and metabolic disorders induced by ambient PM2.5 exposure is associated with cumulative dose","volume":"30","author":"Jiang","year":"2018","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.ecoenv.2022.114231_bib21","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1186\/s40478-019-0767-6","article-title":"Glial pathology and retinal neurotoxicity in the anterior visual pathway in experimental autoimmune encephalomyelitis","volume":"7","author":"Jin","year":"2019","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.ecoenv.2022.114231_bib22","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21144976","article-title":"Long-Term Exposure to Urban Particulate Matter on the Ocular Surface and the Incidence of Deleterious Changes in the Cornea, Conjunctiva and Retina in Rats","volume":"21","author":"Kang","year":"2020","journal-title":"Int J. Mol. Sci."},{"key":"10.1016\/j.ecoenv.2022.114231_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.139053","article-title":"Saharan sand and dust storms and neonatal mortality: Evidence from Burkina Faso","volume":"729","author":"Karimi","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2022.114231_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.dnarep.2019.102673","article-title":"Inflammation-induced DNA damage, mutations and cancer","volume":"83","author":"Kay","year":"2019","journal-title":"DNA Repair (Amst. )"},{"key":"10.1016\/j.ecoenv.2022.114231_bib25","doi-asserted-by":"crossref","first-page":"275","DOI":"10.3109\/15569527.2015.1104329","article-title":"The acute respiratory exposure by intratracheal instillation of Sprague-Dawley rats with diesel particulate matter induces retinal thickening","volume":"35","author":"Kim","year":"2016","journal-title":"Cutan. Ocul. Toxicol."},{"key":"10.1016\/j.ecoenv.2022.114231_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.115039","article-title":"Different adverse effects of air pollutants on dry eye disease: Ozone, PM2.5, and PM10","volume":"265","author":"Kim","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2022.114231_bib27","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.tcm.2009.04.004","article-title":"Feedback mechanism between blood vessels and astrocytes in retinal vascular development","volume":"19","author":"Kubota","year":"2009","journal-title":"Trends Cardiovasc Med"},{"key":"10.1016\/j.ecoenv.2022.114231_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.114301","article-title":"Diesel particulate matter2.5 promotes epithelial-mesenchymal transition of human retinal pigment epithelial cells via generation of reactive oxygen species","volume":"262","author":"Lee","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2022.114231_bib29","article-title":"Exposure to Traffic-Related Particulate Matter 2.5 Triggers Th2-Dominant Ocular Immune Response in a Murine Model","volume":"17","author":"Lee","year":"2020","journal-title":"Int J. Environ. Res Public Health"},{"key":"10.1016\/j.ecoenv.2022.114231_bib30","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1097\/00006324-200106000-00015","article-title":"Age-related changes in the mouse outer retina","volume":"78","author":"Li","year":"2001","journal-title":"Optom. Vis. Sci."},{"key":"10.1016\/j.ecoenv.2022.114231_bib31","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.brainres.2007.10.073","article-title":"Oxidative-induced apoptosis to an immortalized ganglion cell line is caspase independent but involves the activation of poly(ADP-ribose)polymerase and apoptosis-inducing factor","volume":"1188","author":"Li","year":"2008","journal-title":"Brain Res"},{"key":"10.1016\/j.ecoenv.2022.114231_bib32","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s12989-021-00403-4","article-title":"Airborne particulate matter (PM2.5) triggers ocular hypertension and glaucoma through pyroptosis","volume":"18","author":"Li","year":"2021","journal-title":"Part Fibre Toxicol."},{"key":"10.1016\/j.ecoenv.2022.114231_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.112963","article-title":"Lifetime exposure of ambient PM2.5 elevates intraocular pressure in young mice","volume":"228","author":"Li","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2022.114231_bib34","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.toxlet.2018.11.012","article-title":"PM2.5 exposure exacerbates allergic rhinitis in mice by increasing DNA methylation in the IFN-gamma gene promoter in CD4+T cells via the ERK-DNMT pathway","volume":"301","author":"Li","year":"2019","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.ecoenv.2022.114231_bib35","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1080\/08958370590912743","article-title":"Effects of subchronic exposures to concentrated ambient particles (CAPs) in mice: II. The design of a CAPs exposure system for biometric telemetry monitoring","volume":"17","author":"Maciejczyk","year":"2005","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.ecoenv.2022.114231_bib36","article-title":"The role of PARP1 in neurodegenerative diseases and aging","author":"Mao","year":"2021","journal-title":"FEBS J."},{"key":"10.1016\/j.ecoenv.2022.114231_bib37","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1167\/iovs.14-15828","article-title":"DNA damage, poly(ADP-Ribose) polymerase activation, and phosphorylated histone H2AX expression during postnatal retina development in C57BL\/6 mouse","volume":"56","author":"Martin-Oliva","year":"2015","journal-title":"Invest Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.ecoenv.2022.114231_bib38","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.neuron.2012.10.002","article-title":"The neuronal organization of the retina","volume":"76","author":"Masland","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.ecoenv.2022.114231_bib39","doi-asserted-by":"crossref","first-page":"5473","DOI":"10.1167\/iovs.18-25310","article-title":"Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Promote Neuroprotection in a Genetic DBA\/2J Mouse Model of Glaucoma","volume":"59","author":"Mead","year":"2018","journal-title":"Invest Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.ecoenv.2022.114231_bib40","doi-asserted-by":"crossref","first-page":"625","DOI":"10.4103\/1673-5374.266910","article-title":"Neuroinflammation and oxidative stress act in concert to promote neurodegeneration in the diabetic retina and optic nerve: galectin-3 participation","volume":"15","author":"Mendonca","year":"2020","journal-title":"Neural Regen. Res"},{"key":"10.1016\/j.ecoenv.2022.114231_bib41","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.scitotenv.2014.04.057","article-title":"Airborne particulate matter (PM2.5) and the prevalence of allergic conjunctivitis in Japan","volume":"487","author":"Mimura","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2022.114231_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2019.108910","article-title":"Indoor PM2.5, tobacco smoking and chronic lung diseases: A narrative review","volume":"181","author":"Ni","year":"2020","journal-title":"Environ. Res"},{"key":"10.1016\/j.ecoenv.2022.114231_bib43","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1080\/08958370490439597","article-title":"Translocation of inhaled ultrafine particles to the brain","volume":"16","author":"Oberdorster","year":"2004","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.ecoenv.2022.114231_bib44","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1262\/jrd.17045","article-title":"Tumor necrosis factor-alpha induces apoptosis in cultured porcine luteal cells","volume":"52","author":"Okano","year":"2006","journal-title":"J. Reprod. Dev."},{"key":"10.1016\/j.ecoenv.2022.114231_bib45","article-title":"Pollution Weather Prediction System: Smart Outdoor Pollution Monitoring and Prediction for Healthy Breathing and Living","volume":"20","author":"Pandya","year":"2020","journal-title":"Sens. (Basel)"},{"key":"10.1016\/j.ecoenv.2022.114231_bib46","doi-asserted-by":"crossref","first-page":"10311","DOI":"10.1523\/JNEUROSCI.1514-07.2007","article-title":"Excessive activation of poly(ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse","volume":"27","author":"Paquet-Durand","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ecoenv.2022.114231_bib47","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1136\/bjo.67.7.443","article-title":"Relationship between the amplitudes of the b wave and the a wave as a useful index for evaluating the electroretinogram","volume":"67","author":"Perlman","year":"1983","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.ecoenv.2022.114231_bib48","doi-asserted-by":"crossref","DOI":"10.1289\/EHP2152","article-title":"The Association of Long-Term Exposure to Particulate Matter Air Pollution with Brain MRI Findings: The ARIC Study","volume":"126","author":"Power","year":"2018","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ecoenv.2022.114231_bib49","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1515\/reveh-2020-0017","article-title":"Effect of particulate matter 2.5 exposure to urinary malondialdehyde levels of public transport drivers in Jakarta","volume":"35","author":"Pratiwi","year":"2020","journal-title":"Rev. Environ. Health"},{"key":"10.1016\/j.ecoenv.2022.114231_bib50","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2117083119","article-title":"Passage of exogeneous fine particles from the lung into the brain in humans and animals","volume":"119","author":"Qi","year":"2022","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ecoenv.2022.114231_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.110827","article-title":"Chemical identity and cardiovascular toxicity of hydrophobic organic components in PM2.5","volume":"201","author":"Qi","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2022.114231_bib52","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.preteyeres.2004.07.002","article-title":"Visually evoked hemodynamical response and assessment of neurovascular coupling in the optic nerve and retina","volume":"24","author":"Riva","year":"2005","journal-title":"Prog. Retin Eye Res"},{"key":"10.1016\/j.ecoenv.2022.114231_bib53","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1002\/cne.23521","article-title":"The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina","volume":"522","author":"Rodriguez","year":"2014","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.ecoenv.2022.114231_bib54","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.mrfmmm.2006.11.033","article-title":"Oxidative and nitrosative stress markers in bus drivers","volume":"617","author":"Rossner","year":"2007","journal-title":"Mutat. Res"},{"key":"10.1016\/j.ecoenv.2022.114231_bib55","doi-asserted-by":"crossref","first-page":"761","DOI":"10.3233\/JAD-200919","article-title":"Particulate matter exposure exacerbates amyloid-beta plaque deposition and gliosis in APP\/PS1 mice","volume":"80","author":"Sahu","year":"2021","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.ecoenv.2022.114231_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2020.107997","article-title":"A pyruvate dehydrogenase kinase inhibitor prevents retinal cell death and improves energy metabolism in rat retinas after ischemia\/reperfusion injury","volume":"193","author":"Sato","year":"2020","journal-title":"Exp. Eye Res"},{"key":"10.1016\/j.ecoenv.2022.114231_bib57","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0011863","article-title":"Astrocyte-derived vascular endothelial growth factor stabilizes vessels in the developing retinal vasculature","volume":"5","author":"Scott","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.ecoenv.2022.114231_bib58","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/j.scitotenv.2018.09.085","article-title":"PM2.5-induced alteration of DNA methylation and RNA-transcription are associated with inflammatory response and lung injury","volume":"650","author":"Shi","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2022.114231_bib59","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1167\/iovs.61.4.23","article-title":"Airborne Particulates Affect Corneal Homeostasis and Immunity","volume":"61","author":"Somayajulu","year":"2020","journal-title":"Invest Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.ecoenv.2022.114231_bib60","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.tox.2016.07.006","article-title":"On the contribution of the phagocytosis and the solubilization to the iron oxide nanoparticles retention in and elimination from lungs under long-term inhalation exposure","volume":"363\u2013364","author":"Sutunkova","year":"2016","journal-title":"Toxicology"},{"key":"10.1016\/j.ecoenv.2022.114231_bib61","doi-asserted-by":"crossref","DOI":"10.21769\/BioProtoc.3263","article-title":"Determining oxidative damage by lipid peroxidation assay in rat serum","volume":"9","author":"Tang","year":"2019","journal-title":"Bio Protoc."},{"key":"10.1016\/j.ecoenv.2022.114231_bib62","doi-asserted-by":"crossref","first-page":"8693","DOI":"10.1523\/JNEUROSCI.20-23-08693.2000","article-title":"Increased production of tumor necrosis factor-alpha by glial cells exposed to simulated ischemia or elevated hydrostatic pressure induces apoptosis in cocultured retinal ganglion cells","volume":"20","author":"Tezel","year":"2000","journal-title":"J. Neurosci.: Off. J. Soc. Neurosci."},{"key":"10.1016\/j.ecoenv.2022.114231_bib63","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ab.2016.10.021","article-title":"Assessment of lipid peroxidation by measuring malondialdehyde (MDA) and relatives in biological samples: Analytical and biological challenges","volume":"524","author":"Tsikas","year":"2017","journal-title":"Anal. Biochem"},{"key":"10.1016\/j.ecoenv.2022.114231_bib64","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1097\/FTD.0000000000000818","article-title":"The Impact of Air Pollution on Neurodegenerative Diseases","volume":"43","author":"Wang","year":"2021","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.ecoenv.2022.114231_bib65","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s12989-018-0252-6","article-title":"Exposure to concentrated ambient PM2.5 alters the composition of gut microbiota in a murine model","volume":"15","author":"Wang","year":"2018","journal-title":"Part Fibre Toxicol."},{"key":"10.1016\/j.ecoenv.2022.114231_bib66","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.gpb.2016.05.001","article-title":"Functions of PARylation in DNA damage repair pathways","volume":"14","author":"Wei","year":"2016","journal-title":"Genom. Proteom. Bioinforma."},{"key":"10.1016\/j.ecoenv.2022.114231_bib67","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1016\/j.visres.2007.03.023","article-title":"Cone-based vision in the aging mouse","volume":"47","author":"Williams","year":"2007","journal-title":"Vis. Res"},{"key":"10.1016\/j.ecoenv.2022.114231_bib68","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.exer.2017.02.014","article-title":"Neuroinflammation in glaucoma: A new opportunity","volume":"157","author":"Williams","year":"2017","journal-title":"Exp. Eye Res"},{"key":"10.1016\/j.ecoenv.2022.114231_bib69","doi-asserted-by":"crossref","first-page":"36136","DOI":"10.1007\/s11356-018-3492-y","article-title":"Effect of PM2.5 environmental pollution on rat lung","volume":"25","author":"Yang","year":"2018","journal-title":"Environ. Sci. Pollut. Res Int"},{"key":"10.1016\/j.ecoenv.2022.114231_bib70","doi-asserted-by":"crossref","first-page":"37502","DOI":"10.1007\/s11356-020-09996-3","article-title":"The contribution of PM2.5 to cardiovascular disease in China","volume":"27","author":"Zhang","year":"2020","journal-title":"Environ. Sci. Pollut. Res Int"},{"key":"10.1016\/j.ecoenv.2022.114231_bib71","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.3389\/fnins.2018.01000","article-title":"Gestational Exposure to Particulate Matter 2.5 (PM2.5) Leads to Spatial Memory Dysfunction and Neurodevelopmental Impairment in Hippocampus of Mice Offspring","volume":"12","author":"Zheng","year":"2018","journal-title":"Front Neurosci."},{"key":"10.1016\/j.ecoenv.2022.114231_bib72","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.actbio.2019.08.032","article-title":"A superoxide scavenging coating for improving tissue response to neural implants","volume":"99","author":"Zheng","year":"2019","journal-title":"Acta Biomater."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651322010715?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651322010715?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T06:04:42Z","timestamp":1758953082000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651322010715"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":72,"alternative-id":["S0147651322010715"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2022.114231","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ambient particulate matter exposure causes visual dysfunction and retinal neuronal degeneration","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2022.114231","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"114231"}}