{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:31:25Z","timestamp":1786987885328,"version":"build-2736575974"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,18]],"date-time":"2023-06-18T00:00:00Z","timestamp":1687046400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.ecoenv.2023.115165","type":"journal-article","created":{"date-parts":[[2023,6,21]],"date-time":"2023-06-21T00:17:48Z","timestamp":1687306668000},"page":"115165","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"special_numbering":"C","title":["Levels of PFAS concentrations in the placenta and pregnancy complications"],"prefix":"10.1016","volume":"262","author":[{"given":"Luda","family":"Groisman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamar","family":"Berman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Quinn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gali","family":"Pariente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Efrat","family":"Rorman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Karakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roni","family":"Gat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Batia","family":"Sarov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3748-2632","authenticated-orcid":false,"given":"Lena","family":"Novack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.ecoenv.2023.115165_bib1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s10903-016-0522-z","article-title":"Bedouin women's gender preferences when choosing obstetricians and gynecologists","volume":"20","author":"Amir","year":"2018","journal-title":"J. Immigr. Minor Health"},{"issue":"1","key":"10.1016\/j.ecoenv.2023.115165_bib2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s13293-023-00519-6","article-title":"Sex- and age-related differences in renal and cardiac injury and senescence in stroke-prone spontaneously hypertensive rats","volume":"14","author":"Ansari","year":"2023","journal-title":"Biol. Sex. Differ."},{"key":"10.1016\/j.ecoenv.2023.115165_bib3","unstructured":"ATSDR. Toxicological profile for perfluoroalkyls (Draft for Public Comment). 2018; Available from: https:\/\/www.atsdr.cdc.gov\/toxprofiledocs\/index.html?id=1117&tid=237."},{"key":"10.1016\/j.ecoenv.2023.115165_bib4","unstructured":"ATSDR. Understanding PFAS exposure and your body. 2022; Available from: https:\/\/www.atsdr.cdc.gov\/pfas\/health-effects\/PFAS-exposure-and-your-body.html."},{"key":"10.1016\/j.ecoenv.2023.115165_bib5","doi-asserted-by":"crossref","unstructured":"Bock, A.R. and B.E. Laird, Perfluoroalkyl substances: synthesis, applications, challenges and regulations. 2022. p. 1\u201321.","DOI":"10.1039\/9781839167591-00001"},{"key":"10.1016\/j.ecoenv.2023.115165_bib6","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.envint.2012.12.014","article-title":"Determinants of plasma concentrations of perfluoroalkyl substances in pregnant Norwegian women","volume":"54","author":"Brants\u00e6ter","year":"2013","journal-title":"Environ. Int."},{"issue":"4","key":"10.1016\/j.ecoenv.2023.115165_bib7","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1002\/ieam.258","article-title":"Perfluoroalkyl and polyfluoroalkyl substances in the environment: terminology, classification, and origins","volume":"7","author":"Buck","year":"2011","journal-title":"Integr. Environ. Assess. Manag"},{"key":"10.1016\/j.ecoenv.2023.115165_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijheh.2020.113549","article-title":"Per- and polyfluoroalkyl substances in blood plasma \u2013 results of the German environmental survey for children and adolescents 2014-2017 (GerES V)","volume":"228","author":"Duffek","year":"2020","journal-title":"Int J. Hyg. Environ. Health"},{"key":"10.1016\/j.ecoenv.2023.115165_bib9","unstructured":"Exposure to PFAS (per- and polyfluoroalkyl compounds) Among adults in Israel: results from a pilot study., I.M.o. Health, Editor. 2022."},{"issue":"11","key":"10.1016\/j.ecoenv.2023.115165_bib10","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1289\/ehp.10506","article-title":"Perfluorinated chemicals and fetal growth: a study within the Danish national birth cohort","volume":"115","author":"Fei","year":"2007","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ecoenv.2023.115165_bib11","unstructured":"Gat. Negev Bio-Bank (NBB). 2022 [cited 2022 February 23]; Available from: \u3008https:\/\/negevbiobank.org.il\/\u3009."},{"issue":"12","key":"10.1016\/j.ecoenv.2023.115165_bib12","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1039\/D0EM00291G","article-title":"An overview of the uses of per- and polyfluoroalkyl substances (PFAS)","volume":"22","author":"Gl\u00fcge","year":"2020","journal-title":"Environ. Sci. Process Impacts"},{"key":"10.1016\/j.ecoenv.2023.115165_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.133873","article-title":"Concentrations of per- and polyfluoroalkyl substances (PFAS) in human placental tissues and associations with birth outcomes","volume":"295","author":"Hall","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2023.115165_bib14","unstructured":"HBM4EU, Policy brief - PFAS. 2022."},{"key":"10.1016\/j.ecoenv.2023.115165_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.120828","article-title":"Exposure to endocrine-disrupting chemicals and risk of gestational hypertension and preeclampsia: a systematic review and meta-analysis","volume":"317","author":"Hirke","year":"2023","journal-title":"Environ. Pollut."},{"issue":"1","key":"10.1016\/j.ecoenv.2023.115165_bib16","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s12940-018-0445-3","article-title":"Prenatal exposure to perfluoroalkyl and polyfluoroalkyl substances and the risk of hypertensive disorders of pregnancy","volume":"18","author":"Huang","year":"2019","journal-title":"Environ. Health"},{"key":"10.1016\/j.ecoenv.2023.115165_bib17","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.envres.2019.04.034","article-title":"Perfluoroalkyl acids serum concentrations and their relationship to biomarkers of renal failure: serum and urine albumin, creatinine, and albumin creatinine ratios across the spectrum of glomerular function among US adults","volume":"174","author":"Jain","year":"2019","journal-title":"Environ. Res."},{"issue":"Pt 1","key":"10.1016\/j.ecoenv.2023.115165_bib18","article-title":"Associations between the concentrations of \u03b1-klotho and selected perfluoroalkyl substances in the presence of eGFR based kidney function and albuminuria: data for US adults aged 40-79 years","volume":"838","author":"Jain","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2023.115165_bib19","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.scitotenv.2015.02.056","article-title":"Exposure to metals and congenital anomalies: a biomonitoring study of pregnant Bedouin-Arab women","volume":"517","author":"Karakis","year":"2015","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2023.115165_bib20","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.envres.2016.02.037","article-title":"Perfluoroalkyl substances in serum from South Korean infants with congenital hypothyroidism and healthy infants--Its relationship with thyroid hormones","volume":"147","author":"Kim","year":"2016","journal-title":"Environ. Res"},{"key":"10.1016\/j.ecoenv.2023.115165_bib21","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.chemosphere.2015.06.091","article-title":"Nitrogen Dioxide pollution and hazardous household environment: what impacts more congenital malformations","volume":"139","author":"Landau","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2023.115165_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107198","article-title":"Determinants of serum half-lives for linear and branched perfluoroalkyl substances after long-term high exposure \u2013 a study in Ronneby, Sweden","volume":"163","author":"Li","year":"2022","journal-title":"Environ. Int."},{"issue":"11","key":"10.1016\/j.ecoenv.2023.115165_bib23","doi-asserted-by":"crossref","DOI":"10.1289\/EHP10125","article-title":"Developing an exposure burden score for chemical mixtures using item response theory, with applications to PFAS mixtures","volume":"130","author":"Liu","year":"2022","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ecoenv.2023.115165_bib24","series-title":"Large Volume Direct Injection for Analysis of Perfluorinated Alkyl Substances (PFAS) in Environmental Water Samples in Accordance with ASTM 7917-17","author":"Organtini","year":"2020"},{"key":"10.1016\/j.ecoenv.2023.115165_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106678","article-title":"Trends in environmental chemical concentrations in the Canadian population: biomonitoring data from the Canadian health measures survey 2007-2017","volume":"155","author":"Pollock","year":"2021","journal-title":"Environ. Int"},{"key":"10.1016\/j.ecoenv.2023.115165_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107335","article-title":"Early-pregnancy plasma per- and polyfluoroalkyl substance (PFAS) concentrations and hypertensive disorders of pregnancy in the Project Viva cohort","volume":"165","author":"Preston","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.ecoenv.2023.115165_bib27","unstructured":"Probable Link Evaluation of Pregnancy Induced Hypertension and Preeclampsia . 2011, C8 Science Pannel."},{"issue":"9","key":"10.1016\/j.ecoenv.2023.115165_bib28","doi-asserted-by":"crossref","first-page":"96003","DOI":"10.1289\/EHP11185","article-title":"Epidemiology evidence for health effects of 150 per- and polyfluoroalkyl substances: a systematic evidence map","volume":"130","author":"Radke","year":"2022","journal-title":"Environ. Health Perspect."},{"issue":"3","key":"10.1016\/j.ecoenv.2023.115165_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajogmf.2021.100308","article-title":"Exposure to toxic metals and per- and polyfluoroalkyl substances and the risk of preeclampsia and preterm birth in the United States: a review","volume":"3","author":"Stone","year":"2021","journal-title":"Am. J. Obstet. Gynecol. MFM"},{"key":"10.1016\/j.ecoenv.2023.115165_bib30","unstructured":"Survey results of the Presence of PFAS Substances in Israel Drinking Water Wells., I.M.o. Health., Editor. 2022."},{"key":"10.1016\/j.ecoenv.2023.115165_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2020.121577","article-title":"Assessment of perfluoroalkyl substances in placenta by coupling salt assisted liquid-liquid extraction with dispersive liquid-liquid microextraction prior to liquid chromatography-tandem mass spectrometry","volume":"221","author":"Vela-Soria","year":"2021","journal-title":"Talanta"},{"key":"10.1016\/j.ecoenv.2023.115165_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijheh.2021.113904","article-title":"Association between per- and polyfluoroalkyl substances and risk of gestational diabetes mellitus","volume":"240","author":"Wang","year":"2022","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"10.1016\/j.ecoenv.2023.115165_bib33","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.jes.2018.03.016","article-title":"Association of serum levels of perfluoroalkyl substances with gestational diabetes mellitus and postpartum blood glucose","volume":"69","author":"Wang","year":"2018","journal-title":"J. Environ. Sci."},{"key":"10.1016\/j.ecoenv.2023.115165_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106621","article-title":"Environmental exposure to perfluoroalkyl substances in early pregnancy, maternal glucose homeostasis and the risk of gestational diabetes: a prospective cohort study","volume":"156","author":"Yu","year":"2021","journal-title":"Environ. Int."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651323006693?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651323006693?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T06:20:54Z","timestamp":1758954054000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651323006693"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":34,"alternative-id":["S0147651323006693"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2023.115165","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Levels of PFAS concentrations in the placenta and pregnancy complications","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2023.115165","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"115165"}}