{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T12:01:57Z","timestamp":1792497717626,"version":"4.5.0"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T00:00:00Z","timestamp":1699660800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62006113"],"award-info":[{"award-number":["62006113"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22276093"],"award-info":[{"award-number":["22276093"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.ecoenv.2023.115685","type":"journal-article","created":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T23:06:00Z","timestamp":1700089560000},"page":"115685","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"special_numbering":"C","title":["Toxicity assessment of organophosphate flame retardant triphenyl phosphate (TPHP) on intestines in mice"],"prefix":"10.1016","volume":"268","author":[{"given":"Chunyan","family":"Peng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yabing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.ecoenv.2023.115685_bib1","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1016\/j.chemosphere.2012.03.100","article-title":"Occurrence of alternative flame retardants in indoor dust from New Zealand: indoor sources and human exposure assessment","volume":"88","author":"Ali","year":"2012","journal-title":"Chemosphere"},{"issue":"20","key":"10.1016\/j.ecoenv.2023.115685_bib2","doi-asserted-by":"crossref","first-page":"4794","DOI":"10.3748\/wjg.v22.i20.4794","article-title":"Inflammatory bowel disease and cancer: the role of inflammation, immunosuppression, and cancer treatment","volume":"22","author":"Axelrad","year":"2016","journal-title":"World J. Gastroenterol."},{"issue":"4","key":"10.1016\/j.ecoenv.2023.115685_bib3","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1136\/gutjnl-2011-301397","article-title":"Epidemiology, Natural History Task Force of the International Organization for the Study of Inflammatory Bowel D. Hospitalisations and surgery in Crohn's disease","volume":"61","author":"Bernstein","year":"2012","journal-title":"Gut"},{"issue":"1","key":"10.1016\/j.ecoenv.2023.115685_bib4","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1017\/S0007114516004037","article-title":"Can probiotics modulate human disease by impacting intestinal barrier function?","volume":"117","author":"Bron","year":"2017","journal-title":"Br. J. Nutr."},{"issue":"1","key":"10.1016\/j.ecoenv.2023.115685_bib5","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a029314","article-title":"Cell biology of tight junction barrier regulation and mucosal disease","volume":"10","author":"Buckley","year":"2018","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.ecoenv.2023.115685_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.128346","article-title":"Cadmium induced BEAS-2B cells apoptosis and mitochondria damage via MAPK signaling pathway","volume":"263","author":"Cao","year":"2021","journal-title":"Chemosphere"},{"issue":"7","key":"10.1016\/j.ecoenv.2023.115685_bib7","doi-asserted-by":"crossref","first-page":"3880","DOI":"10.1021\/acs.est.8b07053","article-title":"Influence of air pollution on inhalation and dermal exposure of human to organophosphate flame retardants: a case study during a prolonged haze episode","volume":"53","author":"Cao","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ecoenv.2023.115685_bib8","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.envint.2017.12.005","article-title":"Paternal urinary concentrations of organophosphate flame retardant metabolites, fertility measures, and pregnancy outcomes among couples undergoing in vitro fertilization","volume":"111","author":"Carignan","year":"2018","journal-title":"Environ. Int."},{"key":"10.1016\/j.ecoenv.2023.115685_bib9","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.chemosphere.2017.03.076","article-title":"Flame retardants and their metabolites in the homes and urine of pregnant women residing in California (the CHAMACOS cohort)","volume":"179","author":"Castorina","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2023.115685_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.145404","article-title":"Organophosphorus flame retardants in breast milk from Beijing, China: occurrence, nursing infant's exposure and risk assessment","volume":"771","author":"Chen","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2023.115685_bib11","article-title":"Adverse health effects of emerging contaminants on inflammatory bowel disease","volume":"11","author":"Chen","year":"2023","journal-title":"Front Public Health"},{"issue":"10","key":"10.1016\/j.ecoenv.2023.115685_bib12","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.chemosphere.2012.03.067","article-title":"Phosphorus flame retardants: properties, production, environmental occurrence, toxicity and analysis","volume":"88","author":"van der Veen","year":"2012","journal-title":"Chemosphere"},{"issue":"10","key":"10.1016\/j.ecoenv.2023.115685_bib13","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1093\/ibd\/izab029","article-title":"Human intestinal macrophages are involved in the pathology of both ulcerative colitis and crohn disease","volume":"27","author":"Dharmasiri","year":"2021","journal-title":"Inflamm. Bowel Dis."},{"key":"10.1016\/j.ecoenv.2023.115685_bib14","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.scitotenv.2016.02.171","article-title":"Organophosphate ester flame retardants and plasticizers in human placenta in Eastern China","volume":"554\u2013555","author":"Ding","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2023.115685_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107503","article-title":"Exposure assessment of aryl-organophosphate esters based on specific urinary biomarkers and their associations with reproductive hormone homeostasis disruption in women of childbearing age","volume":"169","author":"Gao","year":"2022","journal-title":"Environ. Int"},{"key":"10.1016\/j.ecoenv.2023.115685_bib16","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.01094","article-title":"Dysregulation of intestinal epithelial cell RIPK pathways promotes chronic inflammation in the IBD gut","volume":"10","author":"Garcia-Carbonell","year":"2019","journal-title":"Front Immunol."},{"issue":"6","key":"10.1016\/j.ecoenv.2023.115685_bib17","doi-asserted-by":"crossref","first-page":"883","DOI":"10.7326\/0003-4819-105-6-883","article-title":"Increased intestinal permeability in patients with Crohn's disease and their relatives. A possible etiologic factor","volume":"105","author":"Hollander","year":"1986","journal-title":"Ann. Intern Med."},{"key":"10.1016\/j.ecoenv.2023.115685_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.112605","article-title":"Bone developmental toxicity of organophosphorus flame retardants TDCIPP and TPhP in marine medaka Oryzias melastigma","volume":"223","author":"Hong","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"6","key":"10.1016\/j.ecoenv.2023.115685_bib19","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1177\/0734904107083553","article-title":"The potential for volatile phosphorus-containing flame retardants in textile back-coatings","volume":"25","author":"Horrocks","year":"2016","journal-title":"J. Fire Sci."},{"key":"10.1016\/j.ecoenv.2023.115685_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105698","article-title":"Organophosphate esters and their metabolites in paired human whole blood, serum, and urine as biomarkers of exposure","volume":"139","author":"Hou","year":"2020","journal-title":"Environ. Int"},{"issue":"12","key":"10.1016\/j.ecoenv.2023.115685_bib21","doi-asserted-by":"crossref","first-page":"8221","DOI":"10.1021\/acs.est.2c01850","article-title":"Penetration of organophosphate triesters and diesters across the blood-cerebrospinal fluid barrier: efficiencies, impact factors, and mechanisms","volume":"56","author":"Hou","year":"2022","journal-title":"Environ. Sci. Technol."},{"issue":"9","key":"10.1016\/j.ecoenv.2023.115685_bib22","doi-asserted-by":"crossref","first-page":"3549","DOI":"10.1021\/acs.est.2c05619","article-title":"Bioaccumulation and trophic transfer of organophosphate flame retardants and their metabolites in the estuarine food web of the Pearl River, China","volume":"57","author":"Huang","year":"2023","journal-title":"Environ. Sci. Technol."},{"issue":"12","key":"10.1016\/j.ecoenv.2023.115685_bib23","doi-asserted-by":"crossref","first-page":"3653","DOI":"10.1016\/j.envpol.2011.07.020","article-title":"Levels and distribution of organophosphorus flame retardants and plasticizers in fishes from Manila Bay, the Philippines","volume":"159","author":"Kim","year":"2011","journal-title":"Environ. Pollut."},{"issue":"1","key":"10.1016\/j.ecoenv.2023.115685_bib24","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.tox.2013.09.004","article-title":"In vitro endocrine disruption potential of organophosphate flame retardants via human nuclear receptors","volume":"314","author":"Kojima","year":"2013","journal-title":"Toxicology"},{"key":"10.1016\/j.ecoenv.2023.115685_bib25","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.watres.2014.01.031","article-title":"Occurrence of organophosphate flame retardants in drinking water from China","volume":"54","author":"Li","year":"2014","journal-title":"Water Res."},{"key":"10.1016\/j.ecoenv.2023.115685_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.113707","article-title":"Occupational exposure to organophosphate esters in e-waste dismantling workers: Risk assessment and influencing factors screening","volume":"240","author":"Li","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"18","key":"10.1016\/j.ecoenv.2023.115685_bib27","doi-asserted-by":"crossref","first-page":"7109","DOI":"10.1021\/acs.est.2c06503","article-title":"Organophosphate flame retardants in pregnant women: sources, occurrence, and potential risks to pregnancy outcomes","volume":"57","author":"Li","year":"2023","journal-title":"Environ. Sci. Technol."},{"issue":"1\u20133","key":"10.1016\/j.ecoenv.2023.115685_bib28","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.ejphar.2012.07.031","article-title":"NG, a novel PABA\/NO-based oleanolic acid derivative, induces human hepatoma cell apoptosis via a ROS\/MAPK-dependent mitochondrial pathway","volume":"691","author":"Liu","year":"2012","journal-title":"Eur. J. Pharm."},{"issue":"12","key":"10.1016\/j.ecoenv.2023.115685_bib29","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1111\/1751-2980.12095","article-title":"Activation of PI3K\/Akt\/mTOR signaling pathway triggered by PTEN downregulation in the pathogenesis of Crohn's disease","volume":"14","author":"Long","year":"2013","journal-title":"J. Dig. Dis."},{"key":"10.1016\/j.ecoenv.2023.115685_bib30","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.aquatox.2019.04.018","article-title":"Microcystin-LR-regulated transcriptome dynamics in ZFL cells","volume":"212","author":"Lu","year":"2019","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.ecoenv.2023.115685_bib31","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.envint.2014.09.006","article-title":"Human health risk associated with brominated flame-retardants (BFRs)","volume":"74","author":"Lyche","year":"2015","journal-title":"Environ. Int."},{"key":"10.1016\/j.ecoenv.2023.115685_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.118096","article-title":"Triphenyl phosphate delayed pubertal timing and induced decline of ovarian reserve in mice as an estrogen receptor antagonist","volume":"290","author":"Ma","year":"2021","journal-title":"Environ. Pollut."},{"issue":"3","key":"10.1016\/j.ecoenv.2023.115685_bib33","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1289\/ehp.0901332","article-title":"House dust concentrations of organophosphate flame retardants in relation to hormone levels and semen quality parameters","volume":"118","author":"Meeker","year":"2010","journal-title":"Environ. Health Perspect."},{"issue":"1","key":"10.1016\/j.ecoenv.2023.115685_bib34","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/toxsci\/kfy037","article-title":"Disruption of nuclear receptor signaling alters triphenyl phosphate-induced cardiotoxicity in zebrafish embryos","volume":"163","author":"Mitchell","year":"2018","journal-title":"Toxicol. Sci."},{"issue":"2","key":"10.1016\/j.ecoenv.2023.115685_bib35","doi-asserted-by":"crossref","first-page":"27","DOI":"10.4103\/0976-0105.177703","article-title":"A simple practice guide for dose conversion between animals and human","volume":"7","author":"Nair","year":"2016","journal-title":"J. Basic Clin. Pharm."},{"key":"10.1016\/j.ecoenv.2023.115685_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.117855","article-title":"An adverse outcome pathway based in vitro characterization of novel flame retardants-induced hepatic steatosis","volume":"289","author":"Negi","year":"2021","journal-title":"Environ. Pollut."},{"issue":"7534","key":"10.1016\/j.ecoenv.2023.115685_bib37","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1038\/nature14191","article-title":"Necroptosis and its role in inflammation","volume":"517","author":"Pasparakis","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.ecoenv.2023.115685_bib38","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.scitotenv.2018.02.053","article-title":"Organophosphate flame retardants and plasticizers in indoor dust, air and window wipes in newly built low-energy preschools","volume":"628\u2013629","author":"Persson","year":"2018","journal-title":"Sci. Total Environ."},{"issue":"3","key":"10.1016\/j.ecoenv.2023.115685_bib39","doi-asserted-by":"crossref","DOI":"10.1053\/j.gastro.2019.04.016","article-title":"Environmental risk factors for inflammatory bowel diseases: an umbrella review of meta-analyses","volume":"157","author":"Piovani","year":"2019","journal-title":"Gastroenterology"},{"key":"10.1016\/j.ecoenv.2023.115685_bib40","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.envint.2017.01.020","article-title":"Associations between urinary diphenyl phosphate and thyroid function","volume":"101","author":"Preston","year":"2017","journal-title":"Environ. Int"},{"key":"10.1016\/j.ecoenv.2023.115685_bib41","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.freeradbiomed.2019.04.025","article-title":"Hydrogen sulfide protects against DSS-induced colitis by inhibiting NLRP3 inflammasome","volume":"137","author":"Qin","year":"2019","journal-title":"Free Radic. Biol. Med."},{"issue":"9","key":"10.1016\/j.ecoenv.2023.115685_bib42","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.trac.2008.07.002","article-title":"Organophosphorus flame retardants and plasticizers in water and air I. Occurrence and fate","volume":"27","author":"Reemtsma","year":"2008","journal-title":"TrAC Trends Anal. Chem."},{"issue":"14","key":"10.1016\/j.ecoenv.2023.115685_bib43","doi-asserted-by":"crossref","first-page":"4097","DOI":"10.1016\/j.watres.2010.05.024","article-title":"Occurrence and fate of organophosphorus flame retardants and plasticizers in urban and remote surface waters in Germany","volume":"44","author":"Regnery","year":"2010","journal-title":"Water Res."},{"issue":"1","key":"10.1016\/j.ecoenv.2023.115685_bib44","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1093\/advances\/nmz061","article-title":"Negative effects of a high-fat diet on intestinal permeability: a review","volume":"11","author":"Rohr","year":"2020","journal-title":"Adv. Nutr."},{"issue":"14","key":"10.1016\/j.ecoenv.2023.115685_bib45","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22147618","article-title":"Innate lymphoid cells in intestinal homeostasis and inflammatory bowel disease","volume":"22","author":"Saez","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"3","key":"10.1016\/j.ecoenv.2023.115685_bib46","doi-asserted-by":"crossref","DOI":"10.1053\/j.gastro.2021.10.035","article-title":"Colorectal cancer in inflammatory bowel disease: mechanisms and management","volume":"162","author":"Shah","year":"2022","journal-title":"Gastroenterology"},{"key":"10.1016\/j.ecoenv.2023.115685_bib47","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.aquatox.2018.08.001","article-title":"Developmental neurotoxicity of triphenyl phosphate in zebrafish larvae","volume":"203","author":"Shi","year":"2018","journal-title":"Aquat. Toxicol."},{"issue":"48","key":"10.1016\/j.ecoenv.2023.115685_bib48","doi-asserted-by":"crossref","first-page":"68276","DOI":"10.1007\/s11356-021-15405-0","article-title":"Ambient PM(2.5)-induced brain injury is associated with the activation of PI3K\/AKT\/FoxO1 pathway.","volume":"28","author":"Song","year":"2021","journal-title":"Environ. Sci. Pollut. Res. Int."},{"issue":"4","key":"10.1016\/j.ecoenv.2023.115685_bib49","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1039\/b921910b","article-title":"Organophosphorus flame retardants and plasticizers in marine and fresh water biota and in human milk","volume":"12","author":"Sundkvist","year":"2010","journal-title":"J. Environ. Monit."},{"issue":"4","key":"10.1016\/j.ecoenv.2023.115685_bib50","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/s00018-012-1070-x","article-title":"Regulation of intestinal epithelial permeability by tight junctions","volume":"70","author":"Suzuki","year":"2013","journal-title":"Cell Mol. Life Sci."},{"issue":"1","key":"10.1016\/j.ecoenv.2023.115685_bib51","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3892\/ijmm.2014.1981","article-title":"PI3K\/AKT\/PTEN pathway as a target for Crohn's disease therapy (Review)","volume":"35","author":"Tokuhira","year":"2015","journal-title":"Int. J. Mol. Med."},{"issue":"11","key":"10.1016\/j.ecoenv.2023.115685_bib52","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1038\/nri2653","article-title":"Intestinal mucosal barrier function in health and disease","volume":"9","author":"Turner","year":"2009","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.ecoenv.2023.115685_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.114876","article-title":"Triphenyl phosphate induced apoptosis of mice testicular Leydig cells and TM3 cells through ROS-mediated mitochondrial fusion inhibition","volume":"256","author":"Wang","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2023.115685_bib54","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.envpol.2014.12.037","article-title":"Occurrence and spatial distribution of organophosphate ester flame retardants and plasticizers in 40 rivers draining into the Bohai Sea, north China","volume":"198","author":"Wang","year":"2015","journal-title":"Environ. Pollut."},{"issue":"7803","key":"10.1016\/j.ecoenv.2023.115685_bib55","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1038\/s41586-020-2127-x","article-title":"Gut stem cell necroptosis by genome instability triggers bowel inflammation","volume":"580","author":"Wang","year":"2020","journal-title":"Nature"},{"issue":"Pt A","key":"10.1016\/j.ecoenv.2023.115685_bib56","article-title":"Occurrence and air-soil exchange of organophosphate flame retardants in the air and soil of Dalian, China","volume":"265","author":"Wang","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2023.115685_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.134502","article-title":"Organophosphate di- and tri-esters in indoor and outdoor dust from China and its implications for human exposure","volume":"700","author":"Wang","year":"2020","journal-title":"Sci. Total Environ."},{"issue":"4","key":"10.1016\/j.ecoenv.2023.115685_bib58","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.tibs.2014.02.003","article-title":"FOXO transcription factors: key regulators of cellular quality control","volume":"39","author":"Webb","year":"2014","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.ecoenv.2023.115685_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2023.107968","article-title":"Differently surface-labeled polystyrene nanoplastics at an environmentally relevant concentration induced Crohn's ileitis-like features via triggering intestinal epithelial cell necroptosis","volume":"176","author":"Xu","year":"2023","journal-title":"Environ. Int."},{"key":"10.1016\/j.ecoenv.2023.115685_bib60","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/8813558","article-title":"The function and role of the Th17\/Treg cell balance in inflammatory bowel disease","volume":"2020","author":"Yan","year":"2020","journal-title":"J. Immunol. Res."},{"issue":"4","key":"10.1016\/j.ecoenv.2023.115685_bib61","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1007\/s00244-019-00602-3","article-title":"Occurrence, distribution, and exposure risk of Organophosphate esters in street dust from Chengdu, China","volume":"76","author":"Yin","year":"2019","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.ecoenv.2023.115685_bib62","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.chemosphere.2019.01.074","article-title":"OPFRs and BFRs induced A549\u00a0cell apoptosis by caspase-dependent mitochondrial pathway","volume":"221","author":"Yu","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2023.115685_bib63","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.128368","article-title":"Adverse outcome pathway of fine particulate matter leading to increased cardiovascular morbidity and mortality: An integrated perspective from toxicology and epidemiology","volume":"430","author":"Yu","year":"2022","journal-title":"J. Hazard Mater."},{"issue":"2","key":"10.1016\/j.ecoenv.2023.115685_bib64","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1002\/etc.3996","article-title":"Occurrence and distribution of organophosphate ester flame retardants in indoor dust and their potential health exposure risk","volume":"37","author":"Zeng","year":"2018","journal-title":"Environ. Toxicol. Chem."},{"issue":"7829","key":"10.1016\/j.ecoenv.2023.115685_bib65","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1038\/s41586-020-2799-2","article-title":"A STAT3 palmitoylation cycle promotes T(H)17 differentiation and colitis","volume":"586","author":"Zhang","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.ecoenv.2023.115685_bib66","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.scitotenv.2017.07.202","article-title":"Flame retardants on the surface of phones and personal computers","volume":"609","author":"Zheng","year":"2017","journal-title":"Sci. Total Environ."},{"issue":"24","key":"10.1016\/j.ecoenv.2023.115685_bib67","doi-asserted-by":"crossref","first-page":"17858","DOI":"10.1021\/acs.est.2c05357","article-title":"Chlorinated organophosphate flame retardants impair the lung function via the IL-6\/JAK\/STAT signaling pathway","volume":"56","author":"Zhu","year":"2022","journal-title":"Environ. Sci. Technol."},{"issue":"1","key":"10.1016\/j.ecoenv.2023.115685_bib68","doi-asserted-by":"crossref","first-page":"581","DOI":"10.3892\/etm.2020.8718","article-title":"Baicalin alleviates TNBS-induced colitis by inhibiting PI3K\/AKT pathway activation","volume":"20","author":"Zhu","year":"2020","journal-title":"Exp. Ther. Med."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651323011892?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651323011892?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:03:48Z","timestamp":1777489428000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651323011892"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":68,"alternative-id":["S0147651323011892"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2023.115685","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Toxicity assessment of organophosphate flame retardant triphenyl phosphate (TPHP) on intestines in mice","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2023.115685","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"115685"}}