{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T16:54:17Z","timestamp":1784912057896,"version":"3.55.0"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.ecoenv.2024.116399","type":"journal-article","created":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T17:36:20Z","timestamp":1714152980000},"page":"116399","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["F-53B mediated ROS affects uterine development in rats during puberty by inducing apoptosis"],"prefix":"10.1016","volume":"277","author":[{"given":"Penghui","family":"Nie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuzhi","family":"Lan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"You","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiantian","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hengyi","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Supplement_1","key":"10.1016\/j.ecoenv.2024.116399_bib1","article-title":"P\u2013365 Altered endometrial oestrogen-responsiveness and aberrant expression of cell-fate markers may contribute to the aetiology of recurrent pregnancy loss","volume":"36","author":"Al-Lamee","year":"2021","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.ecoenv.2024.116399_bib2","doi-asserted-by":"crossref","DOI":"10.1096\/fasebj.2020.34.s1.00029","article-title":"Mitochondrial dysfunction contributes to germ cell apoptosis via the JNK\/p53\/survivin pathway","volume":"34","author":"Al-Maghrebi","year":"2020","journal-title":"Faseb J."},{"key":"10.1016\/j.ecoenv.2024.116399_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2019.124357","article-title":"Changes in energy metabolism induced by fluoride: Insights from inside the mitochondria","volume":"236","author":"Araujo","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2024.116399_bib4","article-title":"Clear cell carcinoma palisading in a focus of endometriosis on the uterine serosa \u2013 A case report and review of the literature","volume":"35","author":"Bahall","year":"2022","journal-title":"Case Rep. Women'S. Health"},{"issue":"3","key":"10.1016\/j.ecoenv.2024.116399_bib5","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1038\/nrendo.2016.186","article-title":"Early-life exposure to EDCs: role in childhood obesity and neurodevelopment","volume":"13","author":"Braun","year":"2017","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.ecoenv.2024.116399_bib6","series-title":"Developmental Toxicity of Perfluorooctanesulfonate (PFOS) and Its Chlorinated Polyfluoroalkyl Ether Sulfonate Alternative F-53B in the Domestic Chicken","author":"Briels","year":"2018"},{"key":"10.1016\/j.ecoenv.2024.116399_bib7","doi-asserted-by":"crossref","first-page":"S126","DOI":"10.1016\/S0378-4274(21)00543-9","article-title":"Studying the systemic effects of PFOS on the Hypothalamic-Thyroid-Pituitary (HPT) axis by transcriptomics","volume":"350","author":"Davidsen","year":"2021","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.ecoenv.2024.116399_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.153933","article-title":"Perfluorooctane sulfonate induces mitochondrial calcium overload and early hepatic insulin resistance via autophagy\/detyrosinated alpha-tubulin-regulated IP3R2-VDAC1-MICU1 interaction","volume":"825","author":"Dong","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"1","key":"10.1016\/j.ecoenv.2024.116399_bib9","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.ydbio.2016.11.023","article-title":"Porcupine-dependent Wnt signaling controls stromal proliferation and endometrial gland maintenance through the action of distinct WNTs","volume":"422","author":"Farah","year":"2017","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ecoenv.2024.116399_bib10","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.955576","article-title":"IL-22 regulates endometrial regeneration by enhancing tight junctions and orchestrating extracellular matrix","volume":"13","author":"Ganieva","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ecoenv.2024.116399_bib11","doi-asserted-by":"crossref","unstructured":"Gladysz, J.A. and M. Jurisch, Structural, Physical, and Chemical Properties of Fluorous Compounds, in Fluorous Chemistry, I.T. Horvath, Editor. 2012. p. 1-23.","DOI":"10.1007\/128_2011_282"},{"issue":"3","key":"10.1016\/j.ecoenv.2024.116399_bib12","doi-asserted-by":"crossref","first-page":"3009","DOI":"10.3390\/ijms24033009","article-title":"The co-expression of estrogen receptors ER\u03b1, ER\u03b2, and GPER in Endometrial Cancer","volume":"24","author":"Hojnik","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"5498","key":"10.1016\/j.ecoenv.2024.116399_bib13","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/254337a0","article-title":"Progesterone antagonism of the oestrogen receptor and oestrogen-induced uterine growth","volume":"254","author":"Hsueh","year":"1975","journal-title":"Nature"},{"key":"10.1016\/j.ecoenv.2024.116399_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.116051","article-title":"Bisphenol AF induces apoptosis via estrogen receptor beta (ER\u03b2) and ROS-ASK1-JNK MAPK pathway in human granulosa cell line KGN","volume":"270","author":"Huang","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2024.116399_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.121479","article-title":"Effects of PFOS, F-53B and OBS on locomotor behaviour, the dopaminergic system and mitochondrial function in developing zebrafish (Danio rerio)","volume":"326","author":"Kalyn","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2024.116399_bib16","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.chemosphere.2016.04.070","article-title":"Transcriptional changes in steroidogenesis by perfluoroalkyl acids (PFOA and PFOS) regulate the synthesis of sex hormones in H295R cells","volume":"155","author":"Kang","year":"2016","journal-title":"Chemosphere"},{"issue":"5","key":"10.1016\/j.ecoenv.2024.116399_bib17","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1210\/er.2018-00281","article-title":"Uterine glands: developmental biology and functional roles in pregnancy","volume":"40","author":"Kelleher","year":"2019","journal-title":"Endocr. Rev."},{"issue":"2","key":"10.1016\/j.ecoenv.2024.116399_bib18","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.taap.2008.11.021","article-title":"Mechanism of cytotoxic action of perfluorinated acids II. Disruption of mitochondrial bioenergetics","volume":"235","author":"Kleszczynski","year":"2009","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"8","key":"10.1016\/j.ecoenv.2024.116399_bib19","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1021\/acs.estlett.0c00255","article-title":"Scientific basis for managing PFAS as a chemical class","volume":"7","author":"Kwiatkowski","year":"2020","journal-title":"Environ. Sci. Technol. Lett."},{"key":"10.1016\/j.ecoenv.2024.116399_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.115540","article-title":"Association between exposure to persistent organic pollutants and pubertal timing in boys and girls: a systematic review and meta-analysis","volume":"265","author":"Lan","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"10119","key":"10.1016\/j.ecoenv.2024.116399_bib21","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/S0140-6736(17)32345-0","article-title":"The Lancet Commission on pollution and health","volume":"391","author":"Landrigan","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.ecoenv.2024.116399_bib22","doi-asserted-by":"crossref","DOI":"10.1177\/00220345211070583","article-title":"MSX1 drives tooth morphogenesis through controlling Wnt signaling activity","author":"Lee","year":"2022","journal-title":"J. Dent. Res."},{"issue":"5","key":"10.1016\/j.ecoenv.2024.116399_bib23","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1210\/er.2003-0035","article-title":"Estrogen regulation of growth hormone action","volume":"25","author":"Leung","year":"2004","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.ecoenv.2024.116399_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.164353","article-title":"Associations of prenatal and postnatal exposure to perfluoroalkyl substances with pubertal development and reproductive hormones in females and males: the HOME study","volume":"890","author":"Liu","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2024.116399_bib25","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.reprotox.2017.02.009","article-title":"Perinatal administration of bisphenol A alters the expression of tight junction proteins in the uterus and reduces the implantation rate","volume":"69","author":"Mart\u00ednez-Pe\u00f1a","year":"2017","journal-title":"Reprod. Toxicol."},{"issue":"4","key":"10.1016\/j.ecoenv.2024.116399_bib26","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.fertnstert.2019.02.008","article-title":"Uterine polyps, adenomyosis, leiomyomas, and endometrial receptivity","volume":"111","author":"Munro","year":"2019","journal-title":"Fertil. Steril."},{"issue":"2","key":"10.1016\/j.ecoenv.2024.116399_bib27","doi-asserted-by":"crossref","first-page":"385","DOI":"10.3892\/or_00000871","article-title":"Prognostic significance and clinical importance of estrogen receptor alpha and beta in human endometrioid adenocarcinomas","volume":"24","author":"Mylonas","year":"2010","journal-title":"Oncol. Rep."},{"key":"10.1016\/j.ecoenv.2024.116399_bib28","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2020.00545","article-title":"GPER as a receptor for endocrine-disrupting chemicals (EDCs)","volume":"11","author":"Perian","year":"2020","journal-title":"Front. Endocrinol."},{"issue":"10","key":"10.1016\/j.ecoenv.2024.116399_bib29","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.devcel.2023.03.013","article-title":"Beclin-1-dependent autophagy, but not apoptosis, is critical for stem-cell-mediated endometrial programming and the establishment of pregnancy","volume":"58","author":"Popli","year":"2023","journal-title":"Dev. Cell"},{"issue":"7","key":"10.1016\/j.ecoenv.2024.116399_bib30","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/s41574-023-00822-7","article-title":"The G protein-coupled oestrogen receptor GPER in health and disease: an update","volume":"19","author":"Prossnitz","year":"2023","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.ecoenv.2024.116399_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.162618","article-title":"Per- and polyfluoroalkyl substances (PFASs) registered under REACH\u2014What can we learn from the submitted data and how important will mobility be in PFASs hazard assessment?","volume":"877","author":"Rudin","year":"2023","journal-title":"Sci. Total Environ."},{"issue":"3_Supplement","key":"10.1016\/j.ecoenv.2024.116399_bib32","doi-asserted-by":"crossref","DOI":"10.1158\/1557-3265.ENDOMET20-PO020","article-title":"Abstract PO020: Approval for the proliferative marker Ki-67 as an integrated biomarker for endometrial cancer in NRG study GY011","volume":"27","author":"Samuelson","year":"2021","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.ecoenv.2024.116399_bib33","doi-asserted-by":"crossref","DOI":"10.3390\/cancers15102845","article-title":"Role of Estrogen Receptor \u03b2, G-Protein coupled estrogen receptor and estrogen-related receptors in endometrial and ovarian cancer","volume":"15","author":"Sch\u00fcler-Toprak","year":"2023","journal-title":"Cancers"},{"key":"10.1016\/j.ecoenv.2024.116399_bib34","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24076302","article-title":"Gender-specific impact of sex hormones on the immune system","volume":"24","author":"Sciarra","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"3","key":"10.1016\/j.ecoenv.2024.116399_bib35","doi-asserted-by":"crossref","first-page":"R101","DOI":"10.1530\/JOE-16-0157","article-title":"Myometrial cytokines and their role in the onset of labour","volume":"231","author":"Sivarajasingam","year":"2016","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.ecoenv.2024.116399_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.127565","article-title":"Effect of fluoride on endocrine tissues and their secretory functions -- review","volume":"260","author":"Sk\u00f3rka-Majewicz","year":"2020","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2024.116399_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107541","article-title":"Associations of per- and polyfluoroalkyl substances (PFAS) and their mixture with oxidative stress biomarkers during pregnancy","volume":"169","author":"Taibl","year":"2022","journal-title":"Environ. Int."},{"issue":"9","key":"10.1016\/j.ecoenv.2024.116399_bib38","doi-asserted-by":"crossref","first-page":"3794","DOI":"10.1021\/acs.est.2c09315","article-title":"Verification of in vivo estrogenic activity for four per- and polyfluoroalkyl substances (PFAS) Identified as estrogen receptor agonists via new approach methodologies","volume":"57","author":"Villeneuve","year":"2023","journal-title":"Environ. Sci. Technol."},{"issue":"7","key":"10.1016\/j.ecoenv.2024.116399_bib39","doi-asserted-by":"crossref","first-page":"947","DOI":"10.4161\/auto.6787","article-title":"Beclin 1 bridges autophagy, apoptosis and differentiation","volume":"4","author":"Wang","year":"2008","journal-title":"Autophagy"},{"issue":"18","key":"10.1016\/j.ecoenv.2024.116399_bib40","doi-asserted-by":"crossref","first-page":"10163","DOI":"10.1021\/es401525n","article-title":"First Report of a Chinese PFOS alternative overlooked for 30 years: its toxicity, persistence, and presence in the environment","volume":"47","author":"Wang","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ecoenv.2024.116399_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.110820","article-title":"Role of GH\/IGF axis in arsenite-induced developmental toxicity in zebrafish embryos","volume":"201","author":"Wang","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"1","key":"10.1016\/j.ecoenv.2024.116399_bib42","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1186\/s12906-020-02980-x","article-title":"RETRACTED ARTICLE: Ginkgolide B inhibits lung cancer cells promotion via beclin-1-dependent autophagy","volume":"20","author":"Wang","year":"2020","journal-title":"BMC Complement. Med. Ther."},{"key":"10.1016\/j.ecoenv.2024.116399_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107351","article-title":"Aberrant hepatic lipid metabolism associated with gut microbiota dysbiosis triggers hepatotoxicity of novel PFOS alternatives in adult zebrafish","author":"Wang","year":"2022","journal-title":"Environ. Int."},{"issue":"3","key":"10.1016\/j.ecoenv.2024.116399_bib44","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/s41419-019-1407-6","article-title":"BCL-2 family isoforms in apoptosis and cancer","volume":"10","author":"Warren","year":"2019","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.ecoenv.2024.116399_bib45","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.envres.2017.07.051","article-title":"Phthalate and bisphenol A exposure during in utero windows of susceptibility in relation to reproductive hormones and pubertal development in girls","volume":"159","author":"Watkins","year":"2017","journal-title":"Environ. Res."},{"key":"10.1016\/j.ecoenv.2024.116399_bib46","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.chemosphere.2014.10.014","article-title":"Perfluoroalkylated substances (PFAS) affect oxidative stress biomarkers in vitro","volume":"129","author":"Wiels\u00f8e","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2024.116399_bib47","doi-asserted-by":"crossref","DOI":"10.3390\/genes10010036","article-title":"High KRT8 expression independently predicts poor prognosis for lung adenocarcinoma patients","volume":"10","author":"Xie","year":"2019","journal-title":"Genes"},{"key":"10.1016\/j.ecoenv.2024.116399_bib48","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.chemosphere.2018.04.011","article-title":"Evaluation of the early developmental neural toxicity of F-53B, as compared to PFOS, with an in vitro mouse stem cell differentiation model","volume":"204","author":"Yin","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2024.116399_bib49","article-title":"Maternal F-53B exposure during pregnancy and lactation induced glucolipid metabolism disorders and adverse pregnancy outcomes by disturbing gut microbiota in mice","author":"Yueying","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2024.116399_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2023.153511","article-title":"The novel polyfluoroalkyl benzenesulfonate OBS exposure induces cell cycle arrest and senescence of rat pituitary cell GH3 via the p53\/p21\/RB pathway","volume":"490","author":"Zhang","year":"2023","journal-title":"Toxicology"},{"key":"10.1016\/j.ecoenv.2024.116399_bib51","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.chemosphere.2018.10.043","article-title":"Mitochondrial respiratory chain complex abnormal expressions and fusion disorder are involved in fluoride-induced mitochondrial dysfunction in ovarian granulosa cells","volume":"215","author":"Zhao","year":"2019","journal-title":"Chemosphere"}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651324004755?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651324004755?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T14:06:15Z","timestamp":1716213975000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651324004755"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":51,"alternative-id":["S0147651324004755"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2024.116399","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"F-53B mediated ROS affects uterine development in rats during puberty by inducing apoptosis","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2024.116399","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"116399"}}