{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:52:46Z","timestamp":1787237566103,"version":"build-2736575974"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,29]],"date-time":"2024-09-29T00:00:00Z","timestamp":1727568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.ecoenv.2024.117143","type":"journal-article","created":{"date-parts":[[2024,10,5]],"date-time":"2024-10-05T09:11:10Z","timestamp":1728119470000},"page":"117143","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Exposure to air pollution, genetic susceptibility, and prevalence of sarcopenia in the UK"],"prefix":"10.1016","volume":"285","author":[{"given":"Xiangliang","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuguang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangqi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naifei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiuwei","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2024.117143_bib1","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.120.016890","article-title":"Long-Term PM(2.5) exposure and risks of ischemic heart disease and stroke events: review and meta-analysis","volume":"10","author":"Alexeeff","year":"2021","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.ecoenv.2024.117143_bib2","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2024.3062","article-title":"Long-term body mass index variability and adverse cardiovascular outcomes","volume":"7","author":"Almuwaqqat","year":"2024","journal-title":"JAMA Netw. Open"},{"key":"10.1016\/j.ecoenv.2024.117143_bib3","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.maturitas.2016.11.006","article-title":"Inflammation and sarcopenia: a systematic review and meta-analysis","volume":"96","author":"Bano","year":"2017","journal-title":"Maturitas"},{"key":"10.1016\/j.ecoenv.2024.117143_bib4","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2016-011843","article-title":"Association between physical activity and body fat percentage, with adjustment for BMI: a large cross-sectional analysis of UK Biobank","volume":"7","author":"Bradbury","year":"2017","journal-title":"BMJ Open"},{"key":"10.1016\/j.ecoenv.2024.117143_bib5","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.exger.2012.10.004","article-title":"The stress of aging","volume":"48","author":"Cesari","year":"2013","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.ecoenv.2024.117143_bib6","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/ageing\/afy169","article-title":"Sarcopenia: revised European consensus on definition and diagnosis","volume":"48","author":"Cruz-Jentoft","year":"2019","journal-title":"Age Ageing"},{"key":"10.1016\/j.ecoenv.2024.117143_bib7","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1016\/S0140-6736(19)31138-9","article-title":"Sarcopenia","volume":"393","author":"Cruz-Jentoft","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.ecoenv.2024.117143_bib8","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1002\/jcsm.12503","article-title":"Sarcopenia, long-term conditions, and multimorbidity: findings from UK Biobank participants","volume":"11","author":"Dodds","year":"2020","journal-title":"J. Cachex-.-. Sarcopenia Muscle"},{"key":"10.1016\/j.ecoenv.2024.117143_bib9","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1016\/j.ajcnut.2024.03.018","article-title":"Waist-to-height ratio and body fat percentage as risk factors for ischemic cardiovascular disease: a prospective cohort study from UK Biobank","volume":"119","author":"Feng","year":"2024","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.ecoenv.2024.117143_bib10","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1093\/aje\/kwx246","article-title":"Comparison of sociodemographic and health-related characteristics of uk biobank participants with those of the general population","volume":"186","author":"Fry","year":"2017","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.ecoenv.2024.117143_bib11","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s00223-013-9830-7","article-title":"Total and appendicular lean mass reference ranges for Australian men and women: the Geelong osteoporosis study","volume":"94","author":"Gould","year":"2014","journal-title":"Calcif. Tissue Int"},{"key":"10.1016\/j.ecoenv.2024.117143_bib12","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21124306","article-title":"Ambient air pollution increases the risk of cerebrovascular and neuropsychiatric disorders through induction of inflammation and oxidative stress","volume":"21","author":"Hahad","year":"2020","journal-title":"Int J. Mol. Sci."},{"key":"10.1016\/j.ecoenv.2024.117143_bib13","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1093\/ije\/dyr154","article-title":"Environmental chemical exposures and human epigenetics","volume":"41","author":"Hou","year":"2012","journal-title":"Int J. Epidemiol."},{"key":"10.1016\/j.ecoenv.2024.117143_bib14","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.cell.2019.03.028","article-title":"Polygenic prediction of weight and obesity trajectories from birth to adulthood","volume":"177","author":"Khera","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.ecoenv.2024.117143_bib15","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1002\/jcsm.13256","article-title":"Low muscle mass, malnutrition, sarcopenia, and associations with survival in adults with cancer in the UK Biobank cohort","volume":"14","author":"Kiss","year":"2023","journal-title":"J. Cachex-.-. Sarcopenia Muscle"},{"key":"10.1016\/j.ecoenv.2024.117143_bib16","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.cger.2015.04.005","article-title":"Sarcopenia as the biological substrate of physical frailty","volume":"31","author":"Landi","year":"2015","journal-title":"Clin. Geriatr. Med"},{"key":"10.1016\/j.ecoenv.2024.117143_bib17","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1515\/reveh-2012-0012","article-title":"Effect of particulate matter air pollution on C-reactive protein: a review of epidemiologic studies","volume":"27","author":"Li","year":"2012","journal-title":"Rev. Environ. Health"},{"key":"10.1016\/j.ecoenv.2024.117143_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2024.141145","article-title":"Air pollution and risk of sarcopenia: a two-sample Mendelian randomized study","volume":"351","author":"Li","year":"2024","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2024.117143_bib19","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.ijcard.2011.05.054","article-title":"Subclinical atherosclerosis in a community-based elderly cohort: the Korean Longitudinal Study on Health and Aging","volume":"155","author":"Lim","year":"2012","journal-title":"Int J. Cardiol."},{"key":"10.1016\/j.ecoenv.2024.117143_bib20","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/s13395-024-00344-4","article-title":"Studying intramuscular fat deposition and muscle regeneration: insights from a comparative analysis of mouse strains, injury models, and sex differences","volume":"14","author":"Norris","year":"2024","journal-title":"Skelet. Muscle"},{"key":"10.1016\/j.ecoenv.2024.117143_bib21","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1161\/CIRCRESAHA.116.309279","article-title":"Exposure to fine particulate air pollution is associated with endothelial injury and systemic inflammation","volume":"119","author":"Pope","year":"2016","journal-title":"Circ. Res"},{"key":"10.1016\/j.ecoenv.2024.117143_bib22","doi-asserted-by":"crossref","first-page":"h1111","DOI":"10.1136\/bmj.h1111","article-title":"The relation between past exposure to fine particulate air pollution and prevalent anxiety: observational cohort study","volume":"350","author":"Power","year":"2015","journal-title":"Bmj"},{"key":"10.1016\/j.ecoenv.2024.117143_bib23","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.freeradbiomed.2016.02.021","article-title":"Redox control of skeletal muscle atrophy","volume":"98","author":"Powers","year":"2016","journal-title":"Free Radic. Biol. Med"},{"key":"10.1016\/j.ecoenv.2024.117143_bib24","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1089\/ars.2017.7394","article-title":"Effect of particulate matter air pollution on cardiovascular oxidative stress pathways","volume":"28","author":"Rao","year":"2018","journal-title":"Antioxid. Redox Signal"},{"key":"10.1016\/j.ecoenv.2024.117143_bib25","first-page":"422","article-title":"Mitochondrial quality control and muscle mass maintenance","volume":"6","author":"Romanello","year":"2015","journal-title":"Front Physiol."},{"key":"10.1016\/j.ecoenv.2024.117143_bib26","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.chest.2018.10.041","article-title":"Air pollution and noncommunicable diseases: a review by the forum of international respiratory societies' environmental committee, Part 2: air pollution and Organ Systems","volume":"155","author":"Schraufnagel","year":"2019","journal-title":"Chest"},{"key":"10.1016\/j.ecoenv.2024.117143_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2022.101617","article-title":"Sarcopenia definition: does it really matter? Implications for resistance training","volume":"78","author":"Smith","year":"2022","journal-title":"Ageing Res Rev."},{"key":"10.1016\/j.ecoenv.2024.117143_bib28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001779","article-title":"UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age","volume":"12","author":"Sudlow","year":"2015","journal-title":"PLoS Med"},{"key":"10.1016\/j.ecoenv.2024.117143_bib29","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1002\/jcsm.12462","article-title":"Physical function-derived cut-points for the diagnosis of sarcopenia and dynapenia from the Canadian longitudinal study on aging","volume":"10","author":"Tessier","year":"2019","journal-title":"J. Cachex-.-. Sarcopenia Muscle"},{"key":"10.1016\/j.ecoenv.2024.117143_bib30","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1385\/BTER:108:1-3:197","article-title":"Effects of cadmium and zinc on plasma levels of growth hormone, insulin-like growth factor I, and insulin-like growth factor-binding protein 3","volume":"108","author":"Turgut","year":"2005","journal-title":"Biol. Trace Elem. Res"},{"key":"10.1016\/j.ecoenv.2024.117143_bib31","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s12877-017-0700-4","volume":"18","author":"Villani","year":"2018","journal-title":"BMC Geriatr."},{"key":"10.1016\/j.ecoenv.2024.117143_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41435-022-00192-6","article-title":"Gene-environment interactions and their impact on human health","volume":"24","author":"Virolainen","year":"2023","journal-title":"Genes Immun."},{"key":"10.1016\/j.ecoenv.2024.117143_bib33","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1093\/eurheartj\/ehaa1031","article-title":"Joint exposure to various ambient air pollutants and incident heart failure: a prospective analysis in UK Biobank","volume":"42","author":"Wang","year":"2021","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ecoenv.2024.117143_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2024.116206","article-title":"Outdoor fine particulate matter exposure and telomere length in humans: a systematic review and meta-analysis","volume":"275","author":"Wei","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2024.117143_bib35","unstructured":"World Health Organization. Air quality guidelines global update 2005. https:\/\/www.who.int\/publications\/i\/item\/WHO-SDE-PHE-OEH-06.02, 2024 (Accessed June 17, 2024)."},{"key":"10.1016\/j.ecoenv.2024.117143_bib36","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1002\/jcsm.12411","article-title":"Sarcopenia and its association with falls and fractures in older adults: a systematic review and meta-analysis","volume":"10","author":"Yeung","year":"2019","journal-title":"J. Cachex-.-. Sarcopenia Muscle"},{"key":"10.1016\/j.ecoenv.2024.117143_bib37","doi-asserted-by":"crossref","first-page":"401","DOI":"10.5993\/AJHB.41.4.4","article-title":"Ambient fine particulate matter air pollution and physical activity: a longitudinal study of university retirees in Beijing, China","volume":"41","author":"Yu","year":"2017","journal-title":"Am. J. Health Behav."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651324012193?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651324012193?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T12:26:09Z","timestamp":1729081569000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651324012193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":37,"alternative-id":["S0147651324012193"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2024.117143","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exposure to air pollution, genetic susceptibility, and prevalence of sarcopenia in the UK","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2024.117143","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"117143"}}