{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T02:07:23Z","timestamp":1793844443934,"version":"4.6.1"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T00:00:00Z","timestamp":1730678400000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100017950","name":"Shanghai Municipal Health Commission","doi-asserted-by":"publisher","award":["202340113"],"award-info":[{"award-number":["202340113"]}],"id":[{"id":"10.13039\/100017950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019978","name":"Shanghai Pudong New Area Health Commission","doi-asserted-by":"publisher","award":["PW2023E-04"],"award-info":[{"award-number":["PW2023E-04"]}],"id":[{"id":"10.13039\/501100019978","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82371693"],"award-info":[{"award-number":["82371693"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.ecoenv.2024.117300","type":"journal-article","created":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T10:38:41Z","timestamp":1730889521000},"page":"117300","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":64,"special_numbering":"C","title":["Microplastics in maternal blood, fetal appendages, and umbilical vein blood"],"prefix":"10.1016","volume":"287","author":[{"given":"Hanxiang","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiujuan","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guohua","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiaoling","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2024.117300_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jenvman.2023.117720","article-title":"Prevalence of microplastics in commercially sold soft drinks and human risk assessment","volume":"336","author":"Altun\u0131\u015f\u0131k","year":"2023","journal-title":"J. Environ. Manag."},{"key":"10.1016\/j.ecoenv.2024.117300_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.120174","article-title":"Placental plastics in young women from general population correlate with reduced foetal growth in IUGR pregnancies","volume":"314","author":"Amereh","year":"2022","journal-title":"Environ. Pollut. (Barking, Essex: 1987)"},{"key":"10.1016\/j.ecoenv.2024.117300_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.129439","article-title":"First evidence of microplastics isolated in European citizens' lower airway","volume":"438","author":"Baeza-Mart\u00ednez","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2024.117300_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2022.118790","article-title":"Fate of microplastics in the drinking water production","volume":"221","author":"B\u00e4uerlein","year":"2022","journal-title":"Water Res."},{"key":"10.1016\/j.ecoenv.2024.117300_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2023.108015","article-title":"Transcriptomic profiling reveals differential cellular response to copper oxide nanoparticles and polystyrene nanoplastics in perfused human placenta","volume":"177","author":"Chortarea","year":"2023","journal-title":"Environ. Int."},{"key":"10.1016\/j.ecoenv.2024.117300_bib6","doi-asserted-by":"crossref","DOI":"10.3389\/ftox.2022.901798","article-title":"Developmental and reproductive toxic effects of exposure to microplastics: A review of associated signaling pathways","volume":"4","author":"Dubey","year":"2022","journal-title":"Front. Toxicol."},{"issue":"23","key":"10.1016\/j.ecoenv.2024.117300_bib7","doi-asserted-by":"crossref","first-page":"34594","DOI":"10.1007\/s11356-021-18218-3","article-title":"Exposure to microplastics leads to a defective ovarian function and change in cytoskeleton protein expression in rat","volume":"29","author":"Haddadi","year":"2022","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.ecoenv.2024.117300_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.140301","article-title":"Microplastics and additives in patients with preterm birth: The first evidence of their presence in both human amniotic fluid and placenta","volume":"343","author":"Halfar","year":"2023","journal-title":"Chemosphere"},{"issue":"3","key":"10.1016\/j.ecoenv.2024.117300_bib9","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1021\/acs.est.8b05297","article-title":"Are We Speaking the Same Language? Recommendations for a Definition and Categorization Framework for Plastic Debris","volume":"53","author":"Hartmann","year":"2019","journal-title":"Environ. Sci. Technol."},{"issue":"12","key":"10.1016\/j.ecoenv.2024.117300_bib10","doi-asserted-by":"crossref","first-page":"7036","DOI":"10.1021\/acs.est.7b01750","article-title":"Polyester Textiles as a Source of Microplastics from Households: A Mechanistic Study to Understand Microfiber Release During Washing","volume":"51","author":"Hernandez","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ecoenv.2024.117300_bib11","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.reprotox.2021.10.002","article-title":"Polystyrene microplastics disturb maternal-fetal immune balance and cause reproductive toxicity in pregnant mice","volume":"106","author":"Hu","year":"2021","journal-title":"Reprod. Toxicol. (Elmsford, NY)"},{"issue":"1","key":"10.1016\/j.ecoenv.2024.117300_bib12","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s12989-022-00453-2","article-title":"Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR\/cAMP\/PKA\/StAR pathway","volume":"19","author":"Jin","year":"2022","journal-title":"Part. Fibre Toxicol."},{"issue":"11","key":"10.1016\/j.ecoenv.2024.117300_bib13","doi-asserted-by":"crossref","first-page":"3502","DOI":"10.1080\/10408398.2022.2132212","article-title":"Food and human safety: the impact of microplastics","volume":"64","author":"Kadac-Czapska","year":"2024","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.ecoenv.2024.117300_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.166652","article-title":"Impacts of microplastic on fisheries and seafood security - Global analysis and synthesis","volume":"904","author":"Kibria","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2024.117300_bib15","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.watres.2019.02.054","article-title":"Microplastics in freshwaters and drinking water: Critical review and assessment of data quality","volume":"155","author":"Koelmans","year":"2019","journal-title":"Water Res."},{"issue":"Pt 2","key":"10.1016\/j.ecoenv.2024.117300_bib16","article-title":"Microplastic diagnostics in humans: \"The 3Ps\" Progress, problems, and prospects","volume":"856","author":"Kutralam-Muniasamy","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2024.117300_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107199","article-title":"Discovery and quantification of plastic particle pollution in human blood","volume":"163","author":"Leslie","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.ecoenv.2024.117300_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.117648","article-title":"Improved Raman spectroscopy-based approach to assess microplastics in seafood","volume":"289","author":"Leung","year":"2021","journal-title":"Environ. Pollut. (Barking, Essex: 1987)"},{"key":"10.1016\/j.ecoenv.2024.117300_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.132640","article-title":"Identification and analysis of microplastics in human lower limb joints","volume":"461","author":"Li","year":"2024","journal-title":"J. Hazard. Mater."},{"issue":"Pt 1","key":"10.1016\/j.ecoenv.2024.117300_bib20","article-title":"Current status of microplastics and nanoplastics removal methods: Summary, comparison and prospect","volume":"851","author":"Liu","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2024.117300_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.158699","article-title":"Detection of various microplastics in placentas, meconium, infant feces, breastmilk and infant formula: A pilot prospective study","volume":"854","author":"Liu","year":"2023","journal-title":"Sci. Total Environ."},{"issue":"46","key":"10.1016\/j.ecoenv.2024.117300_bib22","doi-asserted-by":"crossref","first-page":"17774","DOI":"10.1021\/acs.est.2c04706","article-title":"The Association Between Microplastics and Microbiota in Placentas and Meconium: The First Evidence in Humans","volume":"57","author":"Liu","year":"2023","journal-title":"Environ. Sci. Technol."},{"issue":"Pt C","key":"10.1016\/j.ecoenv.2024.117300_bib23","article-title":"Polystyrene microplastics induced female reproductive toxicity in mice","volume":"424","author":"Liu","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2024.117300_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.133976","article-title":"Extraction, identification, and environmental risk assessment of microplastics in commercial toothpaste","volume":"296","author":"Madhumitha","year":"2022","journal-title":"Chemosphere"},{"issue":"1-2","key":"10.1016\/j.ecoenv.2024.117300_bib25","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.marpolbul.2015.07.029","article-title":"Characterisation, quantity and sorptive properties of microplastics extracted from cosmetics","volume":"99","author":"Napper","year":"2015","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.ecoenv.2024.117300_bib26","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.envpol.2017.11.043","article-title":"Airborne microplastics: Consequences to human health?","volume":"234","author":"Prata","year":"2018","journal-title":"Environ. Pollut. (Barking, Essex: 1987)"},{"issue":"24","key":"10.1016\/j.ecoenv.2024.117300_bib27","doi-asserted-by":"crossref","first-page":"10482","DOI":"10.1021\/acs.est.4c01541","article-title":"Features, Potential Invasion Pathways, and Reproductive Health Risks of Microplastics Detected in Human Uterus","volume":"58","author":"Qin","year":"2024","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ecoenv.2024.117300_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.106274","article-title":"Plasticenta: First evidence of microplastics in human placenta","volume":"146","author":"Ragusa","year":"2021","journal-title":"Environ. Int."},{"issue":"13","key":"10.1016\/j.ecoenv.2024.117300_bib29","doi-asserted-by":"crossref","DOI":"10.3390\/polym14132700","article-title":"Raman Microspectroscopy Detection and Characterisation of Microplastics in Human Breastmilk","volume":"14","author":"Ragusa","year":"2022","journal-title":"Polymers"},{"key":"10.1016\/j.ecoenv.2024.117300_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.120747","article-title":"Microplastics and plastics-associated contaminants in food and beverages; Global trends, concentrations, and human exposure","volume":"317","author":"Sewwandi","year":"2023","journal-title":"Environ. Pollut. (Barking, Essex: 1987)"},{"key":"10.1016\/j.ecoenv.2024.117300_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2022.118960","article-title":"Mechanistic toxicity assessment of differently sized and charged polystyrene nanoparticles based on human placental cells","volume":"223","author":"Shen","year":"2022","journal-title":"Water Res."},{"key":"10.1016\/j.ecoenv.2024.117300_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.167760","article-title":"Detection and quantification of various microplastics in human endometrium based on laser direct infrared spectroscopy","volume":"906","author":"Sun","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2024.117300_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.155275","article-title":"Micro- and nanoplastics released from biodegradable and conventional plastics during degradation: Formation, aging factors, and toxicity","volume":"833","author":"Tong","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2024.117300_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2021.153059","article-title":"Comparing the effects of polystyrene microplastics exposure on reproduction and fertility in male and female mice","volume":"465","author":"Wei","year":"2022","journal-title":"Toxicology"},{"key":"10.1016\/j.ecoenv.2024.117300_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.171044","article-title":"Microplastics in maternal amniotic fluid and their associations with gestational age","volume":"920","author":"Xue","year":"2024","journal-title":"Sci. Total Environ."},{"issue":"30","key":"10.1016\/j.ecoenv.2024.117300_bib36","doi-asserted-by":"crossref","first-page":"10911","DOI":"10.1021\/acs.est.2c07179","article-title":"Detection of Various Microplastics in Patients Undergoing Cardiac Surgery","volume":"57","author":"Yang","year":"2023","journal-title":"Environ. Sci. Technol."},{"issue":"7","key":"10.1016\/j.ecoenv.2024.117300_bib37","doi-asserted-by":"crossref","first-page":"3740","DOI":"10.1021\/acs.est.9b04535","article-title":"A Review of Microplastics in Table Salt, Drinking Water, and Air: Direct Human Exposure","volume":"54","author":"Zhang","year":"2020","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ecoenv.2024.117300_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.121482","article-title":"Reproductive toxicity of microplastics in female mice and their offspring from induction of oxidative stress","volume":"327","author":"Zhang","year":"2023","journal-title":"Environ. Pollut. (Barking, Essex: 1987)"},{"key":"10.1016\/j.ecoenv.2024.117300_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.162713","article-title":"Detection and characterization of microplastics in the human testis and semen","volume":"877","author":"Zhao","year":"2023","journal-title":"Sci. Total Environ."},{"issue":"Pt 1","key":"10.1016\/j.ecoenv.2024.117300_bib40","article-title":"Identification of microplastics in human placenta using laser direct infrared spectroscopy","volume":"856","author":"Zhu","year":"2023","journal-title":"Sci. Total Environ."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651324013769?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651324013769?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T08:41:49Z","timestamp":1762245709000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651324013769"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":40,"alternative-id":["S0147651324013769"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2024.117300","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Microplastics in maternal blood, fetal appendages, and umbilical vein blood","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2024.117300","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"117300"}}