{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T17:48:45Z","timestamp":1793900925878,"version":"4.8.0"},"reference-count":85,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T00:00:00Z","timestamp":1732060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.ecoenv.2024.117395","type":"journal-article","created":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T04:55:59Z","timestamp":1732683359000},"page":"117395","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Kidney function mediates the effects of four per-and polyfluoroalkyl substances (PFAS) on atherosclerotic cardiovascular disease"],"prefix":"10.1016","volume":"288","author":[{"given":"Zhengqi","family":"Wei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keke","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Ying","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyue","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ecoenv.2024.117395_bib1","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1038\/s41561-024-01402-8","article-title":"Underestimated burden of per- and polyfluoroalkyl substances in global surface waters and groundwaters","volume":"17","author":"Ackerman Grunfeld","year":"2024","journal-title":"Nat. Geosci."},{"key":"10.1016\/j.ecoenv.2024.117395_bib2","doi-asserted-by":"crossref","DOI":"10.1093\/eurjpc\/zwae254","article-title":"In-silico trial emulation to predict the cardiovascular protection of new lipid-lowering drugs: an illustration through the design of the SIRIUS programme","author":"Angoulvant","year":"2024","journal-title":"Eur. J. Prev. Cardiol."},{"issue":"11","key":"10.1016\/j.ecoenv.2024.117395_bib3","first-page":"e596","article-title":"2019 ACC\/AHA guideline on the primary prevention of cardiovascular disease: a report of the american college of cardiology\/american heart association task force on clinical practice guidelines","volume":"140","author":"Arnett","year":"2019","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.ecoenv.2024.117395_bib4","doi-asserted-by":"crossref","first-page":"27002","DOI":"10.1289\/EHP13152","article-title":"Determinants of PFOA serum half-life after end of exposure: a longitudinal study on highly exposed subjects in the veneto region","volume":"132","author":"Batzella","year":"2024","journal-title":"Environ. Health Perspect."},{"issue":"1","key":"10.1016\/j.ecoenv.2024.117395_bib5","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s12940-024-01074-2","article-title":"All-cause, cardiovascular disease and cancer mortality in the population of a large Italian area contaminated by perfluoroalkyl and polyfluoroalkyl substances (1980-2018)","volume":"23","author":"Biggeri","year":"2024","journal-title":"Environ. Health.: a Glob. Access Sci. Source"},{"issue":"7","key":"10.1016\/j.ecoenv.2024.117395_bib6","doi-asserted-by":"crossref","first-page":"77005","DOI":"10.1289\/EHP10009","article-title":"Internal relative potency factors for the risk assessment of mixtures of per- and polyfluoroalkyl substances (PFAS) in human biomonitoring","volume":"130","author":"Bil","year":"2022","journal-title":"Environ. Health Perspect."},{"issue":"2","key":"10.1016\/j.ecoenv.2024.117395_bib7","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1007\/s40572-024-00441-y","article-title":"Public health risks of PFAS-related immunotoxicity are real","volume":"11","author":"Bline","year":"2024","journal-title":"Curr. Environ. Health Rep."},{"issue":"12","key":"10.1016\/j.ecoenv.2024.117395_bib8","doi-asserted-by":"crossref","DOI":"10.3390\/toxics11120979","article-title":"Association of combined metals and PFAS with cardiovascular disease risk","volume":"11","author":"Boafo","year":"2023","journal-title":"Toxics"},{"key":"10.1016\/j.ecoenv.2024.117395_bib9","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2022.873452","article-title":"Editorial: immunomodulatory approaches in cardiovascular diseases","volume":"9","author":"Booz","year":"2022","journal-title":"Front. Cardiovasc. Med."},{"issue":"8s","key":"10.1016\/j.ecoenv.2024.117395_bib10","article-title":"Dyslipidemia and the current state of cardiovascular disease: epidemiology, risk factors, and effect of lipid lowering","volume":"40","author":"Brunham","year":"2024","journal-title":"Can. J. Cardiol."},{"issue":"5","key":"10.1016\/j.ecoenv.2024.117395_bib11","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1124\/dmd.119.089755","article-title":"Ontogeny and cross-species comparison of pathways involved in drug absorption, distribution, metabolism, and excretion in neonates (review): kidney","volume":"48","author":"Bueters","year":"2020","journal-title":"Drug Metab. Dispos.: Biol. fate Chem."},{"key":"10.1016\/j.ecoenv.2024.117395_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.115812","article-title":"Exploring the association between two groups of metals with potentially opposing renal effects and renal function in middle-aged and older adults: evidence from an explainable machine learning method","volume":"269","author":"Chen","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"7","key":"10.1016\/j.ecoenv.2024.117395_bib13","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2024.22558","article-title":"Low-density lipoprotein cholesterol, cardiovascular disease risk, and mortality in China","volume":"7","author":"Chen","year":"2024","journal-title":"JAMA Netw. Open"},{"issue":"5","key":"10.1016\/j.ecoenv.2024.117395_bib14","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1038\/s41370-023-00536-y","article-title":"Occupational exposure to per- and polyfluoroalkyl substances: a scope review of the literature from 1980\u20132021","volume":"33","author":"Christensen","year":"2023","journal-title":"J. Expo. Sci. Environ. Epidemiol."},{"issue":"Pt 2","key":"10.1016\/j.ecoenv.2024.117395_bib15","article-title":"Factors associated with per- and polyfluoroalkyl substances (PFAS) serum concentrations in residents of New Hanover County, North Carolina: the GenX exposure study","volume":"237","author":"Cuffney","year":"2023","journal-title":"Environ. Res"},{"issue":"2","key":"10.1016\/j.ecoenv.2024.117395_bib16","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21020399","article-title":"Increased cardiovascular risk associated with chemical sensitivity to perfluoro-octanoic acid: role of impaired platelet aggregation","volume":"21","author":"De Toni","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.ecoenv.2024.117395_bib17","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1053\/j.ajkd.2021.08.003","article-title":"A unifying approach for GFR estimation: recommendations of the NKF-ASN task force on reassessing the inclusion of race in diagnosing kidney disease","volume":"79","author":"Delgado","year":"2022","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.ecoenv.2024.117395_bib18","doi-asserted-by":"crossref","DOI":"10.1001\/jama.2024.12537","article-title":"Projected changes in statin and antihypertensive therapy eligibility with the AHA PREVENT cardiovascular risk equations","author":"Diao","year":"2024","journal-title":"Jama"},{"key":"10.1016\/j.ecoenv.2024.117395_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2023.108250","article-title":"Plasma levels of per- and polyfluoroalkyl substances (PFAS) and cardiovascular disease - results from two independent population-based cohorts and a meta-analysis","volume":"181","author":"Dunder","year":"2023","journal-title":"Environ. Int"},{"issue":"2","key":"10.1016\/j.ecoenv.2024.117395_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/toxics11020163","article-title":"A scoping assessment of implemented toxicokinetic models of per- and polyfluoro-alkyl substances, with a focus on one-compartment models","volume":"11","author":"East","year":"2023","journal-title":"Toxics"},{"key":"10.1016\/j.ecoenv.2024.117395_bib21","doi-asserted-by":"crossref","DOI":"10.1053\/j.ajkd.2024.02.008","article-title":"Klotho and clinical outcomes in CKD: findings from the chronic renal insufficiency cohort (CRIC) study","author":"Edmonston","year":"2024","journal-title":"Am. J. Kidney Dis.: Off. J. Natl. Kidney Found."},{"issue":"2","key":"10.1016\/j.ecoenv.2024.117395_bib22","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1021\/acs.est.3c07415","article-title":"Binding of per- and polyfluoroalkyl substances (PFAS) to serum proteins: implications for toxicokinetics in humans","volume":"58","author":"Fischer","year":"2024","journal-title":"Environ. Sci. Technol."},{"issue":"2","key":"10.1016\/j.ecoenv.2024.117395_bib23","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1161\/HYPERTENSIONAHA.119.14240","article-title":"High blood pressure and cardiovascular Disease","volume":"75","author":"Fuchs","year":"2020","journal-title":"Hypertens. (Dallas, Tex: 1979)"},{"issue":"43","key":"10.1016\/j.ecoenv.2024.117395_bib24","doi-asserted-by":"crossref","first-page":"16244","DOI":"10.1021\/acs.est.3c06480","article-title":"Novel insights into the adverse health effects of per- and polyfluoroalkyl substances on the kidney via human urine metabolomics","volume":"57","author":"He","year":"2023","journal-title":"Environ. Sci. Technol."},{"issue":"1","key":"10.1016\/j.ecoenv.2024.117395_bib25","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1186\/s12916-024-03316-z","article-title":"The role of lifestyle in the association between long-term ambient air pollution exposure and cardiovascular disease: a national cohort study in China","volume":"22","author":"Hu","year":"2024","journal-title":"BMC Med."},{"issue":"1","key":"10.1016\/j.ecoenv.2024.117395_bib26","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1186\/s12933-023-01839-y","article-title":"The atherogenic index of plasma and carotid atherosclerosis in a community population: a population-based cohort study in China","volume":"22","author":"Huang","year":"2023","journal-title":"Cardiovasc. Diabetol."},{"key":"10.1016\/j.ecoenv.2024.117395_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.jad.2024.05.119","article-title":"The impact of depression-mediated gut microbiota composition on irritable bowel syndrome: A Mendelian study","author":"Huang","year":"2024","journal-title":"J. Affect Disord."},{"issue":"13","key":"10.1016\/j.ecoenv.2024.117395_bib28","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1016\/j.jacc.2023.07.012","article-title":"Impaired renal function and major cardiovascular events in young adults","volume":"82","author":"Hussain","year":"2023","journal-title":"J. Am. Coll. Cardiol."},{"issue":"3","key":"10.1016\/j.ecoenv.2024.117395_bib29","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1007\/s40726-023-00269-4","article-title":"PFAS exposures and the human metabolome: a systematic review of epidemiological studies","volume":"9","author":"India-Aldana","year":"2023","journal-title":"Curr. Pollut. Rep."},{"key":"10.1016\/j.ecoenv.2024.117395_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/S2213-8587(24)00192-X","article-title":"Long-term sex differences in atherosclerotic cardiovascular disease in individuals with heterozygous familial hypercholesterolaemia in Spain: a study using data from SAFEHEART, a nationwide, multicentre, prospective cohort study","author":"de Isla","year":"2024","journal-title":"Lancet Diabetes Endocrinol."},{"issue":"Pt C","key":"10.1016\/j.ecoenv.2024.117395_bib31","article-title":"Health-related toxicity of emerging per- and polyfluoroalkyl substances: comparison to legacy PFOS and PFOA","volume":"212","author":"Jane","year":"2022","journal-title":"Environ. Res"},{"issue":"9","key":"10.1016\/j.ecoenv.2024.117395_bib32","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s11886-021-01546-8","article-title":"Intersection between chronic kidney disease and cardiovascular disease","volume":"23","author":"Laffin","year":"2021","journal-title":"Curr. Cardiol. Rep."},{"issue":"4","key":"10.1016\/j.ecoenv.2024.117395_bib33","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1177\/2047487319869400","article-title":"Lifestyle factors and high-risk atherosclerosis: pathways and mechanisms beyond traditional risk factors","volume":"27","author":"Lechner","year":"2020","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.ecoenv.2024.117395_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.137464","article-title":"Association of exposure to perfluoroalkyl substances and risk of the acute coronary syndrome: a case-control study in Shijiazhuang Hebei Province","volume":"313","author":"Li","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2024.117395_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.157165","article-title":"Exposure to various ambient air pollutants increases the risk of venous thromboembolism: a cohort study in UK Biobank","volume":"845","author":"Li","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"12","key":"10.1016\/j.ecoenv.2024.117395_bib36","doi-asserted-by":"crossref","first-page":"e672","DOI":"10.1016\/S2468-2667(20)30191-2","article-title":"Cardiovascular risk factors in China: a nationwide population-based cohort study","volume":"5","author":"Li","year":"2020","journal-title":"Lancet Public Health"},{"key":"10.1016\/j.ecoenv.2024.117395_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2024.116524","article-title":"Association of co-exposure to organophosphate esters and per- and polyfluoroalkyl substances and mixture with cardiovascular-kidney-liver-metabolic biomarkers among Chinese adults","volume":"280","author":"Li","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"1","key":"10.1016\/j.ecoenv.2024.117395_bib38","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1186\/s12916-024-03527-4","article-title":"Comparative analysis of atherosclerotic cardiovascular disease burden between ages 20-54 and over 55 years: insights from the Global Burden of Disease Study 2019","volume":"22","author":"Li","year":"2024","journal-title":"BMC Med."},{"issue":"17","key":"10.1016\/j.ecoenv.2024.117395_bib39","doi-asserted-by":"crossref","first-page":"6825","DOI":"10.1021\/acs.est.2c05642","article-title":"Mechanistic middle-out physiologically based toxicokinetic modeling of transporter-dependent disposition of perfluorooctanoic acid in humans","volume":"57","author":"Lin","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ecoenv.2024.117395_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.106375","article-title":"Per- and polyfluoroalkyl substances and kidney function: follow-up results from the Diabetes Prevention Program trial","volume":"148","author":"Lin","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.ecoenv.2024.117395_bib41","article-title":"Perfluorooctanoic acid (PFOA) exposure in relation to the kidneys: a review of current available literature","volume":"14","author":"Liu","year":"2023","journal-title":"Front. Physiol."},{"issue":"7","key":"10.1016\/j.ecoenv.2024.117395_bib42","doi-asserted-by":"crossref","DOI":"10.1093\/ageing\/afae161","article-title":"Associations of 10-year atherosclerotic cardiovascular disease risk scores with cerebral small vessel disease: the PolyvasculaR evaluation for cognitive impairment and vaScular events (PRECISE) study","volume":"53","author":"Liu","year":"2024","journal-title":"Age Ageing"},{"issue":"1","key":"10.1016\/j.ecoenv.2024.117395_bib43","doi-asserted-by":"crossref","first-page":"8002","DOI":"10.1038\/s41598-024-58678-4","article-title":"Blood urea nitrogen to serum albumin ratio as a new prognostic indicator in type 2 diabetes mellitus patients with chronic kidney disease","volume":"14","author":"Liu","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ecoenv.2024.117395_bib44","article-title":"Association between cardiovascular health and retinopathy in US adults: from NHANES 2005-2008","author":"Liu","year":"2024","journal-title":"Am. J. Ophthalmol."},{"issue":"2","key":"10.1016\/j.ecoenv.2024.117395_bib45","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1080\/10643389.2023.2223118","article-title":"A critical review on the bioaccumulation, transportation, and elimination of per- and polyfluoroalkyl substances in human beings","volume":"54","author":"Lu","year":"2024","journal-title":"Crit. Rev. Environ. Sci. Technol."},{"key":"10.1016\/j.ecoenv.2024.117395_bib46","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1265\/ehpm.24-00047","article-title":"Is Japan at low risk for PFAS immunotoxicity?: human biomonitoring study in contaminated areas in Japan","volume":"29","author":"Lyu","year":"2024","journal-title":"Environ. Health Prev. Med."},{"issue":"14","key":"10.1016\/j.ecoenv.2024.117395_bib47","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1056\/NEJMoa2206916","article-title":"Global effect of modifiable risk factors on cardiovascular disease and mortality","volume":"389","author":"Magnussen","year":"2023","journal-title":"N. Engl. J. Med."},{"issue":"9","key":"10.1016\/j.ecoenv.2024.117395_bib48","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1016\/j.ekir.2023.07.002","article-title":"Environmental change, changing biodiversity, and infections\u2013lessons for kidney health community","volume":"8","author":"Meena","year":"2023","journal-title":"Kidney Int. Rep."},{"key":"10.1016\/j.ecoenv.2024.117395_bib49","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.706352","article-title":"Exposure to perfluoroalkyl chemicals and cardiovascular disease: experimental and epidemiological evidence","volume":"12","author":"Meneguzzi","year":"2021","journal-title":"Front. Endocrinol."},{"issue":"1","key":"10.1016\/j.ecoenv.2024.117395_bib50","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1021\/acs.est.3c06499","article-title":"Occurrence of major perfluorinated alkylate substances in human blood and target organs","volume":"58","author":"Nielsen","year":"2024","journal-title":"Environ. Sci. Technol."},{"issue":"6","key":"10.1016\/j.ecoenv.2024.117395_bib51","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.jacbts.2023.12.007","article-title":"Costimulatory and coinhibitory immune checkpoints in atherosclerosis: therapeutic targets in atherosclerosis?","volume":"9","author":"Nitz","year":"2024","journal-title":"JACC Basic Transl. Sci."},{"issue":"7","key":"10.1016\/j.ecoenv.2024.117395_bib52","doi-asserted-by":"crossref","first-page":"76002","DOI":"10.1289\/EHP11885","article-title":"A state-of-the-science review of interactions of per- and polyfluoroalkyl substances (PFAS) with renal transporters in health and disease: implications for population variability in PFAS toxicokinetics","volume":"131","author":"Niu","year":"2023","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ecoenv.2024.117395_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.134312","article-title":"Kidney function decline mediates the adverse effects of per- and poly-fluoroalkyl substances (PFAS) on uric acid levels and hyperuricemia risk","volume":"471","author":"Niu","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2024.117395_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106446","article-title":"Per- and polyfluoroalkyl substances and calcifications of the coronary and aortic arteries in adults with prediabetes: results from the diabetes prevention program outcomes study","volume":"151","author":"Osorio-Y\u00e1\u00f1ez","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.ecoenv.2024.117395_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.135269","article-title":"Comparative toxicity assessment of alternative versus legacy PFAS: implications for two primary trophic levels in freshwater ecosystems","volume":"477","author":"Pietropoli","year":"2024","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.ecoenv.2024.117395_bib56","doi-asserted-by":"crossref","DOI":"10.1161\/ATVBAHA.124.320902","article-title":"Thrombin generation is associated with extracellular vesicle and leukocyte lipid membranes in atherosclerotic cardiovascular disease","author":"Protty","year":"2024","journal-title":"Arterioscl. Thromb. Vascul. Biol."},{"key":"10.1016\/j.ecoenv.2024.117395_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.122686","article-title":"Toxic ties: unraveling the complex relationship between endocrine disrupting chemicals and chronic kidney disease","volume":"338","author":"Ramya Ranjan Nayak","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2024.117395_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2023.117743","article-title":"Estimation of per- and polyfluoroalkyl substances (PFAS) half-lives in human studies: a systematic review and meta-analysis","volume":"242","author":"Rosato","year":"2024","journal-title":"Environ. Res."},{"key":"10.1016\/j.ecoenv.2024.117395_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.115164","article-title":"Perfluoroalkyl substances exposure in firefighters: sources and implications","volume":"220","author":"Rosenfeld","year":"2023","journal-title":"Environ. Res"},{"key":"10.1016\/j.ecoenv.2024.117395_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2024.142390","article-title":"Evaluation of 14 PFAS for permeability and organic anion transporter interactions: implications for renal clearance in humans","volume":"361","author":"Ryu","year":"2024","journal-title":"Chemosphere"},{"issue":"2","key":"10.1016\/j.ecoenv.2024.117395_bib61","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1021\/acs.est.3c06388","article-title":"OMICs signatures linking persistent organic pollutants to cardiovascular disease in the swedish mammography cohort","volume":"58","author":"Schillemans","year":"2024","journal-title":"Environ. Sci. Technol."},{"issue":"9","key":"10.1016\/j.ecoenv.2024.117395_bib62","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1161\/CIRCRESAHA.124.323697","article-title":"Perfluoroalkyl\/polyfluoroalkyl substances: links to cardiovascular disease risk","volume":"134","author":"Schlezinger","year":"2024","journal-title":"Circ. Res."},{"key":"10.1016\/j.ecoenv.2024.117395_bib63","doi-asserted-by":"crossref","DOI":"10.1039\/D4EM00159A","article-title":"Comprehensive assessment of per and polyfluoroalkyl substances (PFAS) contamination in groundwater of Kamrup, Assam, India: occurrence, health risks, and metabolomic insights","author":"Sharma","year":"2024","journal-title":"Environ. Sci. Process. Impacts"},{"key":"10.1016\/j.ecoenv.2024.117395_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajpc.2020.100106","article-title":"Top 10 dietary strategies for atherosclerotic cardiovascular risk reduction","volume":"4","author":"Sikand","year":"2020","journal-title":"Am. J. Prev. Cardiol."},{"key":"10.1016\/j.ecoenv.2024.117395_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2023.115424","article-title":"Short-chain per- and polyfluoralkyl substances (PFAS) effects on oxidative stress biomarkers in human liver, kidney, muscle, and microglia cell lines","volume":"223","author":"Solan","year":"2023","journal-title":"Environ. Res"},{"issue":"10","key":"10.1016\/j.ecoenv.2024.117395_bib66","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.2215\/CJN.04670418","article-title":"Perfluorinated chemicals as emerging environmental threats to kidney health: a scoping review","volume":"13","author":"Stanifer","year":"2018","journal-title":"Clin. J. Am. Soc. Nephrol.: CJASN"},{"issue":"8","key":"10.1016\/j.ecoenv.2024.117395_bib67","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.jacc.2021.12.016","article-title":"Managing atherosclerotic cardiovascular risk in young adults","volume":"79","author":"Stone","year":"2022","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ecoenv.2024.117395_bib68","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.156299","article-title":"Co-exposure to perfluoroalkyl acids and heavy metals mixtures associated with impaired kidney function in adults: a community-based population study in China","volume":"839","author":"Su","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"1","key":"10.1016\/j.ecoenv.2024.117395_bib69","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/s41392-020-00455-6","article-title":"A double-edged sword of immuno-microenvironment in cardiac homeostasis and injury repair","volume":"6","author":"Sun","year":"2021","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.ecoenv.2024.117395_bib70","article-title":"Role of symbiotic microbiota dysbiosis in the progression of chronic kidney disease accompanied with vascular calcification","volume":"14","author":"Sun","year":"2023","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.ecoenv.2024.117395_bib71","article-title":"One-size-fits-all versus risk-category-based screening interval strategies for cardiovascular disease prevention in Chinese adults: a prospective cohort study","volume":"49","author":"Sun","year":"2024","journal-title":"Lancet Reg. Health West. Pac."},{"key":"10.1016\/j.ecoenv.2024.117395_bib72","doi-asserted-by":"crossref","DOI":"10.1016\/j.yrtph.2021.105099","article-title":"Physiologically based pharmacokinetic (PBPK) modeling of perfluorohexane sulfonate (PFHxS) in humans","volume":"129","author":"Sweeney","year":"2022","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.ecoenv.2024.117395_bib73","doi-asserted-by":"crossref","DOI":"10.1093\/eurjpc\/zwae204","article-title":"Cardiovascular Risk in Cancer Patients Treated with Immune Checkpoint Inhibitors: Challenges and Future Directions","author":"Tan","year":"2024","journal-title":"Eur. J. Prev. Cardiol."},{"issue":"14","key":"10.1016\/j.ecoenv.2024.117395_bib74","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1161\/CIRCULATIONAHA.119.044282","article-title":"Secondary prevention for atherosclerotic cardiovascular disease","volume":"141","author":"Virani","year":"2020","journal-title":"Circulation"},{"key":"10.1016\/j.ecoenv.2024.117395_bib75","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.115663","article-title":"Environmental impacts, exposure pathways, and health effects of PFOA and PFOS","volume":"267","author":"Wee","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"Pt 2","key":"10.1016\/j.ecoenv.2024.117395_bib76","article-title":"Kidney function mediates the association of per- and poly-fluoroalkyl substances (PFAS) and heavy metals with hepatic fibrosis risk","volume":"263","author":"Wei","year":"2024","journal-title":"Environ. Res"},{"issue":"5","key":"10.1016\/j.ecoenv.2024.117395_bib77","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1007\/s00204-023-03477-5","article-title":"A review of cardiovascular effects and underlying mechanisms of legacy and emerging per- and polyfluoroalkyl substances (PFAS)","volume":"97","author":"Wen","year":"2023","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.ecoenv.2024.117395_bib78","doi-asserted-by":"crossref","DOI":"10.1016\/j.mayocp.2024.03.025","article-title":"Effects of inclisiran in patients with atherosclerotic cardiovascular disease: a pooled analysis of the ORION-10 and ORION-11 randomized trials","author":"Wright","year":"2024","journal-title":"Mayo Clin. Proc."},{"key":"10.1016\/j.ecoenv.2024.117395_bib79","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.167945","article-title":"Dietary exposure to per- and polyfluoroalkyl substances: potential health impacts on human liver","volume":"907","author":"Zhang","year":"2024","journal-title":"Sci. Total Environ."},{"issue":"1","key":"10.1016\/j.ecoenv.2024.117395_bib80","doi-asserted-by":"crossref","first-page":"17008","DOI":"10.1289\/EHP10967","article-title":"Exposure to air pollution during pre-hypertension and subsequent hypertension, cardiovascular disease, and death: a trajectory analysis of the UK Biobank Cohort","volume":"131","author":"Zhang","year":"2023","journal-title":"Environ. Health Perspect."},{"issue":"25","key":"10.1016\/j.ecoenv.2024.117395_bib81","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1161\/CIRCULATIONAHA.123.065506","article-title":"Targeting NPM1 epigenetically promotes postinfarction cardiac repair by reprogramming reparative macrophage metabolism","volume":"149","author":"Zhang","year":"2024","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.ecoenv.2024.117395_bib82","article-title":"Association of per- and polyfluoroalkyl substance exposure with fatty liver disease risk in US adults","volume":"5","author":"Zhang","year":"2023","journal-title":"JHEP Rep.: Innov. Hepatol."},{"issue":"4","key":"10.1016\/j.ecoenv.2024.117395_bib83","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1016\/j.numecd.2021.11.007","article-title":"Association between estimated glomerular filtration rate and 10-year atherosclerotic cardiovascular disease risk among community residents in Shanghai, China","volume":"32","author":"Zhang","year":"2022","journal-title":"Nutr., Metab. Cardiovasc. Dis."},{"key":"10.1016\/j.ecoenv.2024.117395_bib84","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.175139","article-title":"PFOS impairs cardiac function and energy metabolism under high-fat diet: insights into role of circulating macrophage emphasized by exposure distribution","volume":"949","author":"Zhang","year":"2024","journal-title":"Sci. Total Environ."},{"issue":"11","key":"10.1016\/j.ecoenv.2024.117395_bib85","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1093\/cvr\/cvad083","article-title":"Cardiovascular complications in chronic kidney disease: a review from the European renal and cardiovascular medicine working group of the European renal association","volume":"119","author":"Zoccali","year":"2023","journal-title":"Cardiovasc. Res."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651324014714?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651324014714?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,19]],"date-time":"2025-01-19T15:23:16Z","timestamp":1737300196000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651324014714"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":85,"alternative-id":["S0147651324014714"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2024.117395","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Kidney function mediates the effects of four per-and polyfluoroalkyl substances (PFAS) on atherosclerotic cardiovascular disease","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2024.117395","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"117395"}}