{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T14:10:29Z","timestamp":1784297429910,"version":"3.55.0"},"reference-count":79,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,28]],"date-time":"2024-12-28T00:00:00Z","timestamp":1735344000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFD2401002"],"award-info":[{"award-number":["2023YFD2401002"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.ecoenv.2024.117635","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T11:22:02Z","timestamp":1735644122000},"page":"117635","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Application of the DEB-TKTD model with multi-omics data: Prediction of life history traits of Chinese mitten crab (Eriocheir sinensis) under different salinities"],"prefix":"10.1016","volume":"290","author":[{"given":"Hanzun","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shipeng","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwei","family":"Shan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2024.117635_bib1","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.seares.2011.09.005","article-title":"The AquaDEB project: physiological flexibility of aquatic animals analysed with a generic dynamic energy budget model (phase II)","volume":"66","author":"Alunno-Bruscia","year":"2011","journal-title":"J. Sea Res."},{"key":"10.1016\/j.ecoenv.2024.117635_bib2","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1890\/14-0498.1","article-title":"Relating suborganismal processes to ecotoxicological and population level endpoints using a bioenergetic model","volume":"25","author":"Ananthasubramaniam","year":"2015","journal-title":"Ecol. Appl."},{"key":"10.1016\/j.ecoenv.2024.117635_bib3","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1002\/etc.34","article-title":"Adverse outcome pathways: a conceptual framework to support ecotoxicology research and risk assessment","volume":"29","author":"Ankley","year":"2009","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.ecoenv.2024.117635_bib4","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1039\/C7EM00328E","article-title":"Physiological modes of action across species and toxicants: the key to predictive ecotoxicology","volume":"20","author":"Ashauer","year":"2018","journal-title":"Environ. Sci. Process Impacts"},{"key":"10.1016\/j.ecoenv.2024.117635_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpc.2020.108971","article-title":"Modulation of physiological oxidative stress and antioxidant status by abiotic factors especially salinity in aquatic organisms","volume":"241","author":"Bal","year":"2021","journal-title":"Comp. Biochem. Physiol. Part C Toxicol. Pharmacol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.114499","article-title":"Modelling the effects of the pyrethroid insecticide cypermethrin on the life cycle of the soil dwelling annelid Enchytraeus crypticus, an original experimental design to calibrate a DEB-TKTD model","volume":"250","author":"Bart","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2024.117635_bib7","first-page":"289","article-title":"Beyond metabolomics: a review of multi-omics-based approaches","author":"Beale","year":"2016","journal-title":"Microb. Metab. Appl. Clin., Environ.\u00a0Ind. Microbiol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib8","doi-asserted-by":"crossref","first-page":"2252","DOI":"10.1002\/etc.5620211032","article-title":"Modeling explicitly and mechanistically median lethal concentration as a function of time for risk assessment","volume":"21","author":"Bonnomet","year":"2009","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.ecoenv.2024.117635_bib9","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s00204-020-02656-y","article-title":"Prospects and challenges of multi-omics data integration in toxicology","volume":"94","author":"Canzler","year":"2020","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib10","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.aquaculture.2016.11.025","article-title":"Reproductive performance, offspring quality, proximate and fatty acid composition of normal and precocious Chinese mitten crab Eriocheir sinensis","volume":"469","author":"Chang","year":"2017","journal-title":"Aquaculture"},{"key":"10.1016\/j.ecoenv.2024.117635_bib11","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1111\/1365-2435.12009","article-title":"Life history and the ecology of stress: how do glucocorticoid hormones influence life-history variation in animals?","volume":"27","author":"Crespi","year":"2012","journal-title":"Funct. Ecol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib12","series-title":"Research Developments in Saline Agriculture","author":"Dagar","year":"2019"},{"key":"10.1016\/j.ecoenv.2024.117635_bib13","article-title":"Comparative transcriptome analysis reveals osmotic-regulated genes in the gill of Chinese mitten crab (Eriocheir sinensis)","volume":"14","author":"Dahms","year":"2019","journal-title":"Plos One"},{"key":"10.1016\/j.ecoenv.2024.117635_bib14","doi-asserted-by":"crossref","DOI":"10.3389\/fmars.2022.918449","article-title":"A siscontinuous individual growth model of swimming crab Portunus trituberculatus and its application in the nutrient dynamic simulation in an intensive mariculture pond","volume":"9","author":"Dong","year":"2022","journal-title":"Front. Mar. Sci."},{"key":"10.1016\/j.ecoenv.2024.117635_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.168408","article-title":"Practice assessment of integrated marine pond aquaculture for increasing benefits and reducing environmental pollution using an ecosystem modeling approach","volume":"908","author":"Dong","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2024.117635_bib16","series-title":"Aquaculture Ecology","first-page":"403","article-title":"Pond aquaculture in waterlogged salt-alkali land","author":"Dong","year":"2023"},{"key":"10.1016\/j.ecoenv.2024.117635_bib17","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.3390\/genes12101481","article-title":"Trends in the application of \u201comics\u201d to ecotoxicology and stress ecology","volume":"12","author":"Ebner","year":"2021","journal-title":"Genes"},{"key":"10.1016\/j.ecoenv.2024.117635_bib18","doi-asserted-by":"crossref","first-page":"4201","DOI":"10.1021\/es015848h","article-title":"Modes of action in ecotoxicology: their role in body burdens, species sensitivity, QSARs, and mixture effects","volume":"36","author":"Escher","year":"2002","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib19","doi-asserted-by":"crossref","DOI":"10.3389\/fmars.2021.679687","article-title":"The regulatory mechanism of sexual development in decapod crustaceans","volume":"8","author":"Farhadi","year":"2021","journal-title":"Front. Mar. Sci."},{"key":"10.1016\/j.ecoenv.2024.117635_bib20","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1897\/05-257R.1","article-title":"The use and misuse of biomarkers in ecotoxicology","volume":"25","author":"Forbes","year":"2009","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.ecoenv.2024.117635_bib21","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.886351","article-title":"Comparative metabolomics and lipidomics of four juvenoids application to Scylla paramamosain hepatopancreas: implications of lipid metabolism during ovarian maturation","volume":"13","author":"Fu","year":"2022","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib22","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s00360-011-0624-9","article-title":"The physiology of hyper-salinity tolerance in teleost fish: a review","volume":"182","author":"Gonzalez","year":"2011","journal-title":"J. Comp. Physiol. B"},{"key":"10.1016\/j.ecoenv.2024.117635_bib23","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1002\/etc.3676","article-title":"Toxicological perspective on the osmoregulation and ionoregulation physiology of major ions by freshwater animals: teleost fish, crustacea, aquatic insects, and Mollusca","volume":"36","author":"Griffith","year":"2016","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.ecoenv.2024.117635_bib24","first-page":"22","article-title":"Preliminary study on the effect of salinity on precocious maturation of Chinese mitten-handed crab Eriocheir sinensis","volume":"24","author":"Gu","year":"2002","journal-title":"Mar. Fish."},{"key":"10.1016\/j.ecoenv.2024.117635_bib25","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/s44339-024-00004-8","article-title":"Acute toxicity of sodium chloride-based road salt formulations to juvenile aquatic invertebrates","volume":"1","author":"Harwood","year":"2024","journal-title":"Discov. Toxicol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib26","first-page":"10","article-title":"Study on the growth characteristics of ecological aquaculture population of Chinese mitten crab in ponds","volume":"25","author":"He","year":"2005","journal-title":"Reserv. Fish."},{"key":"10.1016\/j.ecoenv.2024.117635_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2021.338298","article-title":"Metabolomics in chemical risk analysis - a review","volume":"1154","author":"Hernandez-Mesa","year":"2021","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.ecoenv.2024.117635_bib28","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1007\/s10695-023-01244-y","article-title":"Free amino acids in response to salinity changes in fishes: relationships to osmoregulation","volume":"49","author":"Huang","year":"2023","journal-title":"Fish. Physiol. Biochem."},{"key":"10.1016\/j.ecoenv.2024.117635_bib29","doi-asserted-by":"crossref","first-page":"4970","DOI":"10.1111\/are.15983","article-title":"Effects of salinity on reproductive characteristics and embryo quality of Eriocheir sinensis","volume":"53","author":"Huang","year":"2022","journal-title":"Aquac. Res."},{"key":"10.1016\/j.ecoenv.2024.117635_bib30","unstructured":"Jager, T., 2016. DEBkiss. A simple framework for animal energy budgets (Version 3.1). Leanpub."},{"key":"10.1016\/j.ecoenv.2024.117635_bib31","unstructured":"Jager, T., 2017. Making sense of chemical stress (Version 2). Leanpub."},{"key":"10.1016\/j.ecoenv.2024.117635_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecolmodel.2019.108904","article-title":"Revisiting simplified DEBtox models for analysing ecotoxicity data","volume":"416","author":"Jager","year":"2020","journal-title":"Ecol. Model."},{"key":"10.1016\/j.ecoenv.2024.117635_bib33","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1002\/ieam.2026","article-title":"How to evaluate the quality of toxicokinetic-toxicodynamic models in the context of environmental risk assessment","volume":"14","author":"Jager","year":"2018","journal-title":"Integr. Environ. Assess. Manag."},{"key":"10.1016\/j.ecoenv.2024.117635_bib34","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3354\/meps11098","article-title":"Parameterising a generic model for the dynamic energy budget of Antarctic krill Euphausia superba","volume":"519","author":"Jager","year":"2015","journal-title":"Mar. Ecol. Prog. Ser."},{"key":"10.1016\/j.ecoenv.2024.117635_bib35","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ecolmodel.2011.11.012","article-title":"Simplified Dynamic Energy Budget model for analysing ecotoxicity data","volume":"225","author":"Jager","year":"2012","journal-title":"Ecol. Model."},{"key":"10.1016\/j.ecoenv.2024.117635_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecolmodel.2022.110187","article-title":"Using the standard DEB animal model for toxicokinetic-toxicodynamic analysis","volume":"475","author":"Jager","year":"2023","journal-title":"Ecol. Model."},{"key":"10.1016\/j.ecoenv.2024.117635_bib37","series-title":"Dynamic Energy Budget Theory for Metabolic Organisation","author":"Kooijman","year":"2010"},{"key":"10.1016\/j.ecoenv.2024.117635_bib38","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1152\/physiolgenomics.00191.2013","article-title":"Transcriptome sequencing revealed the genes and pathways involved in salinity stress of Chinese mitten crab, Eriocheir sinensis","volume":"46","author":"Li","year":"2014","journal-title":"Physiol. Genom."},{"key":"10.1016\/j.ecoenv.2024.117635_bib39","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.cbpb.2005.12.019","article-title":"The site of vitellogenin synthesis in Chinese mitten-handed crab Eriocheir sinensis","volume":"143","author":"Li","year":"2006","journal-title":"Comp. Biochem. Physiol. Part B\u00a0Biochem. Mol. Biol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib40","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s10499-010-9400-1","article-title":"Advances in precocity research of the Chinese mitten crab Eriocheir sinensis","volume":"19","author":"Li","year":"2010","journal-title":"Aquac. Int."},{"key":"10.1016\/j.ecoenv.2024.117635_bib41","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s11802-008-0077-2","article-title":"Effect of salinity on hemolymph osmotic pressure, sodium concentration and Na+-K+-ATPase activity of gill of Chinese crab, Eriocheir sinensis","volume":"7","author":"Liu","year":"2008","journal-title":"J. Ocean Univ. China"},{"key":"10.1016\/j.ecoenv.2024.117635_bib42","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.ecoenv.2024.117635_bib43","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.3389\/fphys.2017.01072","article-title":"Physiological responses and ovarian development of female Chinese mitten crab Eriocheir sinensis subjected to different salinity conditions","volume":"8","author":"Long","year":"2017","journal-title":"Front. Physiol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib44","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/j.scitotenv.2016.06.170","article-title":"Developing and sustainably utilize the coastal mudflat areas in China","volume":"569-570","author":"Long","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2024.117635_bib45","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S1095-6433(03)00064-3","article-title":"Na++K+-ATPase in gills of aquatic crustacea","volume":"135","author":"Lucu","year":"2003","journal-title":"Comp. Biochem. Physiol. Part A\u00a0Mol. Integr. Physiol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib46","doi-asserted-by":"crossref","first-page":"21029","DOI":"10.1021\/acs.est.3c05079","article-title":"Toxicokinetic\u2013Toxicodynamic model to assess thermal stress","volume":"57","author":"Mangold-D\u00f6ring","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib47","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2021.673002","article-title":"Linking oxidative stress and DNA damage to changes in the expression of extracellular matrix components","volume":"12","author":"Martins","year":"2021","journal-title":"Front. Genet."},{"key":"10.1016\/j.ecoenv.2024.117635_bib48","series-title":"A Systems Biology Approach to Advancing Adverse Outcome Pathways for Risk Assessment","first-page":"177","article-title":"The application of omics data to the development of AOPs","author":"McBride","year":"2018"},{"key":"10.1016\/j.ecoenv.2024.117635_bib49","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1007\/s00360-012-0665-8","article-title":"Evolution of osmoregulatory patterns and gill ion transport mechanisms in the decapod crustacea: a review","volume":"182","author":"McNamara","year":"2012","journal-title":"J. Comp. Physiol. B"},{"key":"10.1016\/j.ecoenv.2024.117635_bib50","series-title":"Status of the world\u2019s soil resources: main report","author":"Montanarella","year":"2015"},{"key":"10.1016\/j.ecoenv.2024.117635_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.jenvman.2020.111736","article-title":"Soil salinity under climate change: challenges for sustainable agriculture and food security","volume":"280","author":"Mukhopadhyay","year":"2021","journal-title":"J. Environ. Manag."},{"key":"10.1016\/j.ecoenv.2024.117635_bib52","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1111\/j.1365-2656.2000.00448.x","article-title":"From molecules to ecosystems through dynamic energy budget models","volume":"69","author":"Nisbet","year":"2008","journal-title":"J. Anim. Ecol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib53","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.jembe.2012.01.001","article-title":"Effect of salinity on the physiology and bioenergetics of adult Chinese mitten crabs Eriocheir sinensis","volume":"416-417","author":"Normant","year":"2012","journal-title":"J. Exp. Mar. Biol. Ecol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib54","first-page":"91","article-title":"Study on morphological indicators and quality parameters of 1-year-old Chinese mitten crab in Datong Lake","volume":"40","author":"Peng","year":"2019","journal-title":"J. Hydroecol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib55","doi-asserted-by":"crossref","first-page":"R1269","DOI":"10.1152\/ajpregu.00516.2003","article-title":"The gill and homeostasis: transport under stress","volume":"285","author":"Pritchard","year":"2003","journal-title":"Am. J. Physiol. -Regul., Integr. Comp. Physiol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecolmodel.2020.109051","article-title":"A dynamic energy budget model for small yellow croaker Larimichthys polyactis: parameterisation and application in its main geographic distribution waters","volume":"427","author":"Ren","year":"2020","journal-title":"Ecol. Model."},{"key":"10.1016\/j.ecoenv.2024.117635_bib57","doi-asserted-by":"crossref","DOI":"10.1101\/pdb.prot5439","article-title":"Purification of RNA using TRIzol (TRI reagent)","volume":"2010","author":"Rio","year":"2010","journal-title":"Cold Spring Harb. Protoc."},{"key":"10.1016\/j.ecoenv.2024.117635_bib58","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1007\/s00216-010-3662-3","article-title":"Transcriptomics in ecotoxicology","volume":"397","author":"Schirmer","year":"2010","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.ecoenv.2024.117635_bib59","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/gcb.16438","article-title":"Three perspectives on the prediction of chemical effects in ecosystems","volume":"29","author":"Schneeweiss","year":"2022","journal-title":"Glob. Change Biol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib60","doi-asserted-by":"crossref","first-page":"7420","DOI":"10.1021\/acs.est.0c00140","article-title":"Modeling sublethal effects of chemicals: application of a simplified dynamic energy budget model to standard ecotoxicity data","volume":"54","author":"Sherborne","year":"2020","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib61","series-title":"Stress Indicators in Fish","first-page":"405","author":"Sopinka","year":"2016"},{"key":"10.1016\/j.ecoenv.2024.117635_bib62","doi-asserted-by":"crossref","first-page":"3413","DOI":"10.1098\/rstb.2010.0166","article-title":"Dynamic energy budget theory restores coherence in biology","volume":"365","author":"Sousa","year":"2010","journal-title":"Philos. Trans. R. Soc. B\u00a0Biol. Sci."},{"key":"10.1016\/j.ecoenv.2024.117635_bib63","series-title":"Stress Ecology: Environmental Stress as Ecological Driving Force and Key Player in Evolution","first-page":"161","article-title":"The potential of stress response: ecological transcriptomics","author":"Steinberg","year":"2012"},{"key":"10.1016\/j.ecoenv.2024.117635_bib64","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1002\/etc.5680","article-title":"Connecting suborganismal data to bioenergetic processes: killifish embryos exposed to a dioxin-like compound","volume":"42","author":"Stevenson","year":"2023","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.ecoenv.2024.117635_bib65","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12562-010-0301-z","article-title":"Mechanisms and control of vitellogenesis in crustaceans","volume":"77","author":"Subramoniam","year":"2010","journal-title":"Fish. Sci."},{"key":"10.1016\/j.ecoenv.2024.117635_bib66","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1093\/icesjms\/fsy164","article-title":"Adapting the dynamic energy budget (DEB) approach to include non-continuous growth (moulting) and provide better predictions of biological performance in crustaceans","volume":"76","author":"Talbot","year":"2019","journal-title":"ICES J. Mar. Sci."},{"key":"10.1016\/j.ecoenv.2024.117635_bib67","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1111\/are.15616","article-title":"Toxicity, physiological, histopathological, handling, growth and antiparasitic effects of the sodium chloride (salt) in the freshwater fish aquaculture","volume":"53","author":"Tavares-Dias","year":"2021","journal-title":"Aquac. Res."},{"key":"10.1016\/j.ecoenv.2024.117635_bib68","doi-asserted-by":"crossref","first-page":"2240","DOI":"10.1002\/etc.5409","article-title":"Predicting combined effects of chemical stressors: population-level effects of organic chemical mixtures with a dynamic energy budget individual-based model","volume":"41","author":"Vlaeminck","year":"2022","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.ecoenv.2024.117635_bib69","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.gene.2018.07.059","article-title":"A proteomics of gills approach to understanding salinity adaptation of Scylla paramamosain","volume":"677","author":"Wang","year":"2018","journal-title":"Gene"},{"key":"10.1016\/j.ecoenv.2024.117635_bib70","doi-asserted-by":"crossref","first-page":"11171","DOI":"10.3390\/ijms241311171","article-title":"Integrated analysis of transcriptomics and metabolomics unveil the novel insight of one-year-old precocious mechanism in the Chinese mitten crab, Eriocheir sinensis","volume":"24","author":"Wang","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ecoenv.2024.117635_bib71","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2024.119956","article-title":"Characterization of the molecular, cellular, and behavioral changes caused by exposure to a saline-alkali environment in the Chinese mitten crab, Eriocheir sinensis","volume":"262","author":"Wang","year":"2024","journal-title":"Environ. Res."},{"key":"10.1016\/j.ecoenv.2024.117635_bib72","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2022.737989","article-title":"Effects of acute salinity stress on osmoregulation, antioxidant capacity and physiological metabolism of female Chinese mitten crabs (Eriocheir sinensis)","volume":"552","author":"Wang","year":"2022","journal-title":"Aquaculture"},{"key":"10.1016\/j.ecoenv.2024.117635_bib73","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s10709-018-0021-3","article-title":"Adaptive evolution of osmoregulatory-related genes provides insight into salinity adaptation in Chinese mitten crab, Eriocheir sinensis","volume":"146","author":"Wang","year":"2018","journal-title":"Genetica"},{"key":"10.1016\/j.ecoenv.2024.117635_bib74","doi-asserted-by":"crossref","first-page":"5462","DOI":"10.1111\/are.15416","article-title":"Changes in calcium content, histopathology and calreticulin expression in the juvenile Chinese mitten crab Eriocheir sinensis under different salinity conditions","volume":"52","author":"Yang","year":"2021","journal-title":"Aquac. Res."},{"key":"10.1016\/j.ecoenv.2024.117635_bib75","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2021.737776","article-title":"Effects of salinity stress on osmotic pressure, free amino acids, and immune-associated parameters of the juvenile Chinese mitten crab, Eriocheir sinensis","volume":"549","author":"Yang","year":"2022","journal-title":"Aquaculture"},{"key":"10.1016\/j.ecoenv.2024.117635_bib76","series-title":"Aquaculture Technology of Eriocheir sinensis","author":"Zhang","year":"2002"},{"key":"10.1016\/j.ecoenv.2024.117635_bib77","doi-asserted-by":"crossref","first-page":"3842","DOI":"10.1021\/acs.est.7b06494","article-title":"Omics advances in ecotoxicology","volume":"52","author":"Zhang","year":"2018","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ecoenv.2024.117635_bib78","doi-asserted-by":"crossref","first-page":"4173","DOI":"10.1111\/are.14759","article-title":"Effects of salinity on the ions important and sodium-potassium ATPase in osmoregulation, cortisol, amino acids, digestive and immune enzymes in Scylla paramamosain during indoor overwintering","volume":"51","author":"Zhou","year":"2020","journal-title":"Aquac. Res."},{"key":"10.1016\/j.ecoenv.2024.117635_bib79","first-page":"4328","article-title":"Understanding the generalization benefit of model invariance from a data perspective","volume":"34","author":"Zhu","year":"2021","journal-title":"Adv. Neural Inf. Process. Syst."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651324017111?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651324017111?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T08:54:42Z","timestamp":1762246482000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651324017111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":79,"alternative-id":["S0147651324017111"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2024.117635","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Application of the DEB-TKTD model with multi-omics data: Prediction of life history traits of Chinese mitten crab (Eriocheir sinensis) under different salinities","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2024.117635","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"117635"}}