{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T21:20:56Z","timestamp":1793049656082,"version":"4.5.0"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T00:00:00Z","timestamp":1736553600000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100022600","name":"Taipei Municipal Wan-Fang Hospital","doi-asserted-by":"publisher","award":["112TMU-WFH-04"],"award-info":[{"award-number":["112TMU-WFH-04"]}],"id":[{"id":"10.13039\/501100022600","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004700","name":"Taipei Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST 108-2314-B-038-089"],"award-info":[{"award-number":["MOST 108-2314-B-038-089"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["111-2314-B-002-240-MY3"],"award-info":[{"award-number":["111-2314-B-002-240-MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["107-2314-B-038-073"],"award-info":[{"award-number":["107-2314-B-038-073"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST 111-2314-B-038-052"],"award-info":[{"award-number":["MOST 111-2314-B-038-052"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["NSTC 112-2314-B-038-094"],"award-info":[{"award-number":["NSTC 112-2314-B-038-094"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST 109-2314-B-038-081"],"award-info":[{"award-number":["MOST 109-2314-B-038-081"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST 110-2314-B-038-054"],"award-info":[{"award-number":["MOST 110-2314-B-038-054"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST 109-2314-B-038-067"],"award-info":[{"award-number":["MOST 109-2314-B-038-067"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["108-2314-B-038 -089"],"award-info":[{"award-number":["108-2314-B-038 -089"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.ecoenv.2025.117726","type":"journal-article","created":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T17:59:31Z","timestamp":1737136771000},"page":"117726","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Plasma myeloperoxidase interactions with cadmium, lead, arsenic, and selenium and their impact on chronic kidney disease"],"prefix":"10.1016","volume":"290","author":[{"given":"Hsi-Hsien","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-Li","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Yin","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-Chieh","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Horng-Sheng","family":"Shiue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng-Lun","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Chin","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Mei","family":"Hsueh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2025.117726_bib1","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1289\/ehp.1307110","article-title":"Non-renal effects and the risk assessment of environmental cadmium exposure","volume":"122","author":"Akesson","year":"2014","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ecoenv.2025.117726_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2023.110833","article-title":"The melatonin receptor agonist agomelatine protects against acute pancreatitis induced by cadmium by attenuating inflammation and oxidative stress and modulating Nrf2\/HO-1 pathway","volume":"124","author":"Alruhaimi","year":"2023","journal-title":"Int Immunopharmacol."},{"key":"10.1016\/j.ecoenv.2025.117726_bib3","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.abb.2018.01.004","article-title":"Myeloperoxidase: Its role for host defense, inflammation, and neutrophil function","volume":"640","author":"Aratani","year":"2018","journal-title":"Arch. Biochem Biophys."},{"key":"10.1016\/j.ecoenv.2025.117726_bib4","doi-asserted-by":"crossref","DOI":"10.3945\/ajcn.2009.27230F","article-title":"Methods of assessment of selenium status in humans: a systematic review","volume":"89","author":"Ashton","year":"2009","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.ecoenv.2025.117726_bib5","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.taap.2010.08.013","article-title":"Evaluation of the serum catalase and myeloperoxidase activities in chronic arsenic-exposed individuals and concomitant cytogenetic damage","volume":"249","author":"Banerjee","year":"2010","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.ecoenv.2025.117726_bib6","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1289\/ehp.7917","article-title":"A critical review of biomarkers used for monitoring human exposure to lead: advantages, limitations, and future needs","volume":"113","author":"Barbosa","year":"2005","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ecoenv.2025.117726_bib7","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1289\/ehp.7337","article-title":"Urinary creatinine concentrations in the U.S. population: implications for urinary biologic monitoring measurements","volume":"113","author":"Barr","year":"2005","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ecoenv.2025.117726_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtemb.2024.127410","article-title":"Dosage-effect of selenium supplementation on blood glucose and oxidative stress in type 2 diabetes mellitus and normal mice","volume":"83","author":"Cai","year":"2024","journal-title":"J. Trace Elem. Med Biol."},{"key":"10.1016\/j.ecoenv.2025.117726_bib9","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1182\/blood.V53.4.588.588","article-title":"Induction of myeloperoxidase deficiency in granulocytes in lead-intoxicated dogs","volume":"53","author":"Caldwell","year":"1979","journal-title":"Blood"},{"key":"10.1016\/j.ecoenv.2025.117726_bib10","doi-asserted-by":"crossref","first-page":"367","DOI":"10.4236\/ajac.2019.109025","article-title":"Single laboratory validation of determination of 13 trace elements in rice by ICP-MS with an overview of challenges encountered","volume":"10","author":"Chandrasiri","year":"2019","journal-title":"Am. J. Anal. Chem."},{"key":"10.1016\/j.ecoenv.2025.117726_bib11","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.taap.2014.05.011","article-title":"Renin-angiotensin-aldosterone system related gene polymorphisms and urinary total arsenic is related to chronic kidney disease","volume":"279","author":"Chen","year":"2014","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.ecoenv.2025.117726_bib12","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25052511","article-title":"Selenium lessens osteoarthritis by protecting articular chondrocytes from oxidative damage through Nrf2 and NF-kappaB pathways","volume":"25","author":"Cheng","year":"2024","journal-title":"Int J. Mol. Sci."},{"key":"10.1016\/j.ecoenv.2025.117726_bib13","doi-asserted-by":"crossref","DOI":"10.3390\/jcm11237167","article-title":"Eryptosis in patients with chronic kidney disease: a possible relationship with oxidative stress and inflammatory markers","volume":"11","author":"Clementi","year":"2022","journal-title":"J. Clin. Med"},{"key":"10.1016\/j.ecoenv.2025.117726_bib14","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1053\/j.ajkd.2019.09.006","article-title":"Myeloperoxidase and the risk of CKD progression, cardiovascular disease, and death in the chronic renal insufficiency cohort (CRIC) Study","volume":"76","author":"Correa","year":"2020","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.ecoenv.2025.117726_bib15","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1089\/ars.2020.8030","article-title":"The role of myeloperoxidase in biomolecule modification, chronic inflammation, and disease","volume":"32","author":"Davies","year":"2020","journal-title":"Antioxid. Redox Signal"},{"key":"10.1016\/j.ecoenv.2025.117726_bib16","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/S0272-6386(99)70375-6","article-title":"Neutrophils and renal failure","volume":"34","author":"Heinzelmann","year":"1999","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.ecoenv.2025.117726_bib17","first-page":"589","article-title":"Serum beta-carotene level, arsenic methylation capability, and incidence of skin cancer","volume":"6","author":"Hsueh","year":"1997","journal-title":"Cancer Epidemiol., Biomark. Prev."},{"key":"10.1016\/j.ecoenv.2025.117726_bib18","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1053\/j.ajkd.2009.06.016","article-title":"Urinary arsenic species and CKD in a Taiwanese population: a case-control study","volume":"54","author":"Hsueh","year":"2009","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.ecoenv.2025.117726_bib19","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1289\/ehp.9058","article-title":"Biomarkers of exposure: a case study with inorganic arsenic","volume":"114","author":"Hughes","year":"2006","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ecoenv.2025.117726_bib20","first-page":"87","article-title":"Response of antioxidant enzymes and redox metabolites to cadmium-induced oxidative stress in CRL-1439 normal rat liver cells","volume":"14","author":"Ikediobi","year":"2004","journal-title":"Int J. Mol. Med"},{"key":"10.1016\/j.ecoenv.2025.117726_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110047","article-title":"Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-kappaB and Nrf2 pathways","volume":"126","author":"Jin","year":"2020","journal-title":"Biomed. Pharm."},{"key":"10.1016\/j.ecoenv.2025.117726_bib22","doi-asserted-by":"crossref","unstructured":"Kdigo 2012 KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. https:\/\/doi.org\/10.1038\/kisup.2012.71.","DOI":"10.1038\/kisup.2012.71"},{"key":"10.1016\/j.ecoenv.2025.117726_bib23","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/1069743","article-title":"Role of myeloperoxidase in patients with chronic kidney disease","volume":"2016","author":"Kisic","year":"2016","journal-title":"Oxid. Med Cell Longev."},{"key":"10.1016\/j.ecoenv.2025.117726_bib24","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1182\/blood-2010-05-284513","article-title":"Myeloperoxidase attracts neutrophils by physical forces","volume":"117","author":"Klinke","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.ecoenv.2025.117726_bib25","first-page":"508","article-title":"Subchronic oral cadmium exposure exerts both stimulatory and suppressive effects on pulmonary inflammation\/immune reactivity in rats","volume":"32","author":"Kulas","year":"2019","journal-title":"Biomed. Environ. Sci."},{"issue":"1","key":"10.1016\/j.ecoenv.2025.117726_bib26","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1016\/j.jfma.2021.12.013","article-title":"Trends in the incidence and prevalence of end-stage kidney disease requiring dialysis in Taiwan: 2010-2018","volume":"121","author":"Lai","year":"2022","journal-title":"J. Formos. Med. Assoc."},{"key":"10.1016\/j.ecoenv.2025.117726_bib27","doi-asserted-by":"crossref","first-page":"F407","DOI":"10.1152\/ajprenal.00262.2014","article-title":"Myeloperoxidase deficiency ameliorates progression of chronic kidney disease in mice","volume":"307","author":"Lehners","year":"2014","journal-title":"Am. J. Physiol. Ren. Physiol."},{"key":"10.1016\/j.ecoenv.2025.117726_bib28","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/sj.ki.5002343","article-title":"Chronic kidney disease as a global public health problem: approaches and initiatives - a position statement from Kidney Disease Improving Global Outcomes","volume":"72","author":"Levey","year":"2007","journal-title":"Kidney Int"},{"key":"10.1016\/j.ecoenv.2025.117726_bib29","doi-asserted-by":"crossref","first-page":"461","DOI":"10.7326\/0003-4819-130-6-199903160-00002","article-title":"A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group","volume":"130","author":"Levey","year":"1999","journal-title":"Ann. Intern. Med"},{"key":"10.1016\/j.ecoenv.2025.117726_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.114846","article-title":"Non-essential and essential trace element mixtures and kidney function in early pregnancy - a cross-sectional analysis in project viva","volume":"216","author":"Lin","year":"2023","journal-title":"Environ. Res"},{"key":"10.1016\/j.ecoenv.2025.117726_bib31","doi-asserted-by":"crossref","DOI":"10.3390\/antiox13010132","article-title":"The roles of neutrophil-derived myeloperoxidase (MPO) in diseases: the new progress","volume":"13","author":"Lin","year":"2024","journal-title":"Antioxidants"},{"key":"10.1016\/j.ecoenv.2025.117726_bib32","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1177\/1479164118755044","article-title":"Evaluation of the oxidative stress-related genes ALOX5, ALOX5AP, GPX1, GPX3 and MPO for contribution to the risk of type 2 diabetes mellitus in the Han Chinese population","volume":"15","author":"Liu","year":"2018","journal-title":"Diab Vasc. Dis. Res."},{"key":"10.1016\/j.ecoenv.2025.117726_bib33","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1159\/000482023","article-title":"Genetic variations of oxidative stress related genes ALOX5, ALOX5AP and MPO modulate ischemic stroke susceptibility through main effects and epistatic interactions in a chinese population","volume":"43","author":"Liu","year":"2017","journal-title":"Cell Physiol. Biochem"},{"key":"10.1016\/j.ecoenv.2025.117726_bib34","doi-asserted-by":"crossref","first-page":"177","DOI":"10.21037\/atm.2019.03.66","article-title":"Effects of sub-chronic, low-dose cadmium exposure on kidney damage and potential mechanisms","volume":"7","author":"Liu","year":"2019","journal-title":"Ann. Transl. Med"},{"key":"10.1016\/j.ecoenv.2025.117726_bib35","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgh-2021-007525","article-title":"Prevalence of chronic kidney disease in Asia: a systematic review and analysis","volume":"7","author":"Liyanage","year":"2022","journal-title":"BMJ Glob. Health"},{"key":"10.1016\/j.ecoenv.2025.117726_bib36","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1046\/j.1523-1755.2003.00336.x","article-title":"Myeloperoxidase in kidney disease","volume":"64","author":"Malle","year":"2003","journal-title":"Kidney Int."},{"key":"10.1016\/j.ecoenv.2025.117726_bib37","doi-asserted-by":"crossref","DOI":"10.3390\/ijms231911105","article-title":"Molecular mechanisms of cellular injury and role of toxic heavy metals in chronic kidney disease","volume":"23","author":"Mishra","year":"2022","journal-title":"Int J. Mol. Sci."},{"key":"10.1016\/j.ecoenv.2025.117726_bib38","doi-asserted-by":"crossref","first-page":"15208","DOI":"10.1016\/S0021-9258(18)48159-8","article-title":"Chromosomal gene structure of human myeloperoxidase and regulation of its expression by granulocyte colony-stimulating factor","volume":"262","author":"Morishita","year":"1987","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ecoenv.2025.117726_bib39","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1038\/ki.2012.235","article-title":"Polymorphisms in the myeloperoxidase gene locus are associated with acute kidney injury-related outcomes","volume":"82","author":"Perianayagam","year":"2012","journal-title":"Kidney Int."},{"key":"10.1016\/j.ecoenv.2025.117726_bib40","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s00005-011-0156-8","article-title":"Neutrophil myeloperoxidase: soldier and statesman","volume":"60","author":"Prokopowicz","year":"2012","journal-title":"Arch. Immunol. Ther. Exp. (Warsz. )"},{"key":"10.1016\/j.ecoenv.2025.117726_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.122686","article-title":"Toxic ties: unraveling the complex relationship between endocrine disrupting chemicals and chronic kidney disease","volume":"338","author":"Ramya Ranjan Nayak","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2025.117726_bib42","doi-asserted-by":"crossref","DOI":"10.3390\/cells13010083","article-title":"Is environmental cadmium exposure causally related to diabetes and obesity?","volume":"13","author":"Satarug","year":"2023","journal-title":"Cells"},{"key":"10.1016\/j.ecoenv.2025.117726_bib43","doi-asserted-by":"crossref","DOI":"10.3390\/toxics8040086","article-title":"Cadmium and lead exposure, nephrotoxicity, and mortality","volume":"8","author":"Satarug","year":"2020","journal-title":"Toxics"},{"key":"10.1016\/j.ecoenv.2025.117726_bib44","first-page":"107","article-title":"Kinetic investigation of myeloperoxidase upon interaction with copper, cadmium, and lead ions","volume":"15","author":"Shabani","year":"2011","journal-title":"Iran. Biomed. J."},{"key":"10.1016\/j.ecoenv.2025.117726_bib45","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.ijcard.2010.08.008","article-title":"Oxidative stress biomarkers as predictors of cardiovascular disease","volume":"147","author":"Strobel","year":"2011","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ecoenv.2025.117726_bib46","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.ctrv.2009.12.008","article-title":"Ingestion of selenium and other antioxidants during prostate cancer radiotherapy: a good thing?","volume":"36","author":"Tabassum","year":"2010","journal-title":"Cancer Treat. Rev."},{"key":"10.1016\/j.ecoenv.2025.117726_bib47","doi-asserted-by":"crossref","DOI":"10.3390\/diagnostics11020282","article-title":"Associations among heavy metals and proteinuria and chronic kidney disease","volume":"11","author":"Tsai","year":"2021","journal-title":"Diagnostics"},{"key":"10.1016\/j.ecoenv.2025.117726_bib48","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1111\/nep.12187","article-title":"Myeloperoxidase in chronic kidney disease: role of visceral fat","volume":"19","author":"Tsai","year":"2014","journal-title":"Nephrol. (Carlton)"},{"key":"10.1016\/j.ecoenv.2025.117726_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.amjcard.2008.02.006","article-title":"In vivo markers of oxidative stress and therapeutic interventions","volume":"101","author":"Tsimikas","year":"2008","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.ecoenv.2025.117726_bib50","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1097\/EDE.0000000000000121","article-title":"A unification of mediation and interaction: a 4-way decomposition","volume":"25","author":"VanderWeele","year":"2014","journal-title":"Epidemiology"},{"key":"10.1016\/j.ecoenv.2025.117726_bib51","doi-asserted-by":"crossref","first-page":"10263","DOI":"10.1111\/jcmm.15644","article-title":"SNP rs2243828 in MPO associated with myeloperoxidase level and atrial fibrillation risk in Chinese Han population","volume":"24","author":"Wang","year":"2020","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.ecoenv.2025.117726_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.114219","article-title":"Air pollutants, genetic factors, and risk of chronic kidney disease: findings from the UK Biobank","volume":"247","author":"Wang","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2025.117726_bib53","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s00204-009-0425-z","article-title":"Oxidative stress and apoptotic changes in primary cultures of rat proximal tubular cells exposed to lead","volume":"83","author":"Wang","year":"2009","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.ecoenv.2025.117726_bib54","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.jhazmat.2019.04.082","article-title":"The association between plasma selenium and chronic kidney disease related to lead, cadmium and arsenic exposure in a Taiwanese population","volume":"375","author":"Wu","year":"2019","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2025.117726_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2024.123890","article-title":"Enhancing soil health to minimize cadmium accumulation in agro-products: the role of microorganisms, organic matter, and nutrients","volume":"348","author":"Xin","year":"2024","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2025.117726_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.163100","article-title":"Association of urinary exposure to multiple metal(loid)s with kidney function from a national cross-sectional study","volume":"882","author":"Yu","year":"2023","journal-title":"Sci. Total Environ."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651325000624?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651325000624?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T08:58:18Z","timestamp":1762246698000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651325000624"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":56,"alternative-id":["S0147651325000624"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2025.117726","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Plasma myeloperoxidase interactions with cadmium, lead, arsenic, and selenium and their impact on chronic kidney disease","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2025.117726","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"117726"}}