{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:57:42Z","timestamp":1782435462260,"version":"3.54.5"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T00:00:00Z","timestamp":1736726400000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82204085"],"award-info":[{"award-number":["82204085"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82173554"],"award-info":[{"award-number":["82173554"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.ecoenv.2025.117736","type":"journal-article","created":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T15:18:46Z","timestamp":1736954326000},"page":"117736","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Exposure to nano-polystyrene during pregnancy leads to Alzheimer's disease-related pathological changes in adult offspring"],"prefix":"10.1016","volume":"290","author":[{"given":"Fengxu","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonghua","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengnan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengna","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoping","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoke","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shali","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiyun","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyuan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2025.117736_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2019.109089","article-title":"A critical viewpoint on current issues, limitations, and future research needs on micro- and nanoplastic studies: from the detection to the toxicological assessment","volume":"182","author":"Barbosa","year":"2020","journal-title":"Environ. Res."},{"issue":"6496","key":"10.1016\/j.ecoenv.2025.117736_bib2","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1126\/science.aaz5819","article-title":"Plastic rain in protected areas of the United States","volume":"368","author":"Brahney","year":"2020","journal-title":"Science"},{"issue":"7","key":"10.1016\/j.ecoenv.2025.117736_bib3","doi-asserted-by":"crossref","DOI":"10.3390\/pharmaceutics13070921","article-title":"Detection of microplastic in human placenta and meconium in a clinical setting","volume":"13","author":"Braun","year":"2021","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.ecoenv.2025.117736_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.158666","article-title":"Maternal exposure to polystyrene nanoparticles retarded fetal growth and triggered metabolic disorders of placenta and fetus in mice","volume":"854","author":"Chen","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2025.117736_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2024.116233","article-title":"Dual-specificity tyrosine phosphorylation-regulated kinase 1A promotes the inclusion of amyloid precursor protein exon 7","volume":"224","author":"Chu","year":"2024","journal-title":"Biochem Pharm."},{"key":"10.1016\/j.ecoenv.2025.117736_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2021.112609","article-title":"Toxicity, uptake, and nuclear translocation of ingested micro-nanoplastics in an in vitro model of the small intestinal epithelium","volume":"158","author":"Deloid","year":"2021","journal-title":"Food Chem. Toxicol."},{"issue":"7","key":"10.1016\/j.ecoenv.2025.117736_bib7","doi-asserted-by":"crossref","first-page":"3824","DOI":"10.1007\/s12035-023-03318-7","article-title":"miR-671-5p upregulation attenuates blood-brain barrier disruption in the ischemia stroke model via the NF-\u043aB\/MMP-9 signaling pathway","volume":"60","author":"Deng","year":"2023","journal-title":"Mol. Neurobiol."},{"issue":"2","key":"10.1016\/j.ecoenv.2025.117736_bib8","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1002\/jmri.26810","article-title":"Increased cerebral blood flow with increased amyloid burden in the preclinical phase of Alzheimer's disease","volume":"51","author":"Fazlollahi","year":"2020","journal-title":"J. Magn. Reson Imaging"},{"issue":"1","key":"10.1016\/j.ecoenv.2025.117736_bib9","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/s12989-020-00385-9","article-title":"Nanopolystyrene translocation and fetal deposition after acute lung exposure during late-stage pregnancy","volume":"17","author":"Fournier","year":"2020","journal-title":"Part Fibre Toxicol."},{"key":"10.1016\/j.ecoenv.2025.117736_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2024.123714","article-title":"Quantifying potential marine debris sources and potential threats to penguins on the West Antarctic Peninsula","volume":"347","author":"Gallagher","year":"2024","journal-title":"Environ. Pollut."},{"issue":"6","key":"10.1016\/j.ecoenv.2025.117736_bib11","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2011.50","article-title":"Astrocytes are important mediators of A\u03b2-induced neurotoxicity and tau phosphorylation in primary culture","volume":"2","author":"Garwood","year":"2011","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.ecoenv.2025.117736_bib12","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.716177","article-title":"Anti-inflammatory activity of a polypeptide fraction from achyranthes bidentate in amyloid \u03b2 oligomers induced model of Alzheimer's disease","volume":"12","author":"Ge","year":"2021","journal-title":"Front Pharm."},{"issue":"7","key":"10.1016\/j.ecoenv.2025.117736_bib13","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.1700782","article-title":"Production, use, and fate of all plastics ever made","volume":"3","author":"Geyer","year":"2017","journal-title":"Sci. Adv."},{"key":"10.1016\/j.ecoenv.2025.117736_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.133032","article-title":"Molecular mechanisms of nano-sized polystyrene plastics induced cytotoxicity and immunotoxicity in Eisenia fetida","volume":"465","author":"He","year":"2024","journal-title":"J. Hazard Mater."},{"issue":"10","key":"10.1016\/j.ecoenv.2025.117736_bib15","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1038\/s41583-018-0055-7","article-title":"Inflammasome signalling in brain function and neurodegenerative disease","volume":"19","author":"Heneka","year":"2018","journal-title":"Nat. Rev. Neurosci."},{"issue":"7784","key":"10.1016\/j.ecoenv.2025.117736_bib16","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/s41586-019-1769-z","article-title":"NLRP3 inflammasome activation drives tau pathology","volume":"575","author":"Ising","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.ecoenv.2025.117736_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.127815","article-title":"Maternal exposure to polystyrene nanoplastics causes brain abnormalities in progeny","volume":"426","author":"Jeong","year":"2022","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.ecoenv.2025.117736_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.162101","article-title":"Dysregulation of the microbiota-brain axis during long-term exposure to polystyrene nanoplastics in rats and the protective role of dihydrocaffeic acid","volume":"874","author":"Jiang","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2025.117736_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107131","article-title":"Polystyrene micro-\/nanoplastics induced hematopoietic damages via the crosstalk of gut microbiota, metabolites, and cytokines","volume":"161","author":"Jing","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.ecoenv.2025.117736_bib20","article-title":"Embryonic exposure of polystyrene nanoplastics affects cardiac development","volume":"906","author":"Li","year":"2024","journal-title":"Sci. Total Environ."},{"issue":"12","key":"10.1016\/j.ecoenv.2025.117736_bib21","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1111\/cns.13970","article-title":"Tau antibody 77G7 targeting microtubule binding domain suppresses proteopathic tau to seed tau aggregation","volume":"28","author":"Li","year":"2022","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.ecoenv.2025.117736_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.115749","article-title":"Chronic exposure to polystyrene nanoplastics induces intestinal mechanical and immune barrier dysfunction in mice","volume":"269","author":"Li","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"10","key":"10.1016\/j.ecoenv.2025.117736_bib23","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1002\/ar.25203","article-title":"Ferulic acid improves cognitive impairment by regulating jumonji C domain-containing protein 6 and synaptophysin in the hippocampus in neonatal and juvenile rats with intrauterine hypoxia during pregnancy","volume":"306","author":"Li","year":"2023","journal-title":"Anat. Rec. (Hoboken)"},{"key":"10.1016\/j.ecoenv.2025.117736_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2022.153338","article-title":"Polystyrene nanoplastics exacerbate lipopolysaccharide-induced myocardial fibrosis and autophagy in mice via ROS\/TGF-\u03b21\/Smad","volume":"480","author":"Lin","year":"2022","journal-title":"Toxicology"},{"issue":"1","key":"10.1016\/j.ecoenv.2025.117736_bib25","article-title":"Protective mechanism of Erigeron breviscapus injection on blood-brain barrier injury induced by cerebral ischemia in rats","volume":"11","author":"Liu","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ecoenv.2025.117736_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2023.114378","article-title":"TRPML1 contributes to antimony-induced nephrotoxicity by initiating ferroptosis via chaperone-mediated autophagy","volume":"184","author":"Liu","year":"2024","journal-title":"Food Chem. Toxicol."},{"issue":"4","key":"10.1016\/j.ecoenv.2025.117736_bib27","doi-asserted-by":"crossref","DOI":"10.3390\/molecules27041210","article-title":"Amyloidosis in Alzheimer's disease: pathogeny, etiology, and related therapeutic directions","volume":"27","author":"Ma","year":"2022","journal-title":"Molecules"},{"issue":"9","key":"10.1016\/j.ecoenv.2025.117736_bib28","doi-asserted-by":"crossref","first-page":"10315","DOI":"10.1096\/fj.201900423R","article-title":"Altered SPMs and age-associated decrease in brain DHA in APOE4 female mice","volume":"33","author":"Martinsen","year":"2019","journal-title":"Faseb J."},{"key":"10.1016\/j.ecoenv.2025.117736_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2021.105387","article-title":"Polystyrene nano\/microplastics induce microbiota dysbiosis, oxidative damage, and innate immune disruption in zebrafish","volume":"163","author":"Pei","year":"2022","journal-title":"Microb Pathog."},{"issue":"1","key":"10.1016\/j.ecoenv.2025.117736_bib30","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/s13024-022-00545-9","article-title":"CX3CR1 deficiency aggravates amyloid driven neuronal pathology and cognitive decline in Alzheimer's disease","volume":"17","author":"Puntambekar","year":"2022","journal-title":"Mol. Neurodegener."},{"issue":"6","key":"10.1016\/j.ecoenv.2025.117736_bib31","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.2174\/1570159X21666230407124146","article-title":"A comprehensive review on the importance of MiRNA-206 in the animal model and human diseases","volume":"22","author":"Qi","year":"2024","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.ecoenv.2025.117736_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.134466","article-title":"The involvement of SigmaR1(K142) degradation mediated by ERAD in neural senescence linked with CdCl(2) exposure","volume":"472","author":"Qian","year":"2024","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.ecoenv.2025.117736_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.143872","article-title":"Potential human health risks due to environmental exposure to nano- and microplastics and knowledge gaps: A scoping review","volume":"757","author":"Rahman","year":"2021","journal-title":"Sci. Total Environ."},{"issue":"1","key":"10.1016\/j.ecoenv.2025.117736_bib34","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1002\/tox.23970","article-title":"Arsenic and polystyrene-nano plastics co-exposure induced testicular toxicity: triggers oxidative stress and promotes apoptosis and inflammation in mice","volume":"39","author":"Rao","year":"2024","journal-title":"Environ. Toxicol."},{"issue":"11","key":"10.1016\/j.ecoenv.2025.117736_bib35","first-page":"1558","article-title":"Genetic factors and a polygenic model of Alzheimer's disease","volume":"35","author":"Rogvea","year":"1999","journal-title":"Genetika"},{"issue":"1","key":"10.1016\/j.ecoenv.2025.117736_bib36","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s12989-023-00561-7","article-title":"Comparison of PET tracing and biodistribution between (64)Cu-labeled micro-and nano-polystyrene in a murine inhalation model","volume":"21","author":"Shanmugiah","year":"2024","journal-title":"Part Fibre Toxicol."},{"issue":"3","key":"10.1016\/j.ecoenv.2025.117736_bib37","article-title":"Reproductive toxicity perspectives of nanoparticles: an update","volume":"13","author":"Sree","year":"2024","journal-title":"Toxicol. Res. (Camb.)"},{"issue":"11","key":"10.1016\/j.ecoenv.2025.117736_bib38","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1038\/s41401-024-01326-4","article-title":"A new tau dephosphorylation-targeting chimera for the treatment of tauopathies","volume":"45","author":"Su","year":"2024","journal-title":"Acta Pharm. Sin."},{"key":"10.1016\/j.ecoenv.2025.117736_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2023.113634","article-title":"Polystyrene nanoplastics inhibit StAR expression by activating HIF-1\u03b1 via ERK1\/2 MAPK and AKT pathways in TM3 Leydig cells and testicular tissues of mice","volume":"173","author":"Sui","year":"2023","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.ecoenv.2025.117736_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2024.141165","article-title":"Polystyrene microplastics induced disturbances in neuronal arborization and dendritic spine density in mice prefrontal cortex","volume":"351","author":"Suman","year":"2024","journal-title":"Chemosphere"},{"issue":"3","key":"10.1016\/j.ecoenv.2025.117736_bib41","doi-asserted-by":"crossref","first-page":"2440","DOI":"10.1021\/acsnano.2c09729","article-title":"Ferroptosis is involved in sex-specific small intestinal toxicity in the offspring of adult mice exposed to polystyrene nanoplastics during pregnancy","volume":"17","author":"Tang","year":"2023","journal-title":"ACS Nano"},{"issue":"11","key":"10.1016\/j.ecoenv.2025.117736_bib42","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph18115833","article-title":"Acute and sub-chronic effects of microplastics (3 and 10 \u00b5m) on the human intestinal cells HT-29","volume":"18","author":"Visalli","year":"2021","journal-title":"Int J. Environ. Res Public Health"},{"issue":"12","key":"10.1016\/j.ecoenv.2025.117736_bib43","doi-asserted-by":"crossref","first-page":"4474","DOI":"10.1093\/brain\/awac236","article-title":"Activation of Wnt\/\u03b2-catenin pathway mitigates blood-brain barrier dysfunction in Alzheimer's disease","volume":"145","author":"Wang","year":"2022","journal-title":"Brain"},{"issue":"22","key":"10.1016\/j.ecoenv.2025.117736_bib44","doi-asserted-by":"crossref","first-page":"4153","DOI":"10.1016\/j.cell.2022.09.033","article-title":"TREM2 drives microglia response to amyloid-\u03b2 via SYK-dependent and -independent pathways","volume":"185","author":"Wang","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.ecoenv.2025.117736_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.138255","article-title":"Effects of polystyrene nanoplastic gestational exposure on mice","volume":"324","author":"Wang","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2025.117736_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.143235","article-title":"The effects of antimony on Alzheimer's disease-like pathological changes in mice brain","volume":"760","author":"Xu","year":"2021","journal-title":"Sci. Total Environ."},{"issue":"9","key":"10.1016\/j.ecoenv.2025.117736_bib47","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1038\/s41582-019-0228-7","article-title":"Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies","volume":"15","author":"Yamazaki","year":"2019","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.ecoenv.2025.117736_bib48","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2024.1445470","article-title":"Secretase promotes AD progression: simultaneously cleave Notch and APP","volume":"16","author":"Yang","year":"2024","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.ecoenv.2025.117736_bib49","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2024.1351792","article-title":"Selective degradation of hyperphosphorylated tau by proteolysis-targeting chimeras ameliorates cognitive function in Alzheimer's disease model mice","volume":"15","author":"Yao","year":"2024","journal-title":"Front. Pharm."},{"issue":"5","key":"10.1016\/j.ecoenv.2025.117736_bib50","first-page":"4348","article-title":"Prenatal diesel exhaust exposure alters hippocampal synaptic plasticity in offspring","volume":"16","author":"Yu","year":"2024","journal-title":"Aging (Albany NY)"},{"issue":"32","key":"10.1016\/j.ecoenv.2025.117736_bib51","doi-asserted-by":"crossref","first-page":"3082","DOI":"10.1093\/eurheartj\/ehad392","article-title":"A novel prediction model for pulmonary embolism: from dichotomizing algorithms to personalized likelihood","volume":"44","author":"Zelniker","year":"2023","journal-title":"Eur. Heart J."},{"issue":"6","key":"10.1016\/j.ecoenv.2025.117736_bib52","first-page":"760","article-title":"Effects of nanopolystyrene nanoplastic exposure on the development and neurotoxicity of fetal rats during gestation","volume":"38","author":"Zhang","year":"2022","journal-title":"Zhongguo Ying Yong Sheng Li Xue Za Zhi"},{"key":"10.1016\/j.ecoenv.2025.117736_bib53","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.toxlet.2021.09.006","article-title":"Antimony-induced astrocyte activation via mitogen-activated protein kinase activation-dependent CREB phosphorylation","volume":"352","author":"Zheng","year":"2021","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.ecoenv.2025.117736_bib54","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.toxlet.2019.04.004","article-title":"PKA- and Ca(2+)-dependent p38 MAPK\/CREB activation protects against manganese-mediated neuronal apoptosis","volume":"309","author":"Zhu","year":"2019","journal-title":"Toxicol. Lett."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651325000727?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651325000727?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T08:52:47Z","timestamp":1762246367000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651325000727"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":54,"alternative-id":["S0147651325000727"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2025.117736","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exposure to nano-polystyrene during pregnancy leads to Alzheimer's disease-related pathological changes in adult offspring","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2025.117736","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"117736"}}