{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:31:23Z","timestamp":1786987883180,"version":"build-2736575974"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T00:00:00Z","timestamp":1741046400000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82088102"],"award-info":[{"award-number":["82088102"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82171686"],"award-info":[{"award-number":["82171686"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003345","name":"Chinese Academy of Meteorological Sciences","doi-asserted-by":"publisher","award":["2020CXJQ01"],"award-info":[{"award-number":["2020CXJQ01"]}],"id":[{"id":"10.13039\/501100003345","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017950","name":"Shanghai Municipal Health Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010574","name":"China Academy of Space Technology","doi-asserted-by":"publisher","award":["YESS20210294"],"award-info":[{"award-number":["YESS20210294"]}],"id":[{"id":"10.13039\/501100010574","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019018","name":"CAMS Innovation Fund for Medical Sciences","doi-asserted-by":"publisher","award":["2019-I2M-5-064"],"award-info":[{"award-number":["2019-I2M-5-064"]}],"id":[{"id":"10.13039\/501100019018","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFC2700700"],"award-info":[{"award-number":["2021YFC2700700"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC2703500"],"award-info":[{"award-number":["2022YFC2703500"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFC2705700"],"award-info":[{"award-number":["2023YFC2705700"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.ecoenv.2025.118010","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T01:04:48Z","timestamp":1741655088000},"page":"118010","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Associations between fine particulate matter and its constituents and intrahepatic cholestasis of pregnancy"],"prefix":"10.1016","volume":"293","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7381-4940","authenticated-orcid":false,"given":"Cheng","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Zhou","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-Hui","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4496-0228","authenticated-orcid":false,"given":"Jing-Jing","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si-Wei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si-Yue","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1871-8999","authenticated-orcid":false,"given":"Hai-Dong","family":"Kan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0751-1722","authenticated-orcid":false,"given":"Xia","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4344-8019","authenticated-orcid":false,"given":"He-Feng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2293-1792","authenticated-orcid":false,"given":"Yan-Ting","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.ecoenv.2025.118010_bib1","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1002\/hep.26055","article-title":"Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype","volume":"57","author":"Abu-Hayyeh","year":"2013","journal-title":"Hepatology"},{"issue":"6","key":"10.1016\/j.ecoenv.2025.118010_bib2","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2020.8243","article-title":"Association of Air Pollution and Heat Exposure With Preterm Birth, Low Birth Weight, and Stillbirth in the US: A Systematic Review","volume":"3","author":"Bekkar","year":"2020","journal-title":"JAMA Netw. Open"},{"key":"10.1016\/j.ecoenv.2025.118010_bib3","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.ejogrb.2018.10.041","article-title":"Intrahepatic cholestasis of pregnancy: Review of six national and regional guidelines","volume":"231","author":"Bicocca","year":"2018","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"issue":"2","key":"10.1016\/j.ecoenv.2025.118010_bib4","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1164\/ajrccm.159.2.9711068","article-title":"Persistent airway inflammation but accommodated antioxidant and lung function responses after repeated daily exposure to nitrogen dioxide","volume":"159","author":"Blomberg","year":"1999","journal-title":"Am. J. Respir. Crit. Care Med"},{"issue":"10","key":"10.1016\/j.ecoenv.2025.118010_bib5","doi-asserted-by":"crossref","first-page":"e804","DOI":"10.1016\/S2542-5196(22)00200-5","article-title":"Maternal exposure to ambient black carbon particles and their presence in maternal and fetal circulation and organs: an analysis of two independent population-based observational studies","volume":"6","author":"Bongaerts","year":"2022","journal-title":"Lancet Planet Health"},{"key":"10.1016\/j.ecoenv.2025.118010_bib6","doi-asserted-by":"crossref","first-page":"4527","DOI":"10.2147\/JIR.S430730","article-title":"The Role of Inflammation in Cholestatic Liver Injury","volume":"16","author":"Chen","year":"2023","journal-title":"J. Inflamm. Res"},{"issue":"4","key":"10.1016\/j.ecoenv.2025.118010_bib7","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1210\/me.2015-1014","article-title":"Estrogen and Estrogen Receptor-\u03b1-Mediated Transrepression of Bile Salt Export Pump","volume":"29","author":"Chen","year":"2015","journal-title":"Mol. Endocrinol."},{"issue":"1","key":"10.1016\/j.ecoenv.2025.118010_bib8","doi-asserted-by":"crossref","DOI":"10.3390\/toxics7010006","article-title":"Metabolic Syndrome and Air Pollution: A Narrative Review of Their Cardiopulmonary Effects","volume":"7","author":"Clementi","year":"2019","journal-title":"Toxics"},{"issue":"2","key":"10.1016\/j.ecoenv.2025.118010_bib9","doi-asserted-by":"crossref","first-page":"G449","DOI":"10.1152\/ajpgi.00508.2002","article-title":"Estradiol-17beta-D-glucuronide induces endocytic internalization of Bsep in rats","volume":"285","author":"Crocenzi","year":"2003","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"issue":"11","key":"10.1016\/j.ecoenv.2025.118010_bib10","doi-asserted-by":"crossref","first-page":"3483","DOI":"10.1021\/acssensors.0c01524","article-title":"A Membrane-free Liver-Gut-on-Chip Platform for the Assessment on Dysregulated Mechanisms of Cholesterol and Bile Acid Metabolism Induced by PM(2.5)","volume":"5","author":"Duan","year":"2020","journal-title":"ACS Sens"},{"issue":"4","key":"10.1016\/j.ecoenv.2025.118010_bib11","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/OGX.0000000000001116","article-title":"Climate Change and Pregnancy: Risks, Mitigation, Adaptation, and Resilience","volume":"78","author":"Fan","year":"2023","journal-title":"Obstet. Gynecol. Surv."},{"issue":"11","key":"10.1016\/j.ecoenv.2025.118010_bib12","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.tips.2009.08.001","article-title":"Bile-acid-activated receptors: targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders","volume":"30","author":"Fiorucci","year":"2009","journal-title":"Trends Pharm. Sci."},{"issue":"1","key":"10.1016\/j.ecoenv.2025.118010_bib13","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.cld.2015.08.010","article-title":"New Insights on Intrahepatic Cholestasis of Pregnancy","volume":"20","author":"Floreani","year":"2016","journal-title":"Clin. Liver Dis."},{"issue":"5","key":"10.1016\/j.ecoenv.2025.118010_bib14","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1002\/hep.31494","article-title":"Bidirectional Role of NLRP3 During Acute and Chronic Cholestatic Liver Injury","volume":"73","author":"Frissen","year":"2021","journal-title":"Hepatology"},{"issue":"2","key":"10.1016\/j.ecoenv.2025.118010_bib15","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1053\/jhep.2003.50317","article-title":"Effects of proinflammatory cytokines on rat organic anion transporters during toxic liver injury and cholestasis","volume":"38","author":"Geier","year":"2003","journal-title":"Hepatology"},{"issue":"1","key":"10.1016\/j.ecoenv.2025.118010_bib16","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/0168-8278(89)90079-2","article-title":"Intrahepatic cholestasis of pregnancy in twin pregnancies","volume":"9","author":"Gonzalez","year":"1989","journal-title":"J. Hepatol."},{"issue":"3","key":"10.1016\/j.ecoenv.2025.118010_bib17","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.jhep.2021.10.016","article-title":"Exposure to air pollution is associated with an increased risk of metabolic dysfunction-associated fatty liver disease","volume":"76","author":"Guo","year":"2022","journal-title":"J. Hepatol."},{"key":"10.1016\/j.ecoenv.2025.118010_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2022.108747","article-title":"New insights into the treatment mechanisms of Vitamin D on PM(2.5)-induced toxicity and inflammation in mouse renal tubular epithelial cells","volume":"108","author":"Huang","year":"2022","journal-title":"Int Immunopharmacol."},{"issue":"6","key":"10.1016\/j.ecoenv.2025.118010_bib19","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1093\/aje\/kwaa259","article-title":"Air Pollution and Risk of Placental Abruption: A Study of Births in New York City, 2008-2014","volume":"190","author":"Huang","year":"2021","journal-title":"Am. J. Epidemiol."},{"issue":"5","key":"10.1016\/j.ecoenv.2025.118010_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/nu15051182","article-title":"Effects of Climate, Sun Exposure, and Dietary Intake on Vitamin D Concentrations in Pregnant Women: A Population-Based Study","volume":"15","author":"Huang","year":"2023","journal-title":"Nutrients"},{"key":"10.1016\/j.ecoenv.2025.118010_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.112762","article-title":"Research on adaption to air pollution in Chinese cities: Evidence from social media-based health sensing","volume":"210","author":"Ji","year":"2022","journal-title":"Environ. Res"},{"issue":"1","key":"10.1016\/j.ecoenv.2025.118010_bib22","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1586\/1744666X.2016.1101344","article-title":"Immunological basis in the pathogenesis of intrahepatic cholestasis of pregnancy","volume":"12","author":"Larson","year":"2016","journal-title":"Expert Rev. Clin. Immunol."},{"issue":"Pt 3","key":"10.1016\/j.ecoenv.2025.118010_bib23","article-title":"Interactive effects of ambient air pollution and sunshine duration on the risk of intrahepatic cholestasis of pregnancy","volume":"215","author":"Li","year":"2022","journal-title":"Environ. Res"},{"issue":"12","key":"10.1016\/j.ecoenv.2025.118010_bib24","doi-asserted-by":"crossref","first-page":"4930","DOI":"10.1021\/acs.est.2c06573","article-title":"Effects of Particulate Matter on the Risk of Gestational Hypertensive Disorders and Their Progression","volume":"57","author":"Li","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ecoenv.2025.118010_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.actatropica.2024.107193","article-title":"An association between PM(2.5) components and respiratory infectious diseases: A China's mainland-based study","volume":"254","author":"Li","year":"2024","journal-title":"Acta Trop."},{"issue":"22","key":"10.1016\/j.ecoenv.2025.118010_bib26","doi-asserted-by":"crossref","first-page":"16517","DOI":"10.1021\/acs.est.2c06510","article-title":"Tracking Daily Concentrations of PM(2.5) Chemical Composition in China since 2000","volume":"56","author":"Liu","year":"2022","journal-title":"Environ. Sci. Technol."},{"issue":"11","key":"10.1016\/j.ecoenv.2025.118010_bib27","article-title":"Bile Acids in Intrahepatic Cholestasis of Pregnancy","volume":"12","author":"Majsterek","year":"2022","journal-title":"Diagn. (Basel)"},{"issue":"2","key":"10.1016\/j.ecoenv.2025.118010_bib28","doi-asserted-by":"crossref","first-page":"243","DOI":"10.2337\/dc14-2143","article-title":"The metabolic profile of intrahepatic cholestasis of pregnancy is associated with impaired glucose tolerance, dyslipidemia, and increased fetal growth","volume":"38","author":"Martineau","year":"2015","journal-title":"Diabetes Care"},{"key":"10.1016\/j.ecoenv.2025.118010_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.rse.2020.112203","article-title":"Estimating PM(2.5) concentrations in Northeastern China with full spatiotemporal coverage, 2005-2016","volume":"253","author":"Meng","year":"2021","journal-title":"Remote Sens Environ."},{"key":"10.1016\/j.ecoenv.2025.118010_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.prostaglandins.2019.106399","article-title":"Role of sphingolipids in the pathogenesis of intrahepatic cholestasis","volume":"147","author":"Mikucka-Niczyporuk","year":"2020","journal-title":"Prostaglandins Other Lipid Mediat"},{"issue":"3","key":"10.1016\/j.ecoenv.2025.118010_bib31","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1007\/s00404-020-05456-y","article-title":"Intrahepatic cholestasis of pregnancy as a risk factor for preeclampsia","volume":"301","author":"Mor","year":"2020","journal-title":"Arch. Gynecol. Obstet."},{"issue":"10174","key":"10.1016\/j.ecoenv.2025.118010_bib32","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/S0140-6736(18)31877-4","article-title":"Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses","volume":"393","author":"Ovadia","year":"2019","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.ecoenv.2025.118010_bib33","article-title":"The role of steroid hormones in the development of intrahepatic cholestasis of pregnancy","volume":"64","author":"Pa\u0159\u00edzek","year":"2015","journal-title":"Physiol. Res"},{"key":"10.1016\/j.ecoenv.2025.118010_bib34","doi-asserted-by":"crossref","first-page":"244","DOI":"10.3389\/fimmu.2014.00244","article-title":"Innate immune system and preeclampsia","volume":"5","author":"Perez-Sepulveda","year":"2014","journal-title":"Front Immunol."},{"issue":"16","key":"10.1016\/j.ecoenv.2025.118010_bib35","doi-asserted-by":"crossref","first-page":"11473","DOI":"10.1021\/acs.est.2c01103","article-title":"Prenatal Exposure to PM(2.5) and Its Specific Components and Risk of Hypertensive Disorders in Pregnancy: A Nationwide Cohort Study in China","volume":"56","author":"Shen","year":"2022","journal-title":"Environ. Sci. Technol."},{"issue":"15","key":"10.1016\/j.ecoenv.2025.118010_bib36","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph17155441","article-title":"How Do Economic Growth, Urbanization, and Industrialization Affect Fine Particulate Matter Concentrations? An Assessment in Liaoning Province, China","volume":"17","author":"Shi","year":"2020","journal-title":"Int J. Environ. Res Public Health"},{"key":"10.1016\/j.ecoenv.2025.118010_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.132915","article-title":"A Chinese longitudinal maternity cohort study (2013-2021) on intrahepatic cholestasis phenotypes: Risk associations from environmental exposure to adverse pregnancy outcomes","volume":"463","author":"Sun","year":"2024","journal-title":"J. Hazard Mater."},{"issue":"1","key":"10.1016\/j.ecoenv.2025.118010_bib38","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1007\/s12072-023-10604-y","article-title":"Intrahepatic cholestasis of pregnancy: insights into pathogenesis and advances in omics studies","volume":"18","author":"Tang","year":"2024","journal-title":"Hepatol. Int"},{"issue":"1","key":"10.1016\/j.ecoenv.2025.118010_bib39","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1289\/ehp.0900550","article-title":"Baseline repeated measures from controlled human exposure studies: associations between ambient air pollution exposure and the systemic inflammatory biomarkers IL-6 and fibrinogen","volume":"118","author":"Thompson","year":"2010","journal-title":"Environ. Health Perspect."},{"issue":"2","key":"10.1016\/j.ecoenv.2025.118010_bib40","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/s10653-023-01794-3","article-title":"Exposure to PM(2.5) and its five constituents is associated with the incidence of type 2 diabetes mellitus: a prospective cohort study in northwest China","volume":"46","author":"Wang","year":"2024","journal-title":"Environ. Geochem Health"},{"issue":"3","key":"10.1016\/j.ecoenv.2025.118010_bib41","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.ajpath.2023.11.016","article-title":"Vitamin D Receptor Activation Reduces Hepatic Inflammation via Enhancing Macrophage Autophagy in Cholestatic Mice","volume":"194","author":"Wen","year":"2024","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.ecoenv.2025.118010_bib42","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.envint.2017.03.026","article-title":"Ambient air pollution and low birth weight - are some women more vulnerable than others?","volume":"104","author":"Westergaard","year":"2017","journal-title":"Environ. Int"},{"key":"10.1016\/j.ecoenv.2025.118010_bib43","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/6679322","article-title":"Molecular Pathogenesis of Intrahepatic Cholestasis of Pregnancy","volume":"2021","author":"Xiao","year":"2021","journal-title":"Can. J. Gastroenterol. Hepatol."},{"issue":"2","key":"10.1016\/j.ecoenv.2025.118010_bib44","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1007\/s10753-018-0928-y","article-title":"1,25-Dihydroxy Vitamin D(3) Attenuates the Oxidative Stress-Mediated Inflammation Induced by PM(2.5)via the p38\/NF-\u03baB\/NLRP3 Pathway","volume":"42","author":"Xin","year":"2019","journal-title":"Inflammation"},{"key":"10.1016\/j.ecoenv.2025.118010_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105880","article-title":"Fine particular matter and its constituents in air pollution and gestational diabetes mellitus","volume":"142","author":"Yu","year":"2020","journal-title":"Environ. Int"},{"issue":"10","key":"10.1016\/j.ecoenv.2025.118010_bib46","first-page":"4357","article-title":"Impact of particulate matter 2.5 on the liver function of mice","volume":"27","author":"Zhang","year":"2023","journal-title":"Eur. Rev. Med Pharm. Sci."},{"issue":"10","key":"10.1016\/j.ecoenv.2025.118010_bib47","doi-asserted-by":"crossref","first-page":"3803","DOI":"10.1021\/acs.chemrev.5b00067","article-title":"Formation of urban fine particulate matter","volume":"115","author":"Zhang","year":"2015","journal-title":"Chem. Rev."},{"issue":"1","key":"10.1016\/j.ecoenv.2025.118010_bib48","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s12884-024-06248-x","article-title":"Maternal and neonatal outcomes of intrahepatic cholestasis of pregnancy after in vitro fertilization","volume":"24","author":"Zhu","year":"2024","journal-title":"BMC Pregnancy Childbirth"}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014765132500346X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014765132500346X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:07:06Z","timestamp":1777489626000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S014765132500346X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":48,"alternative-id":["S014765132500346X"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2025.118010","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Associations between fine particulate matter and its constituents and intrahepatic cholestasis of pregnancy","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2025.118010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"118010"}}