{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T23:26:29Z","timestamp":1790724389663,"version":"4.1.0"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T00:00:00Z","timestamp":1755648000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100018546","name":"Postdoctoral Innovation Project of Shandong Province","doi-asserted-by":"publisher","award":["SDCX-ZG-202503121"],"award-info":[{"award-number":["SDCX-ZG-202503121"]}],"id":[{"id":"10.13039\/501100018546","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82371084"],"award-info":[{"award-number":["82371084"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82401265"],"award-info":[{"award-number":["82401265"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007928","name":"Ningbo Municipal Bureau of Science and Technology","doi-asserted-by":"publisher","award":["2024Y50"],"award-info":[{"award-number":["2024Y50"]}],"id":[{"id":"10.13039\/501100007928","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.ecoenv.2025.118921","type":"journal-article","created":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T15:39:21Z","timestamp":1755963561000},"page":"118921","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Blue light induces corneal epithelial damage by activating the NLRP3 inflammasome pathway"],"prefix":"10.1016","volume":"303","author":[{"given":"Jiayun","family":"Ge","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0825-9719","authenticated-orcid":false,"given":"Qianjie","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutong","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuhong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyue","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanqing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinhao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongjie","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhitong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuangqi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3786-9644","authenticated-orcid":false,"given":"Xiuyi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianping","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2025.118921_bib1","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1089\/ars.2014.5994","article-title":"Redox regulation of NLRP3 inflammasomes: ROS as trigger or effector?","volume":"22","author":"Abais","year":"2015","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.ecoenv.2025.118921_bib2","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.exer.2022.108978","article-title":"Filtering blue light mitigates the deleterious effects induced by the oxidative stress in human retinal pigment epithelial cells","volume":"217","author":"Abdouh","year":"2022","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.ecoenv.2025.118921_bib3","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1007\/s00204-019-02409-6","article-title":"Toxicity of blue led light and A2E is associated to mitochondrial dynamics impairment in ARPE-19 cells: implications for age-related macular degeneration","volume":"93","author":"Alaimo","year":"2019","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.ecoenv.2025.118921_bib4","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s12974-024-03055-1","article-title":"The contribution of pattern recognition receptor signalling in the development of age related macular degeneration: the role of toll-like-receptors and the NLRP3-inflammasome","volume":"21","author":"Brandli","year":"2024","journal-title":"J. Neuroinflamm."},{"key":"10.1016\/j.ecoenv.2025.118921_bib5","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1007\/s00109-015-1275-1","article-title":"Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage","volume":"93","author":"Brandstetter","year":"2015","journal-title":"J. Mol. Med."},{"key":"10.1016\/j.ecoenv.2025.118921_bib6","article-title":"The role of the PI3K\/AKT signalling pathway in the corneal epithelium: recent updates","volume":"13","author":"Chen","year":"2022","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.ecoenv.2025.118921_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2023.108448","article-title":"Blue light impairs cornea and corneal wound healing by downregulating VCAM1 partly","volume":"26","author":"Chen","year":"2023","journal-title":"Iscience"},{"key":"10.1016\/j.ecoenv.2025.118921_bib8","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1038\/eye.2015.221","article-title":"Light pollution: the possible consequences of excessive illumination on retina","volume":"30","author":"Cont\u00edn","year":"2016","journal-title":"Eye"},{"key":"10.1016\/j.ecoenv.2025.118921_bib9","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.redox.2018.101093","article-title":"Calcitriol inhibits ROS-NLRP3-IL-1\u03b2 signaling axis via activation of Nrf2-antioxidant signaling in hyperosmotic stress stimulated human corneal epithelial cells","volume":"21","author":"Dai","year":"2019","journal-title":"Redox Biol."},{"key":"10.1016\/j.ecoenv.2025.118921_bib10","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1146\/annurev-immunol-081022-021207","article-title":"Structural mechanisms of NLRP3 inflammasome assembly and activation","volume":"41","author":"Fu","year":"2023","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.ecoenv.2025.118921_bib11","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.jtos.2024.09.007","article-title":"Recent advances in NLRP3 inflammasome in corneal diseases: preclinical insights and therapeutic implications","volume":"34","author":"Ge","year":"2024","journal-title":"Ocul. Surf."},{"key":"10.1016\/j.ecoenv.2025.118921_bib12","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.jtos.2024.09.007","article-title":"Recent advances in NLRP3 inflammasome in corneal diseases: preclinical insights and therapeutic implications","volume":"34","author":"Ge","year":"2024","journal-title":"Ocul. Surf."},{"key":"10.1016\/j.ecoenv.2025.118921_bib13","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.jcis.2022.02.115","article-title":"Seeking eye protection from biomass: carbon dot-based optical blocking films with adjustable levels of blue light blocking","volume":"617","author":"Han","year":"2022","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.ecoenv.2025.118921_bib14","doi-asserted-by":"crossref","DOI":"10.1038\/nature10809","article-title":"Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity","volume":"482","author":"Henao-Mejia","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.ecoenv.2025.118921_bib15","doi-asserted-by":"crossref","first-page":"11","DOI":"10.3390\/biomedicines11082321","article-title":"Induction of skin cancer by long-term blue light irradiation","volume":"11","author":"Hiramoto","year":"2023","journal-title":"Biomedicines"},{"key":"10.1016\/j.ecoenv.2025.118921_bib16","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2016.363","article-title":"Knockout of Ccr2 alleviates photoreceptor cell death in rodent retina exposed to chronic blue light","volume":"7","author":"Hu","year":"2016","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.ecoenv.2025.118921_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.165500","article-title":"Dibutyl phthalate induces liver fibrosis via p38MAPK\/NF-\u03baB\/NLRP3-mediated pyroptosis","volume":"897","author":"Huo","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2025.118921_bib18","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.exer.2024.110019","article-title":"The role of the SIRT1\/NF-\u03baB\/NLRP3 pathway in the pyroptosis of lens epithelial cells under shortwave blue light radiation","volume":"246","author":"Ji","year":"2024","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.ecoenv.2025.118921_bib19","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3390\/ijms231911341","article-title":"Melatonin type 2 receptor activation regulates blue light Exposure-Induced mouse corneal epithelial damage by modulating impaired autophagy and apoptosis","volume":"23","author":"Jin","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ecoenv.2025.118921_bib20","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.ecoenv.2024.117345","article-title":"The ROS\/AKT\/S6K axis induces corneal epithelial dysfunctions under LED blue light exposure","volume":"287","author":"Jin","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2025.118921_bib21","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.preteyeres.2021.101011","article-title":"Regenerative therapy for the cornea","volume":"87","author":"Kumar","year":"2022","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.ecoenv.2025.118921_bib22","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1002\/advs.202400230","article-title":"Polydopamine nanoparticles as mimicking RPE melanin for the protection of retinal cells against blue Light-Induced phototoxicity","volume":"11","author":"Kwon","year":"2024","journal-title":"Adv. Sci."},{"key":"10.1016\/j.ecoenv.2025.118921_bib23","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0167671","article-title":"Influence of light emitting diode-derived blue light overexposure on mouse ocular surface (vol 11, e0161041, 2016)","author":"Lee","year":"2016","journal-title":"PLOS One"},{"key":"10.1016\/j.ecoenv.2025.118921_bib24","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.yexcr.2019.07.001","article-title":"NLRP3 inflammasome inhibition attenuates cisplatin-induced renal fibrosis by decreasing oxidative stress and inflammation","volume":"383","author":"Li","year":"2019","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.ecoenv.2025.118921_bib25","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.bcp.2023.115620","article-title":"The mTOR signalling in corneal diseases: a recent update","volume":"213","author":"Li","year":"2023","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ecoenv.2025.118921_bib26","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ecoenv.2024.117643","article-title":"Lactic acid contributes to the emergence of depression-like behaviors triggered by blue light exposure during sleep","volume":"289","author":"Li","year":"2025","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2025.118921_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2021.108654","article-title":"N-acetylcysteine alleviates ocular surface damage in STZ-induced diabetic mice by inhibiting the ROS\/NLRP3\/Caspase-1\/IL-1\u03b2 signaling pathway","volume":"209","author":"Liu","year":"2021","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.ecoenv.2025.118921_bib28","first-page":"283","article-title":"Construction of the ceRNA network in the progression of acute myocardial infarction","volume":"12","author":"Liu","year":"2022","journal-title":"Am. J. Cardiovasc Dis."},{"key":"10.1016\/j.ecoenv.2025.118921_bib29","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1124\/pharmrev.122.000629","article-title":"Pharmacological inhibition of the NLRP3 inflammasome: structure, molecular activation, and Inhibitor-NLRP3 interaction","volume":"75","author":"Ma","year":"2023","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.ecoenv.2025.118921_bib30","doi-asserted-by":"crossref","first-page":"3955","DOI":"10.1242\/jcs.207365","article-title":"Inflammasome activation and assembly at a glance","volume":"130","author":"Malik","year":"2017","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.ecoenv.2025.118921_bib31","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.arr.2023.101954","article-title":"The central role of the NLRP3 inflammasome pathway in the pathogenesis of age-related diseases in the eye and the brain","volume":"88","author":"Maran","year":"2023","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.ecoenv.2025.118921_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.preteyeres.2015.07.001","article-title":"Corneal structure and transparency","volume":"49","author":"Meek","year":"2015","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.ecoenv.2025.118921_bib33","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.scitotenv.2020.139334","article-title":"Investigation on entraining and enhancing human circadian rhythm in closed environments using daylight -like LED mixed lighting","volume":"732","author":"Nie","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2025.118921_bib34","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.biopha.2020.110577","article-title":"Mechanisms of blue light-induced eye hazard and protective measures: a review","volume":"130","author":"Ouyang","year":"2020","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.ecoenv.2025.118921_bib35","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.mam.2022.101100","article-title":"The human inflammasomes","volume":"88","author":"Paerewijck","year":"2022","journal-title":"Mol. Asp. Med."},{"key":"10.1016\/j.ecoenv.2025.118921_bib36","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.nanoen.2019.03.043","article-title":"Ultraviolet to blue blocking and wavelength convertible films using carbon dots for interrupting eye damage caused by general lighting","volume":"60","author":"Park","year":"2019","journal-title":"Nano Energy"},{"key":"10.1016\/j.ecoenv.2025.118921_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2020.100904","article-title":"Corneal endothelial dysfunction: evolving understanding and treatment options","volume":"82","author":"Price","year":"2021","journal-title":"Prog. Retin Eye Res."},{"key":"10.1016\/j.ecoenv.2025.118921_bib38","doi-asserted-by":"crossref","first-page":"S86","DOI":"10.1097\/ICO.0000000000001717","article-title":"Implications of inflammasomes in human diseases: NLRP3 inflammasome and animal models","volume":"37","author":"Sakimoto","year":"2018","journal-title":"Cornea"},{"key":"10.1016\/j.ecoenv.2025.118921_bib39","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.exer.2023.109748","article-title":"The role of the JAK\/STAT3 signaling pathway in acquired corneal diseases","volume":"238","author":"Song","year":"2024","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.ecoenv.2025.118921_bib40","doi-asserted-by":"crossref","first-page":"809","DOI":"10.7150\/ijbs.63219","article-title":"The advanced glycation end-products (AGEs)\/ROS\/NLRP3 inflammasome axis contributes to delayed diabetic corneal wound healing and nerve regeneration","volume":"18","author":"Wan","year":"2022","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.ecoenv.2025.118921_bib41","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.lfs.2019.04.031","article-title":"NLRP3 inflammasome activates interleukin-23\/interleukin-17 axis during ischaemia-reperfusion injury in cerebral ischaemia in mice","volume":"227","author":"Wang","year":"2019","journal-title":"Life Sci."},{"key":"10.1016\/j.ecoenv.2025.118921_bib42","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.exer.2021.108668","article-title":"Topical calcitriol application promotes diabetic corneal wound healing and reinnervation through inhibiting NLRP3 inflammasome activation","volume":"209","author":"Wang","year":"2021","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.ecoenv.2025.118921_bib43","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.jphotobiol.2023.112654","article-title":"Long-term blue light exposure impairs mitochondrial dynamics in the retina in light-induced retinal degeneration in vivo and in vitro","volume":"240","author":"Wang","year":"2023","journal-title":"J. Photochem. Photobiol. B Biol."},{"key":"10.1016\/j.ecoenv.2025.118921_bib44","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.phymed.2024.156260","article-title":"Salvianolic acid b alleviated myocardial ischemia-reperfusion injury via modulating SIRT3-mediated crosstalk between mitochondrial ROS and NLRP3","volume":"136","author":"Wei","year":"2025","journal-title":"Phytomedicine"},{"key":"10.1016\/j.ecoenv.2025.118921_bib45","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/s41420-024-01935-2","article-title":"Methylation in cornea and corneal diseases: a systematic review","volume":"10","author":"Xia","year":"2024","journal-title":"Cell Death Discov."},{"key":"10.1016\/j.ecoenv.2025.118921_bib46","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jphotobiol.2024.112908","article-title":"Blue light induced ferroptosis via STAT3\/GPX4\/SLC7A11\/FTH1 in conjunctiva epithelium in vivo and in vitro","volume":"255","author":"Yang","year":"2024","journal-title":"J. Photochem. Photobiol. B Biol."},{"key":"10.1016\/j.ecoenv.2025.118921_bib47","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3390\/ijms252011243","article-title":"A selective melatonin 2 receptor agonist, IIK7, relieves blue Light-Induced corneal damage by modulating the process of autophagy and apoptosis","volume":"25","author":"Yoon","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ecoenv.2025.118921_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2021.101039","article-title":"The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas","volume":"89","author":"Yu","year":"2022","journal-title":"Prog. Retin Eye Res."},{"key":"10.1016\/j.ecoenv.2025.118921_bib49","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1080\/02713683.2018.1518458","article-title":"Photo-Oxidative Blue-Light stimulation in retinal pigment epithelium cells promotes exosome secretion and increases the activity of the NLRP3 inflammasome","volume":"44","author":"Zhang","year":"2019","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.ecoenv.2025.118921_bib50","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/s41590-022-01355-3","article-title":"Distinct changes in endosomal composition promote NLRP3 inflammasome activation","volume":"24","author":"Zhang","year":"2023","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.ecoenv.2025.118921_bib51","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1080\/02713683.2024.2419684","article-title":"Effects of miR-21\/NLRP3 on blue Light-Induced retinal neurodegeneration in mice","volume":"50","author":"Zhang","year":"2025","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.ecoenv.2025.118921_bib52","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1038\/nature09663","article-title":"A role for mitochondria in NLRP3 inflammasome activation","volume":"469","author":"Zhou","year":"2011","journal-title":"Nature"}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651325012667?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651325012667?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T13:29:26Z","timestamp":1777123766000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651325012667"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":52,"alternative-id":["S0147651325012667"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2025.118921","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Blue light induces corneal epithelial damage by activating the NLRP3 inflammasome pathway","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2025.118921","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"118921"}}