{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T14:25:23Z","timestamp":1790087123463,"version":"4.0.1"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011840","name":"Shantou University Medical College","doi-asserted-by":"publisher","award":["510858080"],"award-info":[{"award-number":["510858080"]}],"id":[{"id":"10.13039\/501100011840","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Guangdong Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["2023A1515011878"],"award-info":[{"award-number":["2023A1515011878"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Guangdong Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["2023A1515012357"],"award-info":[{"award-number":["2023A1515012357"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.ecoenv.2025.119240","type":"journal-article","created":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T03:54:21Z","timestamp":1760846061000},"page":"119240","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Bisphenol S as an emerging osteotoxicant: Mechanistic insights from osteoblasts and zebrafish models"],"prefix":"10.1016","volume":"305","author":[{"given":"Xiaoling","family":"Shi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caixia","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kusheng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9403-7319","authenticated-orcid":false,"given":"Wenlong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2025.119240_bib1","doi-asserted-by":"crossref","first-page":"3250","DOI":"10.1039\/C7FO00859G","article-title":"The protective effect of acerola (Malpighia emarginata) against oxidative damage in human dermal fibroblasts through the improvement of antioxidant enzyme activity and mitochondrial functionality","volume":"8","author":"Alvarez-Suarez","year":"2017","journal-title":"Food Funct."},{"key":"10.1016\/j.ecoenv.2025.119240_bib2","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1007\/s12403-023-00596-3","article-title":"Exposure to environmental chemicals and human bone health; a systematic review and Meta-Analysis","volume":"16","author":"Baradaran Mahdavi","year":"2023","journal-title":"Expo. Health"},{"key":"10.1016\/j.ecoenv.2025.119240_bib3","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.scitotenv.2017.10.252","article-title":"The occurrence and source identification of bisphenol compounds in wastewaters","volume":"616-617","author":"\u010cesen","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2025.119240_bib4","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1038\/cr.2016.100","article-title":"Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis","volume":"26","author":"Chen","year":"2016","journal-title":"Cell Res."},{"key":"10.1016\/j.ecoenv.2025.119240_bib5","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1002\/jcb.26238","article-title":"Pseudoshikonin I enhances osteoblast differentiation by stimulating Runx2 and osterix","volume":"119","author":"Choi","year":"2017","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.ecoenv.2025.119240_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.122499","article-title":"Exposure to the aryl hydrocarbon receptor agonist dioxin disrupts formation of the muscle, nerves, and vasculature in the developing jaw","volume":"337","author":"Cintr\u00f3n-Rivera","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2025.119240_bib7","article-title":"Evolution and development of the fish jaw skeleton","volume":"8","author":"DeLaurier","year":"2018","journal-title":"WIREs Dev. Biol."},{"key":"10.1016\/j.ecoenv.2025.119240_bib8","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1002\/jbmr.4256","article-title":"Skeletal biology and disease modeling in zebrafish","volume":"36","author":"Dietrich","year":"2020","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.ecoenv.2025.119240_bib9","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2016.69","article-title":"Dihydroartemisinin attenuates lipopolysaccharide-induced osteoclastogenesis and bone loss via the mitochondria-dependent apoptosis pathway","volume":"7","author":"Dou","year":"2016","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.ecoenv.2025.119240_bib10","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.tiv.2015.03.014","article-title":"Genome-wide gene expression profiling of low-dose, long-term exposure of human osteosarcoma cells to bisphenol a and its analogs bisphenols AF and s","volume":"29","author":"Fic","year":"2015","journal-title":"Toxicol. Vitr."},{"key":"10.1016\/j.ecoenv.2025.119240_bib11","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1196\/annals.1378.009","article-title":"Alterations in mRNA expression of Apoptosis-related genes BCL2, BAX, FAS, Caspase-3, and the novel member BCL2L12 after treatment of human leukemic cell line HL60 with the antineoplastic agent etoposide","volume":"1090","author":"Floros","year":"2007","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.ecoenv.2025.119240_bib12","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.1007\/s00204-023-03523-2","article-title":"Effects of bisphenol F, bisphenol S, and bisphenol AF on cultured human osteoblasts","volume":"97","author":"Garc\u00eda-Recio","year":"2023","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.ecoenv.2025.119240_bib13","doi-asserted-by":"crossref","DOI":"10.3390\/genes15111453","article-title":"Gene expression modulation of markers involved in bone formation and resorption by bisphenol A, bisphenol F, bisphenol S, and bisphenol AF","volume":"15","author":"Garc\u00eda-Recio","year":"2024","journal-title":"Genes"},{"key":"10.1016\/j.ecoenv.2025.119240_bib14","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.chemosphere.2018.10.218","article-title":"Neurobehavioral effects of bisphenol s exposure in early life stages of zebrafish larvae (Danio rerio)","volume":"217","author":"Gu","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2025.119240_bib15","article-title":"The possible molecular mechanisms of bisphenol a action on porcine early embryonic development","volume":"7","author":"Guo","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ecoenv.2025.119240_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.140401","article-title":"Transgenerational effects of BDE-47 to zebrafish based on histomorphometry and toxicogenomic analyses","volume":"344","author":"Huang","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2025.119240_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.161702","article-title":"Comparative pharyngeal cartilage developmental toxicity of bisphenol A, bisphenol s and bisphenol AF to zebrafish (Danio rerio) larvae: a combination of morphometry and global transcriptome analyses","volume":"868","author":"Huang","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2025.119240_bib18","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.lfs.2013.07.020","article-title":"Bisphenol a reduces differentiation and stimulates apoptosis of osteoclasts and osteoblasts","volume":"93","author":"Hwang","year":"2013","journal-title":"Life Sci."},{"key":"10.1016\/j.ecoenv.2025.119240_bib19","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.mito.2006.11.026","article-title":"Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage","volume":"7","author":"Indo","year":"2007","journal-title":"Mitochondrion"},{"key":"10.1016\/j.ecoenv.2025.119240_bib20","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1093\/toxsci\/kfab145","article-title":"Effects of bisphenols A, AF, and s on endochondral ossification and the transcriptome of murine limb buds","volume":"187","author":"Iskandarani","year":"2022","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.ecoenv.2025.119240_bib21","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1021\/acs.est.7b03958","article-title":"Occurrence and partitioning of bisphenol analogues in Adults\u2019 blood from China","volume":"52","author":"Jin","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ecoenv.2025.119240_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2019.113779","article-title":"Bisphenol analogue concentrations in human breast milk and their associations with postnatal infant growth","volume":"259","author":"Jin","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2025.119240_bib23","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.tox.2003.12.002","article-title":"Effects of phytoestrogens and environmental estrogens on osteoblastic differentiation in MC3T3-E1 cells","volume":"196","author":"Kanno","year":"2004","journal-title":"Toxicology"},{"key":"10.1016\/j.ecoenv.2025.119240_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2024.114652","article-title":"Inhibition of reactive oxygen species generation by N-Acetyl cysteine can mitigate Male germ cell toxicity induced by bisphenol analogs","volume":"188","author":"Kim","year":"2024","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.ecoenv.2025.119240_bib25","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1073\/pnas.1417731112","article-title":"Low-dose exposure to bisphenol a and replacement bisphenol s induces precocious hypothalamic neurogenesis in embryonic zebrafish","volume":"112","author":"Kinch","year":"2015","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.ecoenv.2025.119240_bib26","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.brainresrev.2007.06.023","article-title":"Role of the neural crest in face and brain development","volume":"55","author":"Le Douarin","year":"2007","journal-title":"Brain Res. Rev."},{"key":"10.1016\/j.ecoenv.2025.119240_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2022.153408","article-title":"Evaluation of toxicological effects of bisphenol s with an in vitro human bone marrow mesenchymal stem cell: implications for bone health","volume":"484","author":"Li","year":"2023","journal-title":"Toxicology"},{"key":"10.1016\/j.ecoenv.2025.119240_bib28","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s10495-022-01807-z","article-title":"Pyroptosis in bone loss","volume":"28","author":"Li","year":"2023","journal-title":"Apoptosis"},{"key":"10.1016\/j.ecoenv.2025.119240_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.115665","article-title":"Effects of prenatal single and mixed bisphenol exposure on bone mineral density in preschool children: a population-based prospective cohort study","volume":"267","author":"Liang","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2025.119240_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2021.112388","article-title":"Mitophagy and apoptosis mediated by ROS participate in AlCl3-induced MC3T3-E1 cell dysfunction","volume":"155","author":"Liu","year":"2021","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.ecoenv.2025.119240_bib31","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s10735-020-09874-9","article-title":"Oxidative stress induced pyroptosis leads to osteogenic dysfunction of MG63 cells","volume":"51","author":"Liu","year":"2020","journal-title":"J. Mol. Histol."},{"key":"10.1016\/j.ecoenv.2025.119240_bib32","doi-asserted-by":"crossref","first-page":"7880","DOI":"10.18632\/aging.102295","article-title":"Mechanisms of ROS-induced mitochondria-dependent apoptosis underlying liquid storage of goat spermatozoa","volume":"11","author":"Liu","year":"2019","journal-title":"Aging"},{"key":"10.1016\/j.ecoenv.2025.119240_bib33","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using Real-Time quantitative PCR and the 2\u2212\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.ecoenv.2025.119240_bib34","doi-asserted-by":"crossref","first-page":"3221","DOI":"10.1007\/s00018-016-2223-0","article-title":"Role of Nrf2\/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism","volume":"73","author":"Loboda","year":"2016","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.ecoenv.2025.119240_bib35","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.envres.2019.03.038","article-title":"Perinatal exposure to Bisphenol S (BPS) promotes obesity development by interfering with lipid and glucose metabolism in Male mouse offspring","volume":"173","author":"Meng","year":"2019","journal-title":"Environ. Res."},{"key":"10.1016\/j.ecoenv.2025.119240_bib36","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.ajodo.2015.03.023","article-title":"Interleukin-17 is involved in orthodontically induced inflammatory root resorption in dental pulp cells","volume":"148","author":"Nakano","year":"2015","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"10.1016\/j.ecoenv.2025.119240_bib37","doi-asserted-by":"crossref","DOI":"10.3390\/toxics10060287","article-title":"The mixture of Bisphenol-A and its substitutes Bisphenol-S and Bisphenol-F exerts obesogenic activity on human Adipose-Derived stem cells","volume":"10","author":"Reina-P\u00e9rez","year":"2022","journal-title":"Toxics"},{"key":"10.1016\/j.ecoenv.2025.119240_bib38","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1002\/jemt.24289","article-title":"Bisphenol s exposure promotes cell apoptosis and mitophagy in murine osteocytes by regulating mtROS signaling","volume":"86","author":"Shan","year":"2023","journal-title":"Microsc. Res. Tech."},{"key":"10.1016\/j.ecoenv.2025.119240_bib39","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.tibs.2016.10.004","article-title":"Pyroptosis: Gasdermin-mediated programmed necrotic cell death","volume":"42","author":"Shi","year":"2017","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.ecoenv.2025.119240_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2024.123731","article-title":"Preliminary investigation into the impact of BPA on osteoblast activity and bone development: in vitro and in vivo models","volume":"347","author":"Shi","year":"2024","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2025.119240_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijheh.2024.114408","article-title":"Prenatal and childhood exposure to bisphenols and bone mineral density in 7-year-old children from the odense child cohort","volume":"260","author":"Sigvaldsen","year":"2024","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"10.1016\/j.ecoenv.2025.119240_bib42","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/j.1439-0426.2010.01409.x","article-title":"Zebrafish as a unique model system in bone research: the power of genetics andin vivoimaging","volume":"26","author":"Spoorendonk","year":"2010","journal-title":"J. Appl. Ichthyol."},{"key":"10.1016\/j.ecoenv.2025.119240_bib43","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1289\/ehp.1409427","article-title":"Bisphenol A, bisphenol S, and 4-Hydroxyphenyl 4-Isoprooxyphenylsulfone (BPSIP) in urine and blood of cashiers","volume":"124","author":"Thayer","year":"2016","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ecoenv.2025.119240_bib44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.lfs.2018.02.013","article-title":"Bisphenol a exposure disturbs the bone metabolism: an evolving interest towards an old culprit","volume":"198","author":"Thent","year":"2018","journal-title":"Life Sci."},{"key":"10.1016\/j.ecoenv.2025.119240_bib45","doi-asserted-by":"crossref","first-page":"R50","DOI":"10.1093\/hmg\/ddv228","article-title":"New insights into craniofacial malformations","volume":"24","author":"Twigg","year":"2015","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ecoenv.2025.119240_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2024.114772","article-title":"Exposure to BPA and BPS during pregnancy disrupts the bone mineralization in the offspring","volume":"189","author":"Varma","year":"2024","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.ecoenv.2025.119240_bib47","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s00216-010-3464-7","article-title":"Comparison of two derivatization-based methods for solid-phase microextraction\u2013gas chromatography\u2013mass spectrometric determination of bisphenol A, bisphenol s and biphenol migrated from food cans","volume":"397","author":"Vi\u00f1as","year":"2010","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.ecoenv.2025.119240_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2022.115042","article-title":"Involvement of NLRP3\/Caspase-1\/GSDMD-Dependent pyroptosis in BPA-Induced apoptosis of human neuroblastoma cells","volume":"200","author":"Wang","year":"2022","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ecoenv.2025.119240_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2021.152830","article-title":"Bisphenol a exposure prenatally delays bone development and bone mass accumulation in female rat offspring via the ER\u03b2\/HDAC5\/TGF\u03b2 signaling pathway","volume":"458","author":"Wang","year":"2021","journal-title":"Toxicology"},{"key":"10.1016\/j.ecoenv.2025.119240_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2020.105546","article-title":"Antagonistic effects of multi-walled carbon nanotubes and BDE-47 in zebrafish (Danio rerio): oxidative stress, apoptosis and DNA damage","volume":"225","author":"Wang","year":"2020","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.ecoenv.2025.119240_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2025.109442","article-title":"PPAR\u03b3-SMAD6 axis-mediated inhibition of osteogenic differentiation is involved in BPS-induced osteoporosis","volume":"198","author":"Weng","year":"2025","journal-title":"Environ. Int."},{"key":"10.1016\/j.ecoenv.2025.119240_bib52","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.scitotenv.2017.09.194","article-title":"Occurrence of bisphenol s in the environment and implications for human exposure: a short review","volume":"615","author":"Wu","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2025.119240_bib53","doi-asserted-by":"crossref","DOI":"10.1093\/conphys\/coaa138","article-title":"Bisphenols alter thermal responses and performance in zebrafish (Danio rerio)","volume":"9","author":"Wu","year":"2021","journal-title":"Conserv. Physiol."},{"key":"10.1016\/j.ecoenv.2025.119240_bib54","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1038\/onc.2013.90","article-title":"ACP5, a direct transcriptional target of FoxM1, promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma","volume":"33","author":"Xia","year":"2013","journal-title":"Oncogene"},{"key":"10.1016\/j.ecoenv.2025.119240_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.122549","article-title":"Mechanism investigation on bisphenol S-induced oxidative stress and inflammation in murine RAW264.7 cells: the role of NLRP3 inflammasome, TLR4, Nrf2 and MAPK","volume":"394","author":"Xie","year":"2020","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2025.119240_bib56","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s12011-017-1176-y","article-title":"Fas- and mitochondria-mediated signaling pathway involved in osteoblast apoptosis induced by AlCl3","volume":"184","author":"Xu","year":"2017","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.ecoenv.2025.119240_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.122697","article-title":"Head dysgenesis and disruption of cranial neural crest stem cells behaviour by 4-octylphenol in fire-bellied toad bombina orientalis embryos","volume":"338","author":"Xu","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2025.119240_bib58","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.chemosphere.2014.05.004","article-title":"Urinary levels of bisphenol analogues in residents living near a manufacturing plant in south China","volume":"112","author":"Yang","year":"2014","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2025.119240_bib59","article-title":"Ganoderma lucidum immune modulator protein rLZ-8 could prevent and reverse bone loss in Glucocorticoids-Induced osteoporosis rat model","volume":"11","author":"Yang","year":"2020","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.ecoenv.2025.119240_bib60","article-title":"Bisphenol a exacerbates selenium deficiency-induced pyroptosis via the NF-\u03baB\/NLRP3\/Caspase-1 pathway in chicken trachea","volume":"263","author":"Yin","year":"2023","journal-title":"Compar. Biochem. Physiol. Part C Toxicol. Pharmacol."},{"key":"10.1016\/j.ecoenv.2025.119240_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.133332","article-title":"Exposure of Male adult zebrafish (Danio rerio) to triphenyl phosphate (TPhP) induces eye development disorders and disrupts neurotransmitter system-mediated abnormal locomotor behavior in larval offspring","volume":"465","author":"Zhang","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2025.119240_bib62","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.113119","article-title":"Bisphenol a induces apoptosis and autophagy in murine osteocytes MLO-Y4: involvement of ROS-mediated mTOR\/ULK1 pathway","volume":"230","author":"Zhang","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2025.119240_bib63","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2021.112772","article-title":"Bisphenol a induces pyroptotic cell death via ROS\/NLRP3\/Caspase-1 pathway in osteocytes MLO-Y4","volume":"159","author":"Zhang","year":"2022","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.ecoenv.2025.119240_bib64","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.scitotenv.2017.03.035","article-title":"Bisphenol s exposure modulate macrophage phenotype as defined by cytokines profiling, global metabolomics and lipidomics analysis","volume":"592","author":"Zhao","year":"2017","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2025.119240_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.116395","article-title":"Exposure to acrylamide induces skeletal developmental toxicity in zebrafish and rat embryos","volume":"271","author":"Zhu","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2025.119240_bib66","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22010053","article-title":"Bisphosphonates reduce Smoking-Induced Osteoporotic-Like alterations by regulating RANKL\/OPG in an osteoblast and osteoclast Co-Culture model","volume":"22","author":"Zhu","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ecoenv.2025.119240_bib67","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.114082","article-title":"Long-term BPA exposure leads to bone malformation and abnormal expression of MAPK\/Wnt\/FoxO signaling pathway genes in zebrafish offspring","volume":"245","author":"Zhu","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2025.119240_bib68","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2020.109602","article-title":"Fetal exposure to bisphenols and phthalates and childhood bone mass: a population-based prospective cohort study","volume":"186","author":"van Zwol-Janssens","year":"2020","journal-title":"Environ. Res."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651325015854?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651325015854?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T11:35:39Z","timestamp":1773833739000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651325015854"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":68,"alternative-id":["S0147651325015854"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2025.119240","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bisphenol S as an emerging osteotoxicant: Mechanistic insights from osteoblasts and zebrafish models","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2025.119240","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"119240"}}