{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T03:13:46Z","timestamp":1777778026663,"version":"3.51.4"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T00:00:00Z","timestamp":1771545600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002701","name":"Ministry of Education","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.ecoenv.2026.119926","type":"journal-article","created":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T11:01:20Z","timestamp":1772190080000},"page":"119926","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["KABP\u2013AB-cx13 for the alleviation of airway inflammation in a mouse model triggered by particulate matter 10(PM10) and diesel exhaust particles"],"prefix":"10.1016","volume":"312","author":[{"given":"Ji Hye","family":"Oh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won-Kyung","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chae-Eun","family":"Shin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji-Hyun","family":"Yun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gyu Min","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang Won","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seock-Yeon","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4598-1733","authenticated-orcid":false,"given":"Seung-Hyung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2026.119926_bib1","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.aninu.2021.11.005","article-title":"Gut microbiota-derived short chain fatty acids are potential mediators in gut inflammation","volume":"8","author":"Akhtar","year":"2022","journal-title":"Anim. Nutr."},{"key":"10.1016\/j.ecoenv.2026.119926_bib2","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1007\/s00431-025-06587-7","article-title":"A probiotic containing L. plantarum and P. acidilactici strains for treating upper respiratory infection in children aged 6 months to 5 years: a randomized, double-blind trial","volume":"184","author":"Andrade-Platas","year":"2025","journal-title":"Eur. J. Pediatr."},{"key":"10.1016\/j.ecoenv.2026.119926_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2024.123686","article-title":"PM2.5 induces a senescent state in mouse AT2 cells","volume":"347","author":"Cheng","year":"2024","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2026.119926_bib4","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1038\/s41385-019-0160-6","article-title":"Microbes, metabolites, and the gut-lung axis","volume":"12","author":"Dang","year":"2019","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.ecoenv.2026.119926_bib5","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3389\/fcimb.2020.00009","article-title":"The gut-lung axis in health and respiratory diseases: a place for inter-organ and inter-kingdom crosstalks","volume":"10","author":"Enaud","year":"2020","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.ecoenv.2026.119926_bib6","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1007\/s13340-016-0290-y","article-title":"M2 macrophages in metabolism","volume":"7","author":"Fujisaka","year":"2016","journal-title":"Diabetol. Int."},{"key":"10.1016\/j.ecoenv.2026.119926_bib7","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.freeradbiomed.2020.01.179","article-title":"Air pollution and its effects on the immune system","volume":"151","author":"Glencross","year":"2020","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.ecoenv.2026.119926_bib8","doi-asserted-by":"crossref","DOI":"10.1096\/fasebj.2022.36.S1.R2343","article-title":"Probiotic effect on SARS-CoV2 immunity is associated to Type-1 interferons: a post-hoc analysis of a randomized, placebo-controlled trial","volume":"36","author":"Guti\u00e9rrez-Castrell\u00f3n","year":"2022","journal-title":"FASEB J."},{"key":"10.1016\/j.ecoenv.2026.119926_bib9","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2021.2018899","article-title":"Probiotic improves symptomatic and viral clearance in Covid19 outpatients: a randomized, quadruple-blinded, placebo-controlled trial","volume":"14","author":"Guti\u00e9rrez-Castrell\u00f3n","year":"2022","journal-title":"Gut Microbes"},{"key":"10.1016\/j.ecoenv.2026.119926_bib10","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1152\/physrev.00056.2024","article-title":"Immunological and regenerative properties of lung stem cells","volume":"106","author":"Hao","year":"2026","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.ecoenv.2026.119926_bib11","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/s41423-021-00832-3","article-title":"Neutrophils in chronic inflammatory diseases","volume":"19","author":"Herrero-Cervera","year":"2022","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.ecoenv.2026.119926_bib12","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/619523","article-title":"Contribution of lung macrophages to the inflammatory responses induced by exposure to air pollutants","volume":"2013","author":"Hiraiwa","year":"2013","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.ecoenv.2026.119926_bib13","unstructured":"Institute for Health Metrics and Evaluation, State of global air 2024, Special report. \u3008https:\/\/www.healtheffects.org\/announcements\/new-state-global-air-report-finds-air-pollution-second-leading-risk-factor-death\u3009, 2024."},{"key":"10.1016\/j.ecoenv.2026.119926_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.119066","article-title":"Probiotics, prebiotics, and Synbiotics to prevent or combat air pollution consequences: the gut-lung axis","volume":"302","author":"Keulers","year":"2022","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2026.119926_bib15","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.envint.2014.10.005","article-title":"A review on the human health impact of airborne particulate matter","volume":"74","author":"Kim","year":"2015","journal-title":"Environ. Int."},{"key":"10.1016\/j.ecoenv.2026.119926_bib16","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/j.immuni.2016.11.010","article-title":"Inhaled fine particles induce alveolar macrophage death and interleukin-1\u03b1 release to promote inducible bronchus-associated lymphoid tissue formation","volume":"45","author":"Kuroda","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/j.ecoenv.2026.119926_bib17","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.4049\/jimmunol.162.4.2347","article-title":"A. Lind\u00e9n, Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways","volume":"162","author":"Laan","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.ecoenv.2026.119926_bib18","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2023.1145546","article-title":"Lactobacillus paracasei ATG-E1 improves particulate matter 10 plus diesel exhaust particles (PM10D)-induced airway inflammation by regulating immune responses","volume":"14","author":"Lee","year":"2023","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.ecoenv.2026.119926_bib19","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/s12276-020-0394-0","article-title":"Mechanisms of ultrafine particle-induced respiratory health effects","volume":"52","author":"Leikauf","year":"2020","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.ecoenv.2026.119926_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2025.114979","article-title":"1-O-Acetylbritannilactone exerts anti-inflammatory and anti-MUC5AC effects by targeting PKC-\u03b1 and downregulating the SRC\/EGFR\/MAPK signaling pathway","volume":"161","author":"Li","year":"2025","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.ecoenv.2026.119926_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2020.104286","article-title":"Lactobacillus reuteri CCFM1072 and CCFM1040 with the role of Treg cells regulation alleviate airway inflammation through modulating gut microbiota in allergic asthma mice","volume":"76","author":"Li","year":"2021","journal-title":"J. Funct. Foods"},{"key":"10.1016\/j.ecoenv.2026.119926_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.132227","article-title":"Short-term PM2.5 exposure induces transient lung injury and repair","volume":"459","author":"Li","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2026.119926_bib23","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.envint.2015.02.010","article-title":"Analysing the health effects of simultaneous exposure to physical and chemical properties of airborne particles","volume":"79","author":"Pirani","year":"2015","journal-title":"Environ. Int."},{"key":"10.1016\/j.ecoenv.2026.119926_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2019.101239","article-title":"Programmed necrotic cell death of macrophages: focus on pyroptosis, necroptosis, and parthanatos","volume":"26","author":"Robinson","year":"2019","journal-title":"Redox Biol."},{"key":"10.1016\/j.ecoenv.2026.119926_bib25","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1038\/s41575-019-0173-3","article-title":"Probiotics and prebiotics in intestinal health and disease: from biology to the clinic","volume":"16","author":"Sanders","year":"2019","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.ecoenv.2026.119926_bib26","doi-asserted-by":"crossref","first-page":"399","DOI":"10.2147\/COPD.S144312","article-title":"Management of airway mucus hypersecretion in chronic airway inflammatory disease: Chinese expert consensus, English ed. The pharmacological research progress of Siraitia grosvenorii","volume":"13","author":"Shen","year":"2018","journal-title":"Int. J. Chron. Obs. Pulmon. Dis."},{"key":"10.1016\/j.ecoenv.2026.119926_bib27","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1097\/JOM.0000000000001277","article-title":"Airborne particulate matter: human exposure and health effects","volume":"60","author":"Thompson","year":"2018","journal-title":"J. Occup. Environ. Med."},{"key":"10.1016\/j.ecoenv.2026.119926_bib28","unstructured":"U.S Energy Information Administration Office (EIA), Annual Energy Outlook 2020 with Projections to 2050. \u3008www.eia.gov\/aeo\u3009, (accessed 29 January 2020)."},{"key":"10.1016\/j.ecoenv.2026.119926_bib29","doi-asserted-by":"crossref","first-page":"7581","DOI":"10.1038\/s41598-022-11553-6","article-title":"Particulate matter (PM10) induces in vitro activation of human neutrophils, and lung histopathological alterations in a mouse model","volume":"12","author":"Valderrama","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ecoenv.2026.119926_bib30","author":"World Health Organization","year":"2025","journal-title":"WHO Supports renewed Ctry. Commit. Action air Qual."},{"key":"10.1016\/j.ecoenv.2026.119926_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.114060","article-title":"Probiotics ameliorates pulmonary inflammation via modulating gut microbiota and rectifying Th17\/Treg imbalance in a rat model of PM2.5 induced lung injury","volume":"244","author":"Wu","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2026.119926_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2025.109525","article-title":"Air pollutants and lung regeneration: impact on the fate of lung stem cells","volume":"199","author":"Wu","year":"2025","journal-title":"Environ. Int."},{"key":"10.1016\/j.ecoenv.2026.119926_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.142502","article-title":"Rapid and green combustion synthesis of dysprosium cerium oxide nanostructures: incorporation into wheat starch\/sage seed gum hybrid composites","volume":"308","author":"Yousefi","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ecoenv.2026.119926_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.jenvman.2023.119545","article-title":"Novel rod-like [Cu(phen)\u2082(OAc)]\u00b7PF\u2086 complex for high-performance visible-light-driven photocatalytic degradation of hazardous organic dyes: DFT approach, Hirshfeld and fingerprint plot analysis","volume":"350","author":"Zinatloo-Ajabshir","year":"2024","journal-title":"J. Environ. Manag."},{"key":"10.1016\/j.ecoenv.2026.119926_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.measurement.2024.114924","article-title":"A green route for the synthesis of sponge-like Pr\u2086O\u2081\u2081 nanoparticles and their application for the development of chlorambucil sensor","volume":"235","author":"Zinatloo-Ajabshir","year":"2024","journal-title":"Measurement"}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651326002551?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651326002551?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:17:35Z","timestamp":1777490255000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651326002551"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":35,"alternative-id":["S0147651326002551"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2026.119926","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"KABP\u2013AB-cx13 for the alleviation of airway inflammation in a mouse model triggered by particulate matter 10(PM10) and diesel exhaust particles","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2026.119926","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"119926"}}