{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T17:29:01Z","timestamp":1793554141763,"version":"4.5.0"},"reference-count":67,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T00:00:00Z","timestamp":1786406400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["2125727"],"award-info":[{"award-number":["2125727"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["1944157"],"award-info":[{"award-number":["1944157"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.ecoenv.2026.120662","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T16:30:47Z","timestamp":1786638647000},"page":"120662","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Physiological and molecular effects of individual and mixtures of drugs of abuse in Crassostrea virginica larvae"],"prefix":"10.1016","volume":"323","author":[{"given":"Gustavo","family":"Salcedo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric J.J.","family":"Chain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4090-957X","authenticated-orcid":false,"given":"Sheree A.","family":"Pagsuyoin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"15","key":"10.1016\/j.ecoenv.2026.120662_bib1","doi-asserted-by":"crossref","first-page":"5708","DOI":"10.1016\/j.watres.2013.06.057","article-title":"Stereoselective biodegradation of amphetamine and methamphetamine in river microcosms","volume":"47","author":"Bagnall","year":"2013","journal-title":"Water Res."},{"key":"10.1016\/j.ecoenv.2026.120662_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.118201","article-title":"Phytocannabinoids in neuromodulation: From omics to epigenetics","volume":"330","author":"Banerjee","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.ecoenv.2026.120662_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.143589","article-title":"Water quality criteria for selected pharmaceuticals and personal care products for the protection of marine ecosystems","volume":"758","author":"Beiras","year":"2021","journal-title":"Sci. Total. Environ."},{"key":"10.1016\/j.ecoenv.2026.120662_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2024.123355","article-title":"Daphnia magna: an emerging environmental model of neuro- and cardiotoxicity of illicit drugs","volume":"344","author":"Bellot","year":"2024","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2026.120662_bib5","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.neuro.2023.01.003","article-title":"Toxicity and behavioural effects of ocfentanil and 2-furanylfentanyl in zebrafish larvae and mice","volume":"95","author":"Bilel","year":"2023","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.ecoenv.2026.120662_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.marenvres.2022.105677","article-title":"Metal contamination and heat stress impair swimming behavior and acetylcholinesterase activity in embryo-larval stages of the Mediterranean mussel, Mytilus galloprovincialis","volume":"179","author":"Boukadida","year":"2022","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.ecoenv.2026.120662_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.113978","article-title":"High-density polyethylene (HDPE) microplastics impair development and swimming activity of Pacific oyster D-larvae, Crassostrea gigas, depending on particle size","volume":"260","author":"Bringer","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2026.120662_bib8","article-title":"Zebrafish (Danio rerio) larvae show behavioral and embryonic development defects when exposed to opioids at embryo stage","volume":"85","author":"Cadena","year":"2021","journal-title":"Neurotoxicol. Teratol."},{"issue":"1","key":"10.1016\/j.ecoenv.2026.120662_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0044-8486(84)90384-3","article-title":"Rearing system for feeding fish larvae on dry diets. Trial with carp (Cyprinus carpio L.) larvae","volume":"41","author":"Charlon","year":"1984","journal-title":"Aquaculture"},{"issue":"4","key":"10.1016\/j.ecoenv.2026.120662_bib10","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.3390\/ijms22042103","article-title":"The endocannabinoid system and invertebrate neurodevelopment and regeneration","volume":"22","author":"Clarke","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ecoenv.2026.120662_bib11","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.chemosphere.2018.01.158","article-title":"Occurrence of illicit drugs in two wastewater treatment plants in the south of Italy","volume":"198","author":"Cosenza","year":"2018","journal-title":"Chemosphere"},{"issue":"2","key":"10.1016\/j.ecoenv.2026.120662_bib12","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.2517-6161.1972.tb00899.x","article-title":"Regression models and life-tables","volume":"34","author":"Cox","year":"1972","journal-title":"J. R. Stat. Soc. Ser. B (Methodol."},{"key":"10.1016\/j.ecoenv.2026.120662_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.174798","article-title":"Cocaine shark\u201d: first report on cocaine and benzoylecgonine detection in sharks","volume":"948","author":"de Farias Araujo","year":"2024","journal-title":"Sci. Total. Environ."},{"key":"10.1016\/j.ecoenv.2026.120662_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.137728","article-title":"Methamphetamine exposure modulated oxidative status and altered the reproductive output in Daphnia magna","volume":"721","author":"De Felice","year":"2020","journal-title":"Sci. Total. Environ."},{"issue":"1","key":"10.1016\/j.ecoenv.2026.120662_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12302-020-00304-x","article-title":"Occurrence and removal of illicit drugs in different wastewater treatment plants with different treatment techniques","volume":"32","author":"Deng","year":"2020","journal-title":"Environ. Sci. Eur."},{"issue":"4","key":"10.1016\/j.ecoenv.2026.120662_bib16","doi-asserted-by":"crossref","first-page":"537","DOI":"10.3390\/ph17040537","article-title":"Illicit drugs in surface waters: how to get fish off the addictive hook","volume":"17","author":"Falfushynska","year":"2024","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.ecoenv.2026.120662_bib17","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.chemosphere.2019.02.041","article-title":"Psychoactive pharmaceuticals and illicit drugs in coastal waters of north-western Spain: environmental exposure and risk assessment","volume":"224","author":"Fern\u00e1ndez-Rubio","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2026.120662_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2021.105873","article-title":"Effects of opioids on reproduction in Japanese medaka (Oryzias latipes)","volume":"236","author":"Fischer","year":"2021","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.ecoenv.2026.120662_bib19","unstructured":"Food and Agriculture Organization of the United Nations. (2026). Crassostrea virginica. Fisheries and Aquaculture Division. Retrieved March 1, 2026, from https:\/\/www.fao.org\/fishery\/en\/culturedspecies\/crassostrea_virginica\/en."},{"issue":"4","key":"10.1016\/j.ecoenv.2026.120662_bib20","doi-asserted-by":"crossref","first-page":"3675","DOI":"10.1007\/s11356-019-04156-8","article-title":"Assessment of swimming behavior of the Pacific oyster D-larvae (Crassostrea gigas) following exposure to model pollutants","volume":"27","author":"Gamain","year":"2020","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.ecoenv.2026.120662_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.yrtph.2023.105437","article-title":"Improving the regulatory environmental risk assessment of human pharmaceuticals: required changes in the new legislation","volume":"142","author":"Gildemeister","year":"2023","journal-title":"Regul. Toxicol. Pharmacol."},{"issue":"4","key":"10.1016\/j.ecoenv.2026.120662_bib22","doi-asserted-by":"crossref","first-page":"274","DOI":"10.4103\/0974-7788.76794","article-title":"Understanding survival analysis: Kaplan\u2013Meier estimate","volume":"1","author":"Goel","year":"2010","journal-title":"Int. J. Ayurveda Res."},{"key":"10.1016\/j.ecoenv.2026.120662_bib23","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.aquaculture.2013.03.031","article-title":"Chemical induction of settlement behavior in larvae of the eastern oyster Crassostrea virginica (Gmelin)","volume":"402","author":"Grant","year":"2013","journal-title":"Aquaculture"},{"key":"10.1016\/j.ecoenv.2026.120662_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.jenvman.2020.111479","article-title":"Prioritizing pharmaceuticals based on environmental risks in the aquatic environment in China","volume":"278","author":"Guo","year":"2021","journal-title":"J. Environ. Manag."},{"issue":"6","key":"10.1016\/j.ecoenv.2026.120662_bib25","doi-asserted-by":"crossref","first-page":"3100","DOI":"10.1021\/es4047507","article-title":"Principles of sound ecotoxicology","volume":"48","author":"Harris","year":"2014","journal-title":"Environ. Sci. & Technol."},{"key":"10.1016\/j.ecoenv.2026.120662_bib26","doi-asserted-by":"crossref","first-page":"252","DOI":"10.2307\/1351527","article-title":"Swimming speeds of oyster larvae Crassostrea virginica in different salinities and temperatures","volume":"1","author":"Hidu","year":"1978","journal-title":"Estuaries"},{"key":"10.1016\/j.ecoenv.2026.120662_bib27","first-page":"1","article-title":"The assessment of marine pollution-bioassays with bivalve embryos and larvae","volume":"37","author":"His","year":"1999"},{"key":"10.1016\/j.ecoenv.2026.120662_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.115642","article-title":"A critical review on the detection, occurrence, fate, toxicity, and removal of cannabinoids in the water system and the environment","volume":"268","author":"How","year":"2021","journal-title":"Environ. Pollut."},{"issue":"2","key":"10.1016\/j.ecoenv.2026.120662_bib29","doi-asserted-by":"crossref","first-page":"395","DOI":"10.3390\/hydrobiology2020026","article-title":"Pharmaceuticals in water: risks to aquatic life and remediation strategies","volume":"2","author":"Khan","year":"2023","journal-title":"Hydrobiology"},{"issue":"5","key":"10.1016\/j.ecoenv.2026.120662_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.jece.2021.105874","article-title":"Hospital effluent guidelines and legislation scenario around the globe: a critical review","volume":"9","author":"Khan","year":"2021","journal-title":"J. Environ. Chem. Eng."},{"key":"10.1016\/j.ecoenv.2026.120662_bib31","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.scitotenv.2019.03.372","article-title":"Comparison of regulatory frameworks of environmental risk assessments for human pharmaceuticals in EU, USA, and Canada","volume":"671","author":"Lee","year":"2019","journal-title":"Sci. Total. Environ."},{"key":"10.1016\/j.ecoenv.2026.120662_bib32","series-title":"Short-Term Methods for Estimating the Chronic Toxicity of Effluents and Receiving Waters to Freshwater Organisms","year":"1994"},{"key":"10.1016\/j.ecoenv.2026.120662_bib33","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1016\/j.marpolbul.2019.07.042","article-title":"Psychoactive substances in mussels: Analysis and occurrence assessment","volume":"146","author":"L\u00f3pez-Garc\u00eda","year":"2019","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.ecoenv.2026.120662_bib34","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.psep.2023.02.031","article-title":"Toxic interactions between microplastics and the antifungal agent ketoconazole in sediments on Limnodrilus hoffmeistteri","volume":"172","author":"Lu","year":"2023","journal-title":"Process Saf. Environ. Prot."},{"key":"10.1016\/j.ecoenv.2026.120662_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.162806","article-title":"Long-term wastewater-based surveillance and impacts of the COVID-19 pandemic on drug use trends in a U.S. northeast rural town","volume":"877","author":"Luo","year":"2023","journal-title":"Sci. Total. Environ."},{"key":"10.1016\/j.ecoenv.2026.120662_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.155780","article-title":"Health effects and risks associated with the occurrence of pharmaceuticals and their metabolites in marine organisms and seafood","volume":"837","author":"Madikizela","year":"2022","journal-title":"Sci. Total. Environ."},{"key":"10.1016\/j.ecoenv.2026.120662_bib37","doi-asserted-by":"crossref","first-page":"8845","DOI":"10.1021\/acs.est.2c09576","article-title":"\"Factors determining the susceptibility of fish to effects of human pharmaceuticals.\"","volume":"24","author":"Matthee","year":"2023","journal-title":"Environ. Sci. & Technol. 57"},{"key":"10.1016\/j.ecoenv.2026.120662_bib38","first-page":"183","article-title":"Methods for cell and particle tracking","volume":"504","author":"Meijering","year":"2012"},{"key":"10.1016\/j.ecoenv.2026.120662_bib39","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1146\/annurev-marine-040821-075606","article-title":"The biological effects of pharmaceuticals in the marine environment","volume":"14","author":"Mezzelani","year":"2022","journal-title":"Annu. Rev. Mar. Sci."},{"key":"10.1016\/j.ecoenv.2026.120662_bib40","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.envint.2019.04.038","article-title":"Biomonitoring of pesticides, pharmaceuticals and illicit drugs in a freshwater invertebrate to estimate toxic or effect pressure","volume":"129","author":"Miller","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.ecoenv.2026.120662_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2018.11.022","article-title":"Extra-mitochondrial Cu\/Zn superoxide dismutase (Sod1) is dispensable for protection against oxidative stress but mediates peroxide signaling in Saccharomyces cerevisiae","volume":"21","author":"Montllor-Albalate","year":"2019","journal-title":"Redox Biol."},{"key":"10.1016\/j.ecoenv.2026.120662_bib42","article-title":"Application of design of experiment for quantification of 71 new psychoactive substances in influent wastewater","volume":"1289","author":"Nadarajan","year":"2024","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.ecoenv.2026.120662_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpc.2020.108917","article-title":"Glutathione-S-transferase alpha-4 in Hippocampus abdominalis (big-belly seahorse): Molecular characterization, antioxidant properties, and its potent immune response","volume":"240","author":"Nadarajapillai","year":"2021","journal-title":"Comparative Biochemistry Physiology Part C Toxicology & Pharmacology"},{"key":"10.1016\/j.ecoenv.2026.120662_bib44","unstructured":"National Institutes of Health, 2020. Methamphetamine-involved overdose deaths nearly tripled between 2015 and 2019, NIH study finds. Retrieved 31 January 2026 from https:\/\/www.nih.gov\/news-events\/news-releases\/methamphetamine-involved-overdose-deaths-nearly-tripled-between-2015-2019-nih-study-finds."},{"issue":"24","key":"10.1016\/j.ecoenv.2026.120662_bib45","doi-asserted-by":"crossref","first-page":"25835","DOI":"10.1021\/acsomega.4c02486","article-title":"Stability and degradation of opioids in river water","volume":"9","author":"Niroula","year":"2024","journal-title":"ACS Omega"},{"key":"10.1016\/j.ecoenv.2026.120662_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2025.180314","article-title":"Global occurrence and distribution of drugs of abuse in rivers: a comprehensive systematic review","volume":"1000","author":"Niroula","year":"2025","journal-title":"Sci. Total. Environ."},{"issue":"10","key":"10.1016\/j.ecoenv.2026.120662_bib47","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/j.chemosphere.2012.02.004","article-title":"Predicting EDC concentrations in a river mixing zone","volume":"87","author":"Pagsuyoin","year":"2012","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2026.120662_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.127666","article-title":"Effects of sewer biofilm on the degradation of drugs in sewage: a microcosm study","volume":"424","author":"Pagsuyoin","year":"2022","journal-title":"J. Hazard. Mater."},{"issue":"2","key":"10.1016\/j.ecoenv.2026.120662_bib49","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1002\/etc.3575","article-title":"Increase in cannabis use may indirectly affect the health status of a freshwater species","volume":"36","author":"Parolini","year":"2017","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.ecoenv.2026.120662_bib50","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.envpol.2017.09.038","article-title":"Benzoylecgonine exposure induced oxidative stress and altered swimming behavior and reproduction in Daphnia magna","volume":"232","author":"Parolini","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2026.120662_bib51","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.scitotenv.2016.01.051","article-title":"Occurrence of pharmaceuticals and cocaine in a Brazilian coastal zone","volume":"548\u2013549","author":"Pereira","year":"2016","journal-title":"Sci. Total. Environ."},{"issue":"11","key":"10.1016\/j.ecoenv.2026.120662_bib52","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.3390\/life13112180","article-title":"The therapeutic potential of amphetamine-like psychostimulants","volume":"13","author":"Pires","year":"2023","journal-title":"Life"},{"issue":"3","key":"10.1016\/j.ecoenv.2026.120662_bib53","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.otohns.2010.05.007","article-title":"A practical guide to understanding Kaplan\u2013Meier curves","volume":"143","author":"Rich","year":"2010","journal-title":"Otolaryngol. Head. Neck Surg."},{"issue":"6","key":"10.1016\/j.ecoenv.2026.120662_bib54","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.ntt.2011.05.011","article-title":"Behavioral and physiological effects of acute ketamine exposure in adult zebrafish","volume":"33","author":"Riehl","year":"2011","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.ecoenv.2026.120662_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.marpolbul.2025.117985","article-title":"Adverse impacts of drugs of abuse on the survival, growth, and mobility of Crassostrea virginica oyster larvae","volume":"216","author":"Salcedo","year":"2025","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.ecoenv.2026.120662_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2025.118589","article-title":"Changes in survival, swimming behavior, and stress biomarker expression in Crassostrea virginica larvae in response to exposure to drugs of abuse","volume":"302","author":"Salcedo","year":"2025","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2026.120662_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.111999","article-title":"Traces of tramadol in water impact behaviour in a native European fish","volume":"212","author":"Santos","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2026.120662_bib58","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1016\/j.scitotenv.2018.03.060","article-title":"Contamination profiles, mass loadings, and sewage epidemiology of neuropsychiatric and illicit drugs in wastewater and river waters from a community in the Midwestern United States","volume":"631\u2013632","author":"Skees","year":"2018","journal-title":"Sci. Total. Environ."},{"key":"10.1016\/j.ecoenv.2026.120662_bib59","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.gene.2018.10.033","article-title":"Identification of MAPK gene family in Lateolabrax maculatus and their expression profiles in response to hypoxia and salinity challenges","volume":"684","author":"Tian","year":"2019","journal-title":"Gene"},{"key":"10.1016\/j.ecoenv.2026.120662_bib60","unstructured":"United Nations Office on Drugs and Crime2024. World drug report 2024. United Nations. https:\/\/www.unodc.org\/unodc\/en\/data-and-analysis\/world-drug-report-2024.html."},{"key":"10.1016\/j.ecoenv.2026.120662_bib61","series-title":"A practical manual for remote setting in Virginia","author":"Virginia Marine Resources Commission","year":"2024"},{"issue":"1","key":"10.1016\/j.ecoenv.2026.120662_bib62","doi-asserted-by":"crossref","DOI":"10.1242\/jeb.149583","article-title":"Biomechanics of swimming in developing larval fish","volume":"221","author":"Voesenek","year":"2018","journal-title":"J. Exp. Biol."},{"issue":"1","key":"10.1016\/j.ecoenv.2026.120662_bib63","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1039\/C4EM00394B","article-title":"Emerging pollutants in the Esmeraldas watershed in Ecuador: Discharge and attenuation of emerging organic pollutants along the San Pedro\u2013Guayllabamba\u2013Esmeraldas rivers","volume":"17","author":"Voloshenko-Rossin","year":"2015","journal-title":"Environmental Science Processes & Impacts"},{"key":"10.1016\/j.ecoenv.2026.120662_bib64","series-title":"Oyster Hatchery Techniques","author":"Wallace","year":"2008"},{"issue":"1","key":"10.1016\/j.ecoenv.2026.120662_bib65","doi-asserted-by":"crossref","first-page":"64","DOI":"10.3390\/toxics12010064","article-title":"The exploration of joint toxicity and associated mechanisms of primary microplastics and methamphetamine in zebrafish larvae","volume":"12","author":"Wang","year":"2024","journal-title":"Toxics"},{"key":"10.1016\/j.ecoenv.2026.120662_bib66","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s11270-020-04565-3","article-title":"Occurrence of stimulant drugs of abuse in a San Diego, CA, stream and their consumption rates in the neighboring community","volume":"231","author":"Watanabe","year":"2020","journal-title":"Water Air & Soil. Pollut."},{"key":"10.1016\/j.ecoenv.2026.120662_bib67","doi-asserted-by":"crossref","DOI":"10.1016\/j.marenvres.2024.106470","article-title":"Occurrence and distribution of antibiotics and antibiotic resistance genes from the land to ocean in Daliao River-Liaodong Bay, China","volume":"197","author":"Xu","year":"2024","journal-title":"Mar. Environ. Res."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651326009929?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651326009929?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T17:12:57Z","timestamp":1793553177000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651326009929"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":67,"alternative-id":["S0147651326009929"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2026.120662","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Physiological and molecular effects of individual and mixtures of drugs of abuse in Crassostrea virginica larvae","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2026.120662","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"120662"}}