{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T18:27:21Z","timestamp":1793557641072,"version":"4.5.0"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005046","name":"Natural Science Foundation of Heilongjiang Province","doi-asserted-by":"publisher","award":["YQ2023C002"],"award-info":[{"award-number":["YQ2023C002"]}],"id":[{"id":"10.13039\/501100005046","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42530716"],"award-info":[{"award-number":["42530716"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.ecoenv.2026.120665","type":"journal-article","created":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T12:49:28Z","timestamp":1786798168000},"page":"120665","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Biological and metabolism responses of earthworm (Eisenia fetida) exposed to metribuzin"],"prefix":"10.1016","volume":"323","author":[{"given":"Bo","family":"Cao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinye","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongjia","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinran","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Houcen","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiqi","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duo","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8299-3848","authenticated-orcid":false,"given":"Ying","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2026.120665_bib1","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.pestbp.2012.04.013","article-title":"The effects of metribuzin on early life stages of common carp (Cyprinus carpio)","volume":"103","author":"\u0160t\u011bp\u00e1nov\u00e1","year":"2012","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.ecoenv.2026.120665_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2019.113032","article-title":"Exposure to nickel oxide nanoparticles insinuates physiological, ultrastructural and oxidative damage: A life cycle study on Eisenia fetida","volume":"254","author":"Adeel","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2026.120665_bib3","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.aquatox.2019.02.021","article-title":"Oxidative stress potential of the herbicides bifenox and metribuzin in the microalgae Chlamydomonas reinhardtii","volume":"210","author":"Almeida","year":"2019","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.ecoenv.2026.120665_bib4","article-title":"Effect of the Ni3TeO6 phase in a Ni2Te3O8\/expanded graphite composite on the electrochemical monitoring of metribuzin residue in soil and water samples","volume":"435","author":"Annamalai","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2026.120665_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.pestbp.2022.105320","article-title":"NMR-based metabolomics approach to assess the ecotoxicity of prothioconazole on the earthworm (Eisenia fetida) in soil","volume":"190","author":"Bao","year":"2023","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.ecoenv.2026.120665_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.127578","article-title":"Interactive effects of environmental microplastics and 2,4-dichlorophenoxyacetic acid (2,4-D) on the earthworm Eisenia andrei","volume":"424","author":"Boughattas","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2026.120665_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.123213","article-title":"Co-exposure to environmental microplastic and the pesticide 2,4-dichlorophenoxyacetic acid (2,4-D) induce distinctive alterations in the metabolome and microbial community structure in the gut of the earthworm Eisenia andrei","volume":"344","author":"Boughattas","year":"2024","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2026.120665_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.apsoil.2022.104583","article-title":"Combined toxicity of acetochlor and metribuzin on earthworm Eisenia fetida: Survival, oxidative stress responses and joint effect","volume":"178","author":"Cao","year":"2022","journal-title":"Appl. Soil Ecol."},{"key":"10.1016\/j.ecoenv.2026.120665_bib9","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/S0043-1354(01)00462-6","article-title":"Pesticides in Portuguese surface and ground waters","volume":"37","author":"Cerejeira","year":"2003","journal-title":"Water Res."},{"key":"10.1016\/j.ecoenv.2026.120665_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.116545","article-title":"Aqueous chlorination of herbicide metribuzin: Identification and elucidation of \"new\" disinfection by-products, degradation pathway and toxicity evaluation","volume":"189","author":"de Barros","year":"2021","journal-title":"Water Res."},{"issue":"7","key":"10.1016\/j.ecoenv.2026.120665_bib11","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.3390\/agronomy13071777","article-title":"Ecotoxicological Evaluation of earthworm (Eisenia fetida) induced by enrofloxacin and di-(2-ethylhexyl) phthalate","volume":"13","author":"Gao","year":"2023","journal-title":"Agronomy"},{"key":"10.1016\/j.ecoenv.2026.120665_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.134771","article-title":"Nickel oxide nanoparticles decrease the accumulation of atrazine in earthworms","volume":"474","author":"Gao","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2026.120665_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.pestbp.2024.106215","article-title":"Fomesafen induced ecotoxicological responses, bioaccumulation, and implications for soil ecosystems remediation in three ecotypes earthworms","volume":"207","author":"Ge","year":"2025","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.ecoenv.2026.120665_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2025.118128","article-title":"Metabolomics reveals increased toxicity in earthworms (Eisenia fetida) of the transformation product methyl-Triclosan","volume":"294","author":"Gillis","year":"2025","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"54","key":"10.1016\/j.ecoenv.2026.120665_bib15","doi-asserted-by":"crossref","first-page":"116004","DOI":"10.1007\/s11356-023-30608-3","article-title":"Phytotoxicity alleviation of imazethapyr to Non-target plant wheat: Active regulation between auxin and DIMBOA","volume":"30","author":"Huang","year":"2023","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.ecoenv.2026.120665_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.129817","article-title":"The toxic effects of chronic atrazine exposure on the intestinal microbiota, metabolism and transcriptome of Pelophylax nigromaculatus larvae","volume":"440","author":"Huang","year":"2022","journal-title":"J. Hazard. Mater."},{"issue":"32","key":"10.1016\/j.ecoenv.2026.120665_bib17","doi-asserted-by":"crossref","first-page":"17813","DOI":"10.1021\/acs.jafc.4c02089","article-title":"Novel inhibitor of glutamate-cysteine ligase catalytic subunit against Tribolium castaneum: High-throughout virtual screening, molecular docking and dynamics simulation, and bioassay","volume":"72","author":"Kim","year":"2024","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.ecoenv.2026.120665_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.etap.2025.104713","article-title":"Combined exposure to atrazine and phoxim exacerbated the alterations of enzyme activity and abnormal gene expression in earthworms (Eisenia fetida)","volume":"116","author":"Li","year":"2025","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.ecoenv.2026.120665_bib19","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.chemosphere.2019.05.215","article-title":"Combination of chemical and toxicological methods to assess bioavailability of Tolclofos-methyl by earthworms","volume":"233","author":"Li","year":"2019","journal-title":"Chemosphere"},{"issue":"4","key":"10.1016\/j.ecoenv.2026.120665_bib20","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.bbadis.2016.01.003","article-title":"ROS\/oxidative stress signaling in osteoarthritis","volume":"1862","author":"Lepetsos","year":"2016","journal-title":"Biochim. Biophys. Acta Mol. Basis Dis."},{"key":"10.1016\/j.ecoenv.2026.120665_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecolind.2020.106465","article-title":"Biochemical response, histopathological change and DNA damage in earthworm (Eisenia fetida) exposed to sulfentrazone herbicide","volume":"115","author":"Li","year":"2020","journal-title":"Ecol. Indic."},{"key":"10.1016\/j.ecoenv.2026.120665_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpc.2021.109250","article-title":"Ecotoxicity of herbicide carfentrazone-ethyl towards earthworm Eisenia fetida in soil","volume":"253","author":"Li","year":"2022","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.ecoenv.2026.120665_bib23","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.chemosphere.2015.04.058","article-title":"Toxicity and bioaccumulation of bromadiolone to earthworm Eisenia fetida","volume":"135","author":"Liu","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2026.120665_bib24","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.ecoenv.2017.04.012","article-title":"Oxidative stress and gene expression of earthworm (Eisenia fetida) to clothianidin","volume":"142","author":"Liu","year":"2017","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2026.120665_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.121584","article-title":"Responses and detoxification mechanisms of earthworm Amynthas hupeiensis to metal contaminated soils of North China","volume":"327","author":"Liu","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2026.120665_bib26","doi-asserted-by":"crossref","first-page":"8583","DOI":"10.1038\/s41598-023-35225-1","article-title":"GC-MS based untargeted metabolomics reveals the metabolic response of earthworm (Eudrilus eugeniae) after chronic combinatorial exposure to three different pesticides","volume":"13","author":"Malla","year":"2023","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ecoenv.2026.120665_bib27","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.geoderma.2019.02.009","article-title":"Cow bone char as a sorbent to increase sorption and decrease mobility of hexazinone, metribuzin, and quinclorac in soil","volume":"343","author":"Mendes","year":"2019","journal-title":"Geoderma"},{"key":"10.1016\/j.ecoenv.2026.120665_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2023.122109","article-title":"Spermidine suppresses oxidative stress and ferroptosis by Nrf2\/HO-1\/GPX4 and Akt\/FHC\/ACSL4 pathway to alleviate ovarian damage","volume":"332","author":"Niu","year":"2023","journal-title":"Life Sci."},{"key":"10.1016\/j.ecoenv.2026.120665_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.jenvman.2022.115989","article-title":"Oxidative stress and detoxification mechanisms of earthworms (Eisenia fetida) after exposure to flupyradifurone in a soil-earthworm System","volume":"322","author":"Qiao","year":"2022","journal-title":"J. Environ. Manag."},{"key":"10.1016\/j.ecoenv.2026.120665_bib30","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.envpol.2015.03.002","article-title":"Pesticide leaching through sandy and loamy fields\u2014Long-term lessons learnt from the Danish Pesticide Leaching Assessment Programme","volume":"201","author":"Rosenbom","year":"2015","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2026.120665_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.etap.2025.104811","article-title":"Insights into the chronic toxicity and mechanisms of Fluorine-containing pesticides on earthworms","volume":"119","author":"Shan","year":"2025","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.ecoenv.2026.120665_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2023.117379","article-title":"Effects of the polyhalogenated carbazoles 3-bromocarbazole and 1,3,6,8-tetrabromocarbazole on soil microbial communities","volume":"239","author":"Shi","year":"2023","journal-title":"Environ. Res."},{"key":"10.1016\/j.ecoenv.2026.120665_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2025.138962","article-title":"3,6-dibromocarbazole have a significant effect on diversity, community and function of soil microorganisms","volume":"495","author":"Shi","year":"2025","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2026.120665_bib34","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/j.soilbio.2008.09.009","article-title":"DNA damage and effects on antioxidative enzymes in earthworm (Eisenia fetida) induced by atrazine","volume":"41","author":"Song","year":"2009","journal-title":"Soil Biol. Biochem."},{"key":"10.1016\/j.ecoenv.2026.120665_bib35","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/s11306-025-02236-0","article-title":"Vitamin B6 deficiency produces metabolic alterations in Drosophila","volume":"21","author":"Tesoriere","year":"2025","journal-title":"Metabolomics"},{"key":"10.1016\/j.ecoenv.2026.120665_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2020.109184","article-title":"Scoulerine promotes cell viability reduction and apoptosis by activating ROS-dependent endoplasmic reticulum stress in colorectal cancer cells","volume":"327","author":"Tian","year":"2020","journal-title":"Chem. -Biol. Interact."},{"key":"10.1016\/j.ecoenv.2026.120665_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpc.2021.109145","article-title":"Ecotoxicity of chlorpyrifos on earthworm Eisenia fetida (Savigny, 1826): Modifications in oxidative Biomarkers","volume":"249","author":"Torabi Farsani","year":"2021","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.ecoenv.2026.120665_bib38","doi-asserted-by":"crossref","DOI":"10.1128\/ecosalplus.ESP-0004-2021","article-title":"Knowns and unknowns of vitamin B6 metabolism in\u00a0Escherichia coli","volume":"9","author":"Tramonti","year":"2021","journal-title":"EcoSal Plus."},{"issue":"3","key":"10.1016\/j.ecoenv.2026.120665_bib39","doi-asserted-by":"crossref","first-page":"117","DOI":"10.17221\/811\/2016-PSE","article-title":"Effects of the herbicides benfluralin, metribuzin and propyzamide on the survival and weight of earthworms (Octodrilus complanatus)","volume":"63","author":"Travlos","year":"2017","journal-title":"Plant. Soil Environ."},{"key":"10.1016\/j.ecoenv.2026.120665_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2019.125512","article-title":"Biochemical responses and DNA damage induced by herbicide QYR301 in earthworm (Eisenia fetida)","volume":"244","author":"Wang","year":"2020","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2026.120665_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2024.124554","article-title":"Pseudomonas putida HE alleviates glyphosate-induced toxicity in earthworm: Insights from the neurological, reproductive and immunological status","volume":"359","author":"Wang","year":"2024","journal-title":"Environ. Pollut."},{"issue":"6","key":"10.1016\/j.ecoenv.2026.120665_bib42","doi-asserted-by":"crossref","first-page":"6175","DOI":"10.1007\/s13762-022-04348-9","article-title":"Ecotoxicity of herbicide diuron on the earthworm Eisenia fetida: Oxidative stress, histopathology, and DNA Damage","volume":"20","author":"Wang","year":"2022","journal-title":"Int. J. Environ. Sci. Technol."},{"issue":"4","key":"10.1016\/j.ecoenv.2026.120665_bib43","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.chemosphere.2012.02.086","article-title":"Toxicity assessment of 45 pesticides to the epigeic earthworm Eisenia fetida","volume":"88","author":"Wang","year":"2012","journal-title":"Chemosphere"},{"issue":"2","key":"10.1016\/j.ecoenv.2026.120665_bib44","article-title":"Oxidative stress and DNA damage in earthworm (Eisenia fetida) induced by triflumezopyrim exposure","volume":"264","author":"Wen","year":"2021","journal-title":"Chemosphere"},{"issue":"10","key":"10.1016\/j.ecoenv.2026.120665_bib45","doi-asserted-by":"crossref","first-page":"808","DOI":"10.3390\/toxics11100808","article-title":"Fluopicolide-induced oxidative stress and DNA damage in the earthworm Eisenia foetida","volume":"11","author":"Wen","year":"2023","journal-title":"Toxics"},{"key":"10.1016\/j.ecoenv.2026.120665_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.138023","article-title":"Effect of different exposure times and doses of cyantraniliprole on oxidative stress and genotoxicity in earthworms (Eisenia fetida)","volume":"319","author":"Xue","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2026.120665_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.141873","article-title":"Oxidative stress, growth inhibition, and DNA damage in earthworms induced by the combined pollution of typical neonicotinoid insecticides and heavy Metals","volume":"754","author":"Yan","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2026.120665_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2024.116223","article-title":"Environmental-related doses of afidopyropen induced toxicity effects in earthworms (Eisenia fetida)","volume":"274","author":"Yin","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2026.120665_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.115824","article-title":"Toxicological effects induced by two carbamates on earthworms (Eisenia fetida): Acute toxicity, arrested regeneration and underlying mechanisms","volume":"269","author":"Yuan","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2026.120665_bib50","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1007\/s10646-012-0884-5","article-title":"Coelomic fluid: a complimentary biological medium to assess sub-lethal endosulfan exposure using 1H NMR-based earthworm metabolomics","volume":"21","author":"Yuk","year":"2012","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.ecoenv.2026.120665_bib51","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.scitotenv.2018.06.091","article-title":"Evaluating subchronic toxicity of fluoxastrobin using earthworms (Eisenia fetida)","volume":"642","author":"Zhang","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ecoenv.2026.120665_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.113796","article-title":"Sub-chronic ecotoxicity of triphenyl phosphate to earthworms (Eisenia fetida) in artificial soil: oxidative stress and DNA damage","volume":"241","author":"Zhang","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2026.120665_bib53","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.chemosphere.2015.05.091","article-title":"Toxicological effects of soil contaminated with spirotetramat to the earthworm Eisenia fetida","volume":"139","author":"Zhang","year":"2015","journal-title":"Chemosphere"},{"issue":"2","key":"10.1016\/j.ecoenv.2026.120665_bib54","article-title":"Oxidative stress and genotoxicity of nitenpyram to earthworms (Eisenia foetida)","volume":"264","author":"Zhang","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2026.120665_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.132182","article-title":"Phthalates (PAEs) and reproductive toxicity: Hypothalamic-pituitary-gonadal (HPG) axis aspects","volume":"459","author":"Zhang","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2026.120665_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.114706","article-title":"Use of integrated biomarker response for evaluating antioxidant stress and DNA damage of earthworms (Eisenia fetida) in decabromodiphenyl ethane-contaminated soil","volume":"264","author":"Zhao","year":"2020","journal-title":"Environ. Pollut."},{"issue":"19","key":"10.1016\/j.ecoenv.2026.120665_bib57","doi-asserted-by":"crossref","first-page":"27679","DOI":"10.1007\/s11356-024-32964-0","article-title":"Oxidative stress, DNA damage, and gene expression in earthworms (Eisenia fetida) exposure to ethiprole","volume":"31","author":"Zhou","year":"2024","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.ecoenv.2026.120665_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.126982","article-title":"Acute toxicity, oxidative stress and DNA damage of chlorpyrifos to earthworms (Eisenia fetida): the difference between artificial and natural soils","volume":"255","author":"Zhu","year":"2020","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2026.120665_bib59","doi-asserted-by":"crossref","first-page":"14579","DOI":"10.1021\/acs.est.5b03849","article-title":"Environmentally relevant concentrations of the flame retardant tris (1,3-dichloro-2-propyl) phosphate inhibit growth of female zebrafish and decrease fecundity","volume":"49","author":"Zhu","year":"2015","journal-title":"Environ. Sci. Technol."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651326009954?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651326009954?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T17:31:45Z","timestamp":1793554305000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651326009954"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":59,"alternative-id":["S0147651326009954"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2026.120665","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Biological and metabolism responses of earthworm (Eisenia fetida) exposed to metribuzin","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2026.120665","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"120665"}}