{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T05:45:46Z","timestamp":1792129546222,"version":"4.4.0"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:00Z","timestamp":1789689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012154","name":"Graduate Research and Innovation Projects of Jiangsu Province","doi-asserted-by":"publisher","award":["SJCX24_0242"],"award-info":[{"award-number":["SJCX24_0242"]}],"id":[{"id":"10.13039\/501100012154","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008562","name":"Nanjing Agricultural University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008562","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["YDZX2026012"],"award-info":[{"award-number":["YDZX2026012"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.ecoenv.2026.120823","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T09:10:52Z","timestamp":1790068252000},"page":"120823","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Biointerface interactions and mechanistic ecotoxicity of polystyrene micro\/nanoplastics and imidacloprid in juvenile Carassius auratus under single and combined exposure"],"prefix":"10.1016","volume":"324","author":[{"given":"Zhaoxuan","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinzi","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyuan","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiasen","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuocheng","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aibing","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawei","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingxing","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2026.120823_bib1","doi-asserted-by":"crossref","first-page":"6858","DOI":"10.1073\/pnas.78.11.6858","article-title":"Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis","volume":"78","author":"Ames","year":"1981","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.ecoenv.2026.120823_bib2","doi-asserted-by":"crossref","first-page":"336","DOI":"10.3390\/toxics13050336","article-title":"Effects of polystyrene nanoplastics on oxidative stress, blood biochemistry, and digestive enzyme activity in goldfish (Carassius auratus)","volume":"13","author":"Azarm-Karnagh","year":"2025","journal-title":"Toxics"},{"key":"10.1016\/j.ecoenv.2026.120823_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2024.116822","article-title":"Combined transcriptome and metabolome analysis reveals the toxic effects of antimony on the earthworm","volume":"283","author":"Bai","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2026.120823_bib4","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.aquaculture.2017.04.025","article-title":"Xanthine oxidase activity exerts a pro-oxidant and pro-inflammatory profile in gills of experimentally infected silver catfish with Streptococcus agalactiae","volume":"477","author":"Baldissera","year":"2017","journal-title":"Aquaculture"},{"key":"10.1016\/j.ecoenv.2026.120823_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.150709","article-title":"Microplastics in agricultural drainage water: a link between terrestrial and aquatic microplastic pollution","volume":"806","author":"Bigalke","year":"2022","journal-title":"Sci. Total. Environ."},{"key":"10.1016\/j.ecoenv.2026.120823_bib6","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s12302-025-01104-x","article-title":"Microplastics and nanoplastics: fate, transport, and governance from agricultural soil to food webs and humans","volume":"37","author":"Boctor","year":"2025","journal-title":"Environ. Sci. Eur."},{"key":"10.1016\/j.ecoenv.2026.120823_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00360-016-1026-9","article-title":"A broader look at ammonia production, excretion, and transport in fish: a review of impacts of feeding and the environment","volume":"187","author":"Bucking","year":"2017","journal-title":"J. Comp. Physiol. B"},{"key":"10.1016\/j.ecoenv.2026.120823_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2022.108470","article-title":"Polyethylene microplastics trigger cell apoptosis and inflammation via inducing oxidative stress and activation of the NLRP3 inflammasome in carp gills","volume":"132","author":"Cao","year":"2023","journal-title":"Fish. & Shellfish. Immunol."},{"key":"10.1016\/j.ecoenv.2026.120823_bib9","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.ecoenv.2019.06.038","article-title":"Environmental risk assessment of pesticides in tropical terrestrial ecosystems: Test procedures, current status and future perspectives","volume":"181","author":"Daam","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2026.120823_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2024.117332","article-title":"Microplastics in soil: A comprehensive review of occurrence, sources, fate, analytical techniques and potential impacts","volume":"288","author":"En-Nejmy","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2026.120823_bib11","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1152\/physrev.00050.2003","article-title":"The multifunctional fish gill: dominant site of gas exchange, osmoregulation, acid-base regulation, and excretion of nitrogenous waste","volume":"85","author":"Evans","year":"2005","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.ecoenv.2026.120823_bib12","article-title":"Co-exposure toxicity of microplastic and sumithion in Nile tilapia \u2013 changes in growth, hematology, histopathology of internal tissues and immune-antioxidant genes expression","volume":"19","author":"Haque","year":"2025","journal-title":"J. Hazard. Mater. Adv."},{"key":"10.1016\/j.ecoenv.2026.120823_bib13","doi-asserted-by":"crossref","first-page":"385","DOI":"10.3390\/fishes9100385","article-title":"Effect of Polystyrene Microplastic Exposure on Individual, Tissue, and Gene Expression in Juvenile Crucian Carp (Carassius auratus)","volume":"9","author":"Huang","year":"2024","journal-title":"Fishes"},{"key":"10.1016\/j.ecoenv.2026.120823_bib14","doi-asserted-by":"crossref","first-page":"134","DOI":"10.3389\/fphys.2010.00134","article-title":"S.F. Chew, Ammonia production, excretion, toxicity, and defense in fish: a review","volume":"1","author":"Ip","year":"2010","journal-title":"Front. Physiol."},{"key":"10.1016\/j.ecoenv.2026.120823_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.120858","article-title":"Current levels and composition profiles of microplastics in irrigation water","volume":"318","author":"Jiang","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2026.120823_bib16","doi-asserted-by":"crossref","DOI":"10.14814\/phy2.16138","article-title":"Exposure to neonicotinoid pesticides induces physiological disorders and affects color performance and foraging behavior in goldfish","volume":"12","author":"Kakuta","year":"2024","journal-title":"Physiol. Rep."},{"key":"10.1016\/j.ecoenv.2026.120823_bib17","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.freeradbiomed.2009.11.012","article-title":"Hydrogen peroxide is the major oxidant product of xanthine oxidase","volume":"48","author":"Kelley","year":"2010","journal-title":"Free. Radic. Biol. Med."},{"key":"10.1016\/j.ecoenv.2026.120823_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.128556","article-title":"Adsorption of three pesticides on polyethylene microplastics in aqueous solutions: Kinetics, isotherms, thermodynamics, and molecular dynamics simulation","volume":"264","author":"Li","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2026.120823_bib19","article-title":"Mass concentration, spatial distribution, and risk assessment of small microplastics (1\u2013100 \u03bcm) and nanoplastics (<1 \u03bcm) in the surface water of Taihu Lake, China","volume":"285","author":"Li","year":"2025","journal-title":"Environ. Res."},{"key":"10.1016\/j.ecoenv.2026.120823_bib20","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.3390\/genes13112130","article-title":"WGCNA Analysis Revealed the Hub Genes Related to Soil Cadmium Stress in Maize Kernel (Zea mays L.)","volume":"13","author":"Li","year":"2022","journal-title":"Genes"},{"key":"10.1016\/j.ecoenv.2026.120823_bib21","doi-asserted-by":"crossref","first-page":"9469","DOI":"10.1021\/acsnano.1c02407","article-title":"Nanoplastic-Induced Genotoxicity and Intestinal Damage in Freshwater Benthic Clams (Corbicula fluminea): Comparison with Microplastics","volume":"15","author":"Li","year":"2021","journal-title":"ACS Nano"},{"key":"10.1016\/j.ecoenv.2026.120823_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecolind.2021.108385","article-title":"Ecosystem services analysis for sustainable agriculture expansion: Rice-fish co-culture system breaking through the Hu Line","volume":"133","author":"Liu","year":"2021","journal-title":"Ecol. Indic."},{"key":"10.1016\/j.ecoenv.2026.120823_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.126915","article-title":"Environmental behaviors of microplastics in aquatic systems: A systematic review on degradation, adsorption, toxicity and biofilm under aging conditions","volume":"423","author":"Luo","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2026.120823_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpc.2021.109043","article-title":"Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription","volume":"246","author":"Luo","year":"2021","journal-title":"Comparative Biochemistry Physiology Part C Toxicology & Pharmacology"},{"key":"10.1016\/j.ecoenv.2026.120823_bib25","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1016\/j.scitotenv.2018.10.321","article-title":"Microplastic pollution in rice-fish co-culture system: A report of three farmland stations in Shanghai, China","volume":"652","author":"Lv","year":"2019","journal-title":"Sci. Total. Environ."},{"key":"10.1016\/j.ecoenv.2026.120823_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.120513","article-title":"Microplastic appraisal of soil, water, ditch sediment and airborne dust: The case of agricultural systems","volume":"316","author":"Lwanga","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2026.120823_bib27","doi-asserted-by":"crossref","first-page":"26702","DOI":"10.1021\/acs.est.5c07311","article-title":"Imidacloprid in United States Rivers, 2013-2022: Persistent Presence and Emerging Chronic Hazard","volume":"59","author":"Miller","year":"2025","journal-title":"Environ. Sci. & Technol."},{"key":"10.1016\/j.ecoenv.2026.120823_bib28","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.envint.2014.10.024","article-title":"Neonicotinoid contamination of global surface waters and associated risk to aquatic invertebrates: A review","volume":"74","author":"Morrissey","year":"2015","journal-title":"Environ. Int."},{"key":"10.1016\/j.ecoenv.2026.120823_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2025.144423","article-title":"Microplastics in rice-based farming systems and their connection to plastic waste management in the Chicoral district of Espinal-Tolima","volume":"378","author":"Mu\u00f1oz Yustres","year":"2025","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2026.120823_bib30","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1096\/fj.06-6834com","article-title":"Ammonia secretion from fish gill depends on a set of Rh glycoproteins","volume":"21","author":"Nakada","year":"2007","journal-title":"FASEB J."},{"key":"10.1016\/j.ecoenv.2026.120823_bib31","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1152\/physiolgenomics.00061.2007","article-title":"Ammonia excretion in rainbow trout (Oncorhynchus mykiss): evidence for Rh glycoprotein and H+-ATPase involvement","volume":"31","author":"Nawata","year":"2007","journal-title":"Physiol. Genom."},{"key":"10.1016\/j.ecoenv.2026.120823_bib32","doi-asserted-by":"crossref","first-page":"24888","DOI":"10.1074\/jbc.M501830200","article-title":"Mechanism of the conversion of xanthine dehydrogenase to xanthine oxidase: identification of the two cysteine disulfide bonds and crystal structure of a non-convertible rat liver xanthine dehydrogenase mutant","volume":"280","author":"Nishino","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ecoenv.2026.120823_bib33","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0069461","article-title":"Exploring Early Micronutrient Deficiencies in Rainbow Trout (Oncorhynchus mykiss) by Next-Generation Sequencing Technology \u2013 From Black Box to Functional Genomics","volume":"8","author":"Olsvik","year":"2013","journal-title":"PLOS ONE"},{"key":"10.1016\/j.ecoenv.2026.120823_bib34","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.toxrep.2017.12.019","article-title":"Imidacloprid exposure cause the histopathological changes, activation of TNF-\u03b1, iNOS, 8-OHdG biomarkers, and alteration of caspase 3, iNOS, CYP1A, MT1 gene expression levels in common carp (Cyprinus carpio L.)","volume":"5","author":"\u00d6zdemir","year":"2018","journal-title":"Toxicol. Rep."},{"key":"10.1016\/j.ecoenv.2026.120823_bib35","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abc6050","article-title":"The gill-oxygen limitation theory (GOLT) and its critics","volume":"7","author":"Pauly","year":"2021","journal-title":"Sci. Adv."},{"key":"10.1016\/j.ecoenv.2026.120823_bib36","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s11270-008-9953-z","article-title":"Fate and Transport of Nursery-Box-Applied Tricyclazole and Imidacloprid in Paddy Fields","volume":"202","author":"Phong","year":"2009","journal-title":"Water Air Soil. Pollut."},{"key":"10.1016\/j.ecoenv.2026.120823_bib37","series-title":"Sublethal and Chronic Effects of Pollutants on Freshwater Fish","first-page":"339","article-title":"V. Mitrovic-Tutundzic, Fish gills as a monitor of sublethal and chronic effects of pollution","author":"Poleksic","year":"1994"},{"key":"10.1016\/j.ecoenv.2026.120823_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.151642","article-title":"Effects of virgin and weathered polystyrene and polypropylene microplastics on Raphidocelis subcapitata and embryos of Danio rerio under environmental concentrations","volume":"816","author":"Prata","year":"2022","journal-title":"Sci. Total. Environ."},{"key":"10.1016\/j.ecoenv.2026.120823_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.166935","article-title":"Occurrence and characteristics of microplastics in soils from greenhouse and open-field cultivation using plastic mulch film","volume":"905","author":"Qi","year":"2023","journal-title":"Sci. Total. Environ."},{"key":"10.1016\/j.ecoenv.2026.120823_bib40","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1016\/j.cbpa.2007.03.007","article-title":"The functional ontogeny of the teleost gill: Which comes first, gas or ion exchange?","volume":"148","author":"Rombough","year":"2007","journal-title":"Comparative Biochemistry Physiology Part A Molecular & Integrative Physiology"},{"key":"10.1016\/j.ecoenv.2026.120823_bib41","doi-asserted-by":"crossref","first-page":"12927","DOI":"10.3390\/ijerph111212927","article-title":"Histological Changes in Gills of Two Fish Species as Indicators of Water Quality in Jansen Lagoon (S\u00e3o Lu\u00eds, Maranh\u00e3o State, Brazil)","volume":"11","author":"Santos","year":"2014","journal-title":"Int. J. Environ. Res. Public. Health"},{"key":"10.1016\/j.ecoenv.2026.120823_bib42","doi-asserted-by":"crossref","first-page":"8413","DOI":"10.1038\/s41467-024-52734-3","article-title":"Plastic pollution in agricultural landscapes: an overlooked threat to pollination, biocontrol and food security","volume":"15","author":"Sheng","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ecoenv.2026.120823_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2024.121660","article-title":"Combined exposure of emamectin benzoate and microplastics induces tight junction disorder, immune disorder and inflammation in carp midgut via lysosome\/ROS\/ferroptosis pathway","volume":"257","author":"Shi","year":"2024","journal-title":"Water Res."},{"key":"10.1016\/j.ecoenv.2026.120823_bib44","doi-asserted-by":"crossref","first-page":"C1625","DOI":"10.1152\/ajpcell.00255.2008","article-title":"Ammonia excretion by the skin of zebrafish (Danio rerio) larvae","volume":"295","author":"Shih","year":"2008","journal-title":"Am. J. Physiol. -Cell. Physiol."},{"key":"10.1016\/j.ecoenv.2026.120823_bib45","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1007\/s00128-011-0515-5","article-title":"Detections of the Neonicotinoid Insecticide Imidacloprid in Surface Waters of Three Agricultural Regions of California, USA, 2010-2011","volume":"88","author":"Starner","year":"2012","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.ecoenv.2026.120823_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.137856","article-title":"Pesticide residues in agricultural topsoil from the Hainan tropical riverside basin: Determination, distribution, and relationships with planting patterns and surface water","volume":"722","author":"Tan","year":"2020","journal-title":"Sci. Total. Environ."},{"key":"10.1016\/j.ecoenv.2026.120823_bib47","doi-asserted-by":"crossref","first-page":"3602","DOI":"10.1016\/j.cell.2024.05.011","article-title":"De novo and salvage purine synthesis pathways across tissues and tumors","volume":"187","author":"Tran","year":"2024","journal-title":"Cell"},{"key":"10.1016\/j.ecoenv.2026.120823_bib48","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0062374","article-title":"Macro-Invertebrate Decline in Surface Water Polluted with Imidacloprid","volume":"8","author":"Van Dijk","year":"2013","journal-title":"PLOS ONE"},{"key":"10.1016\/j.ecoenv.2026.120823_bib49","doi-asserted-by":"crossref","first-page":"584","DOI":"10.3390\/molecules27030584","article-title":"Microplastics (Polystyrene) Exposure Induces Metabolic Changes in the Liver of Rare Minnow (Gobiocypris rarus)","volume":"27","author":"Wang","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.ecoenv.2026.120823_bib50","doi-asserted-by":"crossref","first-page":"2303","DOI":"10.1242\/jeb.023085","article-title":"A new paradigm for ammonia excretion in aquatic animals: role of Rhesus (Rh) glycoproteins","volume":"212","author":"Wright","year":"2009","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.ecoenv.2026.120823_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2021.737541","article-title":"Waterborne enrofloxacin exposure activated oxidative stress and MAPK pathway, induced apoptosis and resulted in immune dysfunction in the gills of yellow catfish Pelteobagrus fulvidraco","volume":"547","author":"Xu","year":"2022","journal-title":"Aquaculture"},{"key":"10.1016\/j.ecoenv.2026.120823_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.133181","article-title":"Microplastics and nanoplastics induced differential respiratory damages in tilapia fish Oreochromis niloticus","volume":"465","author":"Zheng","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2026.120823_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2025.137471","article-title":"Differential effects of foodborne and waterborne micro(nano)plastics exposure on fish liver metabolism and gut microbiota community","volume":"488","author":"Zheng","year":"2025","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2026.120823_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.159353","article-title":"Disturbing ion regulation and excretion in medaka (Oryzias melastigma) gills by microplastics: insights from the gut-gill axis","volume":"857","author":"Zheng","year":"2023","journal-title":"Sci. Total. Environ."},{"key":"10.1016\/j.ecoenv.2026.120823_bib55","doi-asserted-by":"crossref","first-page":"5974","DOI":"10.1021\/acs.est.3c10338","article-title":"Single-cell RNA sequencing profiling cellular heterogeneity and specific responses of fish gills to microplastics and nanoplastics","volume":"58","author":"Zheng","year":"2024","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ecoenv.2026.120823_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.135620","article-title":"Contrasting the distribution kinetics of microplastics and nanoplastics in medaka following exposure and depuration","volume":"478","author":"Zheng","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2026.120823_bib57","doi-asserted-by":"crossref","first-page":"2767","DOI":"10.3390\/w14172767","article-title":"Long-term exposure to polystyrene nanoplastics impairs the liver health of medaka","volume":"14","author":"Zhou","year":"2022","journal-title":"Water"}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014765132601153X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014765132601153X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T04:59:06Z","timestamp":1792126746000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S014765132601153X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":57,"alternative-id":["S014765132601153X"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2026.120823","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Biointerface interactions and mechanistic ecotoxicity of polystyrene micro\/nanoplastics and imidacloprid in juvenile Carassius auratus under single and combined exposure","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2026.120823","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"120823"}}