{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T23:24:31Z","timestamp":1793921071457,"version":"4.8.0"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T00:00:00Z","timestamp":1789862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.ecoenv.2026.120830","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T08:17:31Z","timestamp":1790237851000},"page":"120830","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Putative role of NF-\u03baB-mediated inflammation in acute cardiac injury induced by S-band microwave radiation in rats"],"prefix":"10.1016","volume":"324","author":[{"given":"Chenjing","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weilin","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binwei","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hailong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinping","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiyun","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.ecoenv.2026.120830_bib1","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.tcm.2022.02.005","article-title":"Myocardial ischemia-reperfusion injury and the influence of inflammation","volume":"33","author":"Algoet","year":"2023","journal-title":"Trends Cardiovasc. Med."},{"issue":"12","key":"10.1016\/j.ecoenv.2026.120830_bib2","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2014.524","article-title":"Caspase-1 cleavage of transcription factor GATA4 and regulation of cardiac cell fate","volume":"5","author":"Aries","year":"2014","journal-title":"Cell. Death Dis."},{"issue":"21","key":"10.1016\/j.ecoenv.2026.120830_bib3","doi-asserted-by":"crossref","first-page":"11596","DOI":"10.3390\/ijms252111596","article-title":"Pathological alterations in heart mitochondria in a rat model of isoprenaline-induced myocardial injury and their correction with water-soluble taxifolin","volume":"25","author":"Belosludtseva","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"3","key":"10.1016\/j.ecoenv.2026.120830_bib4","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.ijcard.2011.11.099","article-title":"Osteoprotegerin\/RANK\/RANKL axis and atrial remodeling in mitral valvular patients with atrial fibrillation","volume":"166","author":"Cao","year":"2013","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ecoenv.2026.120830_bib5","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.yjmcc.2021.07.002","article-title":"Early adaptive chromatin remodeling events precede pathologic phenotypes and are reinforced in the failing heart","volume":"160","author":"Chapski","year":"2021","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"21","key":"10.1016\/j.ecoenv.2026.120830_bib6","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1161\/CIRCULATIONAHA.117.028202","article-title":"Delayed repolarization underlies ventricular arrhythmias in rats with heart failure and preserved ejection fraction","volume":"136","author":"Cho","year":"2017","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.ecoenv.2026.120830_bib7","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1007\/s10741-021-10153-2","article-title":"Osteoprotegerin and RANKL-RANK-OPG-TRAIL signalling axis in heart failure and other cardiovascular diseases","volume":"27","author":"Dutka","year":"2022","journal-title":"Heart Fail. Rev."},{"key":"10.1016\/j.ecoenv.2026.120830_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.carpath.2024.107670","article-title":"Ultrastructural cardiac pathology: the wide (yet so very small) world of cardiac electron microscopy","volume":"73","author":"Fishbein","year":"2024","journal-title":"Cardiovasc. Pathol."},{"issue":"2","key":"10.1016\/j.ecoenv.2026.120830_bib9","doi-asserted-by":"crossref","first-page":"920","DOI":"10.3390\/ijerph19020920","article-title":"Exposure Assessment to Radiofrequency Electromagnetic Fields in Occupational Military Scenarios: A Review","volume":"19","author":"Gallucci","year":"2022","journal-title":"Int. J. Environ. Res. Public. Health"},{"issue":"1","key":"10.1016\/j.ecoenv.2026.120830_bib10","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1093\/cvr\/cvq274","article-title":"Cardiomyocyte NF-\u03baB p65 promotes adverse remodelling, apoptosis, and endoplasmic reticulum stress in heart failure","volume":"89","author":"Hamid","year":"2011","journal-title":"Cardiovasc. Res."},{"issue":"17","key":"10.1016\/j.ecoenv.2026.120830_bib11","doi-asserted-by":"crossref","first-page":"10146","DOI":"10.3390\/ijms231710146","article-title":"Dapagliflozin Mitigates Doxorubicin-Caused Myocardium Damage by Regulating AKT-Mediated Oxidative Stress, Cardiac Remodeling, and Inflammation","volume":"23","author":"Hsieh","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.ecoenv.2026.120830_bib12","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s13293-017-0152-8","article-title":"The protective role of estrogen and estrogen receptors in cardiovascular disease and the controversial use of estrogen therapy","volume":"8","author":"Iorga","year":"2017","journal-title":"Biol. Sex. Differ."},{"key":"10.1016\/j.ecoenv.2026.120830_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155655","article-title":"Podophyllotoxin via SIRT1\/PPAR\/NF-\u03baB axis induced cardiac injury in rats based on the toxicological evidence chain (TEC) concept","volume":"130","author":"Jiang","year":"2024","journal-title":"Phytomedicine"},{"issue":"3","key":"10.1016\/j.ecoenv.2026.120830_bib14","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1089\/jmf.2004.7.299","article-title":"Green tea catechins protect rats from microwave-induced oxidative damage to heart tissue","volume":"7","author":"Kim","year":"2004","journal-title":"J. Med. Food"},{"issue":"7","key":"10.1016\/j.ecoenv.2026.120830_bib15","doi-asserted-by":"crossref","first-page":"6237","DOI":"10.3390\/ijms24076237","article-title":"Physiological and Psychological Stress of Microwave Radiation-Induced Cardiac Injury in Rats","volume":"24","author":"Li","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"10.1016\/j.ecoenv.2026.120830_bib16","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.7150\/ijms.107667","article-title":"Discovery and confirmation of crucial genes associated with radiation-induced heart disease","volume":"22","author":"Liu","year":"2025","journal-title":"Int. J. Med. Sci."},{"issue":"21","key":"10.1016\/j.ecoenv.2026.120830_bib17","first-page":"6670","article-title":"PM2.5-induced inflammation and myocardial cell injury in rats","volume":"25","author":"Ma","year":"2021","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"2","key":"10.1016\/j.ecoenv.2026.120830_bib18","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/S0002-9440(10)61739-7","article-title":"Dynamic process of apoptosis in adult rat cardiomyocytes analyzed using 48-hour videomicroscopy and electron microscopy: beating and rate are associated with the apoptotic process","volume":"159","author":"Maruyama","year":"2001","journal-title":"Am. J. Pathol."},{"issue":"1-2","key":"10.1016\/j.ecoenv.2026.120830_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11010-005-9010-9","article-title":"Rat chemokine CXCL11: structure, tissue distribution, function and expression in cardiac transplantation models","volume":"296","author":"Mitsuhashi","year":"2007","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.ecoenv.2026.120830_bib20","doi-asserted-by":"crossref","first-page":"749","DOI":"10.2147\/JIR.S277457","article-title":"Role of Caspase-1 in the Pathogenesis of Inflammatory-Associated Chronic Noncommunicable Diseases","volume":"13","author":"Molla","year":"2020","journal-title":"J. Inflamm. Res."},{"issue":"5","key":"10.1016\/j.ecoenv.2026.120830_bib21","doi-asserted-by":"crossref","DOI":"10.1002\/hsr2.70878","article-title":"Advancements in Biomarkers for Early Detection and Risk Stratification of Cardiovascular Diseases-A Literature Review","volume":"8","author":"Nazir","year":"2025","journal-title":"Health Sci. Rep."},{"issue":"3","key":"10.1016\/j.ecoenv.2026.120830_bib22","doi-asserted-by":"crossref","first-page":"H926","DOI":"10.1152\/ajpheart.00436.2001","article-title":"Differential expression of TNF-alpha, IL-6, and IGF-1 by graded mechanical stress in normal rat myocardium","volume":"282","author":"Palmieri","year":"2002","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"2","key":"10.1016\/j.ecoenv.2026.120830_bib23","doi-asserted-by":"crossref","first-page":"199","DOI":"10.33549\/physiolres.934938","article-title":"Electromagnetic fields - do they pose a cardiovascular risk?","volume":"72","author":"Parizek","year":"2023","journal-title":"Physiol. Res."},{"key":"10.1016\/j.ecoenv.2026.120830_bib24","doi-asserted-by":"crossref","first-page":"92","DOI":"10.3389\/fphys.2020.00092","article-title":"Heart Plasticity in Response to Pressure- and Volume-Overload: A Review of Findings in Compensated and Decompensated Phenotypes","volume":"11","author":"Pitoulis","year":"2020","journal-title":"Front. Physiol."},{"issue":"6","key":"10.1016\/j.ecoenv.2026.120830_bib25","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1111\/anec.12210","article-title":"Correlation of electrocardiogram and regional cardiac magnetic resonance imaging findings in ST-elevation myocardial infarction: a literature review","volume":"19","author":"Rinta-Kiikka","year":"2014","journal-title":"Ann. Noninvasive Electrocardiol."},{"issue":"11","key":"10.1016\/j.ecoenv.2026.120830_bib26","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s11886-018-1067-7","article-title":"Tumor Necrosis Factor-\u03b1 in Heart Failure: an Updated Review","volume":"20","author":"Schumacher","year":"2018","journal-title":"Curr. Cardiol. Rep."},{"issue":"1-2","key":"10.1016\/j.ecoenv.2026.120830_bib27","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3109\/00207459508994290","article-title":"Age-related changes in the noradrenergic pattern and receptor responses of the rat cardiovascular system after repeated microwave exposure","volume":"82","author":"Soldani","year":"1995","journal-title":"Int. J. Neurosci."},{"issue":"2","key":"10.1016\/j.ecoenv.2026.120830_bib28","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s00259-022-05994-4","article-title":"68Ga-FAPI PET visualize heart failure: from mechanism to clinic","volume":"50","author":"Song","year":"2023","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"issue":"15","key":"10.1016\/j.ecoenv.2026.120830_bib29","first-page":"6718","article-title":"Alamandine protects rat from myocardial ischemia-reperfusion injury by activating JNK and inhibiting NF-\u03baB","volume":"23","author":"Song","year":"2019","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"10.1016\/j.ecoenv.2026.120830_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2020.109445","article-title":"Electromagnetic hypersensitivity (EHS, microwave syndrome) - Review of mechanisms","volume":"186","author":"Stein","year":"2020","journal-title":"Environ. Res."},{"issue":"12","key":"10.1016\/j.ecoenv.2026.120830_bib31","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1016\/j.jacep.2023.05.042","article-title":"Unraveling impacts of chamber-specific differences in intercalated disc ultrastructure and molecular organization on cardiac conduction","volume":"9","author":"Struckman","year":"2023","journal-title":"JACC Clin. Electrophysiol."},{"issue":"2","key":"10.1016\/j.ecoenv.2026.120830_bib32","doi-asserted-by":"crossref","first-page":"H594","DOI":"10.1152\/ajpheart.00891.2025","article-title":"Cellular and molecular signals of cardiac wound healing after myocardial infarction","volume":"330","author":"Toba","year":"2026","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"2","key":"10.1016\/j.ecoenv.2026.120830_bib33","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.ijheh.2005.09.008","article-title":"Cardiovascular risk in operators under radiofrequency electromagnetic radiation","volume":"209","author":"Vangelova","year":"2006","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"10.1016\/j.ecoenv.2026.120830_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2024.103223","article-title":"Sweroside alleviates pressure overload-induced heart failure through targeting CaMK\u2161\u03b4 to inhibit ROS-mediated NF-\u03baB\/NLRP3 in cardiomyocytes","volume":"74","author":"Wang","year":"2024","journal-title":"Redox Biol."},{"key":"10.1016\/j.ecoenv.2026.120830_bib35","article-title":"Ramipril attenuates left ventricular remodeling by regulating the expression of activin A-follistatin in a rat model of heart failure","volume":"6","author":"Wei","year":"2016","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.ecoenv.2026.120830_bib36","doi-asserted-by":"crossref","first-page":"119","DOI":"10.3892\/etm.2020.9551","article-title":"Tetrandrine attenuates left ventricular dysfunction in rats with myocardial infarction","volume":"21","author":"Wu","year":"2021","journal-title":"Exp. Ther. Med."},{"issue":"12","key":"10.1016\/j.ecoenv.2026.120830_bib37","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1038\/sj.emboj.7600244","article-title":"Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase","volume":"23","author":"Yeung","year":"2004","journal-title":"EMBO J."},{"key":"10.1016\/j.ecoenv.2026.120830_bib38","article-title":"The role of connexin 43 and related molecules in microwave radiation-induced cardiac electrical conduction abnormalities","author":"Yin","year":"2024","journal-title":"Acad. Mil. Sci."},{"key":"10.1016\/j.ecoenv.2026.120830_bib39","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/3985697","article-title":"Abnormal Expression of Connexin43 in Cardiac Injury Induced by S-Band and X-Band Microwave Exposure in Rats","volume":"2021","author":"Yin","year":"2021","journal-title":"J. Immunol. Res."},{"issue":"16","key":"10.1016\/j.ecoenv.2026.120830_bib40","doi-asserted-by":"crossref","first-page":"12533","DOI":"10.3390\/ijms241612533","article-title":"Role of Cx43 in iPSC-CM Damage Induced by Microwave Radiation","volume":"24","author":"Yin","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ecoenv.2026.120830_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2025.119067","article-title":"A temporal study on NF-\u03baB-mediated autonomous inflammatory response in iPSC-CMs induced by microwave radiation","volume":"303","author":"Zhang","year":"2025","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"7","key":"10.1016\/j.ecoenv.2026.120830_bib42","doi-asserted-by":"crossref","first-page":"H1089","DOI":"10.1152\/ajpheart.00067.2013","article-title":"Cardiomyocyte-specific p65 NF-\u03baB deletion protects the injured heart by preservation of calcium handling","volume":"305","author":"Zhang","year":"2013","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"2","key":"10.1016\/j.ecoenv.2026.120830_bib43","first-page":"249","article-title":"Effect of qindan fuzheng capsule on ultrastructure of microwave radiation injured cardiomyocytes and hepatocytes in rats","volume":"31","author":"Zhong","year":"2011","journal-title":"Zhongguo Zhong Xi Yi Jie He Za Zhi"}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651326011607?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651326011607?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T22:27:01Z","timestamp":1793917621000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651326011607"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":43,"alternative-id":["S0147651326011607"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2026.120830","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Putative role of NF-\u03baB-mediated inflammation in acute cardiac injury induced by S-band microwave radiation in rats","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2026.120830","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"120830"}}