{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T15:28:48Z","timestamp":1793633328769,"version":"4.5.1"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:00:00Z","timestamp":1791158400000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32270910"],"award-info":[{"award-number":["32270910"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["24DX2800100"],"award-info":[{"award-number":["24DX2800100"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.ecoenv.2026.120902","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T14:22:22Z","timestamp":1791382942000},"page":"120902","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Diesel exhaust particles induce reproductive toxicity in mice via oxidative stress and ATP5\u03b11 S-sulfhydration inhibition"],"prefix":"10.1016","volume":"325","author":[{"given":"Mingjun","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayi","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minjie","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingying","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weihua","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.ecoenv.2026.120902_bib1","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1177\/0271678X231214826","article-title":"Diesel exhaust particles exposure exacerbates pro-thrombogenic plasma features ex-vivo after cerebral ischemia and accelerates tPA-induced clot-lysis in hypertensive subjects","volume":"44","author":"Arr\u00fae","year":"2024","journal-title":"J. Cereb. Blood Flow. Metab."},{"key":"10.1016\/j.ecoenv.2026.120902_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.147854","article-title":"Are standardized diesel exhaust particles (DEP) representative of ambient particles in air pollution toxicological studies?","volume":"788","author":"Farahani","year":"2021","journal-title":"Sci. Total. Environ."},{"key":"10.1016\/j.ecoenv.2026.120902_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.140887","article-title":"Atmospheric endocrine disruptors: A systematic review on oestrogenic and androgenic activity of particulate matter","volume":"349","author":"Gea","year":"2024","journal-title":"Chemosphere"},{"issue":"1","key":"10.1016\/j.ecoenv.2026.120902_bib4","doi-asserted-by":"crossref","first-page":"6222","DOI":"10.1038\/s41467-025-61582-8","article-title":"H2S-mediated protein S-sulfhydration modulates infectivity and autophagy in the rice blast fungus","volume":"16","author":"Hu","year":"2025","journal-title":"Nat. Commun."},{"issue":"17","key":"10.1016\/j.ecoenv.2026.120902_bib5","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.3390\/cells14171317","article-title":"Maternal Exposure to Diesel Exhaust Particles (DEPs) During Pregnancy and Adverse Pregnancy Outcomes: Focusing on the Effect of Particulate Matter on Trophoblast, Epithelial-Mesenchymal Transition","volume":"14","author":"Hur","year":"2025","journal-title":"Cells"},{"issue":"5","key":"10.1016\/j.ecoenv.2026.120902_bib6","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1093\/biolre\/ioae126","article-title":"Environmental toxins and reproductive health: unraveling the effects on Sertoli cells and the blood\u2013testis barrier in animals","volume":"111","author":"Jiang","year":"2024","journal-title":"Biol. Reprod."},{"issue":"20","key":"10.1016\/j.ecoenv.2026.120902_bib7","doi-asserted-by":"crossref","first-page":"4071","DOI":"10.1007\/s00018-019-03201-6","article-title":"Mechanisms regulating mammalian spermatogenesis and fertility recovery following germ cell depletion","volume":"76","author":"La","year":"2019","journal-title":"Cell. Mol. Life Sci."},{"issue":"2","key":"10.1016\/j.ecoenv.2026.120902_bib8","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3390\/biom11020291","article-title":"Determination of Genotoxicity Attributed to Diesel Exhaust Particles in Normal Human Embryonic Lung Cell (WI-38) Line","volume":"11","author":"Lee","year":"2021","journal-title":"Biomolecules"},{"key":"10.1016\/j.ecoenv.2026.120902_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2019.110053","article-title":"Automobile exhaust-derived PM2.5 induces blood-testis barrier damage through ROS-MAPK-Nrf2 pathway in sertoli cells of rats","volume":"189","author":"Liu","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2026.120902_bib10","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.ecoenv.2018.09.118","article-title":"Spermatogenesis dysfunction induced by PM2.5 from automobile exhaust via the ROS-mediated MAPK signaling pathway","volume":"167","author":"Liu","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2026.120902_bib11","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.jare.2025.06.038","article-title":"S-sulfhydration: Novel insights into the antioxidant and antiinflammation in age-related diseases","volume":"81","author":"Liu","year":"2026","journal-title":"J. Adv. Res."},{"issue":"4","key":"10.1016\/j.ecoenv.2026.120902_bib12","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"issue":"1","key":"10.1016\/j.ecoenv.2026.120902_bib13","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s12989-022-00450-5","article-title":"Controlled human exposure to diesel exhaust: results illuminate health effects of traffic-related air pollution and inform future directions","volume":"19","author":"Long","year":"2022","journal-title":"Part. Fibre Toxicol."},{"key":"10.1016\/j.ecoenv.2026.120902_bib14","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.jare.2024.05.033","article-title":"GYY4137-induced p65 sulfhydration protects synovial macrophages against pyroptosis by improving mitochondrial function in osteoarthritis development","volume":"71","author":"Ma","year":"2025","journal-title":"J. Adv. Res."},{"issue":"1","key":"10.1016\/j.ecoenv.2026.120902_bib15","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/s41467-025-66795-5","article-title":"Simultaneous and sensitive quantification of protein and low molecular weight persulfides, polysulfides and H2S in biological samples","volume":"17","author":"Miljkovic","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ecoenv.2026.120902_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2020.113400","article-title":"The new role of F1Fo ATP synthase in mitochondria-mediated neurodegeneration and neuroprotection","volume":"332","author":"Mnatsakanyan","year":"2020","journal-title":"Exp. Neurol."},{"issue":"Pt A","key":"10.1016\/j.ecoenv.2026.120902_bib17","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.phrs.2016.08.023","article-title":"S-Sulfhydration of ATP synthase by hydrogen sulfide stimulates mitochondrial bioenergetics","volume":"113","author":"M\u00f3dis","year":"2016","journal-title":"Pharmacol. Res."},{"issue":"1","key":"10.1016\/j.ecoenv.2026.120902_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1515\/bmc-2019-0001","article-title":"ATP synthase: structure, function and inhibition","volume":"10","author":"Neupane","year":"2019","journal-title":"Biomol. Concepts"},{"key":"10.1016\/j.ecoenv.2026.120902_bib19","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.scitotenv.2019.04.390","article-title":"Modulation of endocrine nuclear receptor activities by polyaromatic compounds present in fractionated extracts of diesel exhaust particles","volume":"677","author":"P\u011bn\u010d\u00edkov\u00e1","year":"2019","journal-title":"Sci. Total. Environ."},{"issue":"12","key":"10.1016\/j.ecoenv.2026.120902_bib20","doi-asserted-by":"crossref","first-page":"3175","DOI":"10.1007\/s10815-021-02314-x","article-title":"A novel posttranslational modification of histone, H3 S-sulfhydration, is down-regulated in asthenozoospermic sperm","volume":"38","author":"Qi","year":"2021","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.ecoenv.2026.120902_bib21","series-title":"Reactive Oxygen Species in Plants: The Right Balance","first-page":"93","article-title":"Generation and fate of ROS in mitochondria","author":"Sachdev","year":"2023"},{"key":"10.1016\/j.ecoenv.2026.120902_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.reprotox.2024.108682","article-title":"Whole-body exposure to filtered fraction of diesel exhaust induced localized testicular damage through attenuated functional response of glutathione-s-transferase in adult male Wistar rats","volume":"129","author":"Sarkar","year":"2024","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.ecoenv.2026.120902_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.etap.2025.104902","article-title":"Filtered diesel exhaust via whole body exposure disrupts male reproductive function through dysregulated endocrine axis and subdued testicular GSTs in juvenile Wistar rats","volume":"121","author":"Sarkar","year":"2026","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.ecoenv.2026.120902_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.113569","article-title":"Analysis by transcriptomics and metabolomics for the proliferation inhibition and dysfunction through redox imbalance-mediated DNA damage response and ferroptosis in male reproduction of mice and TM4 Sertoli cells exposed to PM2.5","volume":"238","author":"Shi","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2026.120902_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2024.114746","article-title":"Diesel exhaust particulate matter induces GC-1 spg cells oxidative stress by KEAP1-NRF2 pathway and inhibition of ATP5alpha1 S-sulfhydration","volume":"189","author":"Shi","year":"2024","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.ecoenv.2026.120902_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.molimm.2023.04.003","article-title":"Diesel exhaust exposure impairs recovery of lung epithelial and cellular damage in murine model","volume":"158","author":"Singh","year":"2023","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.ecoenv.2026.120902_bib27","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2024.1377090","article-title":"Role of hydrogen sulfide in the male reproductive system","volume":"15","author":"Song","year":"2024","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.ecoenv.2026.120902_bib28","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.bcp.2017.03.025","article-title":"H(2)S-induced S-sulfhydration of lactate dehydrogenase a (LDHA) stimulates cellular bioenergetics in HCT116 colon cancer cells","volume":"136","author":"Untereiner","year":"2017","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ecoenv.2026.120902_bib29","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.mce.2018.02.011","article-title":"Endogenous H2S resists mitochondria-mediated apoptosis in the adrenal glands via ATP5A1 S-sulfhydration in male mice","volume":"474","author":"Wang","year":"2018","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.ecoenv.2026.120902_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.micres.2023.127366","article-title":"The biological functions of protein S-sulfhydration in eukaryotes and the ever-increasing understanding of its effects on bacteria","volume":"271","author":"Wang","year":"2023","journal-title":"Microbiol. Res."},{"issue":"7","key":"10.1016\/j.ecoenv.2026.120902_bib31","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1161\/CIRCRESAHA.111.246124","article-title":"Redox regulation of mitochondrial ATP synthase: implications for cardiac resynchronization therapy","volume":"109","author":"Wang","year":"2011","journal-title":"Circ. Res."},{"issue":"18","key":"10.1016\/j.ecoenv.2026.120902_bib32","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.1089\/ars.2013.5604","article-title":"Sulfhydration of p66Shc at Cysteine59 mediates the antioxidant effect of hydrogen sulfide","volume":"21","author":"Xie","year":"2014","journal-title":"Antioxid. & Redox Signal."},{"key":"10.1016\/j.ecoenv.2026.120902_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.metop.2024.100276","article-title":"Hydrogen sulfide derived from apoptotic cells supports immune homeostasis","volume":"22","author":"Xu","year":"2024","journal-title":"Metabol. Open."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651326012327?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651326012327?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T14:52:44Z","timestamp":1793631164000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651326012327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":33,"alternative-id":["S0147651326012327"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2026.120902","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Diesel exhaust particles induce reproductive toxicity in mice via oxidative stress and ATP5\u03b11 S-sulfhydration inhibition","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2026.120902","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"120902"}}