{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T15:29:25Z","timestamp":1793633365321,"version":"4.5.1"},"reference-count":78,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002241","name":"Japan Science and Technology Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002241","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ecotoxicology and Environmental Safety"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.ecoenv.2026.120940","type":"journal-article","created":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T16:03:31Z","timestamp":1792253011000},"page":"120940","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Single cell ICP-MS reveals diversity in cadmium response across individual cells of three marine phytoplankton species"],"prefix":"10.1016","volume":"325","author":[{"given":"Yinghan","family":"Zai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6166-0462","authenticated-orcid":false,"given":"Kuo H.","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Kagaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asami S.","family":"Mashio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8210-4775","authenticated-orcid":false,"given":"Hiroshi","family":"Hasegawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ecoenv.2026.120940_bib1","doi-asserted-by":"crossref","DOI":"10.3390\/pr13092804","article-title":"Characterization of cadmium removal processes from seawater by the living biomass of three microalgae with different tolerance to this metal","volume":"13","author":"Abalde","year":"2025","journal-title":"Processes"},{"key":"10.1016\/j.ecoenv.2026.120940_bib2","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.biortech.2019.01.053","article-title":"Potential of acid-tolerant microalgae, Desmodesmus sp. MAS1 and Heterochlorella sp. MAS3, in heavy metal removal and biodiesel production at acidic pH","volume":"278","author":"Abinandan","year":"2019","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib3","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1023\/A:1003725626504","article-title":"Optimum production conditions for different high-quality marine algae","volume":"403","author":"Abu-Rezq","year":"1999","journal-title":"Hydrobiologia"},{"key":"10.1016\/j.ecoenv.2026.120940_bib4","doi-asserted-by":"crossref","DOI":"10.3390\/toxics9030042","article-title":"Heavy metals and pesticides toxicity in agricultural soil and plants: ecological risks and human health implications","volume":"9","author":"Alengebawy","year":"2021","journal-title":"Toxics"},{"key":"10.1016\/j.ecoenv.2026.120940_bib5","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/6730305","article-title":"Environmental chemistry and ecotoxicology of hazardous heavy metals: environmental persistence, toxicity, and bioaccumulation","author":"Ali","year":"2019","journal-title":"J. Chem."},{"key":"10.1016\/j.ecoenv.2026.120940_bib6","doi-asserted-by":"crossref","first-page":"17595","DOI":"10.1039\/D3RA00723E","article-title":"Heavy metal pollution in the aquatic environment: efficient and low-cost removal approaches to eliminate their toxicity: a review","volume":"13","author":"Aziz","year":"2023","journal-title":"RSC Adv."},{"key":"10.1016\/j.ecoenv.2026.120940_bib7","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/j.1529-8817.2007.00323.x","article-title":"Growth and toxicity of Prymnesium parvum (Haptophyta) as a function of salinity, light, and temperature","volume":"43","author":"Baker","year":"2007","journal-title":"J. Phycol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib8","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0022-0981(77)90085-5","article-title":"Survival of marine phytoplankton in high concentrations of heavy metals, and uptake of copper","volume":"26","author":"Bentley-Mowat","year":"1977","journal-title":"J. Exp. Mar. Bio. Ecol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib9","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/0022-0981(86)90205-4","article-title":"Reduction of marine phytoplankton reproduction rates by copper and cadmium","volume":"96","author":"Brand","year":"1986","journal-title":"J. Exp. Mar. Bio. Ecol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2020.e04691","article-title":"Heavy metal pollution in the environment and their toxicological effects on humans","volume":"6","author":"Briffa","year":"2020","journal-title":"Heliyon"},{"key":"10.1016\/j.ecoenv.2026.120940_bib11","doi-asserted-by":"crossref","DOI":"10.3389\/fmars.2021.656321","article-title":"Winter biogeochemical cycling of dissolved and particulate cadmium in the Indian Sector of the Southern Ocean (GEOTRACES GIpr07 Transect)","volume":"8","author":"Cloete","year":"2021","journal-title":"Front. Mar. Sci."},{"key":"10.1016\/j.ecoenv.2026.120940_bib12","doi-asserted-by":"crossref","DOI":"10.3390\/w15223962","article-title":"Study of Spirulina platensis (Arthrospira) Development under the Heavy Metals Influence, as a Potential Promoter of Wastewater Remediation","author":"Diaconu","year":"2023","journal-title":"Water"},{"key":"10.1016\/j.ecoenv.2026.120940_bib13","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1080\/09670260600937791","article-title":"Photosynthetic characteristics of the phytoplankton in the Scheldt estuary: community and single-cell fluorescence measurements","volume":"41","author":"Dijkman","year":"2006","journal-title":"Eur. J. Phycol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib14","article-title":"Using multiple endpoints to assess the toxicity of cadmium and cobalt for chlorophycean Raphidocelis subcapitata","volume":"208","author":"dos Reis","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2026.120940_bib15","doi-asserted-by":"crossref","first-page":"24753","DOI":"10.1007\/s11356-017-0330-6","article-title":"Distributions and sources of heavy metals in sediments of the Bohai Sea, China: a review","volume":"24","author":"Duan","year":"2017","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.ecoenv.2026.120940_bib16","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1002\/etc.1893","article-title":"Toxic thresholds of cadmium and lead to oceanic phytoplankton: Cell size and ocean basin-dependent effects","volume":"31","author":"Echeveste","year":"2012","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.ecoenv.2026.120940_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.149464","article-title":"Potential of three local marine microalgae from Tunisian coasts for cadmium, lead and chromium removals","volume":"799","author":"Elleuch","year":"2021","journal-title":"Sci. Total. Environ."},{"issue":"6","key":"10.1016\/j.ecoenv.2026.120940_bib18","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1016\/j.bone.2012.03.018","article-title":"Associations between dietary cadmium exposure and bone mineral density and risk of osteoporosis and fractures among women","volume":"50","author":"Engstr\u00f6m","year":"2012","journal-title":"Bone"},{"key":"10.1016\/j.ecoenv.2026.120940_bib19","first-page":"1","article-title":"Toxicity, physiological response, and biosorption mechanism of Dunaliella salina to copper, lead, and cadmium","volume":"15","author":"Gao","year":"2024","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib20","article-title":"Capabilities of single cell ICP-MS for the analysis of cell suspensions from solid tissues","volume":"13","author":"Garc\u00eda","year":"2022","journal-title":"Nanomaterials"},{"key":"10.1016\/j.ecoenv.2026.120940_bib21","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph17113782","article-title":"The effects of cadmium toxicity","volume":"17","author":"Genchi","year":"2020","journal-title":"Int. J. Environ. Res. Public. Health"},{"key":"10.1016\/j.ecoenv.2026.120940_bib22","unstructured":"Group, G.I.D.P., 2025. The GEOTRACES Intermediate Data Product 2025 (IDP2025). https:\/\/doi.org\/doi:10.5285\/42c92148-8d03-8be6-e063-7086abc09f0c."},{"key":"10.1016\/j.ecoenv.2026.120940_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.126336","article-title":"Biosorption of heavy metal ions by green alga Neochloris oleoabundans: Effects of metal ion properties and cell wall structure","volume":"418","author":"Gu","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2026.120940_bib24","doi-asserted-by":"crossref","first-page":"6150","DOI":"10.1007\/s11356-013-1668-z","article-title":"Assessing heavy metal pollution in the surface soils of a region that had undergone three decades of intense industrialization and urbanization","volume":"20","author":"Hu","year":"2013","journal-title":"Environ. Sci. Pollut. Res."},{"issue":"3","key":"10.1016\/j.ecoenv.2026.120940_bib25","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1016\/j.jhazmat.2011.07.019","article-title":"Biosorption of heavy metal ions from aqueous solution by red macroalgae","volume":"192","author":"Ibrahim","year":"2011","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2026.120940_bib26","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s00249-019-01347-6","article-title":"Algal cell response to laboratory-induced cadmium stress: a multimethod approach","volume":"48","author":"Ivo\u0161evi\u0107 DeNardis","year":"2019","journal-title":"Eur. Biophys. J."},{"key":"10.1016\/j.ecoenv.2026.120940_bib27","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1080\/09670260903118214","article-title":"Flow cytometric analysis of the cadmium-exposed green alga Chlamydomonas reinhardtii (chlorophyceae","volume":"44","author":"Jamers","year":"2009","journal-title":"Eur. J. Phycol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib28","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.chemosphere.2018.12.033","article-title":"Cadmium bioaccumulation and elimination in tissues of the freshwater mussel Anodonta woodiana","volume":"219","author":"Jing","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2026.120940_bib29","doi-asserted-by":"crossref","first-page":"13772","DOI":"10.1007\/s11356-015-4881-0","article-title":"The uptake and bioaccumulation of heavy metals by food plants, their effects on plants nutrients, and associated health risk: a review","volume":"22","author":"Khan","year":"2015","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.ecoenv.2026.120940_bib30","doi-asserted-by":"crossref","DOI":"10.3390\/microorganisms8010115","article-title":"Probing the role of the chloroplasts in heavy metal tolerance and accumulation in Euglena gracilis","volume":"8","author":"Khatiwada","year":"2020","journal-title":"Microorganisms"},{"key":"10.1016\/j.ecoenv.2026.120940_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2020.123068","article-title":"Diatom mediated heavy metal remediation: A review","volume":"305","author":"Kiran Marella","year":"2020","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib32","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/s11099-009-0071-y","article-title":"Responses of the Antarctic microalga Koliella antarctica (Trebouxiophyceae, Chlorophyta) to cadmium contamination","volume":"47","author":"la Rocca","year":"2009","journal-title":"Photosynthetica"},{"key":"10.1016\/j.ecoenv.2026.120940_bib33","article-title":"Macroalgae metal-biomonitoring in Antarctica: Addressing the consequences of human presence in the white continent","author":"Lavergne","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2026.120940_bib34","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.aquatox.2008.12.007","article-title":"Cadmium detoxification strategies in two phytoplankton species: Metal binding by newly synthesized thiolated peptides and metal sequestration in granules","volume":"92","author":"Lavoie","year":"2009","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib35","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0003-9365(11)80268-X","article-title":"The Flagellar Apparatus in the Marine Flagellate Algal Genus Oltmannsiellopsis (Dunaliellales, Chlorophyceae)","volume":"143","author":"Lokhorst","year":"1993","journal-title":"Arch. F. \u00fcR. Protistenkd."},{"key":"10.1016\/j.ecoenv.2026.120940_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.111715","article-title":"How marine diatoms cope with metal challenge: Insights from the morphotype-dependent metal tolerance in Phaeodactylum tricornutum","volume":"208","author":"Ma","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2026.120940_bib37","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.ecoenv.2014.12.031","article-title":"Effects of mine wastewater irrigation on activities of soil enzymes and physiological properties, heavy metal uptake and grain yield in winter wheat","volume":"113","author":"Ma","year":"2015","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2026.120940_bib38","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1002\/jobm.202100363","article-title":"Emerging role of microalgae in heavy metal bioremediation","volume":"62","author":"Manikandan","year":"2021","journal-title":"J. Basic. Microbiol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib39","article-title":"Environmental assessment of soils and crops based on heavy metal risk analysis in Southeastern China","author":"Mao","year":"2023","journal-title":"Agronomy"},{"key":"10.1016\/j.ecoenv.2026.120940_bib40","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0168-1656(99)00055-3","article-title":"Screening of marine microalgae for bioremediation of cadmium-polluted seawater","volume":"70","author":"Matsunaga","year":"1999","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib41","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1007\/s00244-005-0207-4","article-title":"Simultaneous Cd2+, Zn2+, and Pb2+ uptake and accumulation by photosynthetic Euglena gracilis","volume":"51","author":"Mendoza-C\u00f3zatl","year":"2006","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib42","doi-asserted-by":"crossref","first-page":"2603","DOI":"10.1897\/05-009R.1","article-title":"Comparison of Cd, Cu, and Zn toxic effects on four marine phytoplankton by pulse-amplitude-modulated fluorometry","volume":"24","author":"Miao","year":"2005","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.ecoenv.2026.120940_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.marchem.2021.104063","article-title":"Basin scale distributions of dissolved manganese, nickel, zinc and cadmium in the Mediterranean Sea","volume":"238","author":"Middag","year":"2022","journal-title":"Mar. Chem."},{"key":"10.1016\/j.ecoenv.2026.120940_bib44","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1080\/09670262.2020.1758347","article-title":"Physiological and morphological response of marine diatom Cylindrotheca closterium (Bacillariophyceae) exposed to Cadmium","volume":"56","author":"Mi\u0161i\u0107 Radi\u0107","year":"2021","journal-title":"Eur. J. Phycol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.126450","article-title":"Assessment of industrial wastewater for potentially toxic elements, human health (dermal) risks, and pollution sources: A case study of Gadoon Amazai industrial estate, Swabi, Pakistan","volume":"419","author":"Muhammad","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.ecoenv.2026.120940_bib46","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S1470-2045(06)70545-9","article-title":"Environmental exposure to cadmium and risk of cancer: A prospective population-based study","volume":"7","author":"Nawrot","year":"2006","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib47","doi-asserted-by":"crossref","first-page":"2762","DOI":"10.1002\/etc.2362","article-title":"Photosynthetic and cellular toxicity of cadmium in Chlorella vulgaris","volume":"32","author":"Ou-Yang","year":"2013","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.ecoenv.2026.120940_bib48","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1007\/s10811-020-02092-6","article-title":"Ecophysiology of a successful phytoplankton competitor in the African flamingo lakes: the green alga Picocystis salinarum (Picocystophyceae)","volume":"32","author":"P\u00e1lmai","year":"2020","journal-title":"J. Appl. Phycol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib49","article-title":"Arsenic biotransformation potential of marine phytoplankton under a salinity gradient","volume":"47","author":"Papry","year":"2020","journal-title":"Algal Res. Biofuels Bioprod."},{"key":"10.1016\/j.ecoenv.2026.120940_bib50","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1111\/pce.13674","article-title":"Pyrenoidal sequestration of cadmium impairs carbon dioxide fixation in a microalga","volume":"43","author":"Penen","year":"2020","journal-title":"Plant. Cell. Environ."},{"key":"10.1016\/j.ecoenv.2026.120940_bib51","unstructured":"PerkinElmer Inc, 2000. NexION \u00ae 2000 ICP Mass Spectrometer ANY MATRIX ANY INTERFERENCE ANY PARTICLE SIZE."},{"key":"10.1016\/j.ecoenv.2026.120940_bib52","doi-asserted-by":"crossref","DOI":"10.3390\/w14203335","article-title":"Active biomonitoring of heavy metal concentrations in aquatic environment using mosses and algae","author":"Respondek","year":"2022","journal-title":"Water"},{"key":"10.1016\/j.ecoenv.2026.120940_bib53","series-title":"Green Chemistry","first-page":"359","article-title":"Heavy Metal Pollution and Remediation","author":"RoyChowdhury","year":"2018"},{"key":"10.1016\/j.ecoenv.2026.120940_bib54","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2026811118","article-title":"Single-cell visualization and quantification of trace metals in Chlamydomonas lysosome-related organelles","volume":"118","author":"Schmollinger","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ecoenv.2026.120940_bib55","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10661-021-08848-y","article-title":"Assessment of heavy metal pollution in the agricultural soils, plants, and in the atmospheric particulate matter of a suburban industrial region in Dhaka, Bangladesh","volume":"193","author":"Shammi","year":"2021","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.ecoenv.2026.120940_bib56","doi-asserted-by":"crossref","first-page":"5531","DOI":"10.1007\/s00216-019-01933-9","article-title":"Evaluating the treatment effectiveness of copper-based algaecides on toxic algae Microcystis aeruginosa using single cell-inductively coupled plasma-mass spectrometry","volume":"411","author":"Shen","year":"2019","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.ecoenv.2026.120940_bib57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1029\/2022GB007441","article-title":"Biological, Physical, and Atmospheric Controls on the Distribution of Cadmium and Its Isotopes in the Pacific Ocean","volume":"37","author":"Sieber","year":"2023","journal-title":"Glob. Biogeochem. Cycles"},{"key":"10.1016\/j.ecoenv.2026.120940_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2023.106499","article-title":"Evaluation of Cd2+ stress on Synechocystis sp. PCC6803 based on single-cell elemental accumulation and algal toxicological response","volume":"258","author":"Tao","year":"2023","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib59","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1093\/plphys\/kiab375","article-title":"Long-term acclimation to cadmium exposure reveals extensive phenotypic plasticity in Chlamydomonas","volume":"187","author":"Thiriet-Rupert","year":"2021","journal-title":"Plant. Physiol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.131196","article-title":"Elucidating the bioremediation mechanism of Scenedesmus sp. IITRIND2 under cadmium stress","volume":"283","author":"Tripathi","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2026.120940_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.117443","article-title":"Heavy metal detoxification mechanisms by microalgae: Insights from transcriptomics analysis","volume":"285","author":"Tripathi","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.ecoenv.2026.120940_bib62","doi-asserted-by":"crossref","first-page":"3806","DOI":"10.1021\/ac034227z","article-title":"Quantifying trace elements in individual aquatic protist cells with a synchrotron X-ray fluorescence microprobe","volume":"75","author":"Twining","year":"2003","journal-title":"Anal. Chem."},{"key":"10.1016\/j.ecoenv.2026.120940_bib63","doi-asserted-by":"crossref","DOI":"10.1897\/06-518R.1","article-title":"Cadmium accumulation in herbivorous and carnivorous small mammals: Meta-analysis of field data and validation of the bioaccumulation model optimal modeling for ecotoxicological applications","volume":"26","author":"Veltman","year":"2007","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.ecoenv.2026.120940_bib64","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1134\/S0006350924700489","article-title":"Acclimation of primary photosynthetic reactions in the cells of Chlamydomonas reinhardtii to cadmium: analysis of cell population heterogeneity","volume":"69","author":"Volgusheva","year":"2024","journal-title":"Biophysics"},{"key":"10.1016\/j.ecoenv.2026.120940_bib65","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.aquatox.2009.08.006","article-title":"Cadmium in three marine phytoplankton: Accumulation, subcellular fate and thiol induction","volume":"95","author":"Wang","year":"2009","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib66","doi-asserted-by":"crossref","DOI":"10.3390\/toxics10080455","article-title":"Cadmium caused different toxicity to Photosystem I and Photosystem II of Freshwater Unicellular Algae Chlorella pyrenoidosa (Chlorophyta)","volume":"10","author":"Wang","year":"2022","journal-title":"Toxics"},{"key":"10.1016\/j.ecoenv.2026.120940_bib67","doi-asserted-by":"crossref","DOI":"10.1093\/plankt\/fbab054","article-title":"Phytoplankton growth at low temperatures: results from low temperature incubations","author":"Wang","year":"2021","journal-title":"J. Plankton Res."},{"key":"10.1016\/j.ecoenv.2026.120940_bib68","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1093\/aje\/kwp248","article-title":"Blood cadmium and lead and chronic kidney disease in US sdults: a joint analysis","volume":"170","author":"Weaver","year":"2009","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib69","first-page":"1","article-title":"Quantitative relationship between cadmium uptake and the kinetics of phytochelatin induction by cadmium in a marine diatom","volume":"6","author":"Wu","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ecoenv.2026.120940_bib70","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.aquatox.2018.12.008","article-title":"Predicting cadmium toxicity with the kinetics of phytochelatin induction in a marine diatom","volume":"207","author":"Wu","year":"2019","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib71","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1007\/s00343-012-1111-1","article-title":"Molecular identification and culture trials of Eutreptiella gymnastica (Eutreptiales, Euglenophyceae)","volume":"30","author":"Xu","year":"2012","journal-title":"Chin. J. Oceanol. Limnol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib72","article-title":"Microalgal bioremediation of heavy metal pollution in water: Recent advances, challenges, and prospects","volume":"286","author":"Yan","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.ecoenv.2026.120940_bib73","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105239","article-title":"An integrated analysis on source-exposure risk of heavy metals in agricultural soils near intense electronic waste recycling activities","volume":"133","author":"Yang","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.ecoenv.2026.120940_bib74","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.ecoenv.2015.11.043","article-title":"Effect of cadmium-polluted diet on growth, salinity stress, hepatotoxicity of juvenile Pacific white shrimp (Litopenaeus vannamei): Protective effect of Zn(II)\u2212curcumin","volume":"125","author":"Yu","year":"2016","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.ecoenv.2026.120940_bib75","doi-asserted-by":"crossref","DOI":"10.1016\/j.marpolbul.2019.110717","article-title":"Bioaccumulation and health risk assessment of heavy metals to bivalve species in Daya Bay (South China Sea): Consumption advisory","volume":"150","author":"Yuan","year":"2020","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.ecoenv.2026.120940_bib76","doi-asserted-by":"crossref","DOI":"10.1016\/j.sab.2023.106801","article-title":"Development of a new detection method for cadmium in marine phytoplankton based on single cell inductively coupled plasma mass spectrometry","volume":"209","author":"Zai","year":"2023","journal-title":"Spectrochim. Acta - Part. B At. Spectrosc."},{"key":"10.1016\/j.ecoenv.2026.120940_bib77","doi-asserted-by":"crossref","DOI":"10.1128\/aem.00228-23","article-title":"Metabolic plasticity endows mixotrophic organisms with high tolerance to cadmium and special potential for recovering cadmium-contaminated aquatic environment","volume":"89","author":"Zhang","year":"2023","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.ecoenv.2026.120940_bib78","doi-asserted-by":"crossref","first-page":"27367","DOI":"10.1021\/acs.est.5c11233","article-title":"Unlocking phytoplankton metallomes with comparative analysis of metal quotas, quantitative proteomics, and inferred metalloproteomes","volume":"59","author":"Zhang","year":"2025","journal-title":"Environ. Sci. Technol."}],"container-title":["Ecotoxicology and Environmental Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651326012704?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147651326012704?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T14:58:41Z","timestamp":1793631521000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147651326012704"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":78,"alternative-id":["S0147651326012704"],"URL":"https:\/\/doi.org\/10.1016\/j.ecoenv.2026.120940","relation":{},"ISSN":["0147-6513"],"issn-type":[{"value":"0147-6513","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Single cell ICP-MS reveals diversity in cadmium response across individual cells of three marine phytoplankton species","name":"articletitle","label":"Article Title"},{"value":"Ecotoxicology and Environmental Safety","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ecoenv.2026.120940","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"120940"}}