{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:49:15Z","timestamp":1782175755648,"version":"3.54.5"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,1,29]],"date-time":"2016-01-29T00:00:00Z","timestamp":1454025600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Egyptian Heart Journal"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1016\/j.ehj.2016.05.001","type":"journal-article","created":{"date-parts":[[2016,5,20]],"date-time":"2016-05-20T17:40:09Z","timestamp":1463766009000},"page":"45-54","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Predictors of intravenous amiodarone induced liver injury"],"prefix":"10.1186","volume":"69","author":[{"given":"O.A.","family":"Diab","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Kamel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed Adel","family":"Abd-Elhamid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"10.1016\/j.ehj.2016.05.001_b0005","first-page":"686","article-title":"Acute hepatitis complicating intravenous amiodarone treatment","volume":"3","author":"Agozzino","year":"2002","journal-title":"Ital Heart J"},{"key":"10.1016\/j.ehj.2016.05.001_b0010","doi-asserted-by":"crossref","first-page":"96","DOI":"10.5414\/CPP46096","article-title":"Fatal amiodarone-induced hepatotoxicity: a case report and literature review","volume":"46","author":"Chan","year":"2008","journal-title":"Int J Clin Pharmacol Ther"},{"key":"10.1016\/j.ehj.2016.05.001_b0015","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/01.CCM.0000151048.72393.44","article-title":"Hepatotoxicity during rapid intravenous loading with amiodarone: description of three cases and review of the literature","volume":"33","author":"R\u00e4tz Bravo","year":"2005","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ehj.2016.05.001_b0020","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s00228-011-1126-0","article-title":"Amiodarone-induced acute hepatotoxicity","volume":"68","author":"Rao","year":"2012","journal-title":"Eur J Clin Pharmacol"},{"key":"10.1016\/j.ehj.2016.05.001_b0025","first-page":"748","article-title":"Acute amiodarone liver toxicity likely due to ischemic hepatitis","volume":"13","author":"Gluck","year":"2011","journal-title":"Isr Med Assoc J"},{"key":"10.1016\/j.ehj.2016.05.001_b0030","doi-asserted-by":"crossref","first-page":"196","DOI":"10.4254\/wjh.v4.i6.196","article-title":"Acute hepatitis secondary to parenteral amiodarone does not preclude subsequent oral therapy","volume":"4","author":"Lahbabi","year":"2012","journal-title":"World J Hepatol"},{"key":"10.1016\/j.ehj.2016.05.001_b0035","doi-asserted-by":"crossref","first-page":"191","DOI":"10.2147\/DHPS.S48640","article-title":"Hyperacute drug-induced hepatitis with intravenous amiodarone: case report and review of the literature","volume":"5","author":"Nasser","year":"2013","journal-title":"Drug Healthc Patient Saf"},{"key":"10.1016\/j.ehj.2016.05.001_b0040","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1053\/j.jvca.2012.02.002","article-title":"CASE 6\u20132012: suspected amiodarone hepatotoxicity after cardiac surgery","volume":"26","author":"Thiele","year":"2012","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10.1016\/j.ehj.2016.05.001_b0045","first-page":"189","article-title":"Hepatotoxicity after continuous amiodarone infusion in a postoperative cardiac infant","volume":"17","author":"Kicker","year":"2012","journal-title":"J Pediatr Pharmacol Ther"},{"key":"10.1016\/j.ehj.2016.05.001_b0050","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2012-007080","article-title":"Acute hepatic failure following intravenous amiodarone","author":"Grecian","year":"2012","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.ehj.2016.05.001_b0055","doi-asserted-by":"crossref","first-page":"e62-4","DOI":"10.1097\/TP.0b013e3182115bc1","article-title":"Acute amiodarone hepatotoxicity after liver transplantation","volume":"91","author":"von Vital","year":"2011","journal-title":"Transplantation"},{"key":"10.1016\/j.ehj.2016.05.001_b0060","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.ajem.2010.03.035","article-title":"Acute liver injury after intravenous amiodarone: a case report","volume":"29","author":"Verhovez","year":"2011","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ehj.2016.05.001_b0065","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1007\/BF03324889","article-title":"Hepatotoxicity after intravenous amiodarone","volume":"20","author":"Cataldi","year":"2008","journal-title":"Aging Clin Exp Res"},{"key":"10.1016\/j.ehj.2016.05.001_b0070","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1016\/j.ajem.2007.02.045","article-title":"Acute toxic hepatitis after amiodarone intravenous loading","volume":"25","author":"Rizzioli","year":"2007","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ehj.2016.05.001_b0075","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1097\/01.BCR.0000169896.23823.C7","article-title":"Rapid acute amiodarone-induced hepatotoxicity in a burn patient","volume":"26","author":"Maker","year":"2005","journal-title":"J Burn Care Rehabil"},{"key":"10.1016\/j.ehj.2016.05.001_b0080","first-page":"233","article-title":"Severe acute hepatitis following intravenous amiodarone: a case report and review of the literature","volume":"78","author":"Stratton","year":"2015","journal-title":"Acta Gastroenterol Belg"},{"key":"10.1016\/j.ehj.2016.05.001_b0085","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/S0002-9343(02)01149-X","article-title":"Acute hepatitis induced by parenteral amiodarone","volume":"113","author":"Gregory","year":"2002","journal-title":"Am J Med"},{"key":"10.1016\/j.ehj.2016.05.001_b0090","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1136\/hrt.59.6.690","article-title":"Acute hepatitis after parenteral amiodarone administration","volume":"59","author":"Pye","year":"1988","journal-title":"Br Heart J"},{"key":"10.1016\/j.ehj.2016.05.001_b0095","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1136\/gut.34.4.565","article-title":"Early acute hepatitis with parenteral amiodarone: a toxic effect of the vehicle?","volume":"34","author":"Rhodes","year":"1993","journal-title":"Gut"},{"key":"10.1016\/j.ehj.2016.05.001_b0100","doi-asserted-by":"crossref","first-page":"756","DOI":"10.3390\/s6070756","article-title":"Aspartate aminotransferase (AST\/GOT) and alanine aminotransferase (ALT\/GPT) detection techniques","volume":"6","author":"Huang","year":"2006","journal-title":"Sensors (Basel)"},{"key":"10.1016\/j.ehj.2016.05.001_b0105","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1001\/jama.283.1.74","article-title":"Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection","volume":"283","author":"Sulkowski","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.ehj.2016.05.001_b0110","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/j.1552-4604.1995.tb04072.x","article-title":"Risk factors for the development of specific noncardiovascular adverse effects associated with amiodarone","volume":"35","author":"Tisdale","year":"1995","journal-title":"J Clin Pharmacol"},{"key":"10.1016\/j.ehj.2016.05.001_b0115","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1177\/147323000903700631","article-title":"Clinical applications and acute hepatotoxicity of intravenous amiodarone","volume":"37","author":"Huang","year":"2009","journal-title":"J Intern Med Res"},{"key":"10.1016\/j.ehj.2016.05.001_b0120","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1002\/hep.1840090504","article-title":"Amiodarone hepatotoxicity: prevalence and clinicopathologic correlations among 104 patients","volume":"9","author":"Lewis","year":"1989","journal-title":"Hepatology"},{"key":"10.1016\/j.ehj.2016.05.001_b0125","doi-asserted-by":"crossref","first-page":"2360","DOI":"10.1016\/j.cgh.2015.06.020","article-title":"Risk of acute liver failure in patients with drug-induced liver injury: evaluation of Hy\u2019s law and a new prognostic model","volume":"13","author":"Lo Re","year":"2015","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.ehj.2016.05.001_b0130","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/S1665-2681(19)30910-X","article-title":"Bilirubin alone as a biomarker for short-term mortality in acute-on-chronic liver failure: an important prognostic indicator","volume":"13","author":"L\u00f3pez-Vel\u00e1zquez","year":"2013","journal-title":"Ann Hepatol"}],"container-title":["The Egyptian Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1110260816300084?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1110260816300084?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,8]],"date-time":"2019-09-08T01:34:59Z","timestamp":1567906499000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1110260816300084"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["S1110260816300084"],"URL":"https:\/\/doi.org\/10.1016\/j.ehj.2016.05.001","relation":{},"ISSN":["1110-2608"],"issn-type":[{"value":"1110-2608","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Predictors of intravenous amiodarone induced liver injury","name":"articletitle","label":"Article Title"},{"value":"The Egyptian Heart Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ehj.2016.05.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Egyptian Society of Cardiology. Production and hosting by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}