{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T19:34:05Z","timestamp":1761766445796,"version":"build-2065373602"},"reference-count":18,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Gerencia Regional de Salud, Consejer\u00eda de Sanidad, Junta de Castilla y Le\u00f3n","award":["GRS 1213\/A\/15"],"award-info":[{"award-number":["GRS 1213\/A\/15"]}]}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Enfermedades Infecciosas y Microbiolog\u00eda Cl\u00ednica"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.eimc.2018.06.017","type":"journal-article","created":{"date-parts":[[2018,9,17]],"date-time":"2018-09-17T19:15:14Z","timestamp":1537211714000},"page":"244-250","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Summation of peaks and L34 ribosomal protein in the presence and absence of antibiotics enables susceptibility testing using MALDI-TOF mass spectrometry in 2 h from Escherichia coli-positive blood cultures"],"prefix":"10.1016","volume":"37","author":[{"given":"Sara","family":"Hern\u00e1ndez Egido","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana de","family":"Luis Reboredo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alicia","family":"Garc\u00eda Se\u00f1\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Bel\u00e9n","family":"Gil Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Luis","family":"Mu\u00f1oz Bellido","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Manual","family":"Gonz\u00e1lez Buitrago","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"S\u00e1nchez-Juanes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.eimc.2018.06.017_bib0095","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1086\/600885","article-title":"Ongoing revolution in bacteriology: routine identification of bacteria by matrix-assisted laser desorption ionization time-of-flight mass spectrometry","volume":"49","author":"Seng","year":"2009","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.eimc.2018.06.017_bib0100","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1002\/mas.10004","article-title":"Characterization of intact microorganisms by MALDI mass spectrometry","volume":"20","author":"Fenselau","year":"2001","journal-title":"Mass Spectrom Rev"},{"key":"10.1016\/j.eimc.2018.06.017_bib0105","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.eimc.2015.02.016","article-title":"MALDI-TOD mass spectrometry in clinical microbiology. Current situation and future perspectives","volume":"33","author":"Mu\u00f1oz Bellido","year":"2015","journal-title":"Enferm Infecc Microbiol Clin"},{"key":"10.1016\/j.eimc.2018.06.017_bib0110","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.eimc.2009.12.009","article-title":"Identifying bacteria using a matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometer. Comparison with routine methods used in clinical microbiology laboratories","volume":"28","author":"Ferreira","year":"2010","journal-title":"Enferm Infecc Microbiol Clin"},{"key":"10.1016\/j.eimc.2018.06.017_bib0115","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1128\/JCM.01541-09","article-title":"Rapid identification of bacteria in positive blood culture broths by MALDI-TOF MS","volume":"48","author":"Stevenson","year":"2010","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.eimc.2018.06.017_bib0120","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/j.1469-0691.2010.03257.x","article-title":"Microorganisms direct identification from blood culture by MALDI-TOF mass spectrometry","volume":"17","author":"Ferreira","year":"2011","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.eimc.2018.06.017_bib0125","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1128\/JCM.02215-09","article-title":"Direct identification of urinary tract pathogens from urine samples by MALDI-TOF mass spectrometry","volume":"48","author":"Ferreira","year":"2010","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.eimc.2018.06.017_bib0130","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.diagmicrobio.2016.10.016","article-title":"Imipenem-avibactam: a novel combination for the rapid detection of carbapenemase activity in Enterobacteriaceae and Acinetobacter baumannii by MALDI-TOF mass spectrometry","volume":"87","author":"Ovia\u00f1o","year":"2017","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.eimc.2018.06.017_bib0135","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1093\/jac\/dkx127","article-title":"Rapid direct detection of carbapenemase-producing Enterobacteriaceae in clinical urine samples by MALDI-TOF MS analysis","volume":"72","author":"Ovia\u00f1o","year":"2017","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.eimc.2018.06.017_bib0140","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.diagmicrobio.2013.06.001","article-title":"Non-phenotypic tests to detect and characterize antibiotic resistance mechanisms in Enterobacteriaceae","volume":"77","author":"Lupo","year":"2013","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.eimc.2018.06.017_bib0145","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1093\/jac\/dkx218","article-title":"Rapid detection of the plasmid-mediated quinolone resistance determinant AAC(6\u2032)-Ib-cr in Enterobacteriaceae by MALDI-TOF MS analysis","volume":"72","author":"Ovia\u00f1o","year":"2017","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.eimc.2018.06.017_bib0150","doi-asserted-by":"crossref","first-page":"3741","DOI":"10.1128\/JCM.01536-13","article-title":"MALDI biotyper-based rapid resistance detection by stable-isotope labeling","volume":"51","author":"Sparbier","year":"2013","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.eimc.2018.06.017_bib0155","doi-asserted-by":"crossref","first-page":"4155","DOI":"10.1128\/JCM.01872-14","article-title":"Quantitative MALDI-TOF MS for rapid resistance detection","volume":"52","author":"Lange","year":"2014","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.eimc.2018.06.017_bib0160","doi-asserted-by":"crossref","first-page":"2820","DOI":"10.1128\/JCM.01131-16","article-title":"Evaluation of a semiquantitative matrix-assisted laser desorption ionization-time of flight mass spectrometry method for rapid antimicrobial susceptibility testing of positive blood cultures","volume":"54","author":"Jung","year":"2016","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.eimc.2018.06.017_bib0165","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.ymeth.2016.01.008","article-title":"MBT-ASTRA: a suitable tool for fast antibiotic susceptibility testing?","volume":"104","author":"Sparbier","year":"2016","journal-title":"Methods"},{"year":"2017","series-title":"Performance standards for antimicrobial susceptibility testing. CLSI supplement M-100","author":"CLSI","key":"10.1016\/j.eimc.2018.06.017_bib0170"},{"key":"10.1016\/j.eimc.2018.06.017_bib0175","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1128\/JCM.02089-16","article-title":"Matrix-assisted laser desorption ionization-time of flight mass spectrometry for combined species identification and drug sensitivity testing in mycobacteria","volume":"55","author":"Ceyssens","year":"2017","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.eimc.2018.06.017_bib0180","doi-asserted-by":"crossref","first-page":"e0164260","DOI":"10.1371\/journal.pone.0164260","article-title":"The technical and biological reproducibility of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) based typing: employment of bioinformatics in a multicenter study","volume":"11","author":"Oberle","year":"2016","journal-title":"PLoS One"}],"container-title":["Enfermedades Infecciosas y Microbiolog\u00eda Cl\u00ednica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0213005X18302301?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0213005X18302301?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T13:04:52Z","timestamp":1759323892000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0213005X18302301"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["S0213005X18302301"],"URL":"https:\/\/doi.org\/10.1016\/j.eimc.2018.06.017","relation":{},"ISSN":["0213-005X"],"issn-type":[{"type":"print","value":"0213-005X"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Summation of peaks and L34 ribosomal protein in the presence and absence of antibiotics enables susceptibility testing using MALDI-TOF mass spectrometry in 2h from Escherichia coli-positive blood cultures","name":"articletitle","label":"Article Title"},{"value":"Enfermedades Infecciosas y Microbiolog\u00eda Cl\u00ednica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eimc.2018.06.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Espa\u00f1a, S.L.U. and Sociedad Espa\u00f1ola de Enfermedades Infecciosas y Microbiolog\u00eda Cl\u00ednica. All rights reserved.","name":"copyright","label":"Copyright"}]}}