{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T05:45:49Z","timestamp":1772948749213,"version":"3.50.1"},"reference-count":30,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Enfermedades infecciosas y microbiologia clinica (English ed.)"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.eimce.2026.503052","type":"journal-article","created":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T19:22:43Z","timestamp":1771356163000},"page":"503052","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Liver abscesses: Clinical-epidemiological, microbiological characteristics and mortality predictors"],"prefix":"10.1016","volume":"44","author":[{"given":"Daniel","family":"Robles de la Osa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"S\u00e1nchez del Hoyo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"P\u00e9rez Urra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lidia","family":"Herv\u00e9s Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Espinel Pinedo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen Beatriz","family":"Bulnes Labrador","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"L\u00f3pez All\u00fae","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Gonz\u00e1lez de Castro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1ngela Martina","family":"Montero Moret\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Santos Santamarta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"P\u00e9rez Citores","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Santos Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Maestro Antol\u00edn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno Antonio","family":"Moreira da Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Barcenilla Laguna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Cimavilla Rom\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Jos\u00e9","family":"Rancel Medina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Antonella","family":"Rizzo Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00f3nica","family":"Bru Arca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeisson Andrey","family":"Toro Santib\u00e1\u00f1ez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Germ\u00e1n","family":"P\u00e9rez Mill\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.eimce.2026.503052_bib0005","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1097\/00000658-199605000-00016","article-title":"Pyogenic hepatic abscess. Changing trends over 42 years","volume":"223","author":"Huang","year":"1996","journal-title":"Ann Surg"},{"issue":"9","key":"10.1016\/j.eimce.2026.503052_bib0010","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1086\/513201","article-title":"Diabetes mellitus and pyogenic liver abscess: risk and prognosis","volume":"44","author":"Thomsen","year":"2007","journal-title":"Clin Infect Dis"},{"issue":"8","key":"10.1016\/j.eimce.2026.503052_bib0015","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1007\/s00228-017-2256-9","article-title":"Correlation between proton pump inhibitors and risk of pyogenic liver abscess","volume":"73","author":"Lin","year":"2017","journal-title":"Eur J Clin Pharmacol"},{"issue":"4","key":"10.1016\/j.eimce.2026.503052_bib0020","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1148\/rg.2016150196","article-title":"Multimodality imaging of liver infections: differential diagnosis and potential pitfalls","volume":"36","author":"B\u00e4chler","year":"2016","journal-title":"Radiographics"},{"issue":"37","key":"10.1016\/j.eimce.2026.503052_bib0025","doi-asserted-by":"crossref","first-page":"e8050","DOI":"10.1097\/MD.0000000000008050","article-title":"Clinical and microbiological characteristics of pyogenic liver abscess in a tertiary hospital in East China","volume":"96","author":"Kong","year":"2017","journal-title":"Medicine (Baltimore)"},{"issue":"1","key":"10.1016\/j.eimce.2026.503052_bib0030","doi-asserted-by":"crossref","first-page":"8","DOI":"10.4103\/tjem.tjem_198_23","volume":"24","author":"Islam","year":"2024","journal-title":"Turkish J Emerg Med"},{"issue":"5","key":"10.1016\/j.eimce.2026.503052_bib0035","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.jinf.2019.02.006","article-title":"The utility of peripheral blood leucocyte ratios as biomarkers in infectious diseases: a systematic review and meta-analysis","volume":"78","author":"Russell","year":"2019","journal-title":"J Infect"},{"issue":"3","key":"10.1016\/j.eimce.2026.503052_bib0040","doi-asserted-by":"crossref","first-page":"E86","DOI":"10.1111\/ans.16461","article-title":"Prospective randomized comparative study of percutaneous catheter drainage and percutaneous needle aspiration in the treatment of liver abscess","volume":"91","author":"Ahmed","year":"2021","journal-title":"ANZ J Surg"},{"issue":"3","key":"10.1016\/j.eimce.2026.503052_bib0045","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1097\/01.sla.0000154265.14006.47","article-title":"An appraisal of surgical and percutaneous drainage for pyogenic liver abscesses larger than 5 cm","volume":"241","author":"Tan","year":"2005","journal-title":"Ann Surg"},{"issue":"5","key":"10.1016\/j.eimce.2026.503052_bib0050","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1007\/s15010-022-01793-z","article-title":"Large retrospective study analysing predictive factors of primary treatment failure, recurrence and death in pyogenic liver abscesses","volume":"50","author":"Rossi","year":"2022","journal-title":"Infection"},{"issue":"4","key":"10.1016\/j.eimce.2026.503052_bib0055","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.gastrohep.2012.01.001","article-title":"Pyogenic liver abscess: clinical presentation and predictors of unfavorable outcome","volume":"35","author":"L\u00f3pez-Cano G\u00f3mez","year":"2012","journal-title":"Gastroenterol Hepatol"},{"issue":"4","key":"10.1016\/j.eimce.2026.503052_bib0060","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1111\/liv.14760","article-title":"Clinical characteristics and management of 1572 patients with pyogenic liver abscess: a 12-year retrospective study","volume":"41","author":"Yin","year":"2021","journal-title":"Liver Int"},{"issue":"6","key":"10.1016\/j.eimce.2026.503052_bib0065","first-page":"483","article-title":"Pyogenic liver abscess: clinical profile, microbiological characteristics, and management in a Hong Kong hospital","volume":"41","author":"Lok","year":"2008","journal-title":"J Microbiol Immunol Infect"},{"issue":"3","key":"10.1016\/j.eimce.2026.503052_bib0070","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1136\/flgastro-2019-101240","article-title":"How to manage: liver abscess","volume":"12","author":"Trillos-Almanza","year":"2020","journal-title":"Frontline Gastroenterol"},{"key":"10.1016\/j.eimce.2026.503052_bib0075","doi-asserted-by":"crossref","DOI":"10.1038\/srep35890","article-title":"Clinical charateristics and outcome of pyogenic liver abscess with different size: 15-year experience from a single center","volume":"6","author":"Du","year":"2016","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.eimce.2026.503052_bib0080","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.1080\/07853890.2022.2110612","article-title":"Early percutaneous catheter drainage in protecting against prolonged fever among patients with pyogenic liver abscess: a retrospective cohort study","volume":"54","author":"Liu","year":"2022","journal-title":"Ann Med"},{"issue":"4","key":"10.1016\/j.eimce.2026.503052_bib0085","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0732-8893(03)00088-9","article-title":"Microbiology of liver abscesses and the predictive value of abscess gram stain and associated blood cultures","volume":"46","author":"Chemaly","year":"2003","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"1","key":"10.1016\/j.eimce.2026.503052_bib0090","doi-asserted-by":"crossref","first-page":"49","DOI":"10.4067\/S0716-10182009000100007","article-title":"Hepatic abscess: series of 107 cases and literature review","volume":"26","author":"Fantuzzi","year":"2009","journal-title":"Rev Chil Infectol"},{"issue":"9","key":"10.1016\/j.eimce.2026.503052_bib0095","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.amjmed.2023.05.003","article-title":"Bloodstream infection and colorectal cancer risk in Queensland Australia, 2000-2019","volume":"136","author":"Laupland","year":"2023","journal-title":"Am J Med"},{"issue":"5","key":"10.1016\/j.eimce.2026.503052_bib0100","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0011-3840(81)80018-4","article-title":"Management of hepatic abscess","volume":"18","author":"Balasegaram","year":"1981","journal-title":"Curr Probl Surg"},{"issue":"6","key":"10.1016\/j.eimce.2026.503052_bib0105","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1159\/000050194","article-title":"Pyogenic liver abscess: an audit of 10 years\u2019 experience and analysis of risk factors","volume":"18","author":"Lee","year":"2001","journal-title":"Dig Surg"},{"issue":"11","key":"10.1016\/j.eimce.2026.503052_bib0110","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1086\/425616","article-title":"Pyogenic liver abscess: recent trends in etiology and mortality","volume":"39","author":"Rahimian","year":"2004","journal-title":"Clin Infect Dis"},{"issue":"2","key":"10.1016\/j.eimce.2026.503052_bib0115","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0002-9610(00)00564-X","article-title":"Clinical course, treatment, and multivariate analysis of risk factors for pyogenic liver abscess","volume":"181","author":"Alvarez P\u00e9rez","year":"2001","journal-title":"Am J Surg"},{"issue":"9","key":"10.1016\/j.eimce.2026.503052_bib0120","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1046\/j.1440-1746.2002.02787.x","article-title":"Pyogenic liver abscess: retrospective analysis of 80 cases over a 10-year period","volume":"17","author":"Wong","year":"2002","journal-title":"J Gastroenterol Hepatol"},{"issue":"2","key":"10.1016\/j.eimce.2026.503052_bib0125","first-page":"80","article-title":"Presentation, diagnosis and treatment of pyogenic liver abscess: analysis of a series of 63 cases","volume":"13","author":"Corbella","year":"1995","journal-title":"Enferm Infecc Microbiol Clin"},{"issue":"1","key":"10.1016\/j.eimce.2026.503052_bib0130","first-page":"45","article-title":"Pyogenic liver abscesses: treatment results and analysis of the risk factors","volume":"67","author":"\u00c1lvarez P\u00e9rez","year":"1999","journal-title":"Cir Esp"},{"issue":"6","key":"10.1016\/j.eimce.2026.503052_bib0135","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1111\/apt.14512","article-title":"Treatment with proton pump inhibitors is associated with increased mortality in patients with pyogenic liver abscess","volume":"47","author":"Bettinger","year":"2018","journal-title":"Aliment Pharmacol Ther"},{"issue":"1","key":"10.1016\/j.eimce.2026.503052_bib0140","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-63819-w","article-title":"Clinical management, pathogen spectrum and outcomes in patients with pyogenic liver abscess in a German tertiary-care hospital","volume":"14","author":"Wendt","year":"2024","journal-title":"Sci Rep"},{"key":"10.1016\/j.eimce.2026.503052_bib0145","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1186\/s12876-024-03391-9","article-title":"Prognostic risk factors for pyogenic liver abscess caused by klebsiella pneumoniae","volume":"24","author":"Lyu","year":"2024","journal-title":"BMC Gastroenterol"},{"issue":"1","key":"10.1016\/j.eimce.2026.503052_bib0150","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12879-021-05873-7","article-title":"Maximal diameter of liver abscess independently predicts prolonged hospitalization and poor prognosis in patients with pyogenic liver abscess","volume":"21","author":"Lee","year":"2021","journal-title":"BMC Infect Dis"}],"container-title":["Enfermedades infecciosas y microbiologia clinica (English ed.)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2529993X26000298?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2529993X26000298?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T16:25:06Z","timestamp":1772900706000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2529993X26000298"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["S2529993X26000298"],"URL":"https:\/\/doi.org\/10.1016\/j.eimce.2026.503052","relation":{},"ISSN":["2529-993X"],"issn-type":[{"value":"2529-993X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Liver abscesses: Clinical-epidemiological, microbiological characteristics and mortality predictors","name":"articletitle","label":"Article Title"},{"value":"Enfermedades infecciosas y microbiologia clinica (English ed.)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eimce.2026.503052","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.eimc.2025.503052","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Sociedad Espa\u00f1ola de Enfermedades Infecciosas y Microbiolog\u00eda Cl\u00ednica. Published by Elsevier Espa\u00f1a, S.L.U. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"503052"}}