{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T08:53:19Z","timestamp":1772959999886,"version":"3.50.1"},"reference-count":33,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Enfermedades infecciosas y microbiologia clinica (English ed.)"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.eimce.2026.503106","type":"journal-article","created":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T16:24:39Z","timestamp":1772900679000},"page":"503106","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Gonococcal orbital cellulitis in an adolescent: A diagnostic challenge in determining the transmission pathway"],"prefix":"10.1016","volume":"44","author":[{"given":"Samantha","family":"P\u00e9rez-Cavazos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adri\u00e1n","family":"Camacho-Ortiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"P\u00e9rez-Alba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samanta Denis","family":"Ibarra-Trevi\u00f1o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.eimce.2026.503106_bib0170","series-title":"STI Statistics. Sexually Transmitted Infections Surveillance, 2023","author":"CDC","year":"2024"},{"key":"10.1016\/j.eimce.2026.503106_bib0175","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/s41572-019-0128-6","article-title":"Gonorrhoea","volume":"5","author":"Unemo","year":"2019","journal-title":"Nat Rev Dis Primer"},{"key":"10.1016\/j.eimce.2026.503106_bib0180","first-page":"967471","article-title":"Pharyngeal gonorrhoea in women: an important reservoir for increasing Neisseria gonorrhoeae prevalence in urban Australian heterosexuals?","volume":"2013","author":"Lusk","year":"2013","journal-title":"J Sex Transm Dis"},{"key":"10.1016\/j.eimce.2026.503106_bib0185","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1186\/s12879-021-06381-4","article-title":"Gonorrhoea: a systematic review of prevalence reporting globally","volume":"21","author":"Whelan","year":"2021","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.eimce.2026.503106_bib0190","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3390\/microorganisms12010015","article-title":"Intersociety position statement on the prevention of ophthalmia neonatorum in Italy","volume":"12","author":"Tzialla","year":"2023","journal-title":"Microorganisms"},{"key":"10.1016\/j.eimce.2026.503106_bib0195","first-page":"1442","article-title":"Five-year review of ocular Neisseria gonorrhoeae infections presenting to ophthalmology departments in Greater Glasgow & Clyde, Scotland","volume":"36","author":"Butler","year":"2022","journal-title":"Eye Lond Engl"},{"key":"10.1016\/j.eimce.2026.503106_bib0200","doi-asserted-by":"crossref","first-page":"2687","DOI":"10.4103\/IJO.IJO_3283_22","article-title":"Bacterial orbital cellulitis \u2013 a review","volume":"71","author":"Yadalla","year":"2023","journal-title":"Indian J Ophthalmol"},{"key":"10.1016\/j.eimce.2026.503106_bib0205","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.rr7004a1","article-title":"Sexually transmitted infections treatment guidelines, 2021","volume":"70","author":"Workowski","year":"2021","journal-title":"MMWR Recomm Rep"},{"key":"10.1016\/j.eimce.2026.503106_bib0210","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1001\/archopht.1979.01020020561013","article-title":"Orbital cellulitis due to Neisseria gonorrhoeae in an enucleated socket","volume":"97","author":"Frazier","year":"1960","journal-title":"Arch Ophthalmol Chic Ill"},{"key":"10.1016\/j.eimce.2026.503106_bib0215","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2018-227787","article-title":"Gonococcal orbital cellulitis","volume":"12","author":"Oliveira","year":"2019","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.eimce.2026.503106_bib0220","article-title":"Conjuntivitis en el world pride","author":"Barrios","year":"2019","journal-title":"Rev Esp Casos Cl\u00ednicos En Med Interna"},{"key":"10.1016\/j.eimce.2026.503106_bib0225","doi-asserted-by":"crossref","first-page":"e196","DOI":"10.1017\/S095026882300170X","article-title":"Prevalence of Neisseria gonorrhoeae and Chlamydia trachomatis infections among adolescent men who have sex with men and transgender women in Salvador, Northeast Brazil","volume":"151","author":"Oliveira","year":"2023","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.eimce.2026.503106_bib0230","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1186\/s12889-023-15946-8","article-title":"Comparison of the burden of self-reported bacterial sexually transmitted infections among men having sex with men across 68 countries on four continents","volume":"23","author":"Marcus","year":"2023","journal-title":"BMC Public Health"},{"key":"10.1016\/j.eimce.2026.503106_bib0235","doi-asserted-by":"crossref","DOI":"10.1177\/0956462420949126","article-title":"2020 European guideline for the diagnosis and treatment of gonorrhoea in adults","author":"Unemo","year":"2020","journal-title":"Int J STD AIDS"},{"key":"10.1016\/j.eimce.2026.503106_bib0240","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.jflm.2007.04.001","article-title":"What is the evidence for non-sexual transmission of gonorrhoea in children after the neonatal period? A systematic review","volume":"14","author":"Goodyear-Smith","year":"2007","journal-title":"J Forensic Leg Med"},{"key":"10.1016\/j.eimce.2026.503106_bib0245","first-page":"e243","article-title":"Neisseria gonorrhoeae: un agente causal infrecuente de celulitis periorbitaria en un ni\u00f1o","volume":"115","author":"Pereira-Ospina","year":"2017","journal-title":"Arch Argent Pediatr\u00eda"},{"key":"10.1016\/j.eimce.2026.503106_bib0250","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1542\/hpeds.2023-007144","article-title":"Improving sexual history documentation in teenagers","volume":"14","author":"Kaufman","year":"2024","journal-title":"Hosp Pediatr"},{"key":"10.1016\/j.eimce.2026.503106_bib0255","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1093\/pch\/pxac117","article-title":"Considerations for privacy and confidentiality in adolescent health care service delivery","volume":"28","author":"Agostino","year":"2023","journal-title":"Paediatr Child Health"},{"key":"10.1016\/j.eimce.2026.503106_bib0260","series-title":"For Providers: Teens Visiting a Health Clinic","author":"CDC. Reproductive Health","year":"2025"},{"key":"10.1016\/j.eimce.2026.503106_bib0265","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1089\/mdr.2023.0259","article-title":"Antimicrobial resistance in gonorrhea","volume":"30","author":"Vitiello","year":"2024","journal-title":"Microb Drug Resist Larchmt N"},{"key":"10.1016\/j.eimce.2026.503106_bib0270","series-title":"2019 Antibiotic Resistance Threats Report","article-title":"CDC. Antimicrobial Resistance","year":"2024"},{"issue":"Pt 6","key":"10.1016\/j.eimce.2026.503106_bib0275","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1099\/jmm.0.46031-0","article-title":"Bilateral orbital cellulitis due to Neisseria gonorrhoeae and Staphylococcus aureus: a previously unreported case","volume":"54","author":"Raja","year":"2005","journal-title":"J Med Microbiol"},{"key":"10.1016\/j.eimce.2026.503106_bib0280","doi-asserted-by":"crossref","DOI":"10.18203\/2349-3291.ijcp20211433","article-title":"A cross preseptal and postseptal gonococcal orbital cellulitis in a 3-year-old male","volume":"8","author":"Simon","year":"2021","journal-title":"Int J Contemp Pediatr"},{"key":"10.1016\/j.eimce.2026.503106_bib0285","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1136\/sextrans-2020-054850","article-title":"Pain in the eye: a case of gonococcal orbital cellulitis","volume":"97","author":"Miller","year":"2021","journal-title":"Sex Transm Infect"},{"key":"10.1016\/j.eimce.2026.503106_bib0290","doi-asserted-by":"crossref","first-page":"198","DOI":"10.4103\/ojo.ojo_331_20","article-title":"Ocular Neisseria gonorrhea in a patient on immune checkpoint inhibitors","volume":"14","author":"Sopeyin","year":"2021","journal-title":"Oman J Ophthalmol"},{"key":"10.1016\/j.eimce.2026.503106_bib0295","doi-asserted-by":"crossref","first-page":"e46","DOI":"10.1056\/NEJMicm2117893","article-title":"Ocular gonorrhea","volume":"386","author":"Suyama","year":"2022","journal-title":"N Engl J Med"},{"issue":"Pt 1","key":"10.1016\/j.eimce.2026.503106_bib0300","first-page":"130","article-title":"Neisseria gonorrhoeae: a previously unreported cause of pre-septal cellulitis","volume":"11","author":"Henderson","year":"1997","journal-title":"Eye Lond Engl"},{"key":"10.1016\/j.eimce.2026.503106_bib0305","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1258\/095646206775455748","article-title":"Neisseria gonorrhoeae: a rare cause of preseptal cellulitis?","volume":"17","author":"Green","year":"2006","journal-title":"Int J STD AIDS"},{"key":"10.1016\/j.eimce.2026.503106_bib0310","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1258\/ijsa.2008.007306","article-title":"Outpatient management of severe gonococcal ophthalmia without genital infection","volume":"19","author":"Annan","year":"2008","journal-title":"Int J STD AIDS"},{"key":"10.1016\/j.eimce.2026.503106_bib0315","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.jmii.2015.05.024","article-title":"Preseptal cellulitis caused by Neisseria gonorrhoeae: a rare disease need to be vigilant","volume":"50","author":"Yao","year":"2017","journal-title":"J Microbiol Immunol Infect Wei Mian Yu Gan Ran Za Zhi"},{"key":"10.1016\/j.eimce.2026.503106_bib0320","doi-asserted-by":"crossref","first-page":"269","DOI":"10.5694\/mja17.00223","article-title":"Invasive Neisseria gonorrhoeae producing pre-septal cellulitis and keratoconjunctivitis: diagnosis and management","volume":"207","author":"Varma","year":"2017","journal-title":"Med J Aust"},{"key":"10.1016\/j.eimce.2026.503106_bib0325","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1097\/OLQ.0000000000001055","article-title":"Neisseria gonorrhoeae as a rare cause of preseptal cellulitis","volume":"46","author":"Adamson","year":"2019","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.eimce.2026.503106_bib0330","unstructured":"Fish D. More Than Meets The Eye: Gonococcal Conjunctivitis in Children. J Hosp Med [Internet]. Available from: https:\/\/shmabstracts.org\/abstract\/more-than-meets-the-eye-gonococcal-conjunctivitis-in-children\/ Cited 11.6.25."}],"container-title":["Enfermedades infecciosas y microbiologia clinica (English ed.)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2529993X26000389?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2529993X26000389?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T01:34:57Z","timestamp":1772933697000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2529993X26000389"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["S2529993X26000389"],"URL":"https:\/\/doi.org\/10.1016\/j.eimce.2026.503106","relation":{},"ISSN":["2529-993X"],"issn-type":[{"value":"2529-993X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gonococcal orbital cellulitis in an adolescent: A diagnostic challenge in determining the transmission pathway","name":"articletitle","label":"Article Title"},{"value":"Enfermedades infecciosas y microbiologia clinica (English ed.)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eimce.2026.503106","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Sociedad Espa\u00f1ola de Enfermedades Infecciosas y Microbiolog\u00eda Cl\u00ednica. Published by Elsevier Espa\u00f1a, S.L.U. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"503106"}}