{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T05:13:43Z","timestamp":1768454023318,"version":"3.49.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Cancer"],"published-print":{"date-parts":[[2005,3]]},"DOI":"10.1016\/j.ejca.2004.10.029","type":"journal-article","created":{"date-parts":[[2005,1,13]],"date-time":"2005-01-13T08:56:44Z","timestamp":1105606604000},"page":"549-554","source":"Crossref","is-referenced-by-count":60,"title":["Early detection of breast and ovarian cancer in families with BRCA mutations"],"prefix":"10.1016","volume":"41","author":[{"given":"H.F.A.","family":"Vasen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Tesfay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Boonstra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.J.E.","family":"Mourits","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Rutgers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Verheyen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Oosterwijk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Beex","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejca.2004.10.029_bib1","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1086\/375033","article-title":"Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in cases unselected for family history: a combined analysis of 22 studies","volume":"72","author":"Antoniou","year":"2003","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.ejca.2004.10.029_bib2","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.1016\/S0959-8049(98)00288-3","article-title":"Current policies for surveillance and management in women at risk of breast and ovarian cancer: a survey among 16 European family cancer clinics. European Familial Breast Cancer Collaborative Group","volume":"34","author":"Vasen","year":"1998","journal-title":"Eur J Cancer"},{"issue":"Suppl. 8","key":"10.1016\/j.ejca.2004.10.029_bib3","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3109\/02841869609098515","article-title":"Inherited breast carcinoma-prospective findings in 1194 women at risk","volume":"35","author":"Moller","year":"1996","journal-title":"Acta Oncol"},{"key":"10.1016\/j.ejca.2004.10.029_bib4","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S0959-8049(98)00005-7","article-title":"Screening by mammography, women with a family history of breast cancer","volume":"34","author":"Lalloo","year":"1998","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ejca.2004.10.029_bib5","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/S0959-8049(97)00365-1","article-title":"Screening women aged less than 50 years with a family history of breast cancer","volume":"34","author":"Kollias","year":"1998","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ejca.2004.10.029_bib6","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1200\/JCO.2001.19.4.924","article-title":"Effectiveness of breast cancer surveillance in BRCA1\/2 gene mutation carriers and women with high familial risk","volume":"19","author":"Brekelmans","year":"2001","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2004.10.029_bib7","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1200\/JCO.20.5.1260","article-title":"Outcome of preventive surgery and screening for breast and ovarian cancer in BRCA mutation carriers","volume":"20","author":"Scheuer","year":"2002","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2004.10.029_bib8","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1056\/NEJMoa031759","article-title":"Efficacy of MRI and mammography for breast-cancer screening in women with a familial or genetic predisposition","volume":"351","author":"Kriege","year":"2004","journal-title":"NEJM"},{"key":"10.1016\/j.ejca.2004.10.029_bib9","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1002\/uog.65","article-title":"Results from an ultrasound-based familial ovarian cancer screening clinic: a 10-year observational study","volume":"21","author":"Taylor","year":"2003","journal-title":"Ultrasound Obst Gyn"},{"key":"10.1016\/j.ejca.2004.10.029_bib10","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1080\/j.1600-0412.1999.781013.x","article-title":"Prospectively detected cancer in familial breast\/ovarian cancer screening","volume":"78","author":"Dorum","year":"1997","journal-title":"Acta Obstet Gyn Scan"},{"key":"10.1016\/j.ejca.2004.10.029_bib11","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/S0959-8049(05)80298-9","article-title":"Clinical heterogeneity of hereditary breast cancer and its impact on screening protocols: the Dutch experience on 24 families under surveillance","volume":"29A","author":"Vasen","year":"1993","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ejca.2004.10.029_bib12","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1056\/NEJM199705153362022","article-title":"Decision analysis-effects of prophylactic mastectomy and oophorectomy on life expectancy among women with BRCA1 or BRCA2 mutations","volume":"336","author":"Schrag","year":"1997","journal-title":"New Engl J Med"},{"key":"10.1016\/j.ejca.2004.10.029_bib13","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1056\/NEJM199901143400201","article-title":"Efficacy of bilateral prophylactic mastectomy in women with a family history of breast cancer","volume":"340","author":"Hartmann","year":"1999","journal-title":"New Engl J Med"},{"key":"10.1016\/j.ejca.2004.10.029_bib14","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1056\/NEJM200107193450301","article-title":"Breast cancer after prophylactic bilateral mastectomy in women with a BRCA1 or BRCA2 mutation","volume":"345","author":"Meijers-Heijboer","year":"2001","journal-title":"New Engl J Med"},{"key":"10.1016\/j.ejca.2004.10.029_bib15","first-page":"131","article-title":"Long-term psychosocial impact of prophylactic mastectomy and immediate breast reconstruction. Abstracts XVIth symposium of The Netherlands Foundation for the Detection of Hereditary Tumors","volume":"2","author":"Bresser","year":"2003","journal-title":"Familial Cancer"},{"key":"10.1016\/j.ejca.2004.10.029_bib16","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1056\/NEJMoa012158","article-title":"Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations","volume":"346","author":"Rebbeck","year":"2002","journal-title":"New Engl J Med"},{"key":"10.1016\/j.ejca.2004.10.029_bib17","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1016\/S0140-6736(00)03258-X","article-title":"Tamoxifen and risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers: a case-control study. Hereditary Breast Cancer Clinical Study Group","volume":"356","author":"Narod","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.ejca.2004.10.029_bib18","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1148\/radiology.215.1.r00ap01267","article-title":"Breast MR imaging screening in 192 women proved or suspected to be carriers of a breast cancer susceptibility gene: preliminary results","volume":"215","author":"Kuhl","year":"2000","journal-title":"Radiology"},{"key":"10.1016\/j.ejca.2004.10.029_bib19","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1093\/jnci\/93.14.1095","article-title":"Magnetic resonance imaging and mammography in women with a hereditary risk of breast cancer","volume":"93","author":"Stoutjesdijk","year":"2001","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.ejca.2004.10.029_bib20","doi-asserted-by":"crossref","first-page":"3524","DOI":"10.1200\/JCO.2001.19.15.3524","article-title":"Comparison of breast magnetic resonance imaging, mammography, and ultrasound for surveillance of women at high risk for hereditary breast cancer","volume":"19","author":"Warner","year":"2001","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2004.10.029_bib21","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1002\/path.1000","article-title":"Dysplastic changes in prophylactically removed Fallopian tubes of women predisposed to developing ovarian cancer","volume":"195","author":"Piek","year":"2001","journal-title":"J Pathol"}],"container-title":["European Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804904009876?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804904009876?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,30]],"date-time":"2019-01-30T03:50:23Z","timestamp":1548820223000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959804904009876"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,3]]}},"alternative-id":["S0959804904009876"],"URL":"https:\/\/doi.org\/10.1016\/j.ejca.2004.10.029","relation":{},"ISSN":["0959-8049"],"issn-type":[{"value":"0959-8049","type":"print"}],"subject":[],"published":{"date-parts":[[2005,3]]}}}