{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T05:16:34Z","timestamp":1789017394723,"version":"build-2803163510"},"reference-count":77,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Cancer"],"published-print":{"date-parts":[[2007,3]]},"DOI":"10.1016\/j.ejca.2006.11.002","type":"journal-article","created":{"date-parts":[[2006,12,14]],"date-time":"2006-12-14T12:10:57Z","timestamp":1166098257000},"page":"683-689","source":"Crossref","is-referenced-by-count":66,"title":["Osteonecrosis in children and adolescents with cancer \u2013 An adverse effect of systemic therapy"],"prefix":"10.1016","volume":"43","author":[{"given":"Alessandra","family":"Sala","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Leonard A.","family":"Mattano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald D.","family":"Barr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejca.2006.11.002_bib1","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.2106\/00004623-197355070-00002","article-title":"The silent hip in idiopathic aseptic necrosis","volume":"55","author":"Marcus","year":"1973","journal-title":"J Bone Joint Surg A"},{"key":"10.1016\/j.ejca.2006.11.002_bib2","doi-asserted-by":"crossref","first-page":"47","DOI":"10.2106\/00004623-198264010-00008","article-title":"The treatment of spontaneous osteonecrosis of the knee by high tibial osteotomy with and without bone grafting or drilling of the lesion","volume":"64","author":"Koshino","year":"1982","journal-title":"J Bone Joint Surg A"},{"key":"10.1016\/j.ejca.2006.11.002_bib3","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1302\/0301-620X.67B1.3155745","article-title":"Idiopathic bone necrosis of the femoral head","volume":"67B","author":"Ficat","year":"1985","journal-title":"J Bone Joint Surg"},{"key":"10.1016\/j.ejca.2006.11.002_bib4","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1302\/0301-620X.73B1.1991778","article-title":"Natural history of non-traumatic avascular necrosis of the femoral head","volume":"73B","author":"Ohzono","year":"1991","journal-title":"J Bone Joint Surg"},{"key":"10.1016\/j.ejca.2006.11.002_bib5","unstructured":"ARCO Committee on Terminology and Staging. ARCO Newslett 1992; 4: 41\u201346."},{"key":"10.1016\/j.ejca.2006.11.002_bib6","doi-asserted-by":"crossref","first-page":"215","DOI":"10.2106\/00004623-199402000-00007","article-title":"Prediction of relapse with magnetic resonance imaging of avascular necrosis of the femoral head","volume":"76A","author":"Shimizu","year":"1994","journal-title":"J Bone Joint Surg"},{"key":"10.1016\/j.ejca.2006.11.002_bib7","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1302\/0301-620X.77B1.7822393","article-title":"A quantitative system for staging avascular necrosis","volume":"77B","author":"Steinberg","year":"1995","journal-title":"J Bone Joint Surg"},{"key":"10.1016\/j.ejca.2006.11.002_bib8","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/j.crad.2004.04.014","article-title":"MRI of osteonecrosis","volume":"59","author":"Saini","year":"2004","journal-title":"Clin Radiol"},{"key":"10.1016\/j.ejca.2006.11.002_bib9","first-page":"470","article-title":"MRI of knee osteonecrosis in children with leukemia and lymphoma: Part 1, observer agreement","volume":"186","author":"Karimova","year":"2006","journal-title":"Am J Radiol"},{"key":"10.1016\/j.ejca.2006.11.002_bib10","first-page":"477","article-title":"MRI of knee osteonecrosis in children with leukemia and lymphoma: Part 2, clinical and imaging patterns","volume":"186","author":"Karimova","year":"2006","journal-title":"Am J Radiol"},{"key":"10.1016\/j.ejca.2006.11.002_bib11","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1177\/014107688307600810","article-title":"Avascular necrosis of bone: a review","volume":"76","author":"Nixon","year":"1983","journal-title":"J Roy Soc Med"},{"key":"10.1016\/j.ejca.2006.11.002_bib12","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1056\/NEJM199205283262206","article-title":"Non-traumatic necrosis of bone (osteonecrosis)","volume":"326","author":"Mankin","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejca.2006.11.002_bib13","first-page":"81","article-title":"Pseudo Perthes\u2019 disease caused by acute lymphatic leukemia","volume":"18","author":"Zaunschirm","year":"1983","journal-title":"Padiatr Padol"},{"key":"10.1016\/j.ejca.2006.11.002_bib14","first-page":"37","article-title":"Necrosis of the caput femoris in complete remission of lymphoblastic leukemia","volume":"189","author":"Kaufmann","year":"1977","journal-title":"Klin Padiatr"},{"key":"10.1016\/j.ejca.2006.11.002_bib15","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1038\/sj.leu.2402139","article-title":"Magnetic resonance imaging detection of avascular necrosis of bone in children receiving intensive prednisone therapy for acute lymphoblastic leukemia or non-Hodgkin lymphoma","volume":"15","author":"Ribeiro","year":"2001","journal-title":"Leukemia"},{"key":"10.1016\/j.ejca.2006.11.002_bib16","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1007\/BF01958270","article-title":"Osteonecrosis of vertebrae in a child with acute lymphocytic leukemia during L-asparaginase therapy","volume":"149","author":"Hanada","year":"1989","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.ejca.2006.11.002_bib17","first-page":"286","article-title":"Avascular necrosis of bone in children with acute lymphoblastic leukemia","volume":"25","author":"Kardos","year":"1995","journal-title":"Med Pediatr Oncol"},{"key":"10.1016\/j.ejca.2006.11.002_bib18","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1007\/BF00445806","article-title":"Avascular necrosis of bone in neuroblastoma treated with combination chemotherapy","volume":"143","author":"Ishii","year":"1984","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.ejca.2006.11.002_bib19","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1097\/00003086-200001000-00030","article-title":"The Nicolas Andry Award. The pathogenesis and prevention of steroid-induced osteonecrosis","volume":"370","author":"Wang","year":"2000","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib20","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1038\/sj.bmt.1704360","article-title":"Bone mineral density and osteonecrosis in survivors of childhood allogeneic bone marrow transplantation","volume":"33","author":"Kaste","year":"2004","journal-title":"Bone Marrow Transpl"},{"key":"10.1016\/j.ejca.2006.11.002_bib21","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1097\/00003086-198607000-00007","article-title":"Osteonecrosis of bone. Current concepts as to etiology and pathogenesis","volume":"208","author":"Cruess","year":"1986","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib22","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1053\/sarh.2002.33724b","article-title":"Pathogenesis and natural history of osteonecrosis","volume":"32","author":"Assouline-Dayan","year":"2002","journal-title":"Sem Arthritis Rheum"},{"key":"10.1016\/j.ejca.2006.11.002_bib23","first-page":"242","article-title":"Ischemic necrosis of the femoral head. Part 1. Accumulative cell stress: a hypothesis for the etiology of idiopathic osteonecrosis","volume":"32","author":"Kenzora","year":"1983","journal-title":"Instr Course Lect"},{"key":"10.1016\/j.ejca.2006.11.002_bib24","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/j.prp.2004.10.003","article-title":"Bone marrow fat-cell enlargement in early steroid-induced osteonecrosis: a histomorphometic study of autopsy cases","volume":"200","author":"Motomura","year":"2005","journal-title":"Pathol Res Pract"},{"key":"10.1016\/j.ejca.2006.11.002_bib25","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1097\/00029330-200604010-00012","article-title":"Dexamethasone-induced adipogenesis in primary marrow stromal cell cultures: mechanism of steroid-induced osteonecrosis","volume":"119","author":"Yin","year":"2006","journal-title":"Chin Med J"},{"key":"10.1016\/j.ejca.2006.11.002_bib26","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1002\/jor.20078","article-title":"Alterations in the differentiation ability of mesenchymal stem cells in patients with non-traumatic osteonecrosis of the femoral head: Comparative analysis according to the risk factors","volume":"24","author":"Lee","year":"2006","journal-title":"J Orthop Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib27","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1002\/(SICI)1096-911X(199906)32:6<474::AID-MPO23>3.0.CO;2-S","article-title":"Osteonecrosis in children treated for acute leukemia","volume":"32","year":"1999","journal-title":"Med Pediatr Oncol"},{"key":"10.1016\/j.ejca.2006.11.002_bib28","doi-asserted-by":"crossref","first-page":"3262","DOI":"10.1200\/JCO.2000.18.18.3262","article-title":"Osteonecrosis as a complication of treating acute lymphoblastic leukemia in children: A report from the Children\u2019s Cancer Group","volume":"18","author":"Mattano","year":"2000","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2006.11.002_bib29","doi-asserted-by":"crossref","first-page":"3066","DOI":"10.1200\/JCO.2001.19.12.3066","article-title":"Bony morbidity in children treated for acute lymphoblastic leukemia","volume":"19","author":"Strauss","year":"2001","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2006.11.002_bib30","first-page":"747","article-title":"Osteonecrosis: an emerging complication of intensive chemotherapy for childhood acute lymphoblastic leukemia","volume":"88","author":"Arico","year":"2003","journal-title":"Haematologica"},{"key":"10.1016\/j.ejca.2006.11.002_bib31","doi-asserted-by":"crossref","unstructured":"Hogler W, Wehl G, van Staa T, Meister B, Klein-Franke A, Kropshofer G. Incidence of skeletal complications during treatment of childhood acute lymphoblastic leukemia: Comparison of fracture risk with the general practice research database. Pediatr Blood Cancer 2005 (e-publication ahead of print).","DOI":"10.1002\/pbc.20701"},{"key":"10.1016\/j.ejca.2006.11.002_bib32","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1002\/pbc.20244","article-title":"Osteonecrosis: A treatment-related toxicity in childhood acute lymphoblastic leukemia (ALL) \u2013 experiences from trial ALL-BFM 95","volume":"44","author":"Burger","year":"2005","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.ejca.2006.11.002_bib33","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1097\/01.mph.0000163215.37147.13","article-title":"Aseptic osteonecrosis in children and adolescents treated for hemato-oncologic diseases: a 13 year longitudinal observational study","volume":"27","author":"Lackner","year":"2005","journal-title":"J Pediatr Hematol Oncol"},{"key":"10.1016\/j.ejca.2006.11.002_bib34","first-page":"3920","article-title":"Pharmacogenetic risk factors for osteonecrosis of the hip among children with leukemia","volume":"19","author":"Relling","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2006.11.002_bib35","doi-asserted-by":"crossref","first-page":"2294","DOI":"10.1056\/NEJMoa042480","article-title":"Type II collagen gene variants and inherited osteonecrosis of the femoral head","volume":"352","author":"Liu","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejca.2006.11.002_bib36","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s00402-004-0760-8","article-title":"Factor V Leiden and the prothrombin 20210 A gene mutation and osteonecrosis of the knee","volume":"125","author":"Bjorkman","year":"2005","journal-title":"Arch Orthop Trauma Surg"},{"key":"10.1016\/j.ejca.2006.11.002_bib37","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.transproceed.2005.12.062","article-title":"Association of corticosteroids and factor V, prothrombin and MTHFR gene mutations with avascular osteonecrosis in renal allograft recipients","volume":"38","author":"Celik","year":"2006","journal-title":"Transpl Proc"},{"key":"10.1016\/j.ejca.2006.11.002_bib38","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1097\/00003086-199909000-00017","article-title":"The plasminogen activator inhibitor-1 gene, hypofibrinolysis and osteonecrosis","volume":"366","author":"Glueck","year":"1999","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib39","first-page":"111","article-title":"The 677C\u2192T mutation of the methylene-tetrahydrofolate reductase gene in the pathogenesis of osteonecrosis of the femoral head","volume":"87","author":"Zalavras","year":"2002","journal-title":"Haematologica"},{"key":"10.1016\/j.ejca.2006.11.002_bib40","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1055\/s-2003-45496","article-title":"Methylenetetrahydrofolate reductase gene polymorphism and glucocorticoid intake in children with ALL and aseptic osteonecrosis","volume":"215","author":"Bernbeck","year":"2003","journal-title":"Klin Padiatr"},{"key":"10.1016\/j.ejca.2006.11.002_bib41","doi-asserted-by":"crossref","first-page":"2594","DOI":"10.2106\/00004623-200412000-00002","article-title":"Spontaneous resolution of osteonecrosis of the femoral head","volume":"86A","author":"Cheng","year":"2004","journal-title":"J Bone Joint Surg"},{"key":"10.1016\/j.ejca.2006.11.002_bib42","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1097\/00003086-199912000-00033","article-title":"Symptomatic multifocal osteonecrosis. A multi center study","volume":"369","year":"1999","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib43","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1097\/01.blo.0000137548.22577.96","article-title":"Childhood cancer survivors: an at-risk cohort for ankle osteonecrosis","volume":"430","author":"Chollet","year":"2005","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib44","doi-asserted-by":"crossref","first-page":"737","DOI":"10.2106\/00004623-196951040-00012","article-title":"Traumatic arthritis of the hip after dislocation and acetabular fractures: Treatment by mold arthroplasty. An end result study using a new method of result evaluation","volume":"51","author":"Harris","year":"1969","journal-title":"J Bone Joint Surg A"},{"key":"10.1016\/j.ejca.2006.11.002_bib45","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1002\/(SICI)1096-911X(199710)29:4<260::AID-MPO5>3.0.CO;2-K","article-title":"Osteonecrosis in children treated for acute lymphoblastic leukemia: A magnetic resonance imaging study after treatment","volume":"29","author":"Ojala","year":"1997","journal-title":"Med Pediatr Oncol"},{"key":"10.1016\/j.ejca.2006.11.002_bib46","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/(SICI)1096-911X(199901)32:1<11::AID-MPO4>3.0.CO;2-F","article-title":"Osteonecrosis during the treatment of childhood acute lymphoblastic leukemia: a prospective MRI study","volume":"32","author":"Ojala","year":"1999","journal-title":"Med Pediatr Oncol"},{"key":"10.1016\/j.ejca.2006.11.002_bib47","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1097\/01.blo.0000150275.98701.4e","article-title":"Asymptomatic osteonecrosis: should it be treated?","volume":"429","author":"Hungerford","year":"2004","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib48","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1097\/01.blo.0000192365.58958.84","article-title":"Bilateral core decompression for osteonecrosis of the femoral head","volume":"441","author":"Israelite","year":"2005","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib49","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1097\/00003086-200103000-00025","article-title":"Intraosseous hypertension and venous congestion in osteonecrosis of the knee","volume":"384","author":"Uchio","year":"2001","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib50","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1097\/00004694-200005000-00012","article-title":"Avascular necrosis in children with acute lymphoblastic leukemia","volume":"20","author":"Wei","year":"2000","journal-title":"J Pediatr Orthop"},{"key":"10.1016\/j.ejca.2006.11.002_bib51","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1055\/s-2006-931902","article-title":"Osteonecrosis of the femoral head: comparison of clinical results for vascularised iliac and fibula bone grafting","volume":"22","author":"Yen","year":"2006","journal-title":"J Reconstr Microsurg"},{"key":"10.1016\/j.ejca.2006.11.002_bib52","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1097\/01.blo.0000150312.53937.6f","article-title":"Treatment of osteonecrosis of the femoral head with core decompression and human bone morphogenetic protein","volume":"429","author":"Lieberman","year":"2004","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib53","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1302\/0301-620X.81B2.8818","article-title":"Decrease in the mesenchymal stem cell pool in corticosteroid-induced osteonecrosis","volume":"81","author":"Hernigou","year":"1999","journal-title":"J Bone Joint Surg B"},{"key":"10.1016\/j.ejca.2006.11.002_bib54","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1517\/14712598.5.4.437","article-title":"Stem cell therapy for osteonecrosis of the femoral head","volume":"5","author":"Gangji","year":"2005","journal-title":"Expert Opin Biol Ther"},{"key":"10.1016\/j.ejca.2006.11.002_bib55","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1097\/00003086-200212000-00003","article-title":"Treatment of osteonecrosis with autologous bone marrow grafting","volume":"405","author":"Hernigou","year":"2002","journal-title":"Clin Ortho Relat Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib56","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.2106\/00004623-200406000-00006","article-title":"Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells","volume":"86","author":"Gangji","year":"2004","journal-title":"J Bone Joint Surg A"},{"key":"10.1016\/j.ejca.2006.11.002_bib57","first-page":"3","article-title":"Treatment of osteonecrosis of the femoral head by percutaneous decompression and autologous bone marrow mononuclear cell infusion","volume":"9","author":"Yan","year":"2006","journal-title":"Chin J Traumatol"},{"key":"10.1016\/j.ejca.2006.11.002_bib58","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1097\/00003086-199007000-00018","article-title":"The effect of electrical stimulation on osteonecrosis of the femoral head","volume":"256","author":"Trancik","year":"1990","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib59","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/00003086-199012000-00003","article-title":"Capacitance coupling as an adjunctive treatment for avascular necrosis","volume":"261","author":"Steinberg","year":"1990","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib60","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1055\/s-2004-832341","volume":"216","author":"Bernbeck","year":"2004","journal-title":"Klin Padiatr"},{"key":"10.1016\/j.ejca.2006.11.002_bib61","first-page":"669","article-title":"Nipedipine per os relieves the pain caused by osteonecrosis of the femur head","volume":"57","author":"Laroche","year":"1990","journal-title":"Rev Rhum Mal Osteoartic"},{"key":"10.1016\/j.ejca.2006.11.002_bib62","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1097\/01.blo.0000157539.67567.03","article-title":"Enoxaparin prevents progression of stages I and II osteonecrosis of the hip","volume":"435","author":"Glueck","year":"2005","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib63","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1080\/17453670610045894","article-title":"Pharmacological treatment of osteonecrosis","volume":"77","author":"Aspenberg","year":"2006","journal-title":"Acta Orthop"},{"key":"10.1016\/j.ejca.2006.11.002_bib64","doi-asserted-by":"crossref","first-page":"753","DOI":"10.7326\/0003-4819-144-10-200605160-00009","article-title":"Systematic review: bisphosphonates and osteonecrosis of the jaws","volume":"144","author":"Woo","year":"2006","journal-title":"Ann Int Med"},{"key":"10.1016\/j.ejca.2006.11.002_bib65","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1093\/rheumatology\/keh481","article-title":"Efficacy of Alendronate, a bisphosphonate, in the treatment of avn of the hip. A prospective open-label study","volume":"44","author":"Agarwala","year":"2005","journal-title":"Rheumatology"},{"key":"10.1016\/j.ejca.2006.11.002_bib66","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1097\/01.blo.0000194078.32776.31","article-title":"Does alendronate prevent collapse in osteonecrosis of the femoral head?","volume":"443","author":"Nishii","year":"2006","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib67","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.2106\/JBJS.D.02959","article-title":"The use of alendronate to prevent early collapse of the femoral head in patients with non-traumatic osteonecrosis. A randomized clinical study","volume":"87A","author":"Lai","year":"2005","journal-title":"J Bone Joint Surg"},{"issue":"Suppl. 11","key":"10.1016\/j.ejca.2006.11.002_bib68","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1002\/(SICI)1097-0215(1998)78:11+<35::AID-IJC11>3.0.CO;2-I","article-title":"Mineral and bone abnormalities in childhood acute lymphoblastic leukemia: Influence of disease, drugs and nutrition","author":"Atkinson","year":"1998","journal-title":"Int J Cancer"},{"key":"10.1016\/j.ejca.2006.11.002_bib69","unstructured":"Sala A, Talsma D, Webber C, Posgate S, Atkinson S, Barr R. Bone mineral status after treatment of malignant lymphoma in childhood and adolescence. Eur J Cancer Care [in press]."},{"key":"10.1016\/j.ejca.2006.11.002_bib70","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1191\/1078155205jp145oa","article-title":"Alendronate for steroid-induced osteopenia in children with acute lymphoblastic leukemia or non-Hodgkin lymphoma","volume":"11","author":"Wiernikowski","year":"2005","journal-title":"J Oncol Pharmacy Pract"},{"key":"10.1016\/j.ejca.2006.11.002_bib71","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.orthres.2004.11.015","article-title":"Zoledronic acid improves femoral head sphericity in a rat model of Perthes disease","volume":"23","author":"Little","year":"2005","journal-title":"J Orthop Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib72","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1359\/jbmr.2003.18.11.2016","article-title":"Zoledronic acid treatment results in retention of femoral head structure after traumatic osteonecrosis in young Wister rats","volume":"18","author":"Little","year":"2003","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib73","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.orthres.2004.08.013","article-title":"Vascular endothelial growth factor (VEGF) gene transfer enhances surgical revascularisation of necrotic bone","volume":"23","author":"Katsube","year":"2005","journal-title":"J Orthop Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib74","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1002\/jor.20097","article-title":"Expression of the angiomatrix and angiogenic proteins CYR61, CTGF and VEGF in osteonecrosis of the femoral head","volume":"24","author":"Radke","year":"2006","journal-title":"J Orthop Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib75","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/00003086-200105000-00022","article-title":"Statin therapy decreases the risk of osteonecrosis in patients receiving steroids","volume":"386","author":"Pritchett","year":"2001","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.ejca.2006.11.002_bib76","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/S8756-3282(03)00239-4","article-title":"Lovostatin inhibits adipogenic and stimulates osteogenic differentiation by suppressing PPARgamma2 and increasing Cbfal\/Runx2 expression in bone marrow mesenchymal cell cultures","volume":"33","author":"Li","year":"2003","journal-title":"Bone"},{"key":"10.1016\/j.ejca.2006.11.002_bib77","first-page":"210","article-title":"Drug therapy increases bone density in osteonecrosis of the femoral head in canines","volume":"13","author":"Bowers","year":"2004","journal-title":"J Surg Orthop Adv"}],"container-title":["European Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804906009622?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804906009622?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T23:46:55Z","timestamp":1683676015000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959804906009622"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3]]},"references-count":77,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["S0959804906009622"],"URL":"https:\/\/doi.org\/10.1016\/j.ejca.2006.11.002","relation":{},"ISSN":["0959-8049"],"issn-type":[{"value":"0959-8049","type":"print"}],"subject":[],"published":{"date-parts":[[2007,3]]}}}