{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T10:46:09Z","timestamp":1790505969260,"version":"4.1.0"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","ejcancer.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Cancer"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1016\/j.ejca.2015.11.023","type":"journal-article","created":{"date-parts":[[2016,1,19]],"date-time":"2016-01-19T16:25:33Z","timestamp":1453220733000},"page":"21-30","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"special_numbering":"C","title":["Polychlorinated biphenyls and their association with survival following breast cancer"],"prefix":"10.1016","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6562-8577","authenticated-orcid":false,"suffix":"Jr.","given":"Humberto","family":"Parada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary S.","family":"Wolff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence S.","family":"Engel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sybil M.","family":"Eng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikhil K.","family":"Khankari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfred I.","family":"Neugut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan L.","family":"Teitelbaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilie D.","family":"Gammon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejca.2015.11.023_bib1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3322\/caac.21208","article-title":"Cancer statistics, 2014","author":"Siegel","year":"2014","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.ejca.2015.11.023_bib2","unstructured":"National Cancer Institute. SEER Stat Fact Sheets: Breast Cancer 2015. http:\/\/seer.cancer.gov\/statfacts\/html\/breast.html (accessed March 1, 2015)."},{"key":"10.1016\/j.ejca.2015.11.023_bib3","doi-asserted-by":"crossref","first-page":"595167","DOI":"10.1155\/2010\/595167","article-title":"Breast cancer in developing countries: opportunities for improved survival","volume":"2010","author":"Shulman","year":"2010","journal-title":"J Oncol"},{"key":"10.1016\/j.ejca.2015.11.023_bib4","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/s10549-007-9556-1","article-title":"An overview of prognostic factors for long-term survivors of breast cancer","volume":"107","author":"Soerjomataram","year":"2008","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.ejca.2015.11.023_bib5","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s12957-014-0429-x","article-title":"Age at diagnosis in relation to survival following breast cancer: a cohort study","volume":"13","author":"Brandt","year":"2015","journal-title":"World J Surg Oncol"},{"key":"10.1016\/j.ejca.2015.11.023_bib6","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0895-4356(99)00165-1","article-title":"Organochlorine exposure and breast cancer survival","volume":"53","author":"H\u00f8yer","year":"2000","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.ejca.2015.11.023_bib7","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1471-2407-1-8","article-title":"Organochlorine exposures influence on breast cancer risk and survival according to estrogen receptor status: a Danish cohort-nested case-control study","volume":"1","author":"H\u00f8yer","year":"2001","journal-title":"BMC Cancer"},{"key":"10.1016\/j.ejca.2015.11.023_bib8","doi-asserted-by":"crossref","first-page":"e48","DOI":"10.5858\/134.7.e48","article-title":"American Society of Clinical Oncology\/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer (unabridged version)","volume":"134","author":"Hammond","year":"2010","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.ejca.2015.11.023_bib9","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1289\/ehp.1002211","article-title":"Intrinsic human elimination half-lives of polychlorinated biphenyls derived from the temporal evolution of cross-sectional biomonitoring data from the United Kingdom","volume":"119","author":"Ritter","year":"2011","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.ejca.2015.11.023_bib10","doi-asserted-by":"crossref","first-page":"5039","DOI":"10.1158\/0008-5472.SABCS-5039","article-title":"Abundance and distribution of polychlorinated biphenyls (PCBs) in breast tissue","volume":"69","author":"Ellsworth","year":"2014","journal-title":"Cancer Res"},{"key":"10.1016\/j.ejca.2015.11.023_bib11","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0300-483X(00)00368-1","article-title":"Effect of highly bioaccumulated polychlorinated biphenyl congeners on estrogen and androgen receptor activity","volume":"158","author":"Bonefeld-J\u00f8rgensen","year":"2001","journal-title":"Toxicology"},{"key":"10.1016\/j.ejca.2015.11.023_bib12","first-page":"41","article-title":"Polychlorinated Biphenyls, Cytochrome P4501A1 Polymorphism, and Postmenopausal Breast Cancer Risk","volume":"8","author":"Moysich","year":"1999","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.ejca.2015.11.023_bib13","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.canlet.2012.11.041","article-title":"Polychlorinated biphenyls (PCBs) as initiating agents in hepatocellular carcinoma","volume":"334","author":"Ludewig","year":"2012","journal-title":"Cancer Lett"},{"key":"10.1016\/j.ejca.2015.11.023_bib14","unstructured":"US Environmental Protection Agency. Polychlorinated Biphenyls (PCBs) 2013. http:\/\/www.epa.gov\/wastes\/hazard\/tsd\/pcbs\/about.htm (accessed March 3, 2015)."},{"key":"10.1016\/j.ejca.2015.11.023_bib15","doi-asserted-by":"crossref","first-page":"6109","DOI":"10.1016\/j.scitotenv.2009.08.035","article-title":"Background levels of polychlorinated biphenyls in the U.S. population","volume":"407","author":"Hopf","year":"2009","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.ejca.2015.11.023_bib16","unstructured":"Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological Profile for Polychlorinated Biphenyls (PCBs) 2015. http:\/\/www.atsdr.cdc.gov\/toxprofiles\/tp.asp?id=142&tid=26 (accessed March 5, 2015)."},{"key":"10.1016\/j.ejca.2015.11.023_bib17","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1093\/jnci\/85.8.648","article-title":"Blood levels of organochlorine residues and risk of breast cancer","volume":"85","author":"Wolff","year":"1993","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.ejca.2015.11.023_bib18","first-page":"1233","article-title":"Dichlorodiphenyldichloroethene, polychlorinated biphenyls, and breast cancer among African-American and white women in North Carolina","volume":"9","author":"Millikan","year":"2000","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.ejca.2015.11.023_bib19","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1023\/A:1008926219539","article-title":"Repeated measurements of organochlorine exposure and breast cancer risk (Denmark)","volume":"11","author":"H\u00f8yer","year":"2000","journal-title":"Cancer Causes Control"},{"key":"10.1016\/j.ejca.2015.11.023_bib20","first-page":"161","article-title":"Risk and aggressiveness of breast cancer in relation to plasma organochlorine concentrations","volume":"9","author":"Demers","year":"2000","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.ejca.2015.11.023_bib21","first-page":"55","article-title":"Breast adipose tissue concentrations of polychlorinated biphenyls and other organochlorines and breast cancer risk","volume":"9","author":"Aronson","year":"2000","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.ejca.2015.11.023_bib22","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1023\/A:1016387020854","article-title":"The Long Island Breast Cancer Study Project: description of a multi-institutional collaboration to identify environmental risk factors for breast cancer","volume":"74","author":"Gammon","year":"2002","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.ejca.2015.11.023_bib23","first-page":"686","article-title":"Environmental toxins and breast cancer on Long Island. II. Organochlorine compound levels in blood","volume":"11","author":"Gammon","year":"2002","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.ejca.2015.11.023_bib24","first-page":"467","article-title":"Treatment for breast cancer and blood levels of chlorinated hydrocarbons","volume":"5","author":"Gammon","year":"1996","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.ejca.2015.11.023_bib25","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1093\/jat\/20.7.528","article-title":"An improved analysis for chlorinated pesticides and polychlorinated biphenyls (PCBs) in human and bovine sera using solid-phase extraction","volume":"20","author":"Brock","year":"1996","journal-title":"J Anal Toxicol"},{"key":"10.1016\/j.ejca.2015.11.023_bib26","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/BF01055015","article-title":"Chlorinated hydrocarbon levels in human serum: effects of fasting and feeding","volume":"18","author":"Phillips","year":"1989","journal-title":"Arch Environ Contam Toxicol"},{"key":"10.1016\/j.ejca.2015.11.023_bib27","unstructured":"Centers for Disease Control and Prevention. National Death Index 2014. http:\/\/www.cdc.gov\/nchs\/ndi.htm."},{"key":"10.1016\/j.ejca.2015.11.023_bib28","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1289\/ehp.9710513","article-title":"Proposed PCB congener groupings for epidemiological studies","volume":"105","author":"Wolff","year":"1997","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.ejca.2015.11.023_bib29","unstructured":"Allison P. Survival Analysis Using SAS: A Practical Guide. 2nd ed. Cary, NC: 2010."},{"key":"10.1016\/j.ejca.2015.11.023_bib30","doi-asserted-by":"crossref","first-page":"2224","DOI":"10.1158\/1055-9965.EPI-05-0173","article-title":"Improving organochlorine biomarker models for cancer research","volume":"14","author":"Wolff","year":"2005","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.ejca.2015.11.023_bib31","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1097\/00001648-199901000-00008","article-title":"Causal diagrams for epidemiologic research","volume":"10","author":"Greenland","year":"1999","journal-title":"Epidemiology"},{"key":"10.1016\/j.ejca.2015.11.023_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/bcr1534","article-title":"Estrogenic microenvironment generated by organochlorine residues in adipose mammary tissue modulates biomarker expression in ER\u03b1-positive breast carcinomas","volume":"8","author":"Mu\u00f1oz-de-Toro","year":"2006","journal-title":"Breast Cancer Res"},{"key":"10.1016\/j.ejca.2015.11.023_bib33","doi-asserted-by":"crossref","first-page":"6151","DOI":"10.1007\/s00216-014-7922-5","article-title":"Analytical approaches for the determination of PCB metabolites in blood: a review","volume":"406","author":"Quinete","year":"2014","journal-title":"Anal Bioanal Chem"},{"key":"10.1016\/j.ejca.2015.11.023_bib34","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/S1047-2797(01)00285-X","article-title":"A primer and comparative review of major US mortality databases","volume":"12","author":"Cowper","year":"2002","journal-title":"Ann Epidemiol"},{"key":"10.1016\/j.ejca.2015.11.023_bib35","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1007\/s11606-013-2755-z","article-title":"Six persistent research misconceptions","volume":"29","author":"Rothman","year":"2014","journal-title":"J Gen Intern Med"},{"key":"10.1016\/j.ejca.2015.11.023_bib36","doi-asserted-by":"crossref","first-page":"242","DOI":"10.2105\/AJPH.71.3.242","article-title":"Accuracy of cancer death certificates and its effect on cancer mortality statistics","volume":"71","author":"Percy","year":"1981","journal-title":"Am J Public Health"},{"key":"10.1016\/j.ejca.2015.11.023_bib37","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/oem.52.8.557","article-title":"Non-differential misclassification and bias towards the null: a clarification","volume":"52","author":"Wacholder","year":"1995","journal-title":"Occup Env Med"}],"container-title":["European Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804915011314?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804915011314?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T19:49:20Z","timestamp":1654112960000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959804915011314"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":37,"alternative-id":["S0959804915011314"],"URL":"https:\/\/doi.org\/10.1016\/j.ejca.2015.11.023","relation":{},"ISSN":["0959-8049"],"issn-type":[{"value":"0959-8049","type":"print"}],"subject":[],"published":{"date-parts":[[2016,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Polychlorinated biphenyls and their association with survival following breast cancer","name":"articletitle","label":"Article Title"},{"value":"European Journal of Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejca.2015.11.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}