{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T14:39:12Z","timestamp":1789915152672,"version":"4.0.1"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","ejcancer.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Cancer"],"published-print":{"date-parts":[[2018,5]]},"DOI":"10.1016\/j.ejca.2018.02.029","type":"journal-article","created":{"date-parts":[[2018,3,28]],"date-time":"2018-03-28T11:10:35Z","timestamp":1522235435000},"page":"11-19","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Is alpha-fetoprotein decline a prognostic factor of childhood non-seminomatous germ cell tumours? Results of the French TGM95 study"],"prefix":"10.1016","volume":"95","author":[{"given":"B.","family":"Fresneau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2520-139X","authenticated-orcid":false,"given":"D.","family":"Orbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Faure-Conter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Sudour-Bonnange","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"V\u00e9rit\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Gandemer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Pasquet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Fasola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Rome","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Raimbault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Martelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Frappaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Le Teuff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Patte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejca.2018.02.029_bib1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/CEJ.0b013e32833876c0","article-title":"Incidence of childhood cancer in France: National children cancer registries, 2000\u20132004","volume":"19","author":"Lacour","year":"2010","journal-title":"Eur J Cancer Prev"},{"key":"10.1016\/j.ejca.2018.02.029_bib2","series-title":"SEER cancer statistics review","author":"Howlader","year":"1975"},{"key":"10.1016\/j.ejca.2018.02.029_bib3","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1200\/JCO.2014.58.3369","article-title":"Revised risk classification for pediatric extracranial germ cell tumors based on 25 years of clinical trial data from the United Kingdom and United States","volume":"33","author":"Frazier","year":"2015","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2018.02.029_bib4","doi-asserted-by":"crossref","first-page":"3868","DOI":"10.1200\/JCO.2004.04.008","article-title":"Early predicted time to normalization of tumor markers predicts outcome in poor-prognosis nonseminomatous germ cell tumors","volume":"22","author":"Fizazi","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2018.02.029_bib5","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1016\/S1470-2045(14)70490-5","article-title":"Personalised chemotherapy based on tumour marker decline in poor prognosis germ-cell tumours (GETUG 13): a phase 3, multicentre, randomised trial","volume":"15","author":"Fizazi","year":"2014","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ejca.2018.02.029_bib6","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1002\/mpo.2950210602","article-title":"Treatment of non-metastatic, non-seminomatous malignant germ-cell tumours in childhood: experience of the \u201cSoci\u00e9t\u00e9 Fran\u00e7aise d'Oncologie P\u00e9diatrique\u201d MGCT 1985-1989 study","volume":"21","author":"Baranzelli","year":"1993","journal-title":"Med Pediatr Oncol"},{"key":"10.1016\/j.ejca.2018.02.029_bib7","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1200\/JCO.1999.17.4.1212","article-title":"Prognostic factors in children with localized malignant nonseminomatous germ cell tumors","volume":"17","author":"Baranzelli","year":"1999","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2018.02.029_bib8","doi-asserted-by":"crossref","DOI":"10.1002\/pbc.25614","article-title":"Sex-cord stromal tumors in children and teenagers: results of the TGM-95 study","author":"Fresneau","year":"2015","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.ejca.2018.02.029_bib9","series-title":"WHO classification of tumours of female reproductive organs","year":"2014"},{"key":"10.1016\/j.ejca.2018.02.029_bib10","series-title":"WHO classification of tumours of the urinary system and male genital organs","year":"2016"},{"key":"10.1016\/j.ejca.2018.02.029_bib11","doi-asserted-by":"crossref","unstructured":"International germ cell Consensus classification: a prognostic factor-based staging system for metastatic germ cell cancers. International germ cell cancer collaborative group. J Clin Oncol Off J Am Soc Clin Oncol 1997;15:594\u2013603.","DOI":"10.1200\/JCO.1997.15.2.594"},{"key":"10.1016\/j.ejca.2018.02.029_bib12","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/j.0006-341X.2001.00114.x","article-title":"A solution to the problem of monotone likelihood in Cox regression","volume":"57","author":"Heinze","year":"2001","journal-title":"Biometrics"},{"key":"10.1016\/j.ejca.2018.02.029_bib13","doi-asserted-by":"crossref","first-page":"3809","DOI":"10.1200\/JCO.2000.18.22.3809","article-title":"The United Kingdom Children's Cancer Study Group's second germ cell tumor study: carboplatin, etoposide, and bleomycin are effective treatment for children with malignant extracranial germ cell tumors, with acceptable toxicity","volume":"18","author":"Mann","year":"2000","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2018.02.029_bib14","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1200\/JCO.2013.51.1006","article-title":"Surveillance after initial surgery for pediatric and adolescent girls with stage I ovarian germ cell tumors: report from the Children's Oncology Group","volume":"32","author":"Billmire","year":"2014","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2018.02.029_bib15","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.jpedsurg.2015.03.026","article-title":"Surveillance after initial surgery for stage I pediatric and adolescent boys with malignant testicular germ cell tumors: report from the Children's Oncology Group","volume":"50","author":"Rescorla","year":"2015","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.ejca.2018.02.029_bib16","doi-asserted-by":"crossref","first-page":"5350","DOI":"10.1200\/JCO.2008.17.5257","article-title":"Long-term evaluation of ifosfamide-related nephrotoxicity in children","volume":"27","author":"Oberlin","year":"2009","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2018.02.029_bib17","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1200\/JCO.2003.04.100","article-title":"Risk of secondary leukemia after a solid tumor in childhood according to the dose of epipodophyllotoxins and anthracyclines: a case-control study by the Soci\u00e9t\u00e9 Fran\u00e7aise d'Oncologie P\u00e9diatrique","volume":"21","author":"Le Deley","year":"2003","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2018.02.029_bib18","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1056\/NEJM198706043162302","article-title":"Treatment of disseminated germ-cell tumors with cisplatin, bleomycin, and either vinblastine or etoposide","volume":"316","author":"Williams","year":"1987","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejca.2018.02.029_bib19","doi-asserted-by":"crossref","first-page":"2691","DOI":"10.1200\/JCO.2004.08.015","volume":"22","author":"Cushing","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2018.02.029_bib20","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1200\/JCO.2008.16.4202","article-title":"Cisplatin and etoposide in childhood germ cell tumor: Brazilian pediatric oncology society protocol GCT-91","volume":"27","author":"Lopes","year":"2009","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2018.02.029_bib21","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1200\/JCO.2014.59.1420","article-title":"Lowered Cisplatin dose and No Bleomycin in the treatment of pediatric germ cell tumors: results of the GCT-99 protocol from the Brazilian germ cell pediatric oncology cooperative group","volume":"34","author":"Lopes","year":"2016","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2018.02.029_bib22","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1093\/annonc\/mdm062","article-title":"Refining the optimal chemotherapy regimen for good-risk metastatic nonseminomatous germ-cell tumors: a randomized trial of the Genito-Urinary Group of the French Federation of Cancer Centers (GETUG T93BP)","volume":"18","author":"Culine","year":"2007","journal-title":"Ann Oncol"},{"key":"10.1016\/j.ejca.2018.02.029_bib23","doi-asserted-by":"crossref","first-page":"3991","DOI":"10.1200\/JCO.2007.10.9777","article-title":"American Society of Clinical Oncology clinical evidence review on the ongoing care of adult cancer survivors: cardiac and pulmonary late effects","volume":"25","author":"Carver","year":"2007","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2018.02.029_bib24","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1002\/cncr.11271","article-title":"Cisplatin, etoposide and either bleomycin or ifosfamide in the treatment of disseminated germ cell tumors: final analysis of an intergroup trial","volume":"97","author":"Hinton","year":"2003","journal-title":"Cancer"},{"key":"10.1016\/j.ejca.2018.02.029_bib25","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1002\/pbc.24229","article-title":"Brain metastases during follow-up of children and adolescents with extracranial malignant germ cell tumors: risk adapted management decision tree analysis based on data of the MAHO\/MAKEI-registry","volume":"60","author":"G\u00f6bel","year":"2013","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.ejca.2018.02.029_bib26","doi-asserted-by":"crossref","first-page":"2544","DOI":"10.1200\/JCO.2005.04.1251","article-title":"Prognostic factors in children with extragonadal malignant germ cell tumors: a pediatric intergroup study","volume":"24","author":"Marina","year":"2006","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2018.02.029_bib27","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1200\/JCO.2005.05.4528","article-title":"Phase III randomized trial of conventional-dose chemotherapy with or without high-dose chemotherapy and autologous hematopoietic stem-cell rescue as first-line treatment for patients with poor-prognosis metastatic germ cell tumors","volume":"25","author":"Motzer","year":"2007","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2018.02.029_bib28","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1093\/annonc\/mds504","article-title":"Tumor marker kinetics predict outcome in patients with relapsed disseminated non-seminomatous germ-cell tumors","volume":"24","author":"Massard","year":"2013","journal-title":"Ann Oncol"}],"container-title":["European Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804918302375?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804918302375?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,10,13]],"date-time":"2019-10-13T12:32:51Z","timestamp":1570969971000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959804918302375"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5]]},"references-count":28,"alternative-id":["S0959804918302375"],"URL":"https:\/\/doi.org\/10.1016\/j.ejca.2018.02.029","relation":{},"ISSN":["0959-8049"],"issn-type":[{"value":"0959-8049","type":"print"}],"subject":[],"published":{"date-parts":[[2018,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Is alpha-fetoprotein decline a prognostic factor of childhood non-seminomatous germ cell tumours? Results of the French TGM95 study","name":"articletitle","label":"Article Title"},{"value":"European Journal of Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejca.2018.02.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}