{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T19:35:37Z","timestamp":1791228937954,"version":"4.1.0"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100013362","name":"Swiss Cancer Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013362","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004361","name":"Krebsliga Schweiz","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004361","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004963","name":"Seventh Framework Programme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004963","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejcancer.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Cancer"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1016\/j.ejca.2020.07.019","type":"journal-article","created":{"date-parts":[[2020,9,6]],"date-time":"2020-09-06T08:53:21Z","timestamp":1599382401000},"page":"212-224","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":45,"special_numbering":"C","title":["Usefulness of current candidate genetic markers to identify childhood cancer patients at risk for platinum-induced ototoxicity: Results of the European PanCareLIFE cohort study"],"prefix":"10.1016","volume":"138","author":[{"given":"Thorsten","family":"Langer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Clemens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Broer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lara","family":"Maier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9 G.","family":"Uitterlinden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrica C.H.","family":"de Vries","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martine","family":"van Grotel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saskia F.M.","family":"Pluijm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harald","family":"Binder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Mayer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annika","family":"von dem Knesebeck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julianne","family":"Byrne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8870-6539","authenticated-orcid":false,"given":"Eline","family":"van Dulmen-den Broeder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Crocco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Desiree","family":"Grabow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Kaatsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Kaiser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Spix","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3584-6570","authenticated-orcid":false,"given":"Line","family":"Kenborg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanette F.","family":"Winther","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Rechnitzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Hasle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Kepak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne-Lotte F.","family":"van der Kooi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leontien C.","family":"Kremer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jarmila","family":"Kruseova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Bielack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Sorg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"Hecker-Nolting","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia E.","family":"Kuehni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Ansari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Kompis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heleen","family":"van der Pal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ross","family":"Parfitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk","family":"Deuster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Matulat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amelie","family":"Tillmanns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wim J.E.","family":"Tissing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rn D.","family":"Beck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Elsner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoinette","family":"am Zehnhoff-Dinnesen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marry M.","family":"van den Heuvel-Eibrink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Zolk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejca.2020.07.019_bib1","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.tips.2013.05.006","article-title":"Understanding platinum-induced ototoxicity","volume":"34","author":"Langer","year":"2013","journal-title":"Trends Pharmacol Sci"},{"key":"10.1016\/j.ejca.2020.07.019_bib2","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.critrevonc.2018.04.001","article-title":"The influence of genetic variation on late toxicities in childhood cancer survivors: a review","volume":"126","author":"Clemens","year":"2018","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.1016\/j.ejca.2020.07.019_bib3","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1038\/ng.478","article-title":"Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy","volume":"41","author":"Ross","year":"2009","journal-title":"Nat Genet"},{"key":"10.1016\/j.ejca.2020.07.019_bib4","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1200\/JCO.2006.08.9599","article-title":"Cisplatin-induced long-term hearing impairment is associated with specific glutathione s-transferase genotypes in testicular cancer survivors","volume":"25","author":"Oldenburg","year":"2007","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2020.07.019_bib5","doi-asserted-by":"crossref","first-page":"323","DOI":"10.2217\/pgs.14.182","article-title":"Human OCT2 variant c.808G>T confers protection effect against cisplatin-induced ototoxicity","volume":"16","author":"Lanvers-Kaminsky","year":"2015","journal-title":"Pharmacogenomics"},{"issue":"11","key":"10.1016\/j.ejca.2020.07.019_bib6","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1001\/jamaoncol.2017.0502","article-title":"Association between SLC16A5 genetic variation and cisplatin-induced ototoxic effects in adult patients with testicular cancer","volume":"3","author":"Dr\u00f6gem\u00f6ller","year":"2017","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.ejca.2020.07.019_bib7","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/sj.tpj.6500455","article-title":"Megalin genetic polymorphisms and individual sensitivity to the ototoxic effect of cisplatin","volume":"8","author":"Riedemann","year":"2008","journal-title":"Pharmacogenomics J"},{"key":"10.1016\/j.ejca.2020.07.019_bib8","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1002\/cam4.516","article-title":"SOD2 genetic variant associated with treatment-related ototoxicity in cisplatin-treated pediatric medulloblastoma","volume":"4","author":"Brown","year":"2015","journal-title":"Cancer Med"},{"issue":"6","key":"10.1016\/j.ejca.2020.07.019_bib9","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/tpj.2016.52","article-title":"Promoter region variation in NFE2L2 influences susceptibility to ototoxicity in patients exposed to high cumulative doses of cisplatin","volume":"17","author":"Spracklen","year":"2016","journal-title":"Pharmacogenomics J"},{"key":"10.1016\/j.ejca.2020.07.019_bib10","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.2217\/pgs.14.112","article-title":"Genetic variation in Otos is associated with cisplatin-induced ototoxicity","volume":"15","author":"Spracklen","year":"2014","journal-title":"Pharmacogenomics"},{"key":"10.1016\/j.ejca.2020.07.019_bib11","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/ng.3217","article-title":"Common variants in ACYP2 influence susceptibility to cisplatin-induced hearing loss","volume":"47","author":"Xu","year":"2015","journal-title":"Nat Genet"},{"key":"10.1016\/j.ejca.2020.07.019_bib12","doi-asserted-by":"crossref","first-page":"3325","DOI":"10.1158\/1078-0432.CCR-16-2809","article-title":"Variants in WFS1 and other mendelian deafness genes are associated with cisplatin-associated ototoxicity","volume":"23","author":"Wheeler","year":"2017","journal-title":"Clin Canc Res"},{"key":"10.1016\/j.ejca.2020.07.019_bib13","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1158\/1078-0432.CCR-17-2810","article-title":"Further investigation of the role of ACYP2 and WFS1 pharmacogenomic variants in the development of cisplatin-induced ototoxicity in testicular cancer patients","volume":"24","author":"Drogemoller","year":"2018","journal-title":"Clin Canc Res"},{"key":"10.1016\/j.ejca.2020.07.019_bib14","series-title":"Cisplatin injection","author":"Prescribing information","year":"2019"},{"key":"10.1016\/j.ejca.2020.07.019_bib15","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1097\/FTD.0000000000000298","article-title":"Clinical practice recommendations for the management and prevention of cisplatin-induced hearing loss using pharmacogenetic markers","volume":"38","author":"Lee","year":"2016","journal-title":"Ther Drug Monit"},{"key":"10.1016\/j.ejca.2020.07.019_bib16","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.ejca.2018.08.007","article-title":"PanCareLIFE: the scientific basis for a European project to improve long-term care regarding fertility, ototoxicity and health-related quality of life after cancer occurring among children and adolescents","volume":"103","author":"Byrne","year":"2018","journal-title":"Eur J Canc"},{"issue":"2","key":"10.1016\/j.ejca.2020.07.019_bib17","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1038\/s41397-019-0113-1","article-title":"Genetic variation of cisplatin-induced ototoxicity in non-cranial-irradiated pediatric patients using a candidate gene approach: the International PanCareLIFE Study","volume":"20","author":"Clemens","year":"2019","journal-title":"Pharmacogenomics J"},{"key":"10.1016\/j.ejca.2020.07.019_bib18","doi-asserted-by":"crossref","DOI":"10.2196\/11868","article-title":"Genetic determinants of ototoxicity during and after childhood cancer treatment: protocol for the PanCareLIFE study","volume":"8","author":"Clemens","year":"2019","journal-title":"JMIR Res Protoc"},{"key":"10.1016\/j.ejca.2020.07.019_bib19","doi-asserted-by":"crossref","first-page":"655","DOI":"10.3109\/0284186X.2015.1008648","article-title":"Childhood cancer survivor cohorts in Europe","volume":"54","author":"Winther","year":"2015","journal-title":"Acta Oncol"},{"key":"10.1016\/j.ejca.2020.07.019_bib20","first-page":"1","article-title":"The societal costs of severe to profound hearing loss in the United States","volume":"2","author":"Mohr","year":"2000","journal-title":"Policy Anal Brief H Serv"},{"key":"10.1016\/j.ejca.2020.07.019_bib21","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1002\/cpt.1483","article-title":"Pharmacogenomics of cisplatin-induced ototoxicity: successes, shortcomings, and future avenues of research","volume":"106","author":"Drogemoller","year":"2019","journal-title":"Clin Pharmacol Ther"},{"key":"10.1016\/j.ejca.2020.07.019_bib22","doi-asserted-by":"crossref","first-page":"E320","DOI":"10.1002\/lary.25304","article-title":"Immunohistochemical localization of OCT2 in the cochlea of various species","volume":"125","author":"Hellberg","year":"2015","journal-title":"Laryngoscope"},{"key":"10.1016\/j.ejca.2020.07.019_bib23","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1124\/jpet.106.110346","article-title":"Cisplatin and oxaliplatin, but not carboplatin and nedaplatin, are substrates for human organic cation transporters (SLC22A1-3 and multidrug and toxin extrusion family)","volume":"319","author":"Yonezawa","year":"2006","journal-title":"J Pharmacol Exp Therapeut"},{"key":"10.1016\/j.ejca.2020.07.019_bib24","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.2353\/ajpath.2010.090610","article-title":"Organic cation transporter 2 mediates cisplatin-induced oto- and nephrotoxicity and is a target for protective interventions","volume":"176","author":"Ciarimboli","year":"2010","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ejca.2020.07.019_bib25","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1124\/dmd.108.023762","article-title":"Functional characterization of the human organic cation transporter 2 variant p.270Ala>Ser","volume":"37","author":"Zolk","year":"2009","journal-title":"Drug Metab Dispos."},{"key":"10.1016\/j.ejca.2020.07.019_bib26","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0175711","article-title":"Pharmacogenetic variants in TPMT alter cellular responses to cisplatin in inner ear cell lines","volume":"12","author":"Bhavsar","year":"2017","journal-title":"PloS One"},{"key":"10.1016\/j.ejca.2020.07.019_bib27","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.oraloncology.2018.12.010","article-title":"Predictors of cisplatin-induced ototoxicity and survival in chemoradiation treated head and neck cancer patients","volume":"89","author":"Teft","year":"2019","journal-title":"Oral Oncol"},{"key":"10.1016\/j.ejca.2020.07.019_bib28","doi-asserted-by":"crossref","first-page":"60","DOI":"10.17116\/otorino201883460","article-title":"[The analysis of the association of the polymorphic variants of the TPMT, COMT, and ABCC3 genes with the development of hearing disorders induced by the cisplatin treatment]","volume":"83","author":"Mironovich","year":"2018","journal-title":"Vestn Otorinolaringol"},{"key":"10.1016\/j.ejca.2020.07.019_bib29","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1038\/clpt.2014.92","article-title":"Genetic markers of cisplatin-induced hearing loss in children","volume":"96","author":"Carleton","year":"2014","journal-title":"Clin Pharmacol Ther"},{"key":"10.1016\/j.ejca.2020.07.019_bib30","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1038\/clpt.2013.219","article-title":"Role of TPMT and COMT genetic variation in cisplatin-induced ototoxicity","volume":"95","author":"Carleton","year":"2014","journal-title":"Clin Pharmacol Ther"},{"key":"10.1016\/j.ejca.2020.07.019_bib31","doi-asserted-by":"crossref","DOI":"10.3390\/cancers11040551","article-title":"Genetic variants as predictive markers for ototoxicity and nephrotoxicity in patients with locally advanced head and neck cancer treated with cisplatin-containing chemoradiotherapy (the PRONE study)","volume":"11","author":"Driessen","year":"2019","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.ejca.2020.07.019_bib32","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0115869","article-title":"Influence of genetic variants in TPMT and COMT associated with cisplatin induced hearing loss in patients with cancer: two new cohorts and a meta-analysis reveal significant heterogeneity between cohorts","volume":"9","author":"Hagleitner","year":"2014","journal-title":"PloS One"},{"key":"10.1016\/j.ejca.2020.07.019_bib33","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1038\/clpt.2013.121","article-title":"The role of inherited TPMT and COMT genetic variation in cisplatin-induced ototoxicity in children with cancer","volume":"94","author":"Yang","year":"2013","journal-title":"Clin Pharmacol Ther"},{"key":"10.1016\/j.ejca.2020.07.019_bib34","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.ijporl.2016.09.001","article-title":"Analysis of genetic and non genetic risk factors for cisplatin ototoxicity in pediatric patients","volume":"90","author":"Olgun","year":"2016","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.1016\/j.ejca.2020.07.019_bib35","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1097\/FPC.0000000000000281","article-title":"TPMT, COMT and ACYP2 genetic variants in paediatric cancer patients with cisplatin-induced ototoxicity","volume":"27","author":"Thiesen","year":"2017","journal-title":"Pharmacogenetics Genom"},{"key":"10.1016\/j.ejca.2020.07.019_bib36","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1006916","article-title":"Statistical correction of the Winner's Curse explains replication variability in quantitative trait genome-wide association studies","volume":"13","author":"Palmer","year":"2017","journal-title":"PLoS Genet"},{"key":"10.1016\/j.ejca.2020.07.019_bib37","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1038\/clpt.2013.178","article-title":"Challenges in interpreting the evidence for genetic predictors of ototoxicity","volume":"94","author":"Ratain","year":"2013","journal-title":"Clin Pharmacol Ther"},{"key":"10.1016\/j.ejca.2020.07.019_bib38","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s00106-005-1368-1","article-title":"The \u201cMuenster classification\u201d of high frequency hearing loss following cisplatin chemotherapy","volume":"55","author":"Schmidt","year":"2007","journal-title":"HNO"},{"key":"10.1016\/j.ejca.2020.07.019_bib39","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/pbc.24307","article-title":"Early cisplatin induced ototoxicity profile may predict the need for hearing support in children with medulloblastoma","volume":"60","author":"Lafay-Cousin","year":"2013","journal-title":"Pediatr Blood Canc"},{"key":"10.1016\/j.ejca.2020.07.019_bib40","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0210646","article-title":"A comparison of the Muenster, SIOP Boston, Brock, Chang and CTCAEv4.03 ototoxicity grading scales applied to 3,799 audiograms of childhood cancer patients treated with platinum-based chemotherapy","volume":"14","author":"Clemens","year":"2019","journal-title":"PloS One"},{"key":"10.1016\/j.ejca.2020.07.019_bib41","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1007\/s00405-016-4117-z","article-title":"Platinum-induced ototoxicity: a review of prevailing ototoxicity criteria","volume":"274","author":"Waissbluth","year":"2017","journal-title":"Eur Arch Oto-Rhino-Laryngol"},{"key":"10.1016\/j.ejca.2020.07.019_bib42","doi-asserted-by":"crossref","first-page":"4353","DOI":"10.1158\/0008-5472.CAN-04-0340","article-title":"Heritability and linkage analysis of sensitivity to cisplatin-induced cytotoxicity","volume":"64","author":"Dolan","year":"2004","journal-title":"Canc Res"},{"key":"10.1016\/j.ejca.2020.07.019_bib43","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1038\/clpt.2013.80","article-title":"Replication of TPMT and ABCC3 genetic variants highly associated with cisplatin-induced hearing loss in children","volume":"94","author":"Pussegoda","year":"2013","journal-title":"Clin Pharmacol Ther"},{"key":"10.1016\/j.ejca.2020.07.019_bib44","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1038\/clpt.2014.67","article-title":"Evaluation of pharmacogenetic markers to predict the risk of Cisplatin-induced ototoxicity","volume":"96","author":"Lanvers-Kaminsky","year":"2014","journal-title":"Clin Pharmacol Ther"}],"container-title":["European Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804920304184?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804920304184?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T20:29:28Z","timestamp":1760732968000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959804920304184"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":44,"alternative-id":["S0959804920304184"],"URL":"https:\/\/doi.org\/10.1016\/j.ejca.2020.07.019","relation":{},"ISSN":["0959-8049"],"issn-type":[{"value":"0959-8049","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Usefulness of current candidate genetic markers to identify childhood cancer patients at risk for platinum-induced ototoxicity: Results of the European PanCareLIFE cohort study","name":"articletitle","label":"Article Title"},{"value":"European Journal of Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejca.2020.07.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}