{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T01:15:50Z","timestamp":1773537350682,"version":"3.50.1"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100006244","name":"Children Cancer Free Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006244","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejcancer.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Cancer"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.ejca.2021.03.021","type":"journal-article","created":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T01:50:55Z","timestamp":1619747455000},"page":"240-249","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Clinical characteristics of subsequent histologically confirmed meningiomas in long-term childhood cancer survivors: A Dutch LATER study"],"prefix":"10.1016","volume":"150","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5677-4836","authenticated-orcid":false,"given":"Lisanne C.","family":"Verbruggen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith L.","family":"Kok","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2647-2677","authenticated-orcid":false,"given":"Jop C.","family":"Teepen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geert O.","family":"Janssens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte M.","family":"de Boer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lukas J.A.","family":"Stalpers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meike W.","family":"Vernooij","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8870-6539","authenticated-orcid":false,"given":"Eline","family":"van Dulmen-den Broeder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline J.","family":"Loonen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marry M.","family":"van den Heuvel-Eibrink","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wim J.E.","family":"Tissing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5767-854X","authenticated-orcid":false,"given":"Margriet","family":"van der Heiden-van der Loo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4283-5503","authenticated-orcid":false,"given":"Anne Birgitta","family":"Versluys","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian J.C.M.M.","family":"Neggers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flora E.","family":"van Leeuwen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eelco W.","family":"Hoving","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pieter","family":"Wesseling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leontine C.M.","family":"Kremer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9cile M.","family":"Ronckers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helena J.H.","family":"van der Pal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marloes","family":"Louwerens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrica","family":"de Vries","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monique","family":"Jaspers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nynke","family":"Hollema","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaap","family":"den Hartogh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Netteke","family":"Schouten-van Meeteren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejca.2021.03.021_bib1","doi-asserted-by":"crossref","first-page":"5287","DOI":"10.1200\/JCO.2009.27.0090","article-title":"Population-based risks of CNS tumors in survivors of childhood cancer: the British Childhood Cancer Survivor Study","volume":"28","author":"Taylor","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2021.03.021_bib2","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1093\/jnci\/djp148","article-title":"Long-term outcomes among adult survivors of childhood central nervous system malignancies in the childhood cancer survivor study","volume":"101","author":"Armstrong","year":"2009","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.ejca.2021.03.021_bib3","doi-asserted-by":"crossref","first-page":"e321","DOI":"10.1016\/S1470-2045(13)70107-4","article-title":"Subsequent neoplasms of the CNS among survivors of childhood cancer: a systematic review","volume":"14","author":"Bowers","year":"2013","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ejca.2021.03.021_bib4","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/s00401-016-1545-1","article-title":"The 2016 World Health Organization classification of tumors of the central nervous system: a summary","volume":"131","author":"Louis","year":"2016","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.ejca.2021.03.021_bib5","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/S1474-4422(06)70625-1","article-title":"Histological classification and molecular genetics of meningiomas","volume":"5","author":"Riemenschneider","year":"2006","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.ejca.2021.03.021_bib6","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1200\/JCO.2016.70.1896","article-title":"Morbidity and mortality associated with meningioma after cranial radiotherapy: a report from the childhood cancer survivor study","volume":"35","author":"Bowers","year":"2017","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2021.03.021_bib7","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.3171\/2015.4.JNS142742","article-title":"Seizures in supratentorial meningioma: a systematic review and meta-analysis","volume":"124","author":"Englot","year":"2016","journal-title":"J Neurosurg"},{"key":"10.1016\/j.ejca.2021.03.021_bib8","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.critrevonc.2008.01.010","article-title":"Meningioma","volume":"67","author":"Marosi","year":"2008","journal-title":"Crit Rev Oncol Hematol."},{"key":"10.1016\/j.ejca.2021.03.021_bib9","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1093\/neuonc\/nos013","article-title":"Impaired survival and long-term neurological problems in benign meningioma","volume":"14","author":"van Alkemade","year":"2012","journal-title":"Neuro Oncol"},{"key":"10.1016\/j.ejca.2021.03.021_bib10","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s11060-007-9366-7","article-title":"Differential effect of surgery and radiotherapy on neurocognitive functioning and health-related quality of life in WHO grade I meningioma patients","volume":"84","author":"van Nieuwenhuizen","year":"2007","journal-title":"J Neuro\u00a0Oncol"},{"key":"10.1016\/j.ejca.2021.03.021_bib11","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1227\/NEU.0b013e318212badb","article-title":"Long-term impact of cognitive deficits and epilepsy on quality of life in patients with low-grade meningiomas","volume":"69","author":"Waagemans","year":"2011","journal-title":"Neurosurgery"},{"key":"10.1016\/j.ejca.2021.03.021_bib12","doi-asserted-by":"crossref","first-page":"v1","DOI":"10.1093\/neuonc\/noz150","article-title":"CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2012-2016","volume":"21","author":"Ostrom","year":"2019","journal-title":"Neuro Oncol"},{"key":"10.1016\/j.ejca.2021.03.021_bib13","series-title":"Meningiomas: diagnosis, treatment, and outcome","author":"Lee","year":"2008"},{"key":"10.1016\/j.ejca.2021.03.021_bib14","first-page":"131962","article-title":"Multiple intracranial meningiomas: a review of the literature and a case report","volume":"2013","author":"Koech","year":"2013","journal-title":"Case Rep Surg"},{"key":"10.1016\/j.ejca.2021.03.021_bib15","first-page":"8","article-title":"Multiple meningiomas evaluated by computed tomography","volume":"30","author":"Locatelli","year":"1987","journal-title":"Neurochirurgia"},{"key":"10.1016\/j.ejca.2021.03.021_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/jns.1983.59.1.0001","article-title":"Multiple meningiomas: a long-term review","volume":"59","author":"Sheehy","year":"1983","journal-title":"J Neurosurg"},{"key":"10.1016\/j.ejca.2021.03.021_bib17","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1148\/radiol.2016160218","article-title":"Prevalence, clinical management, and natural course of incidental findings on brain MR images: the population-based rotterdam scan study","volume":"281","author":"Bos","year":"2016","journal-title":"Radiology"},{"key":"10.1016\/j.ejca.2021.03.021_bib18","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1215\/15228517-2008-122","article-title":"Radiation-induced meningiomas: a shadow in the success story of childhood leukemia","volume":"11","author":"Banerjee","year":"2009","journal-title":"Neuro Oncol"},{"key":"10.1016\/j.ejca.2021.03.021_bib19","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.3171\/jns.2002.97.5.1078","article-title":"Radiation-induced meningioma: a descriptive study of 253 cases","volume":"97","author":"Sadetzki","year":"2002","journal-title":"J Neurosurg"},{"key":"10.1016\/j.ejca.2021.03.021_bib20","doi-asserted-by":"crossref","first-page":"E7","DOI":"10.3171\/FOC\/2008\/24\/5\/E7","article-title":"Radiation-induced meningioma","volume":"24","author":"Umansky","year":"2008","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.ejca.2021.03.021_bib21","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.3171\/jns.2004.100.6.1002","article-title":"Radiation-induced meningiomas: clinical, pathological, cytokinetic, and cytogenetic characteristics","volume":"100","author":"Al-Mefty","year":"2004","journal-title":"J Neurosurg"},{"key":"10.1016\/j.ejca.2021.03.021_bib22","doi-asserted-by":"crossref","first-page":"5781","DOI":"10.1200\/JCO.2009.22.4386","article-title":"Survival after second primary neoplasms of the brain or spinal cord in survivors of childhood cancer: results from the British Childhood Cancer Survivor Study","volume":"27","author":"Taylor","year":"2009","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2021.03.021_bib23","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1093\/jnci\/djj411","article-title":"New primary neoplasms of the central nervous system in survivors of childhood cancer: a report from the Childhood Cancer Survivor Study","volume":"98","author":"Neglia","year":"2006","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.ejca.2021.03.021_bib24","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1093\/neuonc\/noy124","article-title":"Risk of benign meningioma after childhood cancer in the DCOG-LATER cohort: contributions of radiation dose, exposed cranial volume, and age","volume":"21","author":"Kok","year":"2019","journal-title":"Neuro Oncol"},{"key":"10.1016\/j.ejca.2021.03.021_bib25","first-page":"1277","article-title":"Meningiomas after cranial radiotherapy for childhood cancer: a single institution experience","volume":"141","author":"Felicetti","year":"2015","journal-title":"J Canc Res Clin\u00a0Oncol"},{"key":"10.1016\/j.ejca.2021.03.021_bib27","doi-asserted-by":"crossref","DOI":"10.1007\/s11060-020-03436-5","article-title":"Variations in screening and management practices for subsequent asymptomatic meningiomas in childhood, adolescent and young adult cancer survivors","author":"Verbruggen","year":"2020","journal-title":"J Neuro Oncol"},{"key":"10.1016\/j.ejca.2021.03.021_bib28","doi-asserted-by":"crossref","first-page":"2288","DOI":"10.1200\/JCO.2016.71.6902","article-title":"Long-term risk of subsequent malignant neoplasms after treatment of childhood cancer in the DCOG LATER study cohort: role of chemotherapy","volume":"35","author":"Teepen","year":"2017","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2021.03.021_bib29","first-page":"19","article-title":"Pathology databanking and biobanking in The Netherlands, a central role for PALGA, the nationwide histopathology and cytopathology data network and archive","volume":"29","author":"Casparie","year":"2007","journal-title":"Cell Oncol"},{"key":"10.1016\/j.ejca.2021.03.021_bib30","series-title":"International classification of diseases for oncology: ICD-O","author":"Jack","year":"2000"},{"key":"10.1016\/j.ejca.2021.03.021_bib31","series-title":"Castor electronic data capture","year":"2019"},{"key":"10.1016\/j.ejca.2021.03.021_bib32","series-title":"IBM SPSS statistics for windows, version 25.0","year":"2013"},{"key":"10.1016\/j.ejca.2021.03.021_bib33","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1002\/pbc.21153","article-title":"High incidence of meningioma in cranial irradiated survivors of childhood acute lymphoblastic leukemia","volume":"49","author":"Goshen","year":"2007","journal-title":"Pediatr Blood Canc"},{"key":"10.1016\/j.ejca.2021.03.021_bib34","doi-asserted-by":"crossref","first-page":"3761","DOI":"10.1200\/JCO.1998.16.12.3761","article-title":"Secondary brain tumors in children treated for acute lymphoblastic leukemia at St Jude Children's Research Hospital","volume":"16","author":"Walter","year":"1998","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2021.03.021_bib35","doi-asserted-by":"crossref","first-page":"3568","DOI":"10.1200\/JCO.2015.60.9487","article-title":"Risk of subsequent neoplasms during the fifth and sixth decades of life in the childhood cancer survivor study cohort","volume":"33","author":"Turcotte","year":"2015","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2021.03.021_bib36","series-title":"Richtlijn follow-up na kinderkanker meer dan 5 jaar na diagnose","year":"2010"},{"key":"10.1016\/j.ejca.2021.03.021_bib37","doi-asserted-by":"crossref","DOI":"10.1177\/2054270414524567","article-title":"Meningiomas occurring during long-term survival after treatment for childhood cancer","volume":"5","author":"Sugden","year":"2014","journal-title":"JRSM Open"},{"key":"10.1016\/j.ejca.2021.03.021_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/S1470-2045(20)30688-4","article-title":"Surveillance for subsequent neoplasms of the CNS for childhood, adolescent, and young adult cancer survivors: a systematic review and recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group","author":"Bowers","year":"2021","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ejca.2021.03.021_bib39","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s00401-019-02008-w","article-title":"Mutational patterns and regulatory networks in epigenetic subgroups of meningioma","volume":"138","author":"Paramasivam","year":"2019","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.ejca.2021.03.021_bib40","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/S1470-2045(17)30155-9","article-title":"DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis","volume":"18","author":"Sahm","year":"2017","journal-title":"Lancet Oncol"}],"container-title":["European Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095980492100188X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095980492100188X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T20:32:06Z","timestamp":1760733126000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S095980492100188X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":39,"alternative-id":["S095980492100188X"],"URL":"https:\/\/doi.org\/10.1016\/j.ejca.2021.03.021","relation":{},"ISSN":["0959-8049"],"issn-type":[{"value":"0959-8049","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical characteristics of subsequent histologically confirmed meningiomas in long-term childhood cancer survivors: A Dutch LATER study","name":"articletitle","label":"Article Title"},{"value":"European Journal of Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejca.2021.03.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}