{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T02:12:10Z","timestamp":1790647930923,"version":"4.1.0"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,4,28]],"date-time":"2021-04-28T00:00:00Z","timestamp":1619568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000269","name":"Economic and Social Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejcancer.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Cancer"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1016\/j.ejca.2021.04.019","type":"journal-article","created":{"date-parts":[[2021,5,5]],"date-time":"2021-05-05T12:47:33Z","timestamp":1620218853000},"page":"233-242","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":60,"special_numbering":"C","title":["Economic impact of avoidable cancer deaths caused by diagnostic delay during the COVID-19 pandemic: A national population-based modelling study in England, UK"],"prefix":"10.1016","volume":"152","author":[{"given":"Adrian","family":"Gheorghe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camille","family":"Maringe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Spice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnie","family":"Purushotham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalipso","family":"Chalkidou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5837-7773","authenticated-orcid":false,"given":"Bernard","family":"Rachet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Sullivan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Aggarwal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejca.2021.04.019_bib1","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1038\/s41416-020-01182-z","article-title":"The COVID-19 pandemic and impact on breast cancer diagnoses: what happened in England in the first half of 2020","volume":"124","author":"Gathani","year":"2020","journal-title":"Br J Canc"},{"key":"10.1016\/j.ejca.2021.04.019_bib2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1038\/s41571-020-00446-0","article-title":"Consequences of COVID-19 for cancer care \u2014 a CRUK perspective","volume":"18","author":"Greenwood","year":"2021","journal-title":"Nat Rev Clin Oncol"},{"key":"10.1016\/j.ejca.2021.04.019_bib3","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1136\/gutjnl-2020-322179","article-title":"Impact of the COVID-19 pandemic on UK endoscopic activity and cancer detection: a National Endoscopy Database Analysis","volume":"70","author":"Rutter","year":"2020","journal-title":"Gut"},{"key":"10.1016\/j.ejca.2021.04.019_bib4","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1038\/s41416-021-01276-2","article-title":"Early cancer diagnosis: reaching targets across whole populations amidst setbacks","volume":"124","author":"McCormack","year":"2021","journal-title":"Br J Canc"},{"key":"10.1016\/j.ejca.2021.04.019_bib5","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.3332\/ecancer.2021.1180","article-title":"The impact of national non-pharmaceutical interventions (\u201clockdowns\u201d) on the presentation of cancer patients","volume":"15","author":"Purushotham","year":"2021","journal-title":"Ecancermedicalscience"},{"key":"10.1016\/j.ejca.2021.04.019_bib6","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S1470-2045(20)30743-9","article-title":"The impact of the COVID-19 pandemic on radiotherapy services in England, UK: a population-based study","volume":"22","author":"Spencer","year":"2021","journal-title":"Lancet Oncol"},{"issue":"3","key":"10.1016\/j.ejca.2021.04.019_bib7","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S2468-1253(21)00005-4","article-title":"Impact of the COVID-19 pandemic on the detection and management of colorectal cancer in England: a population-based study","volume":"6","author":"Morris","year":"2021","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"10.1016\/j.ejca.2021.04.019_bib8","first-page":"1","article-title":"The impact of the first peak of the COVID-19 pandemic on colorectal services in England and Wales; a national survey","author":"Boyle","year":"2021","journal-title":"Colorectal Dis"},{"issue":"8","key":"10.1016\/j.ejca.2021.04.019_bib9","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1038\/bjc.2012.408","article-title":"Routes to diagnosis for cancer - determining the patient journey using multiple routine data sets","volume":"107","author":"Elliss-Brookes","year":"2012","journal-title":"Br J Canc"},{"key":"10.1016\/j.ejca.2021.04.019_bib10","first-page":"4","article-title":"Cancer surgery delays are biggest concern as services struglle with COVID, say NHS Chief","author":"Donnelly","year":"2021","journal-title":"The Telegraph"},{"key":"10.1016\/j.ejca.2021.04.019_bib11","doi-asserted-by":"crossref","first-page":"m4087","DOI":"10.1136\/bmj.m4087","article-title":"Mortality due to cancer treatment delay: systematic review and meta-analysis","volume":"371","author":"Hanna","year":"2020","journal-title":"BMJ"},{"key":"10.1016\/j.ejca.2021.04.019_bib12","series-title":"Cancer Costs: a \u2018ripple effect\u2019 analysis of cancer's wider impact","author":"Hilhorst","year":"2019"},{"issue":"7","key":"10.1016\/j.ejca.2021.04.019_bib13","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/S1470-2045(19)30308-0","article-title":"Scale-up of radiotherapy for cervical cancer in the era of human papillomavirus vaccination in low-income and middle-income countries: a model-based analysis of need and economic impact","volume":"20","author":"Rodin","year":"2019","journal-title":"Lancet Oncol"},{"issue":"8","key":"10.1016\/j.ejca.2021.04.019_bib14","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S1470-2045(20)30388-0","article-title":"The impact of the COVID-19 pandemic on cancer deaths due to delays in diagnosis in England, UK: a national, population-based, modelling study","volume":"21","author":"Maringe","year":"2020","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ejca.2021.04.019_bib15","series-title":"Deaths registered weekly in England and Wales, provisional","year":"2020"},{"key":"10.1016\/j.ejca.2021.04.019_bib16","series-title":"National life tables, UK","year":"2019"},{"key":"10.1016\/j.ejca.2021.04.019_bib17","series-title":"Population norms for the EQ-5D. Self-reported population health: an international perspective based on EQ-5D","author":"Janssen","year":"2014"},{"key":"10.1016\/j.ejca.2021.04.019_bib18","series-title":"State pension age hits 66 and set to rise further","year":"2020"},{"key":"10.1016\/j.ejca.2021.04.019_bib19","series-title":"Earnings and hours worked, age group","year":"2019"},{"key":"10.1016\/j.ejca.2021.04.019_bib20","series-title":"Employment, unemployment and economic inactivity for people aged 16 years and over and aged from 16 to 64 years (not seasonally adjusted)","year":"2020"},{"key":"10.1016\/j.ejca.2021.04.019_bib21","series-title":"Estimates of the population for the UK, England and Wales, Scotland and Northern Ireland","year":"2020"},{"key":"10.1016\/j.ejca.2021.04.019_bib22","series-title":"Moving beyond \u2018lives-saved\u2019 from COVID-19","author":"Briggs","year":"2020"},{"key":"10.1016\/j.ejca.2021.04.019_bib23","series-title":"Cancer mortality by age","year":"2019"},{"key":"10.1016\/j.ejca.2021.04.019_bib24","first-page":"1","article-title":"An inverse stage-shift model to estimate the excess mortality and health economic impact of delayed access to cancer services due to the COVID-19 pandemic","volume":"1","author":"Degeling","year":"2021","journal-title":"Asia Pac J Clin Oncol"},{"issue":"6","key":"10.1016\/j.ejca.2021.04.019_bib25","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1002\/hed.26187","article-title":"Potential impact of the COVID-19 pandemic on financial toxicity in cancer survivors","volume":"42","author":"Baddour","year":"2020","journal-title":"Head Neck"},{"key":"10.1016\/j.ejca.2021.04.019_bib26","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.3332\/ecancer.2020.1134","article-title":"Cancer and COVID-19: economic impact on households in Southeast Asia","volume":"14","author":"Kong","year":"2020","journal-title":"Ecancermedicalscience"},{"key":"10.1016\/j.ejca.2021.04.019_bib27","series-title":"DAEDALUS: an economic-epidemiological model to optimize economic activity while containing the SARS-CoV-2 pandemic","author":"Haw","year":"2020"},{"key":"10.1016\/j.ejca.2021.04.019_bib28","series-title":"Direct and indirect impacts of COVID-19 on excess deaths and morbidity: executive summary","year":"2020"},{"key":"10.1016\/j.ejca.2021.04.019_bib29","series-title":"Recognition and referral of suspected lung cancer in the UK during the COVID-19 pandemic","year":"2021"},{"key":"10.1016\/j.ejca.2021.04.019_bib30","first-page":"371","article-title":"Mortality due to cancer treatment delay: systematic review and meta-analysis","author":"Hanna","year":"2020","journal-title":"Br Med J"},{"issue":"8","key":"10.1016\/j.ejca.2021.04.019_bib31","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/j.annonc.2020.05.009","article-title":"Collateral damage: the impact on outcomes from cancer surgery of the COVID-19 pandemic","volume":"31","author":"Sud","year":"2020","journal-title":"Ann Oncol"},{"key":"10.1016\/j.ejca.2021.04.019_bib32","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.ejca.2021.02.015","article-title":"New cancer cases at the time of the sars-cov2 pandemic and related public health policies","volume":"150","author":"Kempf","year":"2021","journal-title":"Eur J Canc"},{"key":"10.1016\/j.ejca.2021.04.019_bib33","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/S1470-2045(20)30265-5","article-title":"Fewer cancer diagnoses during the cancer epidemic in The Netherlands","volume":"21","author":"Din Mohamed","year":"2020","journal-title":"Lancet Oncol"},{"issue":"10045","key":"10.1016\/j.ejca.2021.04.019_bib34","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/S0140-6736(16)00577-8","article-title":"Economic downturns, universal health coverage, and cancer mortality in high-income and middle-income countries, 1990-2010: a longitudinal analysis","volume":"388","author":"Maruthappu","year":"2016","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.ejca.2021.04.019_bib35","doi-asserted-by":"crossref","unstructured":"De Angelis R, Sant M, Coleman M. Cancer survival in Europe 1999-2007 by country and age: results of EUROCARE-5 \u2013 a population-based study. Lancet Oncol;15(1):23-34.","DOI":"10.1016\/S1470-2045(13)70546-1"},{"issue":"11","key":"10.1016\/j.ejca.2021.04.019_bib36","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0207993","article-title":"Global treatment costs of breast cancer by stage: a systematic review","volume":"13","author":"Sun","year":"2018","journal-title":"PloS One"},{"issue":"12","key":"10.1016\/j.ejca.2021.04.019_bib37","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/S1470-2045(13)70442-X","article-title":"Economic burden of cancer across the European Union: a population-based cost analysis","volume":"14","author":"Luengo-Fernandez","year":"2013","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ejca.2021.04.019_bib38","series-title":"GBD compare","year":"2021"},{"issue":"2","key":"10.1016\/j.ejca.2021.04.019_bib39","doi-asserted-by":"crossref","DOI":"10.1136\/openhrt-2020-001359","article-title":"The impact of the COVID-19 pandemic on cardiology services","volume":"7","author":"Fersia","year":"2020","journal-title":"Open Heart"}],"container-title":["European Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804921002501?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804921002501?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T20:33:17Z","timestamp":1760733197000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959804921002501"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":39,"alternative-id":["S0959804921002501"],"URL":"https:\/\/doi.org\/10.1016\/j.ejca.2021.04.019","relation":{},"ISSN":["0959-8049"],"issn-type":[{"value":"0959-8049","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Economic impact of avoidable cancer deaths caused by diagnostic delay during the COVID-19 pandemic: A national population-based modelling study in England, UK","name":"articletitle","label":"Article Title"},{"value":"European Journal of Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejca.2021.04.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}