{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T21:34:12Z","timestamp":1783632852098,"version":"3.55.0"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100014382","name":"Ipsen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014382","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejcancer.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Cancer"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.ejca.2022.03.007","type":"journal-article","created":{"date-parts":[[2022,4,23]],"date-time":"2022-04-23T10:54:16Z","timestamp":1650711256000},"page":"80-90","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"special_numbering":"C","title":["The European Neuroendocrine Tumour Society registry, a tool to assess the prognosis of neuroendocrine neoplasms"],"prefix":"10.1016","volume":"168","author":[{"given":"Ivan","family":"Borbath","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3342-397X","authenticated-orcid":false,"given":"Rocio","family":"Garcia-Carbonero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damir","family":"Bikmukhametov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Jimenez-Fonseca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angel","family":"Casta\u00f1o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1406-7292","authenticated-orcid":false,"given":"Jaroslava","family":"Barkmanova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Sedlackova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Attila","family":"Koll\u00e1r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuel","family":"Christ","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5876-7883","authenticated-orcid":false,"given":"Gregory","family":"Kaltsas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beata","family":"Kos-Kudla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Maasberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Verslype","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich-Frank","family":"Pape","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.ejca.2022.03.007_bib1","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1001\/jamaoncol.2017.0589","article-title":"Trends in the incidence, prevalence, and survival outcomes in patients with neuroendocrine tumors in the United States","volume":"3","author":"Dasari","year":"2017","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.ejca.2022.03.007_bib2","unstructured":"SEER. (https:\/\/seer.cancer.gov\/)."},{"issue":"11","key":"10.1016\/j.ejca.2022.03.007_bib3","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1016\/j.ejca.2013.02.029","article-title":"Rare neuroendocrine tumours: results of the surveillance of rare cancers in Europe project","volume":"49","author":"van der Zwan","year":"2013","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ejca.2022.03.007_bib4","unstructured":"ENETS. www.enets.org."},{"issue":"2","key":"10.1016\/j.ejca.2022.03.007_bib5","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1159\/000443169","article-title":"ENETS 2016 consensus guidelines for the management of patients with digestive neuroendocrine tumors: an update","volume":"103","author":"O'Toole","year":"2016","journal-title":"Neuroendocrinology"},{"issue":"2","key":"10.1016\/j.ejca.2022.03.007_bib6","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1159\/000355152","article-title":"Prognostic factors and long-term outcome of pancreatic neuroendocrine neoplasms: Ki-67 index shows a greater impact on survival than disease stage. The large experience of the Spanish National Tumor Registry (RGETNE)","volume":"98","author":"Martin-Perez","year":"2013","journal-title":"Neuroendocrinology"},{"issue":"28","key":"10.1016\/j.ejca.2022.03.007_bib7","doi-asserted-by":"crossref","first-page":"2571","DOI":"10.1200\/JCO.19.00980","article-title":"Prediction of progression-free survival in patients with advanced, well-differentiated, neuroendocrine tumors being treated with a somatostatin analog: the GETNE-TRASGU study","volume":"37","author":"Carmona-Bayonas","year":"2019","journal-title":"J Clin Oncol"},{"issue":"4","key":"10.1016\/j.ejca.2022.03.007_bib8","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1634\/theoncologist.2017-0364","article-title":"Neuroendocrine tumor heterogeneity adds uncertainty to the world health organization 2010 classification: real-world data from the Spanish tumor registry (R-GETNE)","volume":"23","author":"Nunez-Valdovinos","year":"2018","journal-title":"Oncol"},{"issue":"9","key":"10.1016\/j.ejca.2022.03.007_bib9","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1093\/annonc\/mdq022","article-title":"Incidence, patterns of care and prognostic factors for outcome of gastroenteropancreatic neuroendocrine tumors (GEP-NETs): results from the National Cancer Registry of Spain (RGETNE)","volume":"21","author":"Garcia-Carbonero","year":"2010","journal-title":"Ann Oncol"},{"key":"10.1016\/j.ejca.2022.03.007_bib10","doi-asserted-by":"crossref","first-page":"w14362","DOI":"10.4414\/smw.2016.14362","article-title":"Additional malignancies in patients with neuroendocrine tumours: analysis of the SwissNET registry","volume":"146","author":"Kollar","year":"2016","journal-title":"Swiss Med Wkly"},{"key":"10.1016\/j.ejca.2022.03.007_bib11","doi-asserted-by":"crossref","first-page":"w20176","DOI":"10.4414\/smw.2020.20176","article-title":"Treatment sequence in patients with neuroendocrine tumours: a nationwide multicentre, observational analysis of the Swiss neuroendocrine tumour registry","volume":"150","author":"Kollar","year":"2020","journal-title":"Swiss Med Wkly"},{"issue":"1","key":"10.1016\/j.ejca.2022.03.007_bib12","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1530\/EC-17-0271","article-title":"Nationwide multicenter study on the management of pulmonary neuroendocrine (carcinoid) tumors","volume":"7","author":"Sadowski","year":"2018","journal-title":"Endocr Connect"},{"key":"10.1016\/j.ejca.2022.03.007_bib13","doi-asserted-by":"crossref","first-page":"w13924","DOI":"10.4414\/smw.2014.13924","article-title":"Diagnosis and workup of 522 consecutive patients with neuroendocrine neoplasms in Switzerland","volume":"144","author":"Gouffon","year":"2014","journal-title":"Swiss Med Wkly"},{"issue":"4","key":"10.1016\/j.ejca.2022.03.007_bib14","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1159\/000242109","article-title":"The German NET-registry: an audit on the diagnosis and therapy of neuroendocrine tumors","volume":"90","author":"Ploeckinger","year":"2009","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.ejca.2022.03.007_bib15","doi-asserted-by":"crossref","DOI":"10.1007\/s00423-020-01868-1","article-title":"Long-term outcome of surgical resection in patients with gastroenteropancreatic neuroendocrine neoplasia: results from a German nation-wide multi-centric registry","author":"Begum","year":"2020","journal-title":"Langenbeck's Arch Surg"},{"issue":"10","key":"10.1016\/j.ejca.2022.03.007_bib16","first-page":"1237","article-title":"Im namen aller teilnehmer\/innen am deutschen NETR, authors, kollaboratoren. [Neuroendocrine neoplasia within the German NET registry]","volume":"56","year":"2018","journal-title":"Z Gastroenterol"},{"key":"10.1016\/j.ejca.2022.03.007_bib17","article-title":"Predictive and prognostic factors for treatment and survival in 305 patients with advanced gastrointestinal neuroendocrine carcinoma (WHO G3): the NORDIC NEC study","author":"Sorbye","year":"2012","journal-title":"Ann Oncol"},{"key":"10.1016\/j.ejca.2022.03.007_bib18","series-title":"TNM supplement A commentary on uniform use","author":"Wittekind","year":"2019"},{"issue":"1","key":"10.1016\/j.ejca.2022.03.007_bib19","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1159\/000493318","article-title":"Unmet needs in high-grade gastroenteropancreatic neuroendocrine neoplasms (WHO G3)","volume":"108","author":"Sorbye","year":"2019","journal-title":"Neuroendocrinology"}],"container-title":["European Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804922001472?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804922001472?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T20:35:41Z","timestamp":1760733341000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959804922001472"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":19,"alternative-id":["S0959804922001472"],"URL":"https:\/\/doi.org\/10.1016\/j.ejca.2022.03.007","relation":{},"ISSN":["0959-8049"],"issn-type":[{"value":"0959-8049","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The European Neuroendocrine Tumour Society registry, a tool to assess the prognosis of neuroendocrine neoplasms","name":"articletitle","label":"Article Title"},{"value":"European Journal of Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejca.2022.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}