{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T17:04:52Z","timestamp":1789837492050,"version":"4.0.1"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,20]],"date-time":"2023-09-20T00:00:00Z","timestamp":1695168000000},"content-version":"vor","delay-in-days":81,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004588","name":"Istituto Pasteur-Fondazione Cenci Bolognetti","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004588","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007076","name":"Fondazione Italiana per la Ricerca sul Cancro","doi-asserted-by":"publisher","award":["24107"],"award-info":[{"award-number":["24107"]}],"id":[{"id":"10.13039\/501100007076","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003407","name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004710","name":"Fondazione Umberto Veronesi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004271","name":"Sapienza Universit\u00e0 di Roma","doi-asserted-by":"publisher","award":["RM1221814D9EBE08"],"award-info":[{"award-number":["RM1221814D9EBE08"]}],"id":[{"id":"10.13039\/501100004271","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004271","name":"Sapienza Universit\u00e0 di Roma","doi-asserted-by":"publisher","award":["RM12117A613EA3FC"],"award-info":[{"award-number":["RM12117A613EA3FC"]}],"id":[{"id":"10.13039\/501100004271","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004271","name":"Sapienza Universit\u00e0 di Roma","doi-asserted-by":"publisher","award":["RM120172B7A66A2D"],"award-info":[{"award-number":["RM120172B7A66A2D"]}],"id":[{"id":"10.13039\/501100004271","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005010","name":"Associazione Italiana per la Ricerca sul Cancro","doi-asserted-by":"publisher","award":["IG 2019"],"award-info":[{"award-number":["IG 2019"]}],"id":[{"id":"10.13039\/501100005010","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005010","name":"Associazione Italiana per la Ricerca sul Cancro","doi-asserted-by":"publisher","award":["IG-21389"],"award-info":[{"award-number":["IG-21389"]}],"id":[{"id":"10.13039\/501100005010","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005010","name":"Associazione Italiana per la Ricerca sul Cancro","doi-asserted-by":"publisher","award":["IG-24329"],"award-info":[{"award-number":["IG-24329"]}],"id":[{"id":"10.13039\/501100005010","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005010","name":"Associazione Italiana per la Ricerca sul Cancro","doi-asserted-by":"publisher","award":["IG-21614"],"award-info":[{"award-number":["IG-21614"]}],"id":[{"id":"10.13039\/501100005010","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejcancer.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Cancer"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.ejca.2023.04.022","type":"journal-article","created":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T16:41:22Z","timestamp":1683045682000},"page":"183-191","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Male breast cancer risk associated with pathogenic variants in genes other than BRCA1\/2: an Italian case-control study"],"prefix":"10.1016","volume":"188","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3475-1067","authenticated-orcid":false,"given":"Agostino","family":"Bucalo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Conti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3393-7185","authenticated-orcid":false,"given":"Virginia","family":"Valentini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Capalbo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1556-4998","authenticated-orcid":false,"given":"Alessandro","family":"Bruselles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7736-9672","authenticated-orcid":false,"given":"Marco","family":"Tartaglia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3589-2128","authenticated-orcid":false,"given":"Bernardo","family":"Bonanni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele","family":"Calistri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Coppa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8950-8561","authenticated-orcid":false,"given":"Laura","family":"Cortesi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0299-4056","authenticated-orcid":false,"given":"Giuseppe","family":"Giannini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viviana","family":"Gismondi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6034-7562","authenticated-orcid":false,"given":"Siranoush","family":"Manoukian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livia","family":"Manzella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Montagna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6951-6855","authenticated-orcid":false,"given":"Paolo","family":"Peterlongo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6298-4111","authenticated-orcid":false,"given":"Paolo","family":"Radice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Russo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Grazia","family":"Tibiletti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Turchetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Viel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines","family":"Zanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Palli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0712-9379","authenticated-orcid":false,"given":"Valentina","family":"Silvestri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8030-0449","authenticated-orcid":false,"given":"Laura","family":"Ottini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.ejca.2023.04.022_bib1","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/his.12862","article-title":"The cancer genetics and pathology of male breast cancer","volume":"68","author":"Deb","year":"2016","journal-title":"Histopathology"},{"issue":"14","key":"10.1016\/j.ejca.2023.04.022_bib2","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1200\/JCO.21.02112","article-title":"Cancer risks associated with BRCA1 and BRCA2 pathogenic variants","volume":"40","author":"Li","year":"2022","journal-title":"J Clin Oncol"},{"issue":"23","key":"10.1016\/j.ejca.2023.04.022_bib3","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1001\/jama.2017.7112","article-title":"Risks of breast, ovarian, and contralateral breast cancer for BRCA1 and BRCA2 mutation carriers","volume":"317","author":"Kuchenbaecker","year":"2017","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.ejca.2023.04.022_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ht9010001","article-title":"Applications of next generation sequencing to the analysis of familial breast\/ovarian cancer","volume":"9","author":"Zelli","year":"2020","journal-title":"High Throughput"},{"issue":"1","key":"10.1016\/j.ejca.2023.04.022_bib5","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1002\/cam4.1251","article-title":"Optimizing the identification of risk-relevant mutations by multigene panel testing in selected hereditary breast\/ovarian cancer families","volume":"7","author":"Coppa","year":"2018","journal-title":"Cancer Med"},{"issue":"10","key":"10.1016\/j.ejca.2023.04.022_bib6","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1002\/cncr.30498","article-title":"A study of over 35,000 women with breast cancer tested with a 25-gene panel of hereditary cancer genes","volume":"123","author":"Buys","year":"2017","journal-title":"Cancer"},{"issue":"9","key":"10.1016\/j.ejca.2023.04.022_bib7","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1001\/jamaoncol.2017.0424","article-title":"Associations between cancer predisposition testing panel genes and breast cancer","volume":"3","author":"Couch","year":"2017","journal-title":"JAMA Oncol"},{"issue":"5","key":"10.1016\/j.ejca.2023.04.022_bib8","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1056\/NEJMoa2005936","article-title":"A population-based study of genes previously implicated in breast cancer","volume":"384","author":"Hu","year":"2021","journal-title":"N Engl J Med"},{"issue":"5","key":"10.1016\/j.ejca.2023.04.022_bib9","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1056\/NEJMoa1913948","article-title":"Breast cancer risk genes - association analysis in more than 113,000 women","volume":"384","author":"Dorling","year":"2021","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejca.2023.04.022_bib10","unstructured":"National Comprehensive Cancer Network (NCCN). NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines\u00ae). Genetic\/Familial High-Risk Assessment: Breast, Ovarian and Pancreatic. Version 1.2023."},{"key":"10.1016\/j.ejca.2023.04.022_bib11","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1002\/ijc.32106","article-title":"Insight into genetic susceptibility to male breast cancer by multigene panel testing: results from a multicenter study in Italy","volume":"145","author":"Rizzolo","year":"2019","journal-title":"Int J Cancer"},{"issue":"13","key":"10.1016\/j.ejca.2023.04.022_bib12","doi-asserted-by":"crossref","first-page":"3292","DOI":"10.3390\/cancers14133292","article-title":"Prevalence of cancer predisposition germline variants in male breast cancer patients: results of the german consortium for hereditary breast and ovarian cancer","volume":"14","author":"Rolfes","year":"2022","journal-title":"Cancers"},{"issue":"5","key":"10.1016\/j.ejca.2023.04.022_bib13","doi-asserted-by":"crossref","first-page":"269","DOI":"10.3390\/diagnostics10050269","article-title":"Male breast cancer: results of the application of multigene panel testing to an Italian cohort of patients","volume":"10","author":"Tedaldi","year":"2020","journal-title":"Diagnostics"},{"issue":"3","key":"10.1016\/j.ejca.2023.04.022_bib14","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/s10549-019-05429-z","article-title":"Germline investigation in male breast cancer of DNA repair genes by next-generation sequencing","volume":"178","author":"Scarpitta","year":"2019","journal-title":"Breast Cancer Res Treat"},{"issue":"1","key":"10.1016\/j.ejca.2023.04.022_bib15","doi-asserted-by":"crossref","first-page":"e74","DOI":"10.1016\/j.clbc.2020.07.014","article-title":"Male breast cancer risk assessment and screening recommendations in high-risk men who undergo genetic counseling and multigene panel testing","volume":"21","author":"Gaddam","year":"2021","journal-title":"Clin Breast Cancer"},{"issue":"3","key":"10.1016\/j.ejca.2023.04.022_bib16","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1007\/s10549-016-4085-4","article-title":"Male breast cancer in a multi-gene panel testing cohort: insights and unexpected results","volume":"161","author":"Pritzlaff","year":"2017","journal-title":"Breast Cancer Res Treat"},{"issue":"1","key":"10.1016\/j.ejca.2023.04.022_bib17","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s10549-018-4661-x","article-title":"Germline deleterious mutations in genes other than BRCA2 are infrequent in male breast cancer","volume":"169","author":"Fostira","year":"2018","journal-title":"Breast Cancer Res Treat"},{"issue":"2","key":"10.1016\/j.ejca.2023.04.022_bib18","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1002\/cncr.30337","article-title":"Whole-exome sequencing and targeted gene sequencing provide insights into the role of PALB2 as a male breast cancer susceptibility gene","volume":"123","author":"Silvestri","year":"2017","journal-title":"Cancer"},{"key":"10.1016\/j.ejca.2023.04.022_bib19","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.breast.2017.12.013","article-title":"A possible role of FANCM mutations in male breast cancer susceptibility: results from a multicenter study in Italy","volume":"38","author":"Silvestri","year":"2018","journal-title":"Breast"},{"issue":"8","key":"10.1016\/j.ejca.2023.04.022_bib20","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1530\/EC-19-0225","article-title":"Evaluation of CYP17A1 and CYP1B1 polymorphisms in male breast cancer risk","volume":"8","author":"Rizzolo","year":"2019","journal-title":"Endocr Connect"},{"key":"10.1016\/j.ejca.2023.04.022_bib21","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1186\/1471-2407-7-170","article-title":"Association between the BRCA2 N372H variant and male breast cancer risk: a population-based case-control study in Tuscany, Central Italy","volume":"7","author":"Palli","year":"2007","journal-title":"BMC Cancer"},{"issue":"3","key":"10.1016\/j.ejca.2023.04.022_bib22","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.ajhg.2021.01.015","article-title":"SPEN haploinsufficiency causes a neurodevelopmental disorder overlapping proximal 1p36 deletion syndrome with an episignature of X chromosomes in females","volume":"108","author":"Radio","year":"2021","journal-title":"Am J Hum Genet"},{"issue":"7905","key":"10.1016\/j.ejca.2023.04.022_bib23","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1038\/s41586-022-04558-8","article-title":"A joint NCBI and EMBL-EBI transcript set for clinical genomics and research","volume":"604","author":"Morales","year":"2022","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.ejca.2023.04.022_bib24","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/gim.2015.30","article-title":"Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology","volume":"17","author":"Richards","year":"2015","journal-title":"Genet Med"},{"key":"10.1016\/j.ejca.2023.04.022_bib25","first-page":"877","article-title":"REVEL: an ensemble method for predicting the pathogenicity of rare missense variants","volume":"99","author":"Ioannidis","year":"2016"},{"issue":"12","key":"10.1016\/j.ejca.2023.04.022_bib26","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.1007\/s00432-018-2763-9","article-title":"Multigene panel testing beyond BRCA1\/2 in breast\/ovarian cancer Spanish families and clinical actionability of findings","volume":"144","author":"Bonache","year":"2018","journal-title":"J Cancer Res Clin Oncol"},{"key":"10.1016\/j.ejca.2023.04.022_bib27","doi-asserted-by":"crossref","first-page":"583","DOI":"10.3389\/fonc.2018.00583","article-title":"Contribution of MUTYH variants to male breast cancer risk: results from a multicenter study in Italy","volume":"8","author":"Rizzolo","year":"2018","journal-title":"Front Oncol"},{"issue":"1","key":"10.1016\/j.ejca.2023.04.022_bib28","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1002\/cncr.29010","article-title":"Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next-generation sequencing with a 25-gene panel","volume":"121","author":"Tung","year":"2015","journal-title":"Cancer"},{"issue":"8","key":"10.1016\/j.ejca.2023.04.022_bib29","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1038\/gim.2015.166","article-title":"Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing","volume":"18","author":"Susswein","year":"2016","journal-title":"Genet Med"},{"issue":"1","key":"10.1016\/j.ejca.2023.04.022_bib30","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1186\/s12885-021-08718-3","article-title":"Genetic predisposition to male breast cancer in Poland","volume":"21","author":"Szwiec","year":"2021","journal-title":"BMC Cancer"},{"issue":"1","key":"10.1016\/j.ejca.2023.04.022_bib31","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s10549-010-0797-z","article-title":"PALB2 mutations in male breast cancer: a population-based study in Central Italy","volume":"122","author":"Silvestri","year":"2010","journal-title":"Breast Cancer Res Treat"},{"issue":"1","key":"10.1016\/j.ejca.2023.04.022_bib32","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s10549-020-05922-w","article-title":"Family history of breast cancer in men with non-BRCA male breast cancer: implications for cancer risk counseling","volume":"185","author":"Calip","year":"2021","journal-title":"Breast Cancer Res Treat"},{"issue":"5","key":"10.1016\/j.ejca.2023.04.022_bib33","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2018.2140","article-title":"Exome sequencing-based screening for BRCA1\/2 expected pathogenic variants among adult biobank participants","volume":"1","author":"Manickam","year":"2018","journal-title":"JAMA Netw Open"},{"issue":"7","key":"10.1016\/j.ejca.2023.04.022_bib34","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1200\/JCO.19.01907","article-title":"Cancer risks associated with germline PALB2 pathogenic variants: an international study of 524 families","volume":"38","author":"Yang","year":"2020","journal-title":"J Clin Oncol"},{"issue":"4","key":"10.1016\/j.ejca.2023.04.022_bib35","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1158\/1940-6207.CAPR-20-0448","article-title":"Germline pathogenic variants in the ataxia telangiectasia mutated (ATM) gene are associated with high and moderate risks for multiple cancers","volume":"14","author":"Hall","year":"2021","journal-title":"Cancer Prev Res"},{"issue":"1","key":"10.1016\/j.ejca.2023.04.022_bib36","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s10549-007-9689-2","article-title":"BRCA1\/BRCA2 rearrangements and CHEK2 common mutations are infrequent in Italian male breast cancer cases","volume":"110","author":"Falchetti","year":"2008","journal-title":"Breast Cancer Res Treat"},{"issue":"1","key":"10.1016\/j.ejca.2023.04.022_bib37","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/ng879","article-title":"Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations","volume":"31","author":"Meijers-Heijboer","year":"2002","journal-title":"Nat Genet"},{"issue":"1","key":"10.1016\/j.ejca.2023.04.022_bib38","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1002\/humu.20051","article-title":"The CHEK2c.1100delC mutation plays an irrelevant role in breast cancer predisposition in Italy","volume":"24","author":"Caligo","year":"2004","journal-title":"Hum Mutat"},{"issue":"2","key":"10.1016\/j.ejca.2023.04.022_bib39","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s10549-008-0162-7","article-title":"CHEK2 1100delC and male breast cancer in the Netherlands","volume":"116","author":"Wasielewski","year":"2009","journal-title":"Breast Cancer Res Treat"},{"issue":"1","key":"10.1016\/j.ejca.2023.04.022_bib40","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1186\/s12885-017-3631-8","article-title":"CHEK2c.1100delC mutation is associated with an increased risk for male breast cancer in Finnish patient population","volume":"17","author":"Hallamies","year":"2017","journal-title":"BMC Cancer"},{"issue":"6","key":"10.1016\/j.ejca.2023.04.022_bib41","doi-asserted-by":"crossref","first-page":"3383","DOI":"10.1245\/s10434-020-09158-2","article-title":"Clinicopathological features and outcomes in individuals with breast cancer and ATM, CHEK2, or PALB2 mutations","volume":"28","author":"Bergstrom","year":"2021","journal-title":"Ann Surg Oncol"},{"issue":"6","key":"10.1016\/j.ejca.2023.04.022_bib42","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/S1470-2045(15)70142-7","article-title":"Clinical outcomes in women with breast cancer and a PALB2 mutation: a prospective cohort analysis","volume":"16","author":"Cybulski","year":"2015","journal-title":"Lancet Oncol"},{"issue":"1","key":"10.1016\/j.ejca.2023.04.022_bib43","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s13073-022-01052-8","article-title":"Breast cancer risks associated with missense variants in breast cancer susceptibility genes","volume":"14","author":"Dorling","year":"2022","journal-title":"Genome Med"},{"issue":"1","key":"10.1016\/j.ejca.2023.04.022_bib44","doi-asserted-by":"crossref","first-page":"12752","DOI":"10.1038\/s41598-019-49224-8","article-title":"REVEL and BayesDel outperform other in silico meta-predictors for clinical variant classification","volume":"9","author":"Tian","year":"2019","journal-title":"Sci Rep"}],"container-title":["European Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804923002228?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804923002228?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T06:53:09Z","timestamp":1778568789000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959804923002228"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":44,"alternative-id":["S0959804923002228"],"URL":"https:\/\/doi.org\/10.1016\/j.ejca.2023.04.022","relation":{},"ISSN":["0959-8049"],"issn-type":[{"value":"0959-8049","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Male breast cancer risk associated with pathogenic variants in genes other than BRCA1\/2: an Italian case-control study","name":"articletitle","label":"Article Title"},{"value":"European Journal of Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejca.2023.04.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}