{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T20:59:11Z","timestamp":1790283551760,"version":"4.1.0"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejcancer.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Cancer"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.ejca.2023.113244","type":"journal-article","created":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T11:55:26Z","timestamp":1689681326000},"page":"113244","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Trends and variation in treatment of early breast cancer in European certified breast centres: an EUSOMA-based\u00a0analysis"],"prefix":"10.1016","volume":"192","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7356-8877","authenticated-orcid":false,"given":"Lien","family":"van Walle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Verhoeven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenza","family":"Marotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Ponti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariano","family":"Tomatis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel T.","family":"Rubio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10125","key":"10.1016\/j.ejca.2023.113244_bib1","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S0140-6736(17)33326-3","article-title":"Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries","volume":"391","author":"Allemani","year":"2018","journal-title":"Lancet"},{"issue":"9","key":"10.1016\/j.ejca.2023.113244_bib2","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1016\/j.ejca.2010.02.016","article-title":"Variation in 'standard care' for breast cancer across Europe: a EUROCARE-3 high resolution study","volume":"46","author":"Allemani","year":"2010","journal-title":"Eur J Cancer"},{"issue":"10","key":"10.1016\/j.ejca.2023.113244_bib3","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1093\/annonc\/mdz189","article-title":"Early breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up","volume":"30","author":"Cardoso","year":"2019","journal-title":"Ann Oncol"},{"issue":"10","key":"10.1016\/j.ejca.2023.113244_bib4","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1016\/j.ejso.2015.06.006","article-title":"The effect of EUSOMA certification on quality of breast cancer care","volume":"41","author":"Van Dam","year":"2015","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.ejca.2023.113244_bib5","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.breast.2019.03.002","article-title":"Trends in axillary lymph node dissection for early-stage breast cancer in Europe: impact of evidence on practice","volume":"45","author":"Garcia-Etienne","year":"2019","journal-title":"Breast"},{"issue":"10","key":"10.1016\/j.ejca.2023.113244_bib6","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1016\/j.ejca.2015.03.013","article-title":"Variations in compliance to quality indicators by age for 41,871 breast cancer patients across Europe: a European Society of Breast Cancer Specialists database analysis","volume":"51","author":"Kiderlen","year":"2015","journal-title":"Eur J Cancer"},{"issue":"4","key":"10.1016\/j.ejca.2023.113244_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.esmoop.2021.100207","article-title":"Assessment of potential process quality indicators for systemic treatment of breast cancer in Belgium: a population-based study","volume":"6","author":"van Walle","year":"2021","journal-title":"ESMO Open"},{"key":"10.1016\/j.ejca.2023.113244_bib8","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1186\/1471-2407-14-596","article-title":"Regional variation in breast cancer treatment in the Netherlands and the role of external peer review: a cohort study comprising 63,516 women","volume":"14","author":"Kilsdonk","year":"2014","journal-title":"BMC Cancer"},{"issue":"2","key":"10.1016\/j.ejca.2023.113244_bib9","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.breast.2014.11.014","article-title":"Quality of care in breast cancer centers: results of benchmarking by the German Cancer Society and German Society for Breast Diseases","volume":"24","author":"Kowalski","year":"2015","journal-title":"Breast"},{"issue":"7","key":"10.1016\/j.ejca.2023.113244_bib10","doi-asserted-by":"crossref","first-page":"e327","DOI":"10.1016\/S1470-2045(20)30741-5","article-title":"Updated recommendations regarding the management of older patients with breast cancer: a joint paper from the European Society of Breast Cancer Specialists (EUSOMA) and the International Society of Geriatric Oncology (SIOG)","volume":"22","author":"Biganzoli","year":"2021","journal-title":"Lancet Oncol"},{"issue":"1","key":"10.1016\/j.ejca.2023.113244_bib11","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/s41416-018-0090-1","article-title":"Variation in treatment and survival of older patients with non-metastatic breast cancer in five European countries: a population-based cohort study from the EURECCA Breast Cancer Group","volume":"119","author":"Derks","year":"2018","journal-title":"Br J Cancer"},{"key":"10.1016\/j.ejca.2023.113244_bib12","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1016\/S0140-6736(14)60488-8","article-title":"Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials","volume":"383","author":"McGale","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.ejca.2023.113244_bib13","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1056\/NEJMoa1415369","article-title":"Internal mammary and medial supraclavicular irradiation in breast cancer","volume":"373","author":"Poortmans","year":"2015","journal-title":"N Engl J Med"},{"issue":"7","key":"10.1016\/j.ejca.2023.113244_bib14","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1002\/1878-0261.12690","article-title":"Provision and use of radiotherapy in Europe","volume":"14","author":"Lievens","year":"2020","journal-title":"Mol Oncol"},{"issue":"1","key":"10.1016\/j.ejca.2023.113244_bib15","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/s13014-022-02043-0","article-title":"Transparency in quality of radiotherapy for breast cancer in the Netherlands: a national registration of radiotherapy-parameters","volume":"17","author":"Maliko","year":"2022","journal-title":"Radiat Oncol"},{"issue":"1","key":"10.1016\/j.ejca.2023.113244_bib16","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S1470-2045(10)70266-7","article-title":"Effect of tamoxifen and radiotherapy in women with locally excised ductal carcinoma in situ: long-term results from the UK\/ANZ DCIS trial","volume":"12","author":"Cuzick","year":"2011","journal-title":"Lancet Oncol"},{"issue":"10","key":"10.1016\/j.ejca.2023.113244_bib17","doi-asserted-by":"crossref","first-page":"e442","DOI":"10.1016\/S1470-2045(16)30367-9","article-title":"Treatment of low-risk ductal carcinoma in situ: is nothing better than something?","volume":"17","author":"Benson","year":"2016","journal-title":"Lancet Oncol"},{"issue":"15","key":"10.1016\/j.ejca.2023.113244_bib18","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.1016\/j.ejca.2014.07.019","article-title":"International variation in management of screen-detected ductal carcinoma in situ of the breast","volume":"50","author":"Ponti","year":"2014","journal-title":"Eur J Cancer"},{"issue":"10","key":"10.1016\/j.ejca.2023.113244_bib19","doi-asserted-by":"crossref","first-page":"3264","DOI":"10.1245\/s10434-015-4668-z","article-title":"Adjuvant endocrine therapy in patients with ductal carcinoma in situ: a population-based retrospective analysis from 2005 to 2012 in the National Cancer Data Base","volume":"22","author":"Flanagan","year":"2015","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.ejca.2023.113244_bib20","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.ejca.2017.08.017","article-title":"Quality indicators in breast cancer care: an update from the EUSOMA working group","volume":"86","author":"Biganzoli","year":"2017","journal-title":"Eur J Cancer"},{"issue":"3","key":"10.1016\/j.ejca.2023.113244_bib21","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/S1470-2045(14)71221-5","article-title":"PRIME II investigators. Breast-conserving surgery with or without irradiation in women aged 65 years or older with early breast cancer (PRIME II): a randomised controlled trial","volume":"16","author":"Kunkler","year":"2015","journal-title":"Lancet Oncol"},{"issue":"14","key":"10.1016\/j.ejca.2023.113244_bib22","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1056\/NEJM199710023371401","article-title":"Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy. Danish Breast Cancer Cooperative Group 82b Trial","volume":"337","author":"Overgaard","year":"1997","journal-title":"N Engl J Med"},{"issue":"36","key":"10.1016\/j.ejca.2023.113244_bib23","doi-asserted-by":"crossref","first-page":"4431","DOI":"10.1200\/JCO.2016.69.1188","article-title":"Postmastectomy radiotherapy: an American Society of Clinical Oncology, American Society for Radiation Oncology, and Society of Surgical Oncology focused guideline update","volume":"34","author":"Recht","year":"2016","journal-title":"J Clin Oncol"},{"issue":"6","key":"10.1016\/j.ejca.2023.113244_bib24","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1093\/annonc\/mdv162","article-title":"Determining the indications for post mastectomy radiotherapy: moving from 20th century clinical staging to 21st century biological criteria","volume":"26","author":"Russell","year":"2015","journal-title":"Ann Oncol"},{"issue":"3","key":"10.1016\/j.ejca.2023.113244_bib25","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1093\/annonc\/mdu561","article-title":"Patterns of practice of regional nodal irradiation in breast cancer: results of the European Organization for Research and Treatment of Cancer (EORTC) NOdal Radiotherapy (NORA) survey","volume":"26","author":"Belkacemi","year":"2015","journal-title":"Ann Oncol"},{"issue":"24","key":"10.1016\/j.ejca.2023.113244_bib26","doi-asserted-by":"crossref","first-page":"3927","DOI":"10.1200\/JCO.2006.06.9054","volume":"24","author":"Taghian","year":"2006","journal-title":"J Clin Oncol"},{"issue":"1","key":"10.1016\/j.ejca.2023.113244_bib27","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1007\/s12253-018-0553-y","article-title":"Endocrine therapy for ductal carcinoma in situ (DCIS) of the breast with breast conserving surgery (BCS) and radiotherapy (RT): a meta-analysis","volume":"26","author":"Yan","year":"2020","journal-title":"Pathol Oncol Res"},{"issue":"19","key":"10.1016\/j.ejca.2023.113244_bib28","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1200\/JCO.18.01779","article-title":"Randomized placebo controlled trial of low-dose tamoxifen to prevent local and contralateral recurrence in breast intraepithelial neoplasia","volume":"37","author":"DeCensi","year":"2019","journal-title":"J Clin Oncol"},{"issue":"21","key":"10.1016\/j.ejca.2023.113244_bib29","doi-asserted-by":"crossref","first-page":"2386","DOI":"10.1200\/JCO.21.00831","article-title":"Cost-effectiveness of adjuvant treatment for ductal carcinoma in situ","volume":"39","author":"Gupta","year":"2021","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ejca.2023.113244_bib30","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1038\/bjc.2011.105","article-title":"Long-term clinical outcome of oestrogen receptor-positive operable primary breast cancer in older women: a large series from a single centre","volume":"104","author":"Syed","year":"2011","journal-title":"Br J Cancer"},{"issue":"7","key":"10.1016\/j.ejca.2023.113244_bib31","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1038\/sj.bjc.6603600","article-title":"Surgery, with or without tamoxifen, vs tamoxifen alone for older women with operable breast cancer: cochrane review","volume":"96","author":"Hind","year":"2007","journal-title":"Br J Cancer"},{"key":"10.1016\/j.ejca.2023.113244_bib32","doi-asserted-by":"crossref","first-page":"153","DOI":"10.25122\/jml-2021-0108","article-title":"Triple-negative breast cancer: current treatment strategies and factors of negative prognosis","volume":"15","author":"Baranova","year":"2022","journal-title":"J Med Life"},{"issue":"1","key":"10.1016\/j.ejca.2023.113244_bib33","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/s41523-022-00468-0","article-title":"Triple negative breast cancer: pitfalls and progress","volume":"8","author":"Zagami","year":"2022","journal-title":"NPJ Breast Cancer"},{"issue":"1","key":"10.1016\/j.ejca.2023.113244_bib34","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1038\/s41598-022-05209-8","article-title":"Efficacy of adjuvant trastuzumab in women with HER2-positive T1a or bN0M0 breast cancer: a population-based cohort study","volume":"12","author":"Ali","year":"2022","journal-title":"Sci Rep"},{"key":"10.1016\/j.ejca.2023.113244_bib35","unstructured":"European Cancer Information System (ECIS). List of cancer registries.pdf (europa.eu),\u00a0[accessed on 14.06.2023], \u00a9European Union,\u00a02023."}],"container-title":["European Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804923003465?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804923003465?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T20:41:54Z","timestamp":1760733714000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959804923003465"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":35,"alternative-id":["S0959804923003465"],"URL":"https:\/\/doi.org\/10.1016\/j.ejca.2023.113244","relation":{},"ISSN":["0959-8049"],"issn-type":[{"value":"0959-8049","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Trends and variation in treatment of early breast cancer in European certified breast centres: an EUSOMA-based\u00a0analysis","name":"articletitle","label":"Article Title"},{"value":"European Journal of Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejca.2023.113244","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"113244"}}