{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:01:29Z","timestamp":1762300889481,"version":"build-2065373602"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejcancer.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Cancer"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.ejca.2025.115387","type":"journal-article","created":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T03:57:04Z","timestamp":1743134224000},"page":"115387","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Association between premature menopause and the risk of biliary tract cancer: A nationwide cohort study"],"prefix":"10.1016","volume":"220","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4450-3350","authenticated-orcid":false,"given":"Chi Hoon","family":"Maeng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyungdo","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1363-9332","authenticated-orcid":false,"given":"Jung Yong","family":"Hong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4358-4208","authenticated-orcid":false,"given":"Joo-Hyun","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.ejca.2025.115387_bib1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/nrclinonc.2017.157","article-title":"Cholangiocarcinoma \u2014 evolving concepts and therapeutic strategies","volume":"15","author":"Rizvi","year":"2018","journal-title":"Nat Rev Clin Oncol"},{"issue":"9935","key":"10.1016\/j.ejca.2025.115387_bib2","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.1016\/S0140-6736(13)61903-0","article-title":"Cholangiocarcinoma","volume":"383","author":"Razumilava","year":"2014","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.ejca.2025.115387_bib3","first-page":"7","article-title":"Cancer statistics, 2022","volume":"72","author":"Siegel","year":"2022","journal-title":"CA: Cancer J Clin"},{"issue":"1","key":"10.1016\/j.ejca.2025.115387_bib4","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1186\/s12876-022-02637-8","article-title":"The epidemiological trends of biliary tract cancers in the United States of America","volume":"22","author":"Jiang","year":"2022","journal-title":"BMC Gastroenterol"},{"issue":"5","key":"10.1016\/j.ejca.2025.115387_bib5","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1172\/JCI110369","article-title":"Biliary lipids, bile acids, and gallbladder function in the human female. Effects of pregnancy and the ovulatory cycle","volume":"68","author":"Kern","year":"1981","journal-title":"J Clin Investig"},{"issue":"4","key":"10.1016\/j.ejca.2025.115387_bib6","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/0016-5085(82)90316-X","article-title":"Gallbladder function in the human female: effect of the ovulatory cycle, pregnancy, and contraceptive steroids","volume":"82","author":"Everson","year":"1982","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.ejca.2025.115387_bib7","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.dld.2011.06.014","article-title":"An oestrogen receptor \u03b2-selective agonist exerts anti-neoplastic effects in experimental intrahepatic cholangiocarcinoma","volume":"44","author":"Marzioni","year":"2012","journal-title":"Dig Liver Dis"},{"issue":"3","key":"10.1016\/j.ejca.2025.115387_bib8","doi-asserted-by":"crossref","first-page":"877","DOI":"10.2353\/ajpath.2006.050464","article-title":"Estrogens and Insulin-Like Growth Factor 1 Modulate Neoplastic Cell Growth in Human Cholangiocarcinoma","volume":"169","author":"Alvaro","year":"2006","journal-title":"Am J Pathol"},{"issue":"22","key":"10.1016\/j.ejca.2025.115387_bib9","doi-asserted-by":"crossref","first-page":"3537","DOI":"10.3748\/wjg.v12.i22.3537","article-title":"Estrogens and the pathophysiology of the biliary tree","volume":"12","author":"Alvaro","year":"2006","journal-title":"World J Gastroenterol: WJG"},{"issue":"2","key":"10.1016\/j.ejca.2025.115387_bib10","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/hep.32254","article-title":"Menopausal hormone therapy and risk of biliary tract cancers: addressing the ant, not the elephant in the room","volume":"75","author":"Rubino","year":"2022","journal-title":"Hepatology"},{"issue":"4","key":"10.1016\/j.ejca.2025.115387_bib11","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.jhep.2020.04.046","article-title":"Associations between reproductive factors and biliary tract cancers in women from the Biliary Tract Cancers Pooling Project","volume":"73","author":"Jackson","year":"2020","journal-title":"J Hepatol"},{"issue":"7","key":"10.1016\/j.ejca.2025.115387_bib12","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1038\/sj.bjc.6605597","article-title":"Reproductive factors and risks of biliary tract cancers and stones: a population-based study in Shanghai, China","volume":"102","author":"Andreotti","year":"2010","journal-title":"Br J Cancer"},{"issue":"3","key":"10.1016\/j.ejca.2025.115387_bib13","doi-asserted-by":"crossref","first-page":"370","DOI":"10.3109\/0284186X.2015.1063775","article-title":"Incidence of cancer among grand multiparous women in Finland with special focus on non-gynaecological cancers: a population-based cohort study","volume":"55","author":"H\u00f6gn\u00e4s","year":"2016","journal-title":"Acta Oncol"},{"issue":"8","key":"10.1016\/j.ejca.2025.115387_bib14","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.3109\/0284186X.2015.1016627","article-title":"Reproductive factors and risk of biliary tract cancer in a population-based study","volume":"54","author":"Kilander","year":"2015","journal-title":"Acta Oncol (Stockh, Swed)"},{"issue":"6","key":"10.1016\/j.ejca.2025.115387_bib15","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1002\/ijc.2910540613","article-title":"Parity and cancers of the gall bladder and the extrahepatic bile ducts","volume":"54","author":"Lambe","year":"1993","journal-title":"Int J Cancer"},{"issue":"2","key":"10.1016\/j.ejca.2025.115387_bib16","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/ijc.2910570203","article-title":"Reproductive history and cancer of the biliary tract in women","volume":"57","author":"Moerman","year":"1994","journal-title":"Int J Cancer"},{"issue":"4","key":"10.1016\/j.ejca.2025.115387_bib17","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1097\/00008469-200308000-00005","article-title":"Lifestyle, parity, menstrual and reproductive factors and risk of gallbladder cancer","volume":"12","author":"Pandey","year":"2003","journal-title":"Eur J Cancer Prev"},{"issue":"4","key":"10.1016\/j.ejca.2025.115387_bib18","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1097\/00008469-199608000-00004","article-title":"Menstrual and reproductive factors and biliary tract cancers","volume":"5","author":"Tavani","year":"1996","journal-title":"Eur J Cancer Prev"},{"issue":"3","key":"10.1016\/j.ejca.2025.115387_bib19","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1093\/ije\/dyab197","article-title":"Reproductive factors and gall-bladder cancer, and the effect of common genetic variants on these associations: a case-control study in India","volume":"51","author":"Mhatre","year":"2022","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.ejca.2025.115387_bib20","article-title":"Management of perimenopausal and menopausal symptoms","volume":"382","author":"Duralde","year":"2023","journal-title":"BMJ (Clin Res Ed)"},{"issue":"4","key":"10.1016\/j.ejca.2025.115387_bib21","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1097\/CEJ.0000000000000260","article-title":"Reproductive factors and gallbladder\/bile duct cancer: a population-based cohort study in Japan","volume":"26","author":"Makiuchi","year":"2017","journal-title":"Eur J Cancer Prev"},{"key":"10.1016\/j.ejca.2025.115387_bib22","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/290575","article-title":"Progesterone and related compounds in hepatocellular carcinoma: basic and clinical aspects","volume":"2013","author":"Yeh","year":"2013","journal-title":"BioMed Res Int"},{"issue":". 1","key":"10.1016\/j.ejca.2025.115387_bib23","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1159\/000315247","article-title":"Gender disparity of hepatocellular carcinoma: the roles of sex hormones","volume":"78","author":"Yeh","year":"2010","journal-title":"Oncology"}],"container-title":["European Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804925001686?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959804925001686?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T18:48:15Z","timestamp":1760640495000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959804925001686"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":23,"alternative-id":["S0959804925001686"],"URL":"https:\/\/doi.org\/10.1016\/j.ejca.2025.115387","relation":{},"ISSN":["0959-8049"],"issn-type":[{"type":"print","value":"0959-8049"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between premature menopause and the risk of biliary tract cancer: A nationwide cohort study","name":"articletitle","label":"Article Title"},{"value":"European Journal of Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejca.2025.115387","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"115387"}}