{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:29:28Z","timestamp":1790702968074,"version":"4.1.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]},{"name":"SPP1150"},{"name":"SPP1464"},{"name":"Bavarian Genome Research Network"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Cell Biology"],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.1016\/j.ejcb.2010.10.011","type":"journal-article","created":{"date-parts":[[2010,12,4]],"date-time":"2010-12-04T04:21:02Z","timestamp":1291436462000},"page":"922-925","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Actin dynamics at intracellular membranes: The Spir\/formin nucleator complex"],"prefix":"10.1016","volume":"90","author":[{"given":"Eugen","family":"Kerkhoff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejcb.2010.10.011_bib0005","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.ceb.2008.12.001","article-title":"Actin nucleation and elongation factors: mechanisms and interplay","volume":"21","author":"Chesarone","year":"2009","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.ejcb.2010.10.011_bib0010","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.devcel.2007.09.003","article-title":"Capu and Spire assemble a cytoplasmic actin mesh that maintains microtubule organization in the Drosophila oocyte","volume":"13","author":"Dahlgaard","year":"2007","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ejcb.2010.10.011_bib0015","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.tibs.2005.04.014","article-title":"Formin proteins: a domain-based approach","volume":"30","author":"Higgs","year":"2005","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.ejcb.2010.10.011_bib0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1091\/mbc.e04-07-0565","article-title":"Phylogenetic analysis of the formin homology 2 domain","volume":"16","author":"Higgs","year":"2005","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.ejcb.2010.10.011_bib0025","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.tcb.2006.07.005","article-title":"Cellular functions of the Spir actin-nucleation factors","volume":"16","author":"Kerkhoff","year":"2006","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.ejcb.2010.10.011_bib0030","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1016\/S0960-9822(01)00602-9","article-title":"The Spir actin organizers are involved in vesicle transport processes","volume":"11","author":"Kerkhoff","year":"2001","journal-title":"Curr. Biol."},{"key":"10.1016\/j.ejcb.2010.10.011_bib0035","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/ncb1075","article-title":"Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables","volume":"6","author":"Kobielak","year":"2004","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ejcb.2010.10.011_bib0040","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ceb.2005.12.011","article-title":"Molecular details of formin-mediated actin assembly","volume":"18","author":"Kovar","year":"2006","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.ejcb.2010.10.011_bib0045","doi-asserted-by":"crossref","first-page":"4176","DOI":"10.1038\/sj.emboj.7600879","article-title":"The regulation of mDia1 by autoinhibition and its release by Rho*GTP","volume":"24","author":"Lammers","year":"2005","journal-title":"EMBO J."},{"key":"10.1016\/j.ejcb.2010.10.011_bib0050","doi-asserted-by":"crossref","first-page":"6986","DOI":"10.1074\/jbc.M411605200","article-title":"Dissecting requirements for auto-inhibition of actin nucleation by the formin, mDia1","volume":"280","author":"Li","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ejcb.2010.10.011_bib0055","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1101\/gad.3.9.1437","article-title":"Cappuccino and spire: two unique maternal-effect loci required for both the anteroposterior and dorsoventral patterns of the Drosophila embryo","volume":"3","author":"Manseau","year":"1989","journal-title":"Genes Dev."},{"key":"10.1016\/j.ejcb.2010.10.011_bib0060","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/S0092-8674(00)80776-X","article-title":"Crystal structure of a phosphatidylinositol 3-phosphate-specific membrane-targeting motif, the FYVE domain of Vps27p","volume":"97","author":"Misra","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.ejcb.2010.10.011_bib0065","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.devcel.2009.01.007","article-title":"Annexin A2-dependent polymerization of actin mediates endosome biogenesis","volume":"16","author":"Morel","year":"2009","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ejcb.2010.10.011_bib0070","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S0092-8674(00)80549-8","article-title":"Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A","volume":"96","author":"Ostermeier","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.ejcb.2010.10.011_bib0075","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.molcel.2005.04.002","article-title":"Structural basis of Rho GTPase-mediated activation of the formin mDia1","volume":"18","author":"Otomo","year":"2005","journal-title":"Mol. Cell"},{"key":"10.1016\/j.ejcb.2010.10.011_bib0080","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0960-9822(00)00388-2","article-title":"The p150-Spir protein provides a link between c-Jun N-terminal kinase function and actin reorganization","volume":"10","author":"Otto","year":"2000","journal-title":"Curr. Biol."},{"key":"10.1016\/j.ejcb.2010.10.011_bib0085","doi-asserted-by":"crossref","first-page":"25324","DOI":"10.1074\/jbc.M109.030320","article-title":"Identification of a short Spir interaction sequence at the C-terminal end of formin subgroup proteins","volume":"284","author":"Pechlivanis","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ejcb.2010.10.011_bib0090","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1146\/annurev.biophys.35.040405.101936","article-title":"Regulation of actin filament assembly by Arp2\/3 complex and formins","volume":"36","author":"Pollard","year":"2007","journal-title":"Annu. Rev. Biophys. Biomol. Struct."},{"key":"10.1016\/j.ejcb.2010.10.011_bib0095","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/ncb0108-13","article-title":"Actin nucleation: bacteria get in-Spired","volume":"10","author":"Quinlan","year":"2008","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ejcb.2010.10.011_bib0100","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/nature03241","article-title":"Drosophila Spire is an actin nucleation factor","volume":"433","author":"Quinlan","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.ejcb.2010.10.011_bib0105","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1083\/jcb.200706196","article-title":"Regulatory interactions between two actin nucleators, Spire and Cappuccino","volume":"179","author":"Quinlan","year":"2007","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ejcb.2010.10.011_bib0110","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/ncb1385","article-title":"Coordination of microtubule and microfilament dynamics by Drosophila Rho1, Spire and Cappuccino","volume":"8","author":"Rosales-Nieves","year":"2006","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ejcb.2010.10.011_bib0115","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/nature03604","article-title":"Structural and mechanistic insights into the interaction between Rho and mammalian Dia","volume":"435","author":"Rose","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.ejcb.2010.10.011_bib0120","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1083\/jcb.149.4.901","article-title":"Distinct membrane domains on endosomes in the recycling pathway visualized by multicolor imaging of Rab4, Rab5, and Rab11","volume":"149","author":"Sonnichsen","year":"2000","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ejcb.2010.10.011_bib0125","doi-asserted-by":"crossref","first-page":"5267","DOI":"10.1242\/dev.126.23.5267","article-title":"Spire contains actin binding domains and is related to ascidian posterior end mark-5","volume":"126","author":"Wellington","year":"1999","journal-title":"Development"}],"container-title":["European Journal of Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171933510002293?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171933510002293?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T17:14:22Z","timestamp":1759252462000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0171933510002293"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":25,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["S0171933510002293"],"URL":"https:\/\/doi.org\/10.1016\/j.ejcb.2010.10.011","relation":{},"ISSN":["0171-9335"],"issn-type":[{"value":"0171-9335","type":"print"}],"subject":[],"published":{"date-parts":[[2011,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Actin dynamics at intracellular membranes: The Spir\/formin nucleator complex","name":"articletitle","label":"Article Title"},{"value":"European Journal of Cell Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejcb.2010.10.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}