{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T02:11:06Z","timestamp":1790647866240,"version":"4.1.0"},"reference-count":69,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["RO2414\/3-2"],"award-info":[{"award-number":["RO2414\/3-2"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["STR666\/5-2"],"award-info":[{"award-number":["STR666\/5-2"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["FA330\/9-1"],"award-info":[{"award-number":["FA330\/9-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Cell Biology"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1016\/j.ejcb.2017.08.003","type":"journal-article","created":{"date-parts":[[2017,9,4]],"date-time":"2017-09-04T21:16:57Z","timestamp":1504559817000},"page":"715-727","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":38,"title":["Differential functions of WAVE regulatory complex subunits in the regulation of actin-driven processes"],"prefix":"10.1016","volume":"96","author":[{"given":"Christof","family":"Litschko","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joern","family":"Linkner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Br\u00fchmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresia E.B.","family":"Stradal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Reinl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lothar","family":"J\u00e4nsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klemens","family":"Rottner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Faix","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejcb.2017.08.003_bib0005","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.cell.2007.08.030","article-title":"Cordon-Bleu is an actin nucleation factor and controls neuronal morphology","volume":"131","author":"Ahuja","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0010","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1083\/jcb.142.5.1325","article-title":"SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development","volume":"142","author":"Bear","year":"1998","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0015","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/S0960-9822(03)00580-3","article-title":"PIR121 regulates pseudopod dynamics and SCAR activity in Dictyostelium","volume":"13","author":"Blagg","year":"2003","journal-title":"Curr. Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0020","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1152\/physrev.00018.2013","article-title":"Actin dynamics, architecture, and mechanics in cell motility","volume":"94","author":"Blanchoin","year":"2014","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0025","doi-asserted-by":"crossref","first-page":"2943","DOI":"10.1038\/emboj.2008.211","article-title":"Clustering of VASP actively drives processive, WH2 domain-mediated actin filament elongation","volume":"27","author":"Breitsprecher","year":"2008","journal-title":"EMBO J."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0030","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1038\/nrm2867","article-title":"A nucleator arms race: cellular control of actin assembly","volume":"11","author":"Campellone","year":"2010","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0035","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1091\/mbc.e06-06-0518","article-title":"The N-terminus of Dictyostelium Scar interacts with Abi and HSPC300 and is essential for proper regulation and function","volume":"18","author":"Caracino","year":"2007","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0040","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1038\/nature09623","article-title":"Structure and control of the actin regulatory WAVE complex","volume":"468","author":"Chen","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0045","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.devcel.2014.08.001","article-title":"Ena\/VASP proteins cooperate with the WAVE complex to regulate the actin cytoskeleton","volume":"30","author":"Chen","year":"2014","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0050","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1126\/science.1155313","article-title":"Leiomodin is an actin filament nucleator in muscle cells","volume":"320","author":"Chereau","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0055","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1038\/nrm2816","article-title":"Unleashing formins to remodel the actin and microtubule cytoskeletons","volume":"11","author":"Chesarone","year":"2010","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0060","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1038\/ncb1007-1110","article-title":"The many faces of actin: matching assembly factors with cellular structures","volume":"9","author":"Chhabra","year":"2007","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0065","doi-asserted-by":"crossref","first-page":"e27033","DOI":"10.4161\/cib.27033","article-title":"SCAR\/WAVE","volume":"6","author":"Davidson","year":"2013","journal-title":"Commun. Integr. Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0070","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.devcel.2009.09.010","article-title":"The arp2\/3 activator WASH controls the fission of endosomes through a large multiprotein complex","volume":"17","author":"Derivery","year":"2009","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0075","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1161\/ATVBAHA.109.200683","article-title":"Characterization of a novel interaction between vasodilator-stimulated phosphoprotein and Abelson interactor 1 in human platelets: a concerted computational and experimental approach","volume":"30","author":"Dittrich","year":"2010","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"Pt 12","key":"10.1016\/j.ejcb.2017.08.003_bib0080","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1242\/jcs.113.12.2253","article-title":"Rac1 GTPases control filopodia formation, cell motility, endocytosis, cytokinesis and development in Dictyostelium","volume":"113","author":"Dumontier","year":"2000","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0085","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1038\/nature00859","article-title":"Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck","volume":"418","author":"Eden","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0090","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.devcel.2006.05.001","article-title":"Staying in shape with formins","volume":"10","author":"Faix","year":"2006","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0095","doi-asserted-by":"crossref","first-page":"e143","DOI":"10.1093\/nar\/gnh136","article-title":"A rapid and efficient method to generate multiple gene disruptions in Dictyostelium discoideum using a single selectable marker and the Cre-loxP system","volume":"32","author":"Faix","year":"2004","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0100","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/978-1-62703-302-2_13","article-title":"The application of the cre-loxP system for generating multiple knock-out and knock-in targeted loci","author":"Faix","year":"2013","journal-title":"Methods Mol. Biol. (Clifton N.J.)"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0105","doi-asserted-by":"crossref","first-page":"4379","DOI":"10.1073\/pnas.0400628101","article-title":"Purification and architecture of the ubiquitous Wave complex","volume":"101","author":"Gautreau","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0110","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1038\/nrm2026","article-title":"The ARP2\/3 complex: an actin nucleator comes of age","volume":"7","author":"Goley","year":"2006","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0115","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1242\/jcs.110.2.105","article-title":"Fluid-phase uptake by macropinocytosis in Dictyostelium","author":"Hacker","year":"1997","journal-title":"J. Cell Sci"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0120","first-page":"817","article-title":"A preparation protocol for postem\u2013 bedding electron microscopy of Dictyostelium discoideum cells with monoclonal antibodies","volume":"6","author":"Humbel","year":"1992","journal-title":"Scanning Microsc."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0125","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.cub.2006.02.068","article-title":"Nap1 regulates dictyostelium cell motility and adhesion through SCAR-Dependent and \u2013independent pathways","volume":"16","author":"Ibarra","year":"2006","journal-title":"Curr. Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0130","doi-asserted-by":"crossref","first-page":"4926","DOI":"10.1038\/sj.onc.1204502","article-title":"Inhibition of v-Abl transformation in 3T3 cells overexpressing different forms of the Abelson interactor protein Abi-1","volume":"20","author":"Ikeguchi","year":"2001","journal-title":"Oncogene"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0135","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1038\/ncb1105","article-title":"Abi1 is essential for the formation and activation of a WAVE2 signalling complex","volume":"6","author":"Innocenti","year":"2004","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0140","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1038\/nsmb.1587","article-title":"The WAVE regulatory complex is inhibited","volume":"16","author":"Ismail","year":"2009","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0145","doi-asserted-by":"crossref","first-page":"E7464","DOI":"10.1073\/pnas.1611024113","article-title":"A Diaphanous \u2013related formin links Ras signaling directly to actin assembly in macropinocytosis and phagocytosis","volume":"113","author":"Junemann","year":"2016","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0150","doi-asserted-by":"crossref","first-page":"2246","DOI":"10.1242\/jcs.063735","article-title":"SCAR\/WAVE is activated at mitosis and drives myosin-independent cytokinesis","volume":"123","author":"King","year":"2010","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0155","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1074\/jbc.273.1.291","article-title":"p140Sra-1 (specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase","volume":"273","author":"Kobayashi","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0160","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.cell.2005.11.038","article-title":"Control of the assembly of ATP- and ADP-Actin by formins and profilin","volume":"124","author":"Kovar","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0165","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/nrm3861","article-title":"Steering cell migration: lamellipodium dynamics and the regulation of directional persistence","volume":"15","author":"Krause","year":"2014","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0170","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.devcel.2004.07.024","article-title":"Lamellipodin, an Ena\/VASP ligand, is implicated in the regulation of lamellipodial dynamics","volume":"7","author":"Krause","year":"2004","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0175","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1016\/j.cub.2003.10.005","article-title":"Abi, Sra1, and Kette control the stability and localization of SCAR\/WAVE to regulate the formation of actin-based protrusions","volume":"13","author":"Kunda","year":"2003","journal-title":"Curr. Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0180","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1152\/physrev.00021.2007","article-title":"Regulation of actin assembly associated with protrusion and adhesion in cell migration","volume":"88","author":"Le Clainche","year":"2008","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0185","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1038\/ncb3426","article-title":"Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes","volume":"18","author":"Leithner","year":"2016","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0190","doi-asserted-by":"crossref","first-page":"e21327","DOI":"10.1371\/journal.pone.0021327","article-title":"High-resolution x-ray structure of the trimeric scar\/WAVE-complex precursor brk1","volume":"6","author":"Linkner","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0195","article-title":"Dicty Tracking: A standalone tool for fast and easy tracking of migrating Dictyostelium cells","author":"Litschko","year":"2017","journal-title":"Figshare"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0200","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1083\/jcb.127.1.107","article-title":"Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose","volume":"127","author":"Machesky","year":"1994","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0205","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.cub.2010.03.048","article-title":"c-Abl, Lamellipodin, and Ena\/VASP proteins cooperate in dorsal ruffling of fibroblasts and axonal morphogenesis","volume":"20","author":"Michael","year":"2010","journal-title":"Curr. Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0210","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1093\/jb\/mvg146","article-title":"Regulation of actin dynamics by WASP family proteins","volume":"134","author":"Miki","year":"2003","journal-title":"J. Biochem."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0215","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1083\/jcb.136.2.331","article-title":"Structure, subunit topology, and actin-binding activity of the Arp2\/3 complex from Acanthamoeba","volume":"136","author":"Mullins","year":"1997","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0220","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0092-8674(03)00120-X","article-title":"Cellular motility driven by assembly and disassembly of actin filaments","volume":"112","author":"Pollard","year":"2003","journal-title":"Cell"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0225","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1126\/science.1175862","article-title":"Actin, a central player in cell shape and movement","volume":"326","author":"Pollard","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0230","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1146\/annurev.biophys.35.040405.101936","article-title":"Regulation of actin filament assembly by arp2\/3 complex and formins","volume":"36","author":"Pollard","year":"2007","journal-title":"Annu. Rev. Biophys. Biomol. Struct."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0235","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.cub.2008.01.026","article-title":"Abi mutants in dictyostelium reveal specific roles for the SCAR\/WAVE complex in cytokinesis","volume":"18","author":"Pollitt","year":"2008","journal-title":"Curr. Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0240","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1471-2121-10-13","article-title":"Loss of Dictyostelium HSPC300 causes a scar-like phenotype and loss of SCAR protein","volume":"10","author":"Pollitt","year":"2009","journal-title":"BMC Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0245","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1126\/science.1072309","article-title":"Role of formins in actin assembly: nucleation and barbed-end association","volume":"297","author":"Pruyne","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0250","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/nature03241","article-title":"Drosophila Spire is an actin nucleation factor","volume":"433","author":"Quinlan","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0255","doi-asserted-by":"crossref","first-page":"3075","DOI":"10.1242\/dev.02473","article-title":"Axis specification and morphogenesis in the mouse embryo require Nap1, a regulator of WAVE-mediated actin branching","volume":"133","author":"Rakeman","year":"2006","journal-title":"Development"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0260","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1083\/jcb.200303023","article-title":"Molecular requirements for actin-based lamella formation in Drosophila S2 cells","volume":"162","author":"Rogers","year":"2003","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0265","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.tcb.2010.08.014","article-title":"WASH, WHAMM and JMY: regulation of Arp2\/3 complex and beyond","volume":"20","author":"Rottner","year":"2010","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0270","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1038\/nrm3492","article-title":"New insights into the regulation and cellular functions of the ARP2\/3 complex","volume":"14","author":"Rotty","year":"2013","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0275","doi-asserted-by":"crossref","first-page":"7694","DOI":"10.1073\/pnas.0511243103","article-title":"The bundling activity of vasodilator-stimulated phosphoprotein is required for filopodium formation","volume":"103","author":"Schirenbeck","year":"2006","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0280","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s12964-015-0119-5","article-title":"The NESH\/Abi-3-based WAVE2 complex is functionally distinct from the Abi-1-based WAVE2 complex","volume":"13","author":"Sekino","year":"2015","journal-title":"Cell Commun. Signal."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0285","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/S0962-8924(01)02237-1","article-title":"The lamellipodium: where motility begins","volume":"12","author":"Small","year":"2002","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0290","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1038\/sj.emboj.7600084","article-title":"Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation","volume":"23","author":"Steffen","year":"2004","journal-title":"EMBO J."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0295","doi-asserted-by":"crossref","first-page":"2581","DOI":"10.1091\/mbc.e05-11-1088","article-title":"Filopodia formation in the absence of functional WAVE- and Arp2\/3-complexes","volume":"17","author":"Steffen","year":"2006","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0300","doi-asserted-by":"crossref","first-page":"4572","DOI":"10.1242\/jcs.118232","article-title":"Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation","volume":"126","author":"Steffen","year":"2013","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0305","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.ejcb.2014.01.008","article-title":"Requirements for and consequences of Rac-dependent protrusion","volume":"93","author":"Steffen","year":"2014","journal-title":"Eur. J. Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0310","doi-asserted-by":"crossref","first-page":"4079","DOI":"10.1091\/mbc.e11-02-0121","article-title":"Membrane-targeted WAVE mediates photoreceptor axon targeting in the absence of the WAVE complex in Drosophila","volume":"22","author":"Stephan","year":"2011","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.ejcb.2017.08.003_bib0315","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.ceb.2005.12.003","article-title":"Protein complexes regulating Arp2\/3-mediated actin assembly","volume":"18","author":"Stradal","year":"2006","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0320","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/S0960-9822(01)00239-1","article-title":"The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia","volume":"11","author":"Stradal","year":"2001","journal-title":"Curr. Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0325","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1083\/jcb.145.5.1009","article-title":"Arp2\/3 complex and actin depolymerizing factor\/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia","volume":"145","author":"Svitkina","year":"1999","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0330","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1083\/jcb.201205058","article-title":"SCAR knockouts in Dictyostelium: WASP assumes SCAR\u2019s position and upstream regulators in pseudopods","volume":"198","author":"Veltman","year":"2012","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0335","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1083\/jcb.138.2.375","article-title":"The human Arp2\/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly","volume":"138","author":"Welch","year":"1997","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0340","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1242\/jcs.03024","article-title":"Rac1 and Rac2 regulate macrophage morphology but are not essential for migration","volume":"119","author":"Wheeler","year":"2006","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.ejcb.2017.08.003_bib0345","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/nature01770","article-title":"WAVE2 is required for directed cell migration and cardiovascular development","volume":"424","author":"Yamazaki","year":"2003","journal-title":"Nature"}],"container-title":["European Journal of Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171933517300900?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171933517300900?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,8,2]],"date-time":"2022-08-02T05:07:59Z","timestamp":1659416879000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0171933517300900"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12]]},"references-count":69,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["S0171933517300900"],"URL":"https:\/\/doi.org\/10.1016\/j.ejcb.2017.08.003","relation":{},"ISSN":["0171-9335"],"issn-type":[{"value":"0171-9335","type":"print"}],"subject":[],"published":{"date-parts":[[2017,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Differential functions of WAVE regulatory complex subunits in the regulation of actin-driven processes","name":"articletitle","label":"Article Title"},{"value":"European Journal of Cell Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejcb.2017.08.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}