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Opin. Genet. Dev."},{"key":"10.1016\/j.ejcb.2022.151244_bib190","doi-asserted-by":"crossref","first-page":"E5164","DOI":"10.1073\/pnas.1718946115","article-title":"Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson\u2019s disease","volume":"115","author":"Kim","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ejcb.2022.151244_bib191","doi-asserted-by":"crossref","first-page":"2996","DOI":"10.1091\/mbc.E18-12-0823","article-title":"Phosphorylation of nephrin induces phase separated domains that move through actomyosin contraction","volume":"30","author":"Kim","year":"2019","journal-title":"Mol. Biol. 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Commun."},{"key":"10.1016\/j.ejcb.2022.151244_bib197","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0304-3940(03)00506-8","article-title":"Possible involvement of Wiskott-Aldrich syndrome protein family in aberrant neuronal sprouting in Alzheimer\u2019s disease","volume":"346","author":"Kitamura","year":"2003","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.ejcb.2022.151244_bib198","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12964-018-0299-x","article-title":"Regulation of MRTF-A by JMY via a nucleation-independent mechanism","volume":"16","author":"Kluge","year":"2018","journal-title":"Cell Commun. Signal."},{"key":"10.1016\/j.ejcb.2022.151244_bib199","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1074\/jbc.273.1.291","article-title":"p140Sra-1 (specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase","volume":"273","author":"Kobayashi","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ejcb.2022.151244_bib200","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1038\/ejhg.2014.109","article-title":"Missense variant in CCDC22 causes X-linked recessive intellectual disability with features of Ritscher-Schinzel\/3C syndrome","volume":"23","author":"Kolanczyk","year":"2015","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1016\/j.ejcb.2022.151244_bib201","first-page":"5","article-title":"Evolution of the eukaryotic ARP2\/3 activators of the WASP family: WASP, WAVE, WASH, and WHAMM, and the proposed new family members WAWH and WAML","author":"Kollmar","year":"2012","journal-title":"BMC Res. 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Mol. Biol."},{"key":"10.1016\/j.ejcb.2022.151244_bib233","doi-asserted-by":"crossref","first-page":"5478","DOI":"10.1111\/febs.15328","article-title":"JMY expression by Sertoli cells contributes to mediating spermatogenesis in mice","volume":"287","author":"Liu","year":"2020","journal-title":"FEBS J."},{"key":"10.1016\/j.ejcb.2022.151244_bib234","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1111\/j.1462-5822.2004.00364.x","article-title":"Enterohaemorrhagic and enteropathogenic Escherichia coli use different mechanisms for actin pedestal formation that converge on N-WASP","volume":"6","author":"Lommel","year":"2004","journal-title":"Cell. 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Cell Biol."},{"key":"10.1016\/j.ejcb.2022.151244_bib288","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1038\/ncb1125","article-title":"Ptdlns(3,4,5)P 3 binding is necessary for WAVE2-induced formation of lamellipodia","volume":"6","author":"Oikawa","year":"2004","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ejcb.2022.151244_bib289","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.3233\/JAD-200019","article-title":"Examination of the effect of rare variants in TREM2, ABI3, and PLCG2 in LOAD through multiple phenotypes","volume":"77","author":"Olive","year":"2020","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.ejcb.2022.151244_bib290","doi-asserted-by":"crossref","first-page":"11351","DOI":"10.1073\/pnas.162376099","article-title":"Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses","volume":"99","author":"Orange","year":"2002","journal-title":"Proc. Natl. 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Cell Sci."},{"key":"10.1016\/j.ejcb.2022.151244_bib300","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.devcel.2012.12.014","article-title":"Cyclical action of the WASH complex: FAM21 and capping protein drive WASH recycling, not initial recruitment","volume":"24","author":"Park","year":"2013","journal-title":"Dev. 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Biol."},{"key":"10.1016\/j.ejcb.2022.151244_bib304","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1038\/nsmb796","article-title":"Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation","volume":"11","author":"Peterson","year":"2004","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.ejcb.2022.151244_bib305","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1091\/mbc.e14-06-1073","article-title":"COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A","volume":"26","author":"Phillips-Krawczak","year":"2015","journal-title":"Mol. Biol. 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Biol."},{"key":"10.1016\/j.ejcb.2022.151244_bib309","first-page":"220","article-title":"The wave complex associates with sites of saddle membrane curvature","author":"Pipathsouk","year":"2021","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ejcb.2022.151244_bib310","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1002\/cm.20323","article-title":"WAVE2 is regulated by multiple phosphorylation events within its VCA domain","volume":"66","author":"Pocha","year":"2009","journal-title":"Cell Motil. Cytoskelet."},{"key":"10.1016\/j.ejcb.2022.151244_bib311","unstructured":"Polesskaya, A., Boutillon, A., Yang, S., Wang, Y., Romero, S., Liu, Y., Lavielle, M., Vacher, S., Schnitzler, A., Molinie, N., Rocques, N., Fokin, A., Gu\u00e9rois, R., Bi\u00e8che, I., Chen, B., David, N.B., Gautreau, A.M., 2021. CYFIP2-containing WAVE complexes inhibit cell migration by a competition mechanism. bioRxiv 2020.07.02.184655."},{"key":"10.1016\/j.ejcb.2022.151244_bib312","first-page":"1","article-title":"Actin and actin-binding proteins","author":"Pollard","year":"2016","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.ejcb.2022.151244_bib313","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1126\/science.1175862","article-title":"Actin, a central player in cell shape and movement","volume":"326","author":"Pollard","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.ejcb.2022.151244_bib314","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/gcc.10289","article-title":"RAD21 and KIAA0196 at 8q24 are amplified and overexpressed in prostate cancer","volume":"39","author":"Porkka","year":"2004","journal-title":"Genes Chromosom. 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Cell Biol."},{"key":"10.1016\/j.ejcb.2022.151244_bib321","first-page":"92","article-title":"Human Cytomegalovirus UL135 Interacts with Host Adaptor Proteins To Regulate Epidermal Growth Factor Receptor and Reactivation from Latency Michael","author":"Rak","year":"2018","journal-title":"J. Virol."},{"key":"10.1016\/j.ejcb.2022.151244_bib322","doi-asserted-by":"crossref","first-page":"14671","DOI":"10.1073\/pnas.94.26.14671","article-title":"WIP, a protein associated with Wiskott-Aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells","volume":"94","author":"Ramesh","year":"1997","journal-title":"Proc. Natl. Acad. Sci. 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Microbiol"},{"key":"10.1016\/j.ejcb.2022.151244_bib325","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.ajhg.2017.08.007","article-title":"RAC1 missense mutations in developmental disorders with diverse phenotypes","volume":"101","author":"Reijnders","year":"2017","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ejcb.2022.151244_bib326","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1177\/0022034514544506","article-title":"Chronic periodontitis genome-wide association studies: gene-centric and gene set enrichment analyses","volume":"93","author":"Rhodin","year":"2014","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.ejcb.2022.151244_bib327","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/0092-8674(92)90164-8","article-title":"The small GTP-binding protein rac regulates growth factor-induced membrane ruffling","volume":"70","author":"Ridley","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.ejcb.2022.151244_bib328","doi-asserted-by":"crossref","first-page":"5725","DOI":"10.1128\/MCB.15.10.5725","article-title":"Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains","volume":"15","author":"Rivero-Lezcano","year":"1995","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.ejcb.2022.151244_bib329","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1083\/jcb.200303023","article-title":"Molecular requirements for actin-based lamella formation in Drosophila S2 cells","volume":"162","author":"Rogers","year":"2003","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ejcb.2022.151244_bib330","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1083\/jcb.150.6.1299","article-title":"Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4,5-bisphosphate","volume":"150","author":"Rohatgi","year":"2000","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ejcb.2022.151244_bib331","first-page":"122A","article-title":"N-WASP activates the Arp2\/3 complex and links Cdc42 and phosphoinositide signals to actin assembly","volume":"10","author":"Rohatgi","year":"1999","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.ejcb.2022.151244_bib332","doi-asserted-by":"crossref","first-page":"26448","DOI":"10.1074\/jbc.M103856200","article-title":"Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2\/3 pathway","volume":"276","author":"Rohatgi","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ejcb.2022.151244_bib333","doi-asserted-by":"crossref","first-page":"2585","DOI":"10.1093\/hmg\/ddr158","article-title":"Identification of a novel candidate gene for non-syndromic autosomal recessive intellectual disability: The WASH complex member swip","volume":"20","author":"Ropers","year":"2011","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ejcb.2022.151244_bib334","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.tcb.2010.08.014","article-title":"WASH, WHAMM and JMY: regulation of Arp2\/3 complex and beyond","volume":"20","author":"Rottner","year":"2010","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.ejcb.2022.151244_bib335","doi-asserted-by":"crossref","first-page":"R512","DOI":"10.1016\/j.cub.2021.01.086","article-title":"WAVE regulatory complex","volume":"31","author":"Rottner","year":"2021","journal-title":"Curr. 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