{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T05:18:22Z","timestamp":1784006302537,"version":"3.55.0"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Cardio-Thoracic Surgery"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1016\/j.ejcts.2010.10.003","type":"journal-article","created":{"date-parts":[[2010,11,20]],"date-time":"2010-11-20T09:36:18Z","timestamp":1290245778000},"page":"924-930","source":"Crossref","is-referenced-by-count":140,"title":["The Papworth Bleeding Risk Score: a stratification scheme for identifying cardiac surgery patients at risk of excessive early postoperative bleeding"],"prefix":"10.1093","volume":"39","author":[{"given":"Alain","family":"Vuylsteke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Pagel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Gerrard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samer","family":"Nashef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poppy","family":"Aldam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Utley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"key":"10.1016\/j.ejcts.2010.10.003_bib0005","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/0003-4975(94)00995-3","article-title":"Resternotomy for bleeding after cardiac operation: a marker for increased morbidity and mortality","volume":"59","author":"Unsworth-White","year":"1995","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0010","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1111\/j.1537-2995.2004.04144.x","article-title":"The independent association of massive blood loss with mortality in cardiac surgery","volume":"44","author":"Karkouti","year":"2004","journal-title":"Transfusion"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0015","doi-asserted-by":"crossref","first-page":"2544","DOI":"10.1161\/CIRCULATIONAHA.107.698977","article-title":"Increased mortality, post-operative morbidity and cost after red blood cell transfusion in patients having cardiac surgery","volume":"116","author":"Murphy","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0020","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1213\/00000539-199601000-00004","article-title":"Factors associated with excessive post-operative blood loss and hemostatic transfusion requirements: a multivariate analysis in cardiac surgical patients","volume":"82","author":"Despotis","year":"1996","journal-title":"Anesth Analg"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0025","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.athoracsur.2004.02.088","article-title":"Reexploration for bleeding after coronary artery bypass surgery: risk factors, outcomes, and the effect of time delay","volume":"78","author":"Karthik","year":"2004","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0030","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/S0022-5223(19)34348-X","article-title":"Predictors of excessive blood use after coronary artery bypass grafting. A multivariate analysis","volume":"98","author":"Ferraris","year":"1989","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0035","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1007\/BF03022795","article-title":"Prediction of massive blood transfusion in cardiac surgery","volume":"53","author":"Karkouti","year":"2006","journal-title":"Can J Anesth"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0040","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1161\/CIRCULATIONAHA.108.834275","article-title":"Safety and efficacy of recombinant activated factor VII: a randomized placebo-controlled trial in the setting of bleeding after cardiac surgery","volume":"120","author":"Gill","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0045","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1056\/NEJMoa051379","article-title":"The risk associated with aprotinin in cardiac surgery","volume":"354","author":"Mangano","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0050","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1213\/ANE.0b013e3181c0ea6d","article-title":"The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery","volume":"110","author":"Karkouti","year":"2010","journal-title":"Anesth Analg"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0055","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S1010-7940(99)00134-7","article-title":"European system for cardiac operative risk evaluation (EuroSCORE)","volume":"16","author":"Nashef","year":"1999","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0060","unstructured":"Physical Status: the use and interpretation of anthropometry. Report of a WHO expert committee. WHO technical report series 854. Geneva: World Health Organization; 1995."},{"key":"10.1016\/j.ejcts.2010.10.003_bib0065","doi-asserted-by":"crossref","first-page":"1908","DOI":"10.1016\/S0003-4975(96)00944-7","article-title":"Haemorrhage and the use of blood products after adult cardiac operations: myths and realities","volume":"62","author":"Belisle","year":"1996","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0070","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1016\/j.athoracsur.2006.06.020","article-title":"Indications for blood transfusion in cardiac surgery","volume":"82","author":"Murphy","year":"2006","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0075","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/S0022-5223(96)70380-X","article-title":"Reexploration for bleeding is a risk for adverse outcomes after cardiac operations","volume":"111","author":"Moulton","year":"1996","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0080","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1053\/jcan.2003.44","article-title":"Multivariate predictors of blood product use in cardiac surgery","volume":"17","author":"Parr","year":"2003","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0085","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/j.1445-5994.2005.00878.x","article-title":"Recombinant factor VIIa as an adjunctive therapy for patients requiring large volume transfusion: a pharmacoeconomic evaluation","volume":"35","author":"Loudon","year":"2005","journal-title":"Intern Med J"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0090","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1001\/jama.295.3.293","article-title":"Thromboembolic adverse events after use of recombinant human coagulation factor VIIa","volume":"295","author":"O\u2019Connell","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0095","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.ccc.2005.04.003","article-title":"Bleeding in cardiac surgery: its prevention and treatment \u2013 an evidence based review","volume":"21","author":"Whitlock","year":"2005","journal-title":"Crit Care Clin"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0100","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1097\/00001721-200302000-00005","article-title":"Fibrinolytic activity and bleeding after cardiac surgery with cardiopulmonary bypass and low dose aprotinin therapy","volume":"14","author":"Kuepper","year":"2003","journal-title":"Blood Coagul Fibrinolysis"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0105","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1097\/00003643-200706002-00004","article-title":"Preventing and managing post-operative bleeding in cardiac surgery by controlling disseminated intravascular coagulation","volume":"24","author":"Szefner","year":"2007","journal-title":"Eur J Anaesthesiol"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0110","first-page":"352","article-title":"Re-exploration for hemorrhage following open heart surgery differentiation on the causes of bleeding and the impact on patient outcomes","volume":"7","author":"Hall","year":"2001","journal-title":"Ann Thorac Cardiovasc Surg"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0115","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.jtcvs.2005.02.025","article-title":"Hemodilution and surgical hemostasis contribute significantly to transfusion requirements in patients undergoing coronary artery bypass","volume":"130","author":"Dial","year":"2005","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0120","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1046\/j.1537-2995.2001.41101193.x","article-title":"A multivariate model for predicting the need for blood transfusion in patients undergoing first time elective coronary bypass graft surgery","volume":"41","author":"Karkouki","year":"2001","journal-title":"Transfusion"},{"key":"10.1016\/j.ejcts.2010.10.003_bib0125","doi-asserted-by":"crossref","first-page":"2523","DOI":"10.1161\/CIRCULATIONAHA.107.739094","article-title":"Blood transfusion in cardiac surgery \u2013 a silent epidemic revisited","volume":"116","author":"Rawn","year":"2007","journal-title":"Circulation"}],"container-title":["European Journal of Cardio-Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ejcts\/article-pdf\/39\/6\/924\/14030255\/39-6-924.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,13]],"date-time":"2020-06-13T23:48:33Z","timestamp":1592092113000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejcts\/article-lookup\/doi\/10.1016\/j.ejcts.2010.10.003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S1010794010008614"],"URL":"https:\/\/doi.org\/10.1016\/j.ejcts.2010.10.003","relation":{},"ISSN":["1010-7940"],"issn-type":[{"value":"1010-7940","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6]]}}}