{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T23:04:42Z","timestamp":1770073482658,"version":"3.49.0"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Diabetes mellitus in patients with coronary artery disease is associated with poor outcome. In this study, the relation between myocardial viability, diabetes, coronary revascularisation and outcome was evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>129 patients (31 diabetic, 98 non-diabetic) with ischaemic cardiomyopathy underwent dobutamine stress echocardiography to assess myocardial viability. Patients with \u22654 viable segments were defined as viable and patients with &amp;lt;&amp;lt;4 viable segments as nonviable. Left ventricular ejection fraction (LVEF) was assessed before and 9\u201312 months post-revascularisation. At the same time-points, LV volumes were measured to evaluate LV remodelling. Finally, cardiac events were noted during 5-year follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The extent of viable myocardium was comparable between diabetic and non-diabetic patients. After revascularisation, LVEF increased \u22655% in 44% of diabetic and in 40% of non-diabetic patients. LVEF only improved in patients with viable myocardium. Ongoing LV remodelling occurred in 36% and 35% of diabetic and non-diabetic patients respectively, and was related to non-viability, whereas viability protected against ongoing LV remodelling, both in diabetic and non-diabetic patients. Viability was the only predictor of survival after revascularisation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Diabetic, viable patients with ischaemic LV dysfunction exhibit improvement in LVEF post-revascularisation with prevention of ongoing LV remodelling, similar to non-diabetic patients. Myocardial viability was also the only predictor of long-term outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ejheart.2005.07.014","type":"journal-article","created":{"date-parts":[[2005,9,27]],"date-time":"2005-09-27T10:19:28Z","timestamp":1127816368000},"page":"314-320","source":"Crossref","is-referenced-by-count":5,"title":["Benefits of Coronary Revascularisation in Diabetic and Non-Diabetic Patients with Ischaemic Cardiomyopathy: Role of Myocardial Viability"],"prefix":"10.1093","volume":"8","author":[{"given":"Vittoria","family":"Rizzello","sequence":"first","affiliation":[{"name":"Department of Cardiology, The Catholic University , Rome ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Don","family":"Poldermans","sequence":"additional","affiliation":[{"name":"Department of Cardiology , Thoraxcenter Room Ba 300, Erasmus MC, Dr. Molewaterplein 40, 3015, GD Rotterdam ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Biagini","sequence":"additional","affiliation":[{"name":"Department of Cardiology , Thoraxcenter Room Ba 300, Erasmus MC, Dr. Molewaterplein 40, 3015, GD Rotterdam ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arend F.L.","family":"Schinkel","sequence":"additional","affiliation":[{"name":"Department of Cardiology , Thoraxcenter Room Ba 300, Erasmus MC, Dr. Molewaterplein 40, 3015, GD Rotterdam ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Boersma","sequence":"additional","affiliation":[{"name":"Department of Cardiology , Thoraxcenter Room Ba 300, Erasmus MC, Dr. Molewaterplein 40, 3015, GD Rotterdam ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdou","family":"Elhendy","sequence":"additional","affiliation":[{"name":"Department of Cardiology , Thoraxcenter Room Ba 300, Erasmus MC, Dr. Molewaterplein 40, 3015, GD Rotterdam ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiola B.","family":"Sozzi","sequence":"additional","affiliation":[{"name":"Department of Cardiology , Thoraxcenter Room Ba 300, Erasmus MC, Dr. Molewaterplein 40, 3015, GD Rotterdam ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Maat","sequence":"additional","affiliation":[{"name":"Department of Cardiology , Thoraxcenter Room Ba 300, Erasmus MC, Dr. Molewaterplein 40, 3015, GD Rotterdam ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos R.T.C.","family":"Roelandt","sequence":"additional","affiliation":[{"name":"Department of Cardiology , Thoraxcenter Room Ba 300, Erasmus MC, Dr. Molewaterplein 40, 3015, GD Rotterdam ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeroen J.","family":"Bax","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Center , Leiden ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2006,5,13]]},"reference":[{"key":"2026020203520854000_ejhf2005-07-014-bib-0001","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1161\/01.CIR.87.5.1630","article-title":"Quantitative planar rest-redistribution 201Tl imaging in detection of myocardial viability and prediction of improvement in left ventricular function after coronary bypass surgery in patients with severely depressed left ventricular function","volume":"87","author":"Ragosta","year":"1993","journal-title":"Circulation"},{"key":"2026020203520854000_ejhf2005-07-014-bib-0002","doi-asserted-by":"crossref","first-page":"II37","DOI":"10.1161\/01.CIR.92.9.37","article-title":"Preoperative selection of patients with severely impaired left ventricular function for coronary revascularization. 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