{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T19:31:03Z","timestamp":1791142263100,"version":"4.1.0"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2007,12,1]],"date-time":"2007-12-01T00:00:00Z","timestamp":1196467200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Recent registries have shown that recommended drugs for the treatment of chronic heart failure (CHF) are under-prescribed in daily practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To determine prescription rates of CHF drugs, and to assess predictive factors for drug prescription using data from a large panel of French cardiologists.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>We included 1919 outpatients, with NYHA class II\u2013IV heart failure and a left ventricular ejection fraction &amp;lt;40%. The most frequently prescribed drugs were diuretics (83%), angiotensin converting enzyme inhibitors (ACE-I) (71%), beta-blockers (65%), spironolactone (35%) and angiotensin receptor blockers (ARB) (21%); 61% of patients received a combination of a beta-blocker and an ACE-I or ARB. Target doses were reached in 49% of the patients for ACE-I, but in only 18% for beta-blockers and in 9% for ARBs. Multivariate analyses showed that age &amp;gt;75 years was an independent factor associated with under-prescription of ACE-I-ARBs, beta-blockers or spironolactone. Renal failure was associated with a lower prescription of ACE-I-ARB and spironolactone, and asthma was a predictor of under-prescription of beta-blockers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this contemporary survey, prescription rates of CHF drugs were higher than previously reported. However, dosages were lower than those recommended in guidelines. Age remained an independent predictor of under-prescription of CHF drugs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ejheart.2007.09.008","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T10:24:10Z","timestamp":1196072650000},"page":"1205-1211","source":"Crossref","is-referenced-by-count":106,"title":["Is the Gap Between Guidelines and Clinical Practice in Heart Failure Treatment Being Filled? Insights from the IMPACT RECO Survey"],"prefix":"10.1093","volume":"9","author":[{"given":"P.","family":"de Groote","sequence":"first","affiliation":[{"name":"Service de Cardiologie C, H\u00f4pital Cardiologique , CHRU, Bd du Pr Jules Leclercq, 59037 Lille Cedex ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Isnard","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Cardiologie, H\u00f4pital Piti\u00e9-Salp\u00eatri\u00e8re &, Universit\u00e9 Pierre et Marie Curie , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Assyag","sequence":"additional","affiliation":[{"name":"Service Cardiologie, H\u00f4pital Saint Antoine , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Clerson","sequence":"additional","affiliation":[{"name":"Orgametrie , Roubaix ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Ducardonnet","sequence":"additional","affiliation":[{"name":"Institut C\u0153ur Effort Sant\u00e9 , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Galinier","sequence":"additional","affiliation":[{"name":"F\u00e9d\u00e9ration des Services de Cardiologie, CHU Rangueil , Toulouse ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Jondeau","sequence":"additional","affiliation":[{"name":"Service de Cardiologie, H\u00f4pital Ambroise Par\u00e9 , Boulogne ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Leurs","sequence":"additional","affiliation":[{"name":"AstraZeneca , Rueil-Malmaison ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.-F.","family":"Th\u00e9baut","sequence":"additional","affiliation":[{"name":"Centre Alfred Kassler , Sarcelles ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Komajda","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Cardiologie, H\u00f4pital Piti\u00e9-Salp\u00eatri\u00e8re &, Universit\u00e9 Pierre et Marie Curie , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2008,12,11]]},"reference":[{"key":"2026020203501628000_ejhf2007-09-008-bib-0001","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1056\/NEJM198706043162301","article-title":"Effects of enalapril on mortality in severe congestive heart failure. 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