{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T03:00:09Z","timestamp":1790305209001,"version":"4.1.0"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Although heart failure (HF) is frequent in elderly patients, few studies have focused on patients older than 80 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To evaluate the clinical features, treatment and long-term prognosis of HF in patients older than 80 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>Consecutive patients hospitalised for a first HF episode in the Somme Department (France) during 2000 were prospectively included. Of the 799 included patients, 305 (38%) were aged over 80 years. The elderly patients were mostly women with a high prevalence of atrial fibrillation, ischaemic and hypertensive heart disease. Ejection fraction (EF) was assessed in 68.5% of elderly patients and 61% had EF \u226550%. Angiotensin-converting enzyme inhibitors, beta-blockers, oral anticoagulants and statins were prescribed less frequently in elderly patients. The 5-year survival in elderly patients was 19%, dramatically lower than the survival of age- and sex-matched general population (48%). Cardiovascular causes were recorded in over 60% of deaths. On multivariable analysis, cancer, renal insufficiency, old myocardial infarction, diabetes, hyponatraemia and age were predictors of mortality in elderly patients. Reduced EF was a potent predictor of death (HR 1.72, 95%CI 1.24\u20132.37, p=0.001) in elderly patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Long-term prognosis in HF patients older than 80 years is poor, with a dramatic excess mortality compared to the elderly general population. Life-saving drugs are largely underused in elderly HF patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ejheart.2007.11.004","type":"journal-article","created":{"date-parts":[[2007,12,26]],"date-time":"2007-12-26T11:24:39Z","timestamp":1198668279000},"page":"78-84","source":"Crossref","is-referenced-by-count":74,"title":["Long-Term Survival in Patients Older than 80 Years Hospitalised for Heart Failure. A 5-Year Prospective Study"],"prefix":"10.1093","volume":"10","author":[{"given":"Ha\u00effa","family":"Mahjoub","sequence":"first","affiliation":[{"name":"INSERM, ERI 12 Amiens, France and University Hospital Amiens \u00a0","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Rusinaru","sequence":"additional","affiliation":[{"name":"INSERM, ERI 12 Amiens, France and University Hospital Amiens \u00a0","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicky","family":"Souli\u00e8re","sequence":"additional","affiliation":[{"name":"INSERM, ERI 12 Amiens, France and University Hospital Amiens \u00a0","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chlo\u00e9","family":"Durier","sequence":"additional","affiliation":[{"name":"INSERM, ERI 12 Amiens, France and University Hospital Amiens \u00a0","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"Peltier","sequence":"additional","affiliation":[{"name":"INSERM, ERI 12 Amiens, France and University Hospital Amiens \u00a0","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Tribouilloy","sequence":"additional","affiliation":[{"name":"INSERM, ERI 12 Amiens, France and University Hospital Amiens \u00a0","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,1,13]]},"reference":[{"key":"2026020203442573800_ejhf2007-11-004-bib-0001","volume-title":"Heart disease and stroke statistics \u2014 2007","author":"American Heart Association","year":"2007"},{"key":"2026020203442573800_ejhf2007-11-004-bib-0002","first-page":"5","article-title":"Medical therapy and prognosis in chronic heart failure. 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